LOCUS       NM_145708               1343 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus oocyte specific homeobox 2 (Obox2), mRNA.
ACCESSION   NM_145708 NR_003269
VERSION     NM_145708.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Ji,S., Chen,F., Stein,P., Wang,J., Zhou,Z., Wang,L., Zhao,Q.,
            Lin,Z., Liu,B., Xu,K., Lai,F., Xiong,Z., Hu,X., Kong,T., Kong,F.,
            Huang,B., Wang,Q., Xu,Q., Fan,Q., Liu,L., Williams,C.J.,
            Schultz,R.M. and Xie,W.
  TITLE     OBOX regulates mouse zygotic genome activation and early
            development
  JOURNAL   Nature 620 (7976), 1047-1053 (2023)
   PUBMED   37459895
REFERENCE   2  (bases 1 to 1343)
  AUTHORS   Cheng,W.C., Hsieh-Li,H.M., Yeh,Y.J. and Li,H.
  TITLE     Mice lacking the Obox6 homeobox gene undergo normal early embryonic
            development and are fertile
  JOURNAL   Dev Dyn 236 (9), 2636-2642 (2007)
   PUBMED   17676645
REFERENCE   3  (bases 1 to 1343)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   4  (bases 1 to 1343)
  AUTHORS   Rajkovic,A., Yan,C., Yan,W., Klysik,M. and Matzuk,M.M.
  TITLE     Obox, a family of homeobox genes preferentially expressed in germ
            cells
  JOURNAL   Genomics 79 (5), 711-717 (2002)
   PUBMED   11991721
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV663188.1, BC094912.1 and DV647958.1.
            
            On Apr 7, 2010 this sequence version replaced NM_145708.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094912.1, DV660385.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               DV663188.1         1-120
            121-740             BC094912.1         1-620
            741-871             DV647958.1         129-259
            872-1343            BC094912.1         752-1223
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 8.46 cM"
     gene            1..1343
                     /gene="Obox2"
                     /note="oocyte specific homeobox 2"
                     /db_xref="GeneID:246792"
                     /db_xref="MGI:MGI:2149033"
     exon            1..156
                     /gene="Obox2"
                     /inference="alignment:Splign:2.1.0"
     exon            157..418
                     /gene="Obox2"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..657
                     /gene="Obox2"
                     /codon_start=1
                     /product="inactive oocyte-specific homeobox protein 2"
                     /protein_id="NP_663754.2"
                     /db_xref="CCDS:CCDS52034.1"
                     /db_xref="GeneID:246792"
                     /db_xref="MGI:MGI:2149033"
                     /translation="MAEGPSLHPKLQVDSNIPIEISSQIPQEPARNLAFQMRQSPLVT
                     PGSTTKSSLSVPERNLLKQESEGPSRQSGCMPLSDKYVNKQTSPMASRKFRKERTVYT
                     KEEQGLLQKHFDECSTQTRRKLWSWHYQLVLQRGRLRYGSRTTELSTGR"
     exon            419..617
                     /gene="Obox2"
                     /inference="alignment:Splign:2.1.0"
     exon            618..1329
                     /gene="Obox2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgagaattaa ggatttgaat attgcaagtg ggtggagcca gcgtgaagga ggagcattga
       61 attccaagtt tgcagagata tataagggca ggtcttctga gtagaattaa aacagccaga
      121 ggatttagca agttacagca accctctgga ttcctggtta tccagtacag gaacatactc
      181 caataaattc agaacacaca aatggcggaa ggtccctcct tgcatccaaa actccaagtg
      241 gattcgaata tacccataga aataagttcc caaatacctc aagaaccggc aaggaactta
      301 gcttttcaaa tgcgtcagag tcccctagtg accccaggaa gtacaacgaa atcaagtctt
      361 tcagtccctg aaaggaacct acttaagcaa gagtctgaag gaccatcaag acaatcaggt
      421 tgtatgccac tgtcagataa atatgttaac aaacaaacta gcccaatggc ttcaagaaag
      481 tttcgaaaag aacgaactgt gtacaccaaa gaagagcagg gcctgctgca aaaacatttt
      541 gatgagtgca gtacccaaac aagaagaaaa ttgtggagct ggcactatca gttggtgtta
      601 caaagaggga gattaagata tggttcaaga acaaccgagc taagtacagg cagatgaacc
      661 tccagaatat tgaacaagca ctgccagagt caaatggaag ctctaaagcg gtttctgagt
      721 caacccattt tcctgttgtt gcctctgaca atggagagtc catgtgttca ggcacatttg
      781 gtgaggattc cattcccaaa ttcaactgca gctaggaatc ttccctgcat tgttttcagg
      841 cctgagatgg ggccatgtgt tgtacgcaag aatatgtgct tgatggccat acccctgtta
      901 cagcttggaa ctctggtcaa tcagcagcag ttgaatatca cacttagcag tagctgaagc
      961 tccagtcggg ctggcatatg ctgcccaagc cccagaggat gctcacaatt caggtccatc
     1021 tgcagacaag ctctggcaaa ggatccttga agacttttga cacatcagat gactgtcttg
     1081 ccatgagaaa cccctccact ccagcttaca cctctcaggt ccttgacgag tccaacctta
     1141 cagccatgaa gaagtgtgtt atatacacct ttattctctg tatttggaga aataaccagt
     1201 cttatctgta gaagcatcat accactgtgt tttatgtagt gcgattgttt gaaattcagt
     1261 ttaggtctta attttttatt gttagagtat atgttcatta aataaaagga gaaaatagta
     1321 cttttaaaaa aaaaaaaaaa aaa
//
