LOCUS       NM_133893               1750 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus 2'-5' oligoadenylate synthetase 1D (Oas1d), mRNA.
ACCESSION   NM_133893
VERSION     NM_133893.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1750)
  AUTHORS   Kristiansen,H., Gad,H.H., Eskildsen-Larsen,S., Despres,P. and
            Hartmann,R.
  TITLE     The oligoadenylate synthetase family: an ancient protein family
            with multiple antiviral activities
  JOURNAL   J Interferon Cytokine Res 31 (1), 41-47 (2011)
   PUBMED   21142819
  REMARK    Review article
REFERENCE   2  (bases 1 to 1750)
  AUTHORS   Joshi,S., Davies,H., Sims,L.P., Levy,S.E. and Dean,J.
  TITLE     Ovarian gene expression in the absence of FIGLA, an oocyte-specific
            transcription factor
  JOURNAL   BMC Dev Biol 7, 67 (2007)
   PUBMED   17567914
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1750)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   4  (bases 1 to 1750)
  AUTHORS   Yan,W., Ma,L., Stein,P., Pangas,S.A., Burns,K.H., Bai,Y.,
            Schultz,R.M. and Matzuk,M.M.
  TITLE     Mice deficient in oocyte-specific oligoadenylate synthetase-like
            protein OAS1D display reduced fertility
  JOURNAL   Mol Cell Biol 25 (11), 4615-4624 (2005)
   PUBMED   15899864
  REMARK    GeneRIF: OAS1D suppresses the interferon/OAS/RNase L-mediated
            cellular destruction by interacting with OAS1A during oogenesis and
            early embryonic development.
REFERENCE   5  (bases 1 to 1750)
  AUTHORS   Mashimo,T., Glaser,P., Lucas,M., Simon-Chazottes,D., Ceccaldi,P.E.,
            Montagutelli,X., Despres,P. and Guenet,J.L.
  TITLE     Structural and functional genomics and evolutionary relationships
            in the cluster of genes encoding murine 2',5'-oligoadenylate
            synthetases
  JOURNAL   Genomics 82 (5), 537-552 (2003)
   PUBMED   14559211
REFERENCE   6  (bases 1 to 1750)
  AUTHORS   Kakuta,S., Shibata,S. and Iwakura,Y.
  TITLE     Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene
            family
  JOURNAL   J Interferon Cytokine Res 22 (9), 981-993 (2002)
   PUBMED   12396720
REFERENCE   7  (bases 1 to 1750)
  AUTHORS   Perelygin,A.A., Scherbik,S.V., Zhulin,I.B., Stockman,B.M., Li,Y.
            and Brinton,M.A.
  TITLE     Positional cloning of the murine flavivirus resistance gene
  JOURNAL   Proc Natl Acad Sci U S A 99 (14), 9322-9327 (2002)
   PUBMED   12080145
REFERENCE   8  (bases 1 to 1750)
  AUTHORS   Eskildsen,S., Hartmann,R., Kjeldgaard,N.O. and Justesen,J.
  TITLE     Gene structure of the murine 2'-5'-oligoadenylate synthetase family
  JOURNAL   Cell Mol Life Sci 59 (7), 1212-1222 (2002)
   PUBMED   12222967
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV659301.1 and AK135783.1.
            
            On Sep 19, 2009 this sequence version replaced NM_133893.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052835.1, AB067532.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-629               DV659301.1         1-629
            630-1750            AK135783.1         144-1264
FEATURES             Location/Qualifiers
     source          1..1750
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 60.87 cM"
     gene            1..1750
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /note="2'-5' oligoadenylate synthetase 1D"
                     /db_xref="GeneID:100535"
                     /db_xref="MGI:MGI:2140770"
     exon            1..249
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1152
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /note="2',5'-oligoadenylate synthetase-like 8;
                     2'-5'olygoadenylate synthetase 1D"
                     /codon_start=1
                     /product="inactive 2'-5'-oligoadenylate synthase 1D"
                     /protein_id="NP_598654.1"
                     /db_xref="CCDS:CCDS19631.1"
                     /db_xref="GeneID:100535"
                     /db_xref="MGI:MGI:2140770"
                     /translation="MARELFRTPIWRLDKFIEDQLLPDTTFLTELRADIDSISAFLME
                     RCFQGAAHPVRVSRVVMGGCYNEYTVLKGRSEANMVVFLINLTSFEDQFNGQVVFIEE
                     IWRHLLQLQQEKLCKLKFEVQSPKEPNSRFLSFKLSCPERQHELEFDVQPAYDALYEV
                     RHFKPFDSSNYNKVYAQLTHECTTLEKEGEFSICFTDLHQSFLRYRAPKLWNLIRLVK
                     HWYQLCKEKLRGPLPPQYALELLTVYVWEYGIHENPGLHTAQCFRTVLELVTKYKRLR
                     IYWTWCYDFQHEISDYLQGQIKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQIWID
                     STFFTNHDMSIVEAWEVMPERQECVFL"
     exon            250..538
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     exon            539..735
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     exon            736..968
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1122
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1735
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1710..1715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /note="hexamer: ATTAAA"
     polyA_site      1735
                     /gene="Oas1d"
                     /gene_synonym="oasl8"
                     /note="major polyA site"
ORIGIN      
        1 tatggatata aggggcagct gactcctgag gtaaggctgc agtcagcaaa cactcctggc
       61 ctcaggatgg cgagggaact cttcagaacc ccaatctgga ggctggataa gttcatagag
      121 gatcaactcc ttcctgacac caccttcctt actgagctca gagcagacat cgactccata
      181 agtgctttcc tgatggagag atgcttccaa ggtgccgccc atcctgtgag ggtctccagg
      241 gttgtgatgg gtggctgcta caatgaatac actgtgctca agggcaggtc tgaggccaac
      301 atggtggtgt tccttatcaa tctcacaagc tttgaggatc agttcaacgg acaggtagtg
      361 ttcattgagg aaatttggag acacctactc cagttgcagc aagagaaact atgtaaactc
      421 aagtttgagg tccagagccc aaaggagccc aactccaggt ttctgagctt caagctgagc
      481 tgccccgagc gccagcatga gttggaattt gatgtgcagc cagcctatga tgccctgtat
      541 gaagtaagac acttcaagcc ctttgactcc agtaactaca acaaagtcta cgcccaactc
      601 acccatgagt gcaccacact ggagaaggag ggcgagttct ccatctgctt caccgacctc
      661 catcagagct tcctgaggta tcgtgcgccc aagctctgga acctcatccg tttggtcaag
      721 cactggtatc aactgtgtaa ggagaagctg agggggccgc tgcctccaca gtacgccctg
      781 gagctgctca cagtctacgt ctgggaatac gggatccacg aaaaccctgg actccataca
      841 gcccagtgct tccgcactgt cttagaactt gtcaccaagt acaaacggct tcgaatctac
      901 tggacatggt gttatgactt tcaacacgag atctctgact acctgcaggg acagatcaaa
      961 aaagccaggc ctctgatcct ggatccagca gacccaacaa ggaatgtggc tggttcagac
     1021 ttacaggcat gggacctgct ggcaaaggag gctcagatct ggatagattc gactttcttt
     1081 acgaaccatg atatgtccat tgtggaagcc tgggaagtga tgccagagag acaagaatgt
     1141 gtcttcctgt gagcaccccc agcatctgcc taggagactc cagagtcagg ggcatgtcct
     1201 cctcttctgt aagaccttga cctagagagg acagacagga tggcactcaa ggctccagcg
     1261 aggggcatcc aacctgtgat cagactccag gcttctgatc cctgcctgcc catggacagc
     1321 cttcctcaca ggctgcttcg tctgccttag cttccaacag tgttctctgg gagtcagact
     1381 gtgatggaca gagaagaacg caagctcgac ttccatctgt tcacctgttg ggaggttatg
     1441 tccaatagtg gctgatcatc atcaacaaac cacagcaagc catgaggggg ggtgcactct
     1501 gagggaggag tcctcagacc acacagaaac ttttcagcag tgcatgtggc cctggagccc
     1561 tgggaatctg gccagtgttc atcaaggtgc actgtttctg caacatgcag gctgggttta
     1621 tggtagtgca ggaaaataaa attgcatgca ttttaaaatt tatgatttta aaacttaggg
     1681 gtgtgtgtgt atgagatttg aagcactaaa ttaaagcaaa acgcattgaa ttaaaaaaaa
     1741 aaaaaaaaaa
//
