LOCUS       NM_145210               1715 bp    mRNA    linear   ROD 13-AUG-2022
DEFINITION  Mus musculus 2'-5' oligoadenylate synthetase 1E (Oas1e), transcript
            variant 2, mRNA.
ACCESSION   NM_145210 XM_993988
VERSION     NM_145210.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1715)
  AUTHORS   He Y, Chen Q, Dai J, Cui Y, Zhang C, Wen X, Li J, Xiao Y, Peng X,
            Liu M, Shen B, Sha J, Hu Z, Li J and Shu W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   2  (bases 1 to 1715)
  AUTHORS   Kim J, Kim J, Jeong J, Hong SH, Kim D, Choi S, Choi I, Oh JS and
            Cho C.
  TITLE     Identification of a novel embryo-prevalent gene, Gm11545, involved
            in preimplantation embryogenesis in mice
  JOURNAL   FASEB J 33 (10), 11326-11337 (2019)
   PUBMED   31322925
REFERENCE   3  (bases 1 to 1715)
  AUTHORS   Kristiansen H, Gad HH, Eskildsen-Larsen S, Despres P and Hartmann
            R.
  TITLE     The oligoadenylate synthetase family: an ancient protein family
            with multiple antiviral activities
  JOURNAL   J Interferon Cytokine Res 31 (1), 41-47 (2011)
   PUBMED   21142819
  REMARK    Review article
REFERENCE   4  (bases 1 to 1715)
  AUTHORS   Evsikov AV, Graber JH, Brockman JM, Hampl A, Holbrook AE, Singh P,
            Eppig JJ, Solter D and Knowles BB.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   5  (bases 1 to 1715)
  AUTHORS   Mashimo T, Glaser P, Lucas M, Simon-Chazottes D, Ceccaldi PE,
            Montagutelli X, Despres P and Guenet JL.
  TITLE     Structural and functional genomics and evolutionary relationships
            in the cluster of genes encoding murine 2',5'-oligoadenylate
            synthetases
  JOURNAL   Genomics 82 (5), 537-552 (2003)
   PUBMED   14559211
REFERENCE   6  (bases 1 to 1715)
  AUTHORS   Kakuta S, Shibata S and Iwakura Y.
  TITLE     Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene
            family
  JOURNAL   J Interferon Cytokine Res 22 (9), 981-993 (2002)
   PUBMED   12396720
REFERENCE   7  (bases 1 to 1715)
  AUTHORS   Perelygin AA, Scherbik SV, Zhulin IB, Stockman BM, Li Y and Brinton
            MA.
  TITLE     Positional cloning of the murine flavivirus resistance gene
  JOURNAL   Proc Natl Acad Sci U S A 99 (14), 9322-9327 (2002)
   PUBMED   12080145
REFERENCE   8  (bases 1 to 1715)
  AUTHORS   Eskildsen S, Hartmann R, Kjeldgaard NO and Justesen J.
  TITLE     Gene structure of the murine 2'-5'-oligoadenylate synthetase family
  JOURNAL   Cell Mol Life Sci 59 (7), 1212-1222 (2002)
   PUBMED   12222967
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK087823.1 and DV662831.1.
            
            On Jul 21, 2009 this sequence version replaced NM_145210.1.
            
            Transcript Variant: This variant (2) uses an alternate splice
            junction in the 3' end compared to variant 1. The resulting isoform
            (2) has a shorter and distinct C-terminus compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK087823.1, BC094918.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1123              AK087823.1         1-1123
            1124-1715           DV662831.1         157-748
FEATURES             Location/Qualifiers
     source          1..1715
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 60.64 cM"
     gene            1..1715
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /note="2'-5' oligoadenylate synthetase 1E"
                     /db_xref="GeneID:231699"
                     /db_xref="MGI:MGI:2180856"
     exon            1..215
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1103
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /note="isoform 2 is encoded by transcript variant 2;
                     2'-5'olygoadenylate synthetase 1E; 2'-5' oligoadenylate
                     synthetase-like 7; 2,5-oligoadenylate synthetase-like 7"
                     /codon_start=1
                     /product="2'-5' oligoadenylate synthetase 1E isoform 2"
                     /protein_id="NP_660211.2"
                     /db_xref="CCDS:CCDS39243.1"
                     /db_xref="GeneID:231699"
                     /db_xref="MGI:MGI:2180856"
                     /translation="MARELFRTPIWRLDNFIEDQLLPDTTFLTELRADIDSISAFLKE
                     RCFQGATHPMRVARVVMGGSYDEHNALKGRSEANMVVFFNDLTSFEDQLKWQQVFIEE
                     IRKHLLQLQQEKPCKLKFEVQSSEEPNTRSLTFKLCSPERQQEVEFDVQPAYDALYEG
                     GYCKSFESINYNKVYAQLIHECTTLEKEGEFSICFTDLHQSFLRYRAPKLWNLIRLVK
                     HWYQLCKEKLRGPLPPQYALELLTVYVWEFGVQDSFGLHAAQCFRTVLELVTKYKCLL
                     IYWTWFYDFRPEISDYLHGQIKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWIH
                     SNFFRNCDMSLVNGWEVSPEKQ"
     exon            216..504
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
     exon            505..701
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
     exon            702..934
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1088
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1715
                     /gene="Oas1e"
                     /gene_synonym="oasl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctgcagtc agcaaacact cctggcctca ggatggcgag ggaactcttc agaaccccaa
       61 tctggaggct ggataacttc atagaggatc aactccttcc tgacaccacc ttccttactg
      121 agctcagagc agacatcgac tccataagtg ctttcctgaa ggagagatgc ttccaaggtg
      181 ccacccaccc tatgagggtc gccagggttg tgatgggagg ctcctatgat gaacacaatg
      241 cactcaaggg aaggtcagag gccaacatgg tggtgttctt taatgatctc accagctttg
      301 aggaccagtt aaagtggcag caagtgttca ttgaagaaat tcggaaacac ctgctccagt
      361 tgcagcaaga gaagccatgt aaactcaagt ttgaggtgca gagctcagag gagcccaaca
      421 ccaggtctct gaccttcaag ctgtgctccc cagagcgcca gcaggaggtg gaatttgatg
      481 tgcagccagc ctatgatgct ctgtatgaag ggggatactg caagtccttt gaatccatta
      541 actacaacaa agtctacgcc caactcatcc atgagtgcac caccctggag aaggagggcg
      601 agttctccat ctgcttcacc gaccttcatc agagcttcct gaggtatcgt gcgcccaagc
      661 tctggaacct catccgtctg gtcaagcact ggtatcaact gtgtaaggag aagctgaggg
      721 gaccgctgcc tccacagtat gccctggagc tgctcacagt ctacgtctgg gaatttgggg
      781 tccaagacag ctttggactc catgcagccc agtgcttccg aacggtctta gaactggtca
      841 ccaagtacaa atgccttcta atctactgga catggtttta tgactttcga cctgagatct
      901 ctgactacct gcacggacag atcaaaaaag ccaggcctct gatcctggat ccggcagacc
      961 caacaaggaa cgtggctggt tcagacttac aggcatggga cctgctggca aaggaggctc
     1021 agacctggat acattcaaat ttttttagga actgtgatat gtcccttgtg aatggctggg
     1081 aagtgtcgcc agagaaacaa taatgtgtct tccagtgagc agtgtagcac ttgcctagaa
     1141 ggctccagag tcaggatcat gtgctcctcc gctgtaagac tttgacctag agaggacagg
     1201 atggtgctca tgtctccagc gaggggtatc caacctgtga ttagactcca ggcttctgat
     1261 ccctgcctgc ccatggatag ccttcctcac aggctgcttc atctgcctta gcttccaaca
     1321 gtgttctctg ggagtcaggc tgtgatggac agagaagaac gcaagctcga cttccatctg
     1381 tccacctgtt gggaggttct gtccaatagt ggctgatcgt catcatcaaa tcacagcaag
     1441 ccatggggga gggtgcactc tgagggagtc ctcagaccac acagaaactt ttcagcagtg
     1501 catgtggccc tggcaccctg ggaatctggc cagtgttcat caaggtgcac tgtttctaca
     1561 acatgcaggc cgggtttatg gcagttcggg aaaataaaac tgcggatact ttaaatttat
     1621 gactttaaaa tttaggtgta tgtgtgtgtg tgtgtatata tatatataat ttgaagcact
     1681 gaattaaatc aaaatgcatt gaattaaact aaaat
//
