LOCUS       NM_172782               2492 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus nuclear transport factor 2-like export factor 2
            (Nxt2), transcript variant 1, mRNA.
ACCESSION   NM_172782
VERSION     NM_172782.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Hu,J., Wang,H., He,D., Yang,R., Yang,D., Li,D., Wei,S., Fan,X.,
            Mao,X., Lyu,Y. and Li,Y.
  TITLE     Genetic characterization of nuclear export factor NXT1 and its
            paralog NXT2 in primates and murine rodents
  JOURNAL   Zoology (Jena) 151, 126002 (2022)
   PUBMED   35219094
  REMARK    GeneRIF: Genetic characterization of nuclear export factor NXT1 and
            its paralog NXT2 in primates and murine rodents.
REFERENCE   2  (bases 1 to 2492)
  AUTHORS   Khan,M., Jabeen,N., Khan,T., Hussain,H.M.J., Ali,A., Khan,R.,
            Jiang,L., Li,T., Tao,Q., Zhang,X., Yin,H., Yu,C., Jiang,X. and
            Shi,Q.
  TITLE     The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2
            are dispensable for fertility in mice
  JOURNAL   Sci Rep 8 (1), 4975 (2018)
   PUBMED   29563520
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2492)
  AUTHORS   Lai,D., Sakkas,D. and Huang,Y.
  TITLE     The fragile X mental retardation protein interacts with a distinct
            mRNA nuclear export factor NXF2
  JOURNAL   RNA 12 (8), 1446-1449 (2006)
   PUBMED   16790844
REFERENCE   4  (bases 1 to 2492)
  AUTHORS   Sasaki,M., Takeda,E., Takano,K., Yomogida,K., Katahira,J. and
            Yoneda,Y.
  TITLE     Molecular cloning and functional characterization of mouse Nxf
            family gene products
  JOURNAL   Genomics 85 (5), 641-653 (2005)
   PUBMED   15820316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB851047.1, BC068166.1 and BB038253.1.
            
            On Mar 14, 2014 this sequence version replaced NM_172782.3.
            
            Transcript Variant: This variant (1) encodes isoform a. Variants 1
            and 2 encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144349.1, BC064727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                BB851047.1         2-48
            48-2484             BC068166.1         1-2437
            2485-2492           BB038253.1         274-281
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 63.02 cM"
     gene            1..2492
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /note="nuclear transport factor 2-like export factor 2"
                     /db_xref="GeneID:237082"
                     /db_xref="MGI:MGI:2147914"
     exon            1..205
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..619
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /note="isoform a is encoded by transcript variant 1;
                     NTF2-related export protein 2"
                     /codon_start=1
                     /product="NTF2-related export protein 2 isoform a"
                     /protein_id="NP_766370.2"
                     /db_xref="CCDS:CCDS41155.1"
                     /db_xref="GeneID:237082"
                     /db_xref="MGI:MGI:2147914"
                     /translation="MALAVNFKTYVDQACRAAEEFVNIYYETMDKRRHALVRLYLDKA
                     TLIWNGNVVTGLEALANFFEMLPSSEFQINMLDCQPVHEQATQCQTTVLVVTSGVVKF
                     DGNKQHFFNQNFLLTAQSTPNSTVWKIASDCFRFQDWASI"
     exon            206..292
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            293..437
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /inference="alignment:Splign:2.1.0"
     exon            438..2492
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2458..2463
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /note="hexamer: AATAAA"
     regulatory      2463..2468
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /note="hexamer: AATAAA"
     polyA_site      2481
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
     polyA_site      2484
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /note="major polyA site"
ORIGIN      
        1 atcggggtga ttttaacacc ggactgagct acttccgggg gacaatgggc gggttgagaa
       61 atctgtgcca ttggcgaggt tcgttttgtt gctaaacatc tcatccttcc acagccaaag
      121 gacccagacg agcgcggaag tgcggacatc tccggggcca gctctggagc agaccatttc
      181 cagccccctg atggccttgg cagtgaattt taaaacttat gtggatcagg catgtagagc
      241 tgccgaggaa tttgtcaata tttactatga gacaatggac aaaagacgac atgcacttgt
      301 caggctgtat ttggacaaag ccactctaat ctggaatgga aatgttgtta cagggctgga
      361 agcccttgct aatttttttg agatgttgcc ttccagcgaa ttccagatca atatgttaga
      421 ttgccaacca gttcatgagc aagctaccca gtgccaaact acagtgctcg ttgtgaccag
      481 tggagttgtg aagtttgatg gaaacaagca gcacttcttt aaccagaact tcctgctgac
      541 tgcgcagagc actcctaaca gcactgtgtg gaagattgca agtgattgct tccgttttca
      601 agattgggct agtatttaaa ggagcaaaaa cccactctat tggtccatta gttccagcaa
      661 gagaagttag aggagaatta atatatttcg tgcaaaagta ctacaaactt aagtgtatgt
      721 gctaaaacta aatgtatgta acattttttt tttagcagcg cctttgctag atcagctgcc
      781 agtttggatt attgccctta agagctttaa agatagtttt ttttacatgc cttatgcata
      841 cattccacta ctgacactct caaggtaata ttaaacatga tctaggtact aagatattca
      901 ctgtgaaccc gatctattgc acaaatggag tccttttgta ttactctcta tgggatagca
      961 caagatagct ctgtaggata gtctcagtta ctagggtaat ttctcaatga agcacatgcc
     1021 tgtttacgat taacactaaa gttttaatat ataagtattt gaagtctgtt caacttagtt
     1081 ttacgctagt gttctgacat attttaattg catataactg tataatagtc cgtgttgttt
     1141 tcttgcattg acatgtttcc ttttgaaatg aggtaatcaa ttaggtgggg aaaaaaatgt
     1201 tctcgactga tacttgtata tcgggtgcat ttaatggcag tcacaactct gaaacctttt
     1261 gttcgtgccg gcttcaggtc aatgtgttta tgtgataaat gggagtgata acagaagctt
     1321 taatgggaga gtaagaaatg agaaacatag aaatctaagg ctgaagccaa caccaaaaga
     1381 gggagcacac ctgttcccta cctcctggaa gtggagccaa gtttcaggat ttgcatccca
     1441 agagtctcta agaattcttg ccatggtcct aaaaactgga ttttaagatt attttacttc
     1501 cccttcatgc ctgtctccag tatccacccc agcttctttc tgaatgtaag ggattaagat
     1561 atcagctgta aacttaactt tgtctccgaa tctgagaatt cgaaagaaag ctatgctcag
     1621 tctctgtaca tgctgaactc caaattcttc catatcaact tcaagcccca agcctccaat
     1681 gtattaccta ccatgcgcat gaataatttt cttccatggc ttttacactg tcaacggctt
     1741 tacctacttt ttaaaattaa gtctttgatt ttatgattta tttctgtatg gcactggata
     1801 aaaatattat taaaacattt ctgcctatgg ttaaaaatcc agaaatcaaa gaaatgatct
     1861 tcatgataaa cttcaaagga acaaacttta tgttttagct tctaaagaca aaaatatagt
     1921 gtttttagct tttagttaaa ctttataatt ctttgcaatt tttaagtatt ttaaactaaa
     1981 tatgcaaggt ttgttctata ttatgatcac tattaatctt ttatcactca attttaaaac
     2041 tagtaattta ctttggctca gaaatgtact atatttataa ttattgtatt atttaaatta
     2101 aatagaaggt gatagaactg atatttaaaa ccatggctca tttaagttct tatcaaaaca
     2161 tatacattct agtctattca gagtgagctt gctcttattt tgaatttttt ccattaacta
     2221 tatctttagc aaaaataatt aaaatgccca gtcactgccc tttctattgg tggagaacaa
     2281 tcgcaaaatc tgtgtataat tagcaataac agaactaaac cattgtttag ttgctaatca
     2341 tatgttgctt tatccatatg ctgtatgact ccataacatg tatgacttta aatggctgga
     2401 actgctcata tgtggactaa actatttttg acatgttcat atttttataa cttaagaaat
     2461 aaaataaaag ctgcattttc acaagttttc tc
//
