LOCUS       NM_019761                969 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus NTF2-related export protein 1 (Nxt1), transcript
            variant 2, mRNA.
ACCESSION   NM_019761
VERSION     NM_019761.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 969)
  AUTHORS   Xin,Y., He,Q., Liang,H., Zhang,K., Guo,J., Zhong,Q., Chen,D.,
            Li,J., Liu,Y. and Chen,S.
  TITLE     m6A epitranscriptomic modification regulates neural
            progenitor-to-glial cell transition in the retina
  JOURNAL   Elife 11, e79994 (2022)
   PUBMED   36459087
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 969)
  AUTHORS   Hu,J., Wang,H., He,D., Yang,R., Yang,D., Li,D., Wei,S., Fan,X.,
            Mao,X., Lyu,Y. and Li,Y.
  TITLE     Genetic characterization of nuclear export factor NXT1 and its
            paralog NXT2 in primates and murine rodents
  JOURNAL   Zoology (Jena) 151, 126002 (2022)
   PUBMED   35219094
  REMARK    GeneRIF: Genetic characterization of nuclear export factor NXT1 and
            its paralog NXT2 in primates and murine rodents.
REFERENCE   3  (bases 1 to 969)
  AUTHORS   Skinner,S.J., Deleault,K.M., Fecteau,R. and Brooks,S.A.
  TITLE     Extracellular signal-regulated kinase regulation of tumor necrosis
            factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1
            binding and the AU-rich element
  JOURNAL   J Biol Chem 283 (6), 3191-3199 (2008)
   PUBMED   18048358
  REMARK    GeneRIF: regulation of tumor necrosis factor-alpha mRNA
            nucleocytoplasmic transport by ERK map kinases requires TAP-NxT1
            binding and the AU-rich element
REFERENCE   4  (bases 1 to 969)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   5  (bases 1 to 969)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 969)
  AUTHORS   Sasaki,M., Takeda,E., Takano,K., Yomogida,K., Katahira,J. and
            Yoneda,Y.
  TITLE     Molecular cloning and functional characterization of mouse Nxf
            family gene products
  JOURNAL   Genomics 85 (5), 641-653 (2005)
   PUBMED   15820316
REFERENCE   7  (bases 1 to 969)
  AUTHORS   Levesque,L., Guzik,B., Guan,T., Coyle,J., Black,B.E., Rekosh,D.,
            Hammarskjold,M.L. and Paschal,B.M.
  TITLE     RNA export mediated by tap involves NXT1-dependent interactions
            with the nuclear pore complex
  JOURNAL   J Biol Chem 276 (48), 44953-44962 (2001)
   PUBMED   11579093
REFERENCE   8  (bases 1 to 969)
  AUTHORS   Black,B.E., Levesque,L., Holaska,J.M., Wood,T.C. and Paschal,B.M.
  TITLE     Identification of an NTF2-related factor that binds Ran-GTP and
            regulates nuclear protein export
  JOURNAL   Mol Cell Biol 19 (12), 8616-8624 (1999)
   PUBMED   10567585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928638.7, AK003254.1, CJ186513.1 and AW908959.1.
            
            On Oct 27, 2007 this sequence version replaced NM_019761.5.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same isoform.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC023672.1, AK003254.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AL928638.7         73092-73118
            28-119              AK003254.1         3-94
            120-447             CJ186513.1         109-436
            448-969             AW908959.1         1-522               c
FEATURES             Location/Qualifiers
     source          1..969
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 73.53 cM"
     gene            1..969
                     /gene="Nxt1"
                     /gene_synonym="1110001N02Rik"
                     /note="NTF2-related export protein 1"
                     /db_xref="GeneID:56488"
                     /db_xref="MGI:MGI:1929619"
     exon            1..221
                     /gene="Nxt1"
                     /gene_synonym="1110001N02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            222..966
                     /gene="Nxt1"
                     /gene_synonym="1110001N02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..703
                     /gene="Nxt1"
                     /gene_synonym="1110001N02Rik"
                     /codon_start=1
                     /product="NTF2-related export protein 1"
                     /protein_id="NP_062735.4"
                     /db_xref="CCDS:CCDS16840.1"
                     /db_xref="GeneID:56488"
                     /db_xref="MGI:MGI:1929619"
                     /translation="MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTAT
                     LVWNGNAVSGQESLSEFFEMLPSSEFQISVVDCQPVHDDATPSQTTVLVVICGTVKFE
                     GNKQRDFNQNFILTAQASPSNTVWKIASDCFRFQDWAS"
ORIGIN      
        1 gacgggaacc gggatgctag cgcctgcgca cattgcagct tgcggcgcgc gggaagccac
       61 taccggcgct taaccgttcc tcgcctcctg gacgtcggct tctcaggcgg agcctctggg
      121 aggaagagga gaacaggaga gaaactcttc tggcccggga ccgcgaccgg ggcggaaccc
      181 gggaccgagt cgccttggcg gcgctgaccg agatcgagca gtccctggat ccctaaggag
      241 gaggcgctca ggcggaggcc tcttgtcagc agaaccagag atggcatcag tagatttcaa
      301 gacctatgtg gaccaggcct gcagagctgc agaggaattt gtcaatgtct attacacgac
      361 tatggataag cggcgtcggc tgctgtcccg cctgtacatg ggcacagcca ctttagtatg
      421 gaatggaaat gctgtttcag gacaagaatc cttgagtgag ttttttgaga tgttgccttc
      481 cagtgagttc caaatcagcg tggtagactg ccagcctgtc catgatgacg ctacaccaag
      541 ccagaccacc gtgcttgtgg tcatctgtgg aacagtgaag tttgaaggca acaaacagcg
      601 ggacttcaac cagaacttca tcttgactgc tcaggcgtca cccagtaaca cggtgtggaa
      661 gatagcaagt gactgcttcc ggttccagga ctgggccagc tagtgggggt gaccgaggca
      721 tcttagctta agcccagctc tgcagagaaa tgccagtctc aaatctcagg atgtggagaa
      781 cacaagttca tttttgttgt cacagcagca ctgcagactg gatgttggac tcccagaatc
      841 cccttcctgg ttatatactg gtttgtcata gttgcctttt aaaagtagta aactttctat
      901 ttttctactt actcagtaga gaccctgttt ctggaacttg acaaataaat atgttgcttt
      961 tctgccaaa
//
