LOCUS       NM_172921               3173 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus neurexophilin and PC-esterase domain family, member 4
            (Nxpe4), mRNA.
ACCESSION   NM_172921
VERSION     NM_172921.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3173)
  AUTHORS   Tabakoff B, Saba L, Kechris K, Hu W, Bhave SV, Finn DA, Grahame NJ
            and Hoffman PL.
  TITLE     The genomic determinants of alcohol preference in mice
  JOURNAL   Mamm Genome 19 (5), 352-365 (2008)
   PUBMED   18563486
REFERENCE   2  (bases 1 to 3173)
  AUTHORS   Saba L, Bhave SV, Grahame N, Bice P, Lapadat R, Belknap J, Hoffman
            PL and Tabakoff B.
  TITLE     Candidate genes and their regulatory elements: alcohol preference
            and tolerance
  JOURNAL   Mamm Genome 17 (6), 669-688 (2006)
   PUBMED   16783646
REFERENCE   3  (bases 1 to 3173)
  AUTHORS   Yaguchi H, Togawa K, Moritani M and Itakura M.
  TITLE     Identification of candidate genes in the type 2 diabetes modifier
            locus using expression QTL
  JOURNAL   Genomics 85 (5), 591-599 (2005)
   PUBMED   15820311
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154373.2 and AC160992.2.
            
            On Apr 12, 2011 this sequence version replaced NM_172921.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.183729.1,
                                           SRR7974084.1606.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               AC154373.2         3636-3770           c
            136-330             AC160992.2         10069-10263
            331-473             AC160992.2         23068-23210
            474-576             AC160992.2         23589-23691
            577-679             AC160992.2         24446-24548
            680-1413            AC160992.2         26904-27637
            1414-1475           AC160992.2         28335-28396
            1476-1682           AC160992.2         30683-30889
            1683-3173           AC160992.2         32731-34221
FEATURES             Location/Qualifiers
     source          1..3173
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 26.39 cM"
     gene            1..3173
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /note="neurexophilin and PC-esterase domain family, member
                     4"
                     /db_xref="GeneID:244853"
                     /db_xref="MGI:MGI:1924792"
     exon            1..135
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            136..330
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            331..473
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            474..576
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            577..679
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     CDS             587..2218
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /note="protein FAM55D; family with sequence similarity 55,
                     member D"
                     /codon_start=1
                     /product="NXPE family member 4"
                     /protein_id="NP_766509.2"
                     /db_xref="CCDS:CCDS23152.1"
                     /db_xref="GeneID:244853"
                     /db_xref="MGI:MGI:1924792"
                     /translation="MKTLASRKSLWMLLFIVIFWVSFTVFRNPVKLRTMFKLPVSFNR
                     WNLVMGPSCPAVPLNLPVSPKETELRIREVLEKLDKQIPPRPFTHLNYTTSATHSTAT
                     ILNPRDTHCVGDQLDILVEARDHLGNRKGYGGDFMRARMFSPALKAGASGKVTDFNNG
                     TYLVSFTLFWEGTVSLSILLMHPSEGVSALWRSRKQGYDRIIFSGQFVSGASQVHTEC
                     ALVLNSSVELCQYLDAQDQEAFYCVKPPNVPCAALTYMQSKNKDVSYLSQQERSLFER
                     SNIAVEIMEKSNAISVSKCNTDTAPVKEKCKLGMVSAIPSGHVWKNAWTPASCSLAPI
                     KMKDCLRGKFIYLMGDSTIRQWMEYFKSKVNTLRSVDLHESGKLQHQLAVDLDEKISI
                     QWQKHGYPLIGSLVYSVKEIENIARIIDRTGGEKNTVIVISLGQHFRPFPIDLFIRRA
                     LNVHKALQRLLLRSPDTVVVLKTENTRELNSDVERFSDFHGYTQYLALKDIFQDLNVG
                     VIDAWDMTVAYGINNVHPPEDVVRSQINIFLNYIC"
     exon            680..1413
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1475
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1682
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..3173
                     /gene="Nxpe4"
                     /gene_synonym="C130036J11; D930028F11Rik; Fam55d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attggatcac attattcagg acaacctgac tctgcctccc tgggtcacca ccattccgaa
       61 ttggctccag catacacgct ctcaggttcc ctttgaagtg agagatggtt tcactggaca
      121 gctagcagca ctcggatgag aaaacctgac acttggcaat caatcaggtg aggagccaac
      181 acaaatccac agcaccatga gcttccatgg cactgtcctg aaatgcgtgt cctaacaaag
      241 tgtccttggt ctggatgtca tctgcctcac tggaacgtgt taggtaggat ctgaccagga
      301 actctcacct tgccgaggaa acctgctatg gccccacaag accaactgct gtttcctatg
      361 ggccctatgc atgtgtctga agcacctacc tgctcttcct gggactctat cagaacaaga
      421 acacaaatcc aattgctttg gaacatgtga ctccgtcctc cgcttggtct gaggaaagct
      481 gtacactggc agcactgccc tggccacaga agcaggctct ccaccaagct catccagttt
      541 cttgaaatga gaccaaaacg agcctttaga ttaaaggatt tgaaccatga aaacgctggc
      601 cagtcgtaag tcactgtgga tgctgctttt tatagtcatc ttctgggtct cttttacagt
      661 tttcagaaac cctgtgaagc tacggaccat gttcaagttg cctgtgtcct tcaatcgctg
      721 gaacttggtc atgggaccct catgccctgc agtgcctctg aacctaccag tttcaccaaa
      781 agagacagaa ctgagaatca gggaggtcct ggagaaacta gacaaacaga tccctcccag
      841 acccttcacc cacctcaact acaccacaag cgccacacac agtacagcca ccatcctcaa
      901 ccctcgggat acacactgtg tgggggacca gctggacatc ctggtagagg ctagagacca
      961 cctaggaaac aggaaggggt atggtgggga cttcatgagg gccaggatgt tctccccagc
     1021 cctgaaggca ggagcttctg gaaaggtgac agacttcaac aatggcactt acctcgtcag
     1081 cttcactctg ttctgggagg gcacggtctc cctgtctatc ctgctcatgc accccagtga
     1141 aggggtgtca gctctctgga gatcaaggaa acagggctac gacagaatca tcttctcagg
     1201 ccagtttgtc agtggtgctt ctcaggtcca cactgaatgt gccctggttc taaattcaag
     1261 tgttgagctg tgccagtatc tggatgccca ggaccaagaa gctttctact gtgtgaagcc
     1321 tccaaatgtg ccctgtgcag ctctcaccta catgcagtca aagaacaagg atgtttccta
     1381 tcttagccaa caagaaagga gcctctttga aaggtcaaat atagctgtgg agattatgga
     1441 aaaatccaat gcgattagtg tctccaaatg caacacagac acagctccag tgaaggagaa
     1501 atgcaagctc gggatggtat ctgcaatccc tagtgggcac gtctggaaaa acgcatggac
     1561 tcctgcctcc tgcagtctgg ctccaatcaa aatgaaagac tgcctgaggg gaaaatttat
     1621 ctatctaatg ggtgattcca caatccgcca gtggatggaa tacttcaaaa gcaaagtcaa
     1681 cacactgagg tccgtggacc tgcatgagag tgggaaactg caacaccaac ttgccgtgga
     1741 cttggatgag aaaatcagca tccagtggca aaaacatggt taccctctta tcgggtcatt
     1801 ggtctactct gtcaaagaaa tagagaacat tgcacggata attgacagaa ctggaggaga
     1861 gaaaaacaca gtcatcgtca tttctctggg ccagcatttc agaccctttc ccattgatct
     1921 ttttatccga agggccctca atgttcacaa agctcttcag cgtcttctcc tgagaagccc
     1981 ggacactgtg gtggtcctca aaacagaaaa caccagggag ttaaacagcg acgtggagag
     2041 gtttagtgac ttccatggtt acacgcagta tcttgcctta aaggatattt tccaggatct
     2101 caatgtgggt gtcattgatg cctgggacat gacagttgca tatggcataa acaatgtcca
     2161 cccaccagag gatgtagtta gaagtcaaat taatatattc ttaaactaca tttgctagca
     2221 aacacataac tttgaaagtc actctttgaa cttaaaagat acagtgactc ctgcagctgt
     2281 gccaagtgcc aggatgcccc agttactcca aggacataat ctgtattatg gtccatatgg
     2341 tccacctact tcatcttaac aaggcattca tacactgccc ttctgctcaa aattgaagcc
     2401 caaaagagtc aatggaaggt ccacattttt ttattagagc cacattgctc tttgccgatt
     2461 ggaagttagg attcctgtgc ctaagacctt ctccttgttg ctgtgagttc agaacaatga
     2521 agtaattttg ataaaattct taaaaggtat ttgattcaat ttgtaaatat tttgttgata
     2581 attttttcat ccatgttaat caagaaaatt gatctgtact ttcttggtca tatctcagag
     2641 tttgacatca ggccattaca gacttcaaaa aaaaaatgac ttgggttgta tttctcctgg
     2701 ttgtaatttg tggaaggttt tgagacgtgt tttgattaga ttttctttaa aagtttcatg
     2761 gtattcagca cttaatctgt ccaggtctgg gctgttttgg agagagactt ttaataactg
     2821 cttcaatctc tttgcttatt acagttctgt ttaaattgtt tctattttct aggtttaact
     2881 ttgataggcc aaatgcattt agaaatttat ctttcttcta ggttttccag cttttttgga
     2941 tataagattt tggataaaca aaaacaaaat atgtccaaaa caccatcttg aaacctgata
     3001 ttttgtacac taattttata acaaataaaa ataaaatttc taaatgaaaa acatattaaa
     3061 ataagaatta ataatgcaaa atattttagt gattttactt tcatatatta aatacaaatt
     3121 tatagtttgc ttttcataag tatattataa attatattct ttatatttcc ttt
//
