LOCUS       NM_001024141            2978 bp    mRNA    linear   ROD 22-APR-2022
DEFINITION  Mus musculus nuclear RNA export factor 3 (Nxf3), mRNA.
ACCESSION   NM_001024141
VERSION     NM_001024141.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2978)
  AUTHORS   Li MW, Sletten AC, Lee J, Pyles KD, Matkovich SJ, Ory DS and
            Schaffer JE.
  TITLE     Nuclear export factor 3 regulates localization of small nucleolar
            RNAs
  JOURNAL   J Biol Chem 292 (49), 20228-20239 (2017)
   PUBMED   29021253
  REMARK    GeneRIF: evidence of a new role for NXF3 in regulating the
            distribution of snoRNAs between the nuclear and cytoplasmic
            compartments.
REFERENCE   2  (bases 1 to 2978)
  AUTHORS   Zhou J, McCarrey JR and Wang PJ.
  TITLE     A 1.1-Mb segmental deletion on the X chromosome causes meiotic
            failure in male mice
  JOURNAL   Biol Reprod 88 (6), 159 (2013)
   PUBMED   23677977
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2978)
  AUTHORS   Yin Y, Wang G, Liang N, Zhang H, Liu Z, Li W and Sun F.
  TITLE     Nuclear export factor 3 is involved in regulating the expression of
            TGF-beta3 in an mRNA export activity-independent manner in mouse
            Sertoli cells
  JOURNAL   Biochem J 452 (1), 67-78 (2013)
   PUBMED   23438076
  REMARK    GeneRIF: Mechanistic insights into the roles of NXF3 are implicated
            in transforming growth factor (TGF)-beta-mediated expression of
            Tgfbeta3 and other genes.
REFERENCE   4  (bases 1 to 2978)
  AUTHORS   Vanmarsenille L, Verbeeck J, Belet S, Roebroek AJ, Van de Putte T,
            Nevelsteen J, Callaerts-Vegh Z, D'Hooge R, Marynen P and Froyen G.
  TITLE     Generation and characterization of an Nxf7 knockout mouse to study
            NXF5 deficiency in a patient with intellectual disability
  JOURNAL   PLoS One 8 (5), e64144 (2013)
   PUBMED   23675524
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2978)
  AUTHORS   Zhou J, Pan J, Eckardt S, Leu NA, McLaughlin KJ and Wang PJ.
  TITLE     Nxf3 is expressed in Sertoli cells, but is dispensable for
            spermatogenesis
  JOURNAL   Mol Reprod Dev 78 (4), 241-249 (2011)
   PUBMED   21308854
  REMARK    GeneRIF: The Nxf3 is expressed exclusively in Sertoli cells of the
            postnatal testis, in a developmentally regulated manner.
REFERENCE   6  (bases 1 to 2978)
  AUTHORS   Sasaki M, Takeda E, Takano K, Yomogida K, Katahira J and Yoneda Y.
  TITLE     Molecular cloning and functional characterization of mouse Nxf
            family gene products
  JOURNAL   Genomics 85 (5), 641-653 (2005)
   PUBMED   15820316
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671914.9.
            
            On Oct 19, 2007 this sequence version replaced NM_001024141.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB178899.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               AL671914.9         156346-156504       c
            160-319             AL671914.9         152213-152372       c
            320-473             AL671914.9         151871-152024       c
            474-557             AL671914.9         150809-150892       c
            558-662             AL671914.9         150610-150714       c
            663-768             AL671914.9         150240-150345       c
            769-857             AL671914.9         150030-150118       c
            858-967             AL671914.9         149445-149554       c
            968-1004            AL671914.9         147985-148021       c
            1005-1073           AL671914.9         147636-147704       c
            1074-1129           AL671914.9         147510-147565       c
            1130-1237           AL671914.9         147257-147364       c
            1238-1296           AL671914.9         147080-147138       c
            1297-1412           AL671914.9         146733-146848       c
            1413-1455           AL671914.9         146584-146626       c
            1456-1528           AL671914.9         145949-146021       c
            1529-1702           AL671914.9         145105-145278       c
            1703-1763           AL671914.9         144671-144731       c
            1764-2978           AL671914.9         143348-144562       c
FEATURES             Location/Qualifiers
     source          1..2978
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 57.38 cM"
     gene            1..2978
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /note="nuclear RNA export factor 3"
                     /db_xref="GeneID:245610"
                     /db_xref="MGI:MGI:2685230"
     exon            1..159
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..1817
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /codon_start=1
                     /product="nuclear RNA export factor 3"
                     /protein_id="NP_001019312.1"
                     /db_xref="CCDS:CCDS41132.1"
                     /db_xref="GeneID:245610"
                     /db_xref="MGI:MGI:2685230"
                     /translation="MGRSSETNPLRRRMRCRRIFQQRFLNSPAHVSDTVHTSFYQQPA
                     MSNPPMHTRRYTPYGIPSRYQRVSVQKWNQTDVNMEGGSKPPERKMQRDKQDDTSENW
                     FKVTIPFGIKYDKKWLLNLIQSQCSIPFTPVQFHYEKMQAHFFVDNPNIAFMLKAISD
                     KILDETDNKPQSHRTPSVILQLTTNQQCATSQRVLNRQRLPFDQDLMTRPTDLALVPR
                     RYMTPSLSIHKEDMTQVNSEGEVAKVHAPDLEKICADQSSLSTTMPDKSSNINSILEL
                     FPKLLSLDGQESHKPTLCGPEDHKTLSACKEIFFGSESIKTMVLQFLKQYYFIYDNGD
                     RQGLLNAYHPEACFTLTIPFSSIDLSMNSLCEYFKFSRNMKILKDPYMRRQLLKHKKC
                     DIIHFLRTLPKTQHDLTSFVVDICLQTEKMLCFSVSGLFKEVDNSAQGCMHAFTRIFV
                     VTHDNSSELCIINDKLSVTNVHEVPSASTPVATSSTSYLPSFSQDQQEMVPTFCAQSG
                     VNVDRSQKSLHDDQWNYNRAIQSLALLKVEDTISEDKFTQTDPRS"
     exon            160..319
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            320..473
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            474..557
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            558..662
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            663..768
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            769..857
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            858..967
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1004
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1073
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1129
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1237
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1296
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1412
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1455
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1528
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1702
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1763
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..2978
                     /gene="Nxf3"
                     /gene_synonym="Gm384"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggatgaaac ttcctgtaag ggattccatc ttgtaacgga tgtttgaagc ctgctgtctg
       61 tcgtctttct cggcagctct cttcagtttt tcagctctag accacacaga agaacacaat
      121 aaggacattc gtgacgggaa acttgaggac ctaccatggg gcgcagttct gaaactaacc
      181 ccttgcgaag aagaatgaga tgcaggcgta ttttccaaca gagatttctt aactcgcctg
      241 ctcacgtcag tgatacagtg catacttcat tttatcagca gccagccatg agtaatcctc
      301 ccatgcatac ccgaagatac actccatatg gcattccatc ccgttatcag agagtcagtg
      361 tacagaaatg gaaccaaacg gatgttaaca tggagggagg gtcaaaacct ccagagagaa
      421 aaatgcagag ggacaaacaa gatgatactt cagagaactg gttcaaggtc acaattccct
      481 ttggcataaa atatgataag aagtggctgc tgaatttgat ccagagccag tgcagcatcc
      541 ctttcactcc ggtgcagttt cactatgaaa agatgcaggc ccattttttt gttgacaatc
      601 ccaacattgc ctttatgctg aaggccatca gtgacaagat tctagatgag actgataata
      661 agcctcagag tcacagaact ccatctgtga ttctgcagct gactacaaac caacaatgtg
      721 ctacttctca gcgagttctt aaccggcaga gacttccctt tgaccaagat ttgatgaccc
      781 gtcctactga cttggcactg gttcctagaa ggtatatgac tccttccttg agtatccata
      841 aagaggatat gacccaggtg aactctgaag gggaggtggc caaggtgcac gccccggatc
      901 tagaaaagat atgtgcagac caaagctctc tgagtactac catgccggat aagtccagta
      961 atataaattc aattctggaa ttgttcccca agttactaag cctggatgga caagaatcac
     1021 ataaaccaac tctctgtggt cctgaagatc acaagacctt atcagcttgc aaggaaattt
     1081 tttttggatc agaatccata aagacaatgg tcctacagtt cctgaagcag tattacttca
     1141 tctatgacaa tggagatcgg cagggactcc tcaatgctta tcatcctgag gcttgcttca
     1201 cactgaccat ccccttcagt tccattgact tatccatgaa cagcttgtgt gagtacttca
     1261 agtttagcag aaatatgaaa attctcaagg atccttatat gcggaggcag ctgctgaagc
     1321 acaagaaatg tgacattatt cacttccttc gtacattgcc caaaactcaa catgacctca
     1381 cctcctttgt ggtggacata tgtttgcaga cagaaaagat gctctgcttc tctgttagtg
     1441 ggttgttcaa ggaagtggac aacagcgctc aagggtgcat gcatgccttc actcggattt
     1501 ttgttgttac ccatgacaac agttcagaac tctgtatcat caatgacaag ctgtctgtga
     1561 ctaatgtcca cgaggttccc agtgcctcca cccctgtggc cacatcgtct accagttatt
     1621 tgccttcatt ctctcaagat caacaggaga tggtgccaac attctgtgcc cagtctgggg
     1681 tgaatgttga caggtctcaa aaatcccttc atgatgacca gtggaattac aacagagcta
     1741 tacaaagcct tgctttgctc aaggtagagg acacgatctc agaggataag ttcacacaga
     1801 cagatccaag atcctaagaa tagcacacca agaagaaatt cctaggtgtc actatcttat
     1861 ttcttcaaac ctctgctgag attttgttct agtacaaaca tgtaaacaaa ctgggatgtc
     1921 tagtttcatc ctggaagctg aagcctatct ggtagagccg actcaaattg ttctgtgtat
     1981 ttgtcacata tttaaggatc cacgcttctt atattttctt ttattataag ttttattaat
     2041 tttgttgagc attccccatt tttataatat attctggtca ctctcacccc tcaccatgtc
     2101 acatctcctt cctacccctg tccaacctcc ctcttcccta taagtccttg tctcatactt
     2161 acttgttttg ttttgcattg tgacccactg aggataaaca gggccaccta tgtgaccatg
     2221 tgtttggaac tatcaattga gatacctgtg ggtacataac taaagatagt gactatcttt
     2281 cccctagaat ccttcagtag ccaatagttt agcagagagg gataggaccc tcactctgtg
     2341 gttgactaat gaaagactta gtcttgtgca ggcccagtgg aggcagtctc acttgctgta
     2401 agattgcaat aattgtatca tgctctggag atactattga tgttgctggt tatgttaaat
     2461 accttcaaca tccactggtg caagcccgta ttatgagaat gaggatctcc aaggtaggac
     2521 tgctgtacat accgaagtcc tagactcaac catagggtac agtcctgcta ctgtaggcta
     2581 tatagtttca tacgttgaac atcctttcta accctgttaa aactgagtcc tatgtgccta
     2641 aagtattaat ccagtatttc gtgcagataa tattctttca ttagctgtaa acatttattc
     2701 acaattaaaa gcagcataat ttgtaggaaa tattattaca ggacacataa aagcctgtga
     2761 caaaagacag tccccatata tatgattgtc ttactataac aatccttggt atgaacaaat
     2821 aagagtaagg aaactgttat tgactttgta cttatattga aagcagtaac atccaggaaa
     2881 cttaggaaaa tatgttcaac taaaagtaca aacgttgccg caaacactga gataatttag
     2941 aaaaggaaaa taaagattat tactttaaga aaaaggaa
//
