LOCUS       NM_178644               2388 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus out at first homolog (Oaf), mRNA.
ACCESSION   NM_178644
VERSION     NM_178644.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2388)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2388)
  AUTHORS   Welch,C.L., Xia,Y.R., Shechter,I., Farese,R., Mehrabian,M.,
            Mehdizadeh,S., Warden,C.H. and Lusis,A.J.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   4  (bases 1 to 2388)
  AUTHORS   Xia,Y., Welch,C.L., Warden,C.H., Lange,E., Fukao,T., Lusis,A.J. and
            Gatti,R.A.
  TITLE     Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse
            chromosome 9
  JOURNAL   Mamm Genome 7 (7), 554-555 (1996)
   PUBMED   8672141
REFERENCE   5  (bases 1 to 2388)
  AUTHORS   Boring,L., Gosling,J., Monteclaro,F.S., Lusis,A.J., Tsou,C.L. and
            Charo,I.F.
  TITLE     Molecular cloning and functional expression of murine JE (monocyte
            chemoattractant protein 1) and murine macrophage inflammatory
            protein 1alpha receptors: evidence for two closely linked C-C
            chemokine receptors on chromosome 9
  JOURNAL   J Biol Chem 271 (13), 7551-7558 (1996)
   PUBMED   8631787
REFERENCE   6  (bases 1 to 2388)
  AUTHORS   Warden,C.H., Mehrabian,M., He,K.Y., Yoon,M.Y., Diep,A., Xia,Y.R.,
            Wen,P.Z., Svenson,K.L., Sparkes,R.S. and Lusis,A.J.
  TITLE     Linkage mapping of 40 randomly isolated liver cDNA clones in the
            mouse
  JOURNAL   Genomics 18 (2), 295-307 (1993)
   PUBMED   8288233
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC173346.1.
            
            On Nov 17, 2006 this sequence version replaced NM_178644.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK051349.1, BC028824.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-510               AC173346.1         205775-206284       c
            511-645             AC173346.1         191344-191478       c
            646-826             AC173346.1         190365-190545       c
            827-2388            AC173346.1         187746-189307       c
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 24.24 cM"
     gene            1..2388
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /note="out at first homolog"
                     /db_xref="GeneID:102644"
                     /db_xref="MGI:MGI:94852"
     exon            1..510
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..1092
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /note="out at first protein homolog; OAF homolog"
                     /codon_start=1
                     /product="out at first protein homolog precursor"
                     /protein_id="NP_848759.1"
                     /db_xref="CCDS:CCDS23091.1"
                     /db_xref="GeneID:102644"
                     /db_xref="MGI:MGI:94852"
                     /translation="MRPPGCRDVPSARPALPLLLLLLSPLLLGALHGVGAGSGAPAEL
                     RVRVRLPDSQVIEESLQADSDADSISLDLRKPDGTLISFIADFKKDVKIFRALILGEL
                     EKGQSQFQALCFVTRLHHNDIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNF
                     SQGGLLSPHLHNVCAEATDAIYTRQEDVQFWTERGVDSSVFEALPKALEQAELPRCGR
                     VGDRGKPCTCHYSLSLAWYPCMLKYCHSRDRPAPYKCGIRSCRKSYTFDFYVPQKQLC
                     LWDEDP"
     exon            511..645
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            646..826
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /inference="alignment:Splign:2.1.0"
     exon            827..2388
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1737..1742
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /note="hexamer: AATAAA"
     polyA_site      1763
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /note="major polyA site"
     regulatory      2101..2106
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
                     /note="hexamer: ATTAAA"
     polyA_site      2124
                     /gene="Oaf"
                     /gene_synonym="D130038B21Rik; D9Ucla1"
ORIGIN      
        1 ggagtccgga gctcaggaat cggggcggct aggggacacg cacggggggc gccgtccggg
       61 actcggggtg cgtggctgta cgcggcccac gtgaattcgc tgcacgtcgt ggggaacctc
      121 cgggttgagt ctcccctcta gaagtagggg actgccggga atccccgaac cggaccccca
      181 acttcgagca aactttgtag gcgcgtctcc cctcccccac gcggcgcgcc gggggccccg
      241 gggatgcggc cccctggctg ccgcgacgtc ccctcggcgc gccccgcgct gccgctgctg
      301 ctgctgctgc tgtcgccgct gctgcttggg gcgctgcacg gcgtgggcgc gggcagcggc
      361 gctccggccg agctgcgggt ccgagtgaga ctgcccgaca gccaggtgat cgaggagagt
      421 ctacaggcgg acagcgacgc ggacagcatc agccttgatc tgcgcaaacc cgacggcact
      481 ctcatctcct tcatcgcgga tttcaagaag gacgtgaaga tcttccgagc cctgatcctc
      541 ggggagctgg agaaggggca gagtcagttc caggcacttt gctttgtcac aaggctgcac
      601 cacaatgaca tcatccccag tgaggccatg gccaagctcc ggcagaaaaa cccccgcgca
      661 gtgcggcagg ctgaggaagt gaggggtctg gaacagttac atatggatat cgctgttaac
      721 ttcagccagg ggggcctgct gagtccccat ctccacaacg tatgtgctga ggccacagat
      781 gccatctaca cccgccagga ggatgtccag ttctggacag agcgaggtgt ggacagttct
      841 gttttcgagg ctctgcccaa ggcattagaa caggcggaat tacctcgttg tggacgagtt
      901 ggggatcgag gaaagccctg tacttgccac tacagtctga gcctggcctg gtacccatgc
      961 atgctcaagt attgccacag tcgtgatcgg ccagcgccct acaagtgtgg catccgaagc
     1021 tgcaggaaaa gctacacctt tgacttctat gtacctcaga agcaactgtg cctctgggat
     1081 gaggacccct aacaacagga gacagaggac caagaacgga tacttgggcc tgcaaattct
     1141 tcgctgacca ccagagagcg tggcaaccca atcaggtctt aggtctcttc ctgagccgct
     1201 ggccctgaag ccacaacctc atctgcatga ctgtgaaagg gtgtcaccgc aaccttgagg
     1261 cagccctgat gcccacctgt gcccatcttg aggcattggg gggtgggggg gggaggcagt
     1321 tctccagacg gataccctcc cctcttcctt tcacctgaaa tgtcccgcga aggtggaatc
     1381 aaaatgcacc ggcctaggcc tttatggaac ttgttccgga ggcatggccc tgtagcacac
     1441 tatctcacca gcaagggaac cagagaggga cagctgggga ctcgtgcccc agctcctgtg
     1501 tctggttaca gtgccttctc tctaccctgg gggcaacggg gagtagggat gctgcctcca
     1561 agaccaccgc gtgtgccttt cctgagaccc aatttggata cttcagcggg caccgattct
     1621 tcctgcccct ggactgatgt actttggtca ggttctgggg cagggaggga gcatgaagta
     1681 caaggaaaac ttgaattcca gatttttaat gcaaaatatt tatcatttgt accagaaata
     1741 aaagtctttt aagttttcac tcaccctatg gcgccagctt aggctttcgg agagaacttt
     1801 gtcccgtgct gccacctagt gtcagaaatg tgccttacat ggttagtgcc agtctgggca
     1861 aagcaacttc taaaggtcct attgtgtgat ctgtgagagg ctctgtgctt aagatgatgg
     1921 aacaagggag ctgggaagga ctcagtagtt aagagcacgt gctgcttttt tacagaggac
     1981 ccaagttcga ttccttacat ccgcttccag tgtggggagt gtcacggaca cctgtaacat
     2041 caacataatg gagatcggcc accttttatg gcctccaagt gctctaacac atataataaa
     2101 attaaattaa tttaaaatta aaaactaggg acttcaggat ggctcagtga ttaagaacac
     2161 tggctgctct tccagagatc ccatgttcca tgctcaagac ccacatggta aatctgatgc
     2221 cctcttctgg cttgcaagag accttgtacg tggagctcat acatgcaagc aaaacaccag
     2281 tggaaacaca agtaagttat ataaatgatg aggcaaggac cgaagacata gctcatttat
     2341 agcgaatttg ctcaggatgg gcaaggccat ggtcctaatg tcctgcac
//
