LOCUS       NP_766370                142 aa            linear   ROD 27-APR-2025
DEFINITION  NTF2-related export protein 2 isoform a [Mus musculus].
ACCESSION   NP_766370
VERSION     NP_766370.2
DBSOURCE    REFSEQ: accession NM_172782.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 142)
  AUTHORS   Hu,J., Wang,H., He,D., Yang,R., Yang,D., Li,D., Wei,S., Fan,X.,
            Mao,X., Lyu,Y. and Li,Y.
  TITLE     Genetic characterization of nuclear export factor NXT1 and its
            paralog NXT2 in primates and murine rodents
  JOURNAL   Zoology (Jena) 151, 126002 (2022)
   PUBMED   35219094
  REMARK    GeneRIF: Genetic characterization of nuclear export factor NXT1 and
            its paralog NXT2 in primates and murine rodents.
REFERENCE   2  (residues 1 to 142)
  AUTHORS   Khan,M., Jabeen,N., Khan,T., Hussain,H.M.J., Ali,A., Khan,R.,
            Jiang,L., Li,T., Tao,Q., Zhang,X., Yin,H., Yu,C., Jiang,X. and
            Shi,Q.
  TITLE     The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2
            are dispensable for fertility in mice
  JOURNAL   Sci Rep 8 (1), 4975 (2018)
   PUBMED   29563520
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 142)
  AUTHORS   Lai,D., Sakkas,D. and Huang,Y.
  TITLE     The fragile X mental retardation protein interacts with a distinct
            mRNA nuclear export factor NXF2
  JOURNAL   RNA 12 (8), 1446-1449 (2006)
   PUBMED   16790844
REFERENCE   4  (residues 1 to 142)
  AUTHORS   Sasaki,M., Takeda,E., Takano,K., Yomogida,K., Katahira,J. and
            Yoneda,Y.
  TITLE     Molecular cloning and functional characterization of mouse Nxf
            family gene products
  JOURNAL   Genomics 85 (5), 641-653 (2005)
   PUBMED   15820316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB851047.1, BC068166.1 and BB038253.1.
            
            On May 30, 2009 this sequence version replaced NP_766370.1.
            
            Transcript Variant: This variant (1) encodes isoform a. Variants 1
            and 2 encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144349.1, BC064727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..142
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 63.02 cM"
     Protein         1..142
                     /product="NTF2-related export protein 2 isoform a"
                     /note="NTF2-related export protein 2"
                     /calculated_mol_wt=16125
     Region          13..138
                     /region_name="NTF2"
                     /note="Nuclear transport factor 2 (NTF2) domain plays an
                     important role in the trafficking of macromolecules, ions
                     and small molecules between the cytoplasm and nucleus.
                     This bi-directional transport of macromolecules across the
                     nuclear envelope requires many...; cd00780"
                     /db_xref="CDD:238403"
     Site            order(41,47,54,77,79..80,95,121,131..133,135,137)
                     /site_type="active"
                     /note="TAP/p15 interaction [active]"
                     /db_xref="CDD:238403"
     Site            order(45,47..48,74..75,77,79..80,93,97..99,103,105..108,
                     111,121,131..133,135..138)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238403"
     Site            order(48..49,66,69,98,100,102..103,105,108,134,136,138)
                     /site_type="active"
                     /note="RanGDP-NTF2 interaction [active]"
                     /db_xref="CDD:238403"
     CDS             1..142
                     /gene="Nxt2"
                     /gene_synonym="6330587F24Rik; P15-2"
                     /coded_by="NM_172782.4:191..619"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS41155.1"
                     /db_xref="GeneID:237082"
                     /db_xref="MGI:MGI:2147914"
ORIGIN      
        1 malavnfkty vdqacraaee fvniyyetmd krrhalvrly ldkatliwng nvvtgleala
       61 nffemlpsse fqinmldcqp vheqatqcqt tvlvvtsgvv kfdgnkqhff nqnflltaqs
      121 tpnstvwkia sdcfrfqdwa si
//
