LOCUS       NM_145710               1336 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus oocyte specific homeobox 6 (Obox6), mRNA.
ACCESSION   NM_145710
VERSION     NM_145710.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Ji,S., Chen,F., Stein,P., Wang,J., Zhou,Z., Wang,L., Zhao,Q.,
            Lin,Z., Liu,B., Xu,K., Lai,F., Xiong,Z., Hu,X., Kong,T., Kong,F.,
            Huang,B., Wang,Q., Xu,Q., Fan,Q., Liu,L., Williams,C.J.,
            Schultz,R.M. and Xie,W.
  TITLE     OBOX regulates mouse zygotic genome activation and early
            development
  JOURNAL   Nature 620 (7976), 1047-1053 (2023)
   PUBMED   37459895
REFERENCE   2  (bases 1 to 1336)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 1336)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1336)
  AUTHORS   Chung,Y.C., Tsai,Y.J., Shiu,T.Y., Sun,Y.Y., Wang,P.F. and Chen,C.L.
  TITLE     Screening large numbers of expression patterns of transcription
            factors in late stages of the mouse thymus
  JOURNAL   Gene Expr Patterns 11 (1-2), 84-92 (2011)
   PUBMED   20932939
REFERENCE   5  (bases 1 to 1336)
  AUTHORS   Cheng,W.C., Hsieh-Li,H.M., Yeh,Y.J. and Li,H.
  TITLE     Mice lacking the Obox6 homeobox gene undergo normal early embryonic
            development and are fertile
  JOURNAL   Dev Dyn 236 (9), 2636-2642 (2007)
   PUBMED   17676645
  REMARK    GeneRIF: other members of the Obox gene family can compensate for
            Obox6 function during embryogenesis
REFERENCE   6  (bases 1 to 1336)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   7  (bases 1 to 1336)
  AUTHORS   Rajkovic,A., Yan,C., Yan,W., Klysik,M. and Matzuk,M.M.
  TITLE     Obox, a family of homeobox genes preferentially expressed in germ
            cells
  JOURNAL   Genomics 79 (5), 711-717 (2002)
   PUBMED   11991721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN712286.1, BY731792.1, CN721150.1 and BG069935.2.
            
            On Feb 7, 2007 this sequence version replaced NM_145710.1.
            
            CCDS Note: The coding region has been updated to include an
            additional segment in the mid coding region that is more supported
            by the available transcript and protein data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY731792.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-619               CN712286.1         1-619
            620-710             BY731792.1         619-709
            711-772             CN721150.1         383-444
            773-1336            BG069935.2         1-564               c
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 8.59 cM"
     gene            1..1336
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /note="oocyte specific homeobox 6"
                     /db_xref="GeneID:252830"
                     /db_xref="MGI:MGI:2149036"
     exon            1..49
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /inference="alignment:Splign:2.1.0"
     exon            50..635
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1109
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /codon_start=1
                     /product="oocyte-specific homeobox protein 6"
                     /protein_id="NP_663756.2"
                     /db_xref="CCDS:CCDS20839.2"
                     /db_xref="GeneID:252830"
                     /db_xref="MGI:MGI:2149036"
                     /translation="MLQYNQSPHMPQDPSLHSKFQMSSSAPIEISFQMHQEPARNLPF
                     QMCQSPLVIPRSPMQSSHSVPERDLCPQESQGPSGKSSIQMQPGLVMDPALPILRSLL
                     MHSPHQIPSRSSVRAGFQGSLGPMVRSPSYGDRRVSLVTPRKHRKIRTVYTEEQKCVL
                     KKHFHKCTYPSREQRMALAVLVGVTANEIQIWFKNHRAKSKRESLQNVPAALPETNGS
                     SEAVSESVHFPDSLPVVASANGESMWSGTFGEDSIPNLNWSQESSPPHYQACDSARYC
                     PQEYLLNGHAPVTAWNSGQSVAVEVQTGLAVAEAPVVMVASTQGPEYAQDSGPSTEEL
                     WQRVLEDFDELGD"
     exon            636..1336
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1305..1310
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /note="hexamer: AATAAA"
     polyA_site      1331
                     /gene="Obox6"
                     /gene_synonym="D17Ertd599e"
                     /note="major polyA site"
ORIGIN      
        1 agaagtcaaa cagaggattg ggcaaactat agcaaccctc tgatttcagg ttctcctgta
       61 ggaacatgct tcaatacaat cagagcccac atatgcccca agatccctcc ttgcattcaa
      121 aattccaaat gtcttcaagt gcacccatag aaatcagttt tcaaatgcat caagaacctg
      181 caaggaattt gcctttccaa atgtgccaga gtcctctagt gatcccaaga agtccaatgc
      241 aatcaagtca ttcagtccct gaaagggacc tatgtccgca agagtcccaa ggtccatcag
      301 gaaaatcaag tatacaaatg caaccaggtc ttgtaatgga cccagcttta ccaattctga
      361 gaagcctctt aatgcattca cctcatcaga taccttcaag atcctcagtg agagctggtt
      421 tccagggttc tctaggacct atggtgcggt cacctagtta tggtgaccga cgagtcagcc
      481 ttgtgactcc aaggaagcac cggaaaatac gcactgtata caccgaggaa caaaagtgtg
      541 tgctgaaaaa acattttcat aagtgcacat acccaagccg ggagcaacgc atggcactgg
      601 cagttttggt tggtgtcaca gcaaatgaga tccagatctg gttcaagaac caccgggcta
      661 agtccaagcg ggagagtctc cagaatgttc cagcagcact gccagagaca aatggaagct
      721 ctgaagctgt ttctgagtca gtccactttc ctgattcctt acccgttgtt gcttctgcca
      781 atggagagtc catgtggtca ggcacatttg gtgaggattc cattcccaac ctcaactgga
      841 gccaggaatc ttctccgcct cattatcagg cctgtgatag tgccaggtat tgtccgcaag
      901 aatacctgct taatggccat gcccctgtta cagcttggaa ctctggtcaa tcagtagcag
      961 ttgaagtcca gactggctta gcagtagctg aagctccagt cgtcatggta gcttccaccc
     1021 aaggtccaga gtatgctcaa gattcaggtc catctacaga ggagctctgg caacgggttc
     1081 ttgaagactt tgatgagttg ggggattgag atacaccccc ataaaacacc tctcaccccc
     1141 cttgacttat ccaggccttt atagaaagga agatgtttgt tagtgtattt ggagaaatta
     1201 agtaggtcta tctgtagtag tttcatgtca ctggtttatg tagtgggatt gtttaaaaaa
     1261 catggaaaat attcctccct tattgttgaa ttacatattc tttaaataaa agaaagaaaa
     1321 catttactgg agaatt
//
