LOCUS       NM_026532               2095 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus nuclear transport factor 2 (Nutf2), transcript variant
            1, mRNA.
ACCESSION   NM_026532
VERSION     NM_026532.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2095)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2095)
  AUTHORS   Sakakida,Y., Miyamoto,Y., Nagoshi,E., Akashi,M., Nakamura,T.J.,
            Mamine,T., Kasahara,M., Minami,Y., Yoneda,Y. and Takumi,T.
  TITLE     Importin alpha/beta mediates nuclear transport of a mammalian
            circadian clock component, mCRY2, together with mPER2, through a
            bipartite nuclear localization signal
  JOURNAL   J Biol Chem 280 (14), 13272-13278 (2005)
   PUBMED   15689618
REFERENCE   3  (bases 1 to 2095)
  AUTHORS   Keegan,C.E., Hutz,J.E., Else,T., Adamska,M., Shah,S.P., Kent,A.E.,
            Howes,J.M., Beamer,W.G. and Hammer,G.D.
  TITLE     Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd)
            mice is caused by a splicing mutation in a novel telomeric
            regulator
  JOURNAL   Hum Mol Genet 14 (1), 113-123 (2005)
   PUBMED   15537664
REFERENCE   4  (bases 1 to 2095)
  AUTHORS   Yamada,M., Mattaj,I.W. and Yoneda,Y.
  TITLE     An ATP-dependent activity that releases RanGDP from NTF2
  JOURNAL   J Biol Chem 279 (35), 36228-36234 (2004)
   PUBMED   15155737
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ059612.1, AK002461.1 and BC086773.1.
            
            On Oct 24, 2017 this sequence version replaced NM_026532.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003955.1, AK028410.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               CJ059612.1         124-243
            121-998             AK002461.1         2-879
            999-2095            BC086773.1         865-1961
FEATURES             Location/Qualifiers
     source          1..2095
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.05 cM"
     gene            1..2095
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /note="nuclear transport factor 2"
                     /db_xref="GeneID:68051"
                     /db_xref="MGI:MGI:1915301"
     exon            1..173
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /inference="alignment:Splign:2.1.0"
     exon            174..298
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..583
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /codon_start=1
                     /product="nuclear transport factor 2"
                     /protein_id="NP_080808.1"
                     /db_xref="CCDS:CCDS22617.1"
                     /db_xref="GeneID:68051"
                     /db_xref="MGI:MGI:1915301"
                     /translation="MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQ
                     QFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQM
                     FLLKNINDAWVCTNDMFRLALHNFG"
     exon            299..370
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /inference="alignment:Splign:2.1.0"
     exon            371..469
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /inference="alignment:Splign:2.1.0"
     exon            470..2067
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2048..2053
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /note="hexamer: AATAAA"
     polyA_site      2067
                     /gene="Nutf2"
                     /gene_synonym="2700067I02Rik; Ntf2; Ntf3; PP15"
                     /note="major polyA site"
ORIGIN      
        1 attctgggaa atgtagttct agctaagctc actaaggcgt ataaggagca tactgggact
       61 acgtttccct gagtgcagcg ggacgggcga gggaaggcaa gggggaaggg acagtcggtc
      121 gcagaccgcg ctgggttgcc gccgccgctg ccgccatcgt gccagcccca cgggtctcag
      181 aggtgggtga ccctccagga tgggagacaa gccaatttgg gagcagattg gatccagctt
      241 tattcaacat tactaccagt tatttgataa cgacagaacc caactaggcg caatttatat
      301 tgatgcatca tgccttacat gggaaggaca gcagttccag gggaaagctg ccattgtgga
      361 gaagctatct agccttccgt tccagaaaat tcagcatagc atcacggcgc aggaccacca
      421 gcctacacca gatagctgca tcatcagcat ggttgtgggc cagctcaagg ctgatgaaga
      481 tcccatcatg ggtttccacc agatgtttct attaaagaac atcaacgatg cttgggtttg
      541 caccaatgac atgttcaggc ttgccctgca caacttcggc tgacctcctc ctggccacag
      601 tcacgctgtt tcctcctccc tcttcccaat cctagctcac tcctccagat gctccaaata
      661 tcatacacaa acgagcaggg ccgaggcggg agcgggtgca gggcgcttct gtcaccacgg
      721 tgttgtgcat gatgtttgga tgctagacta gtcgcatctg acaggaagtt tgtgttgtac
      781 cagcgcatgc cttggaaaga cttaagtaat gcaaacgatt gtcgggtttt gtttttgttt
      841 tattttttgt tttgttttgt ttttttaatc tactgacaag ttgctctagt aacccaaaga
      901 agtgaaggag aaagcagctg cctcaccaac cgcccagata ttgatttgtt cagatgtttc
      961 aatgcctcat gatacaataa aaccacaaaa attttcttaa cagtttaaat tgttttaatt
     1021 agttaagtag ttggctgggc atcaacagtt ccagcccatt gtctcacttt ccccaccccc
     1081 atctgcctca cctcaacaga acctactgca aggagcagat tcactcaagt ggctaagctc
     1141 gcatgtctgc gggccggggc agagttctct ccagccccag ggttttggaa cgcaggcctg
     1201 gcctgaagct tctcttggac tgaaggctct tcagtcagct ctgtctgata ccacctgtgg
     1261 cctctgctct gtagatttgg gtctagtagc agggtagata ttctgtagca gctagaaagg
     1321 ccttagcaaa tatggcttcc catatttata ccctctgggt tgaagtccta aatgtagggg
     1381 cctgctctat acccaaaata agtgacatgc agatgcccac attccccaag caaagcgaga
     1441 gatgctgtgc tgcctgcttg ggatatcaga gccaggcgcc attaggtgga gtataaattc
     1501 cacactggaa ggaagcagtg tgaaggagtg ctctaactct cccctcaaga cctgtgcagg
     1561 gcatttacac accatcttcc tactttccac ataccccata cactcttcaa atcccaggaa
     1621 atcttaacta gtatggcagt ttctgccctg tttcttagtc tgggcacagg tcttgctcag
     1681 taccgatata gcttttcatc cttgagacct ctggatagta taaagctact aaaatagcaa
     1741 ctgcaagcta gaaccaagcc caggatttgg ggtttaggat tggctaggca cacctgaaca
     1801 tgcccttctc cctgctctcc tgcattgtga ggggagagta aagatttcca catactccac
     1861 aggttgcctg gttagaccag catagtcctg gacgctacac agaaggttcc agtgggattg
     1921 atctctagct gctgtgtatt gggggaagta ggggtgggag agaggtagat gccagctgcc
     1981 tcttaatcca ccctgtataa aatctgcaat acagcttctt ccatgtacct gtgcctgaaa
     2041 tgtctgcaat aaagaggtgt ttgtaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
