LOCUS       NM_001359995            2494 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus nucleoporin 54 (Nup54), transcript variant 1, mRNA.
ACCESSION   NM_001359995 XM_006534956
VERSION     NM_001359995.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2494)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   2  (bases 1 to 2494)
  AUTHORS   Suntharalingam,M. and Wente,S.R.
  TITLE     Peering through the pore: nuclear pore complex structure, assembly,
            and function
  JOURNAL   Dev Cell 4 (6), 775-789 (2003)
   PUBMED   12791264
  REMARK    Review article
REFERENCE   3  (bases 1 to 2494)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122365.4.
            
            On Jan 24, 2018 this sequence version replaced XM_006534956.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.70150.1,
                                           SRR1660811.143633.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               AC122365.4         183075-183270       c
            197-358             AC122365.4         182293-182454       c
            359-442             AC122365.4         179110-179193       c
            443-595             AC122365.4         178872-179024       c
            596-822             AC122365.4         176171-176397       c
            823-1010            AC122365.4         173694-173881       c
            1011-1207           AC122365.4         172345-172541       c
            1208-1262           AC122365.4         171048-171102       c
            1263-1356           AC122365.4         170553-170646       c
            1357-1464           AC122365.4         167588-167695       c
            1465-1584           AC122365.4         165852-165971       c
            1585-1695           AC122365.4         165524-165634       c
            1696-2494           AC122365.4         163611-164409       c
FEATURES             Location/Qualifiers
     source          1..2494
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 46.75 cM"
     gene            1..2494
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /note="nucleoporin 54"
                     /db_xref="GeneID:269113"
                     /db_xref="MGI:MGI:1920460"
     exon            1..196
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..1824
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nucleoporin 54kDa; nuclear pore complex protein Nup54;
                     nucleoporin Nup54; 54 kDa nucleoporin"
                     /codon_start=1
                     /product="nuclear pore complex protein Nup54 isoform 1"
                     /protein_id="NP_001346924.1"
                     /db_xref="GeneID:269113"
                     /db_xref="MGI:MGI:1920460"
                     /translation="MAFNFGAPSGTSGTSTATAAPAGFGGLETANSTAGGFNFGGFGL
                     TANPAVNFNIGNFGVSTTSATPFNFGNSLASAGGFGGFGTTTTTAGSAFSFSAPTNTG
                     STGLLGGTQNKGFGFGTGFGTTTGTGTGLGTGLGTGLGFGGFNTQQQQQQQQTSLGGL
                     FSQPTQAPAQSTQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPP
                     VEFTQENPFCRFKAVGYSCMPNNKDEDGLVVLIFNKKETDIRSQQQQLVESLHKVLGG
                     NQTLTVNVEGIKTLPDDQTEVVIYVVERSPNGTSRRVPATTLYAHFEQANIKAQLQQL
                     GVTLSMTRTELSPAQIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLR
                     RLKVQDQMTKQHQTRLDIISEDISELQKNQTTTMAKIAQYKRKLMELSHRTLQVLIKQ
                     EIQRKSGYAIQADEEQLRVQLDTIQGELNAPTQFKGRLNELMSQIRMQNHFGAVKSEE
                     KYYIDADLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNETIHSRGGVFS"
     exon            197..358
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            359..442
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            443..595
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            596..822
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            823..1010
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1207
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..1262
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1356
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1464
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1584
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1695
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..2494
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2465..2470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /note="hexamer: AATAAA"
     polyA_site      2489
                     /gene="Nup54"
                     /gene_synonym="3110079L04Rik; 54kDa"
                     /note="major polyA site"
ORIGIN      
        1 gcttagaccg ggaaggaggc ggaactaatg gtacggaccg cctgacggtt cccagccgga
       61 cagaagagcg gagggcactg ggcgtcgcgc cgcgcgagcc cggggccatc taagtgctgc
      121 tcccgcgaca tggctttcaa ttttggggct ccttcgggca cttcgggcac ctctacagcc
      181 accgcggcac cggcgggatt tggtgggctt gagactgcca actccaccgc cggtgggttt
      241 aattttgggg gtttcggatt aaccgctaac cctgcagtga actttaatat tgggaatttc
      301 ggtgtttcta ctacctcggc gactccgttc aattttggta acagtctggc gagtgcaggt
      361 gggtttggag gatttggaac aacaactaca actgcaggct ctgccttcag cttttcagcc
      421 ccaacaaaca caggcagtac aggccttctc ggtggcactc agaacaaagg ttttggcttt
      481 ggtactggtt ttggcacaac gacgggaact ggcactggtt taggcactgg cttgggaacc
      541 ggacttggat ttggaggatt taatacccag cagcagcagc agcagcagca gacttcttta
      601 ggtggtctct tcagtcagcc gacccaggct cctgcacagt ctacccagct catcaacact
      661 gccagcgcac tttctgctcc aacgctactg ggggatgaga gagacgccat cttggcaaag
      721 tggaaccagt tgcaggcctt ctggggaaca ggaaaaggat atttcaataa taacattcct
      781 ccagtggagt ttacccagga gaatcccttt tgccggttta aggctgtagg ctatagttgt
      841 atgcccaata ataaagatga agatggacta gtagttttaa ttttcaacaa aaaagaaaca
      901 gatattagaa gccagcaaca gcaattggta gaatcattgc ataaagtttt gggaggaaac
      961 cagaccctta cggtcaatgt ggagggcatt aagacgttgc cggatgatca gacggaagtt
     1021 gtcatttatg ttgttgagcg ttctccaaat ggcacctcga gaagagttcc agcgacaaca
     1081 ctgtatgccc actttgagca agccaacatt aaagcccagc tgcagcagct tggggtgacc
     1141 ctttctatga ccaggacaga gctgtctccc gctcagatca agcagctctt acaaaaccct
     1201 cccgcaggtg ttgatcctat tatttgggaa caggccaagg tggataaccc agactctgaa
     1261 aagttaattc ctgtaccaat ggtgggtttc aaagaattgc ttcgaagact gaaggttcaa
     1321 gatcagatga ctaagcagca tcagaccaga ctagatatca tatctgaaga tattagtgaa
     1381 ctgcaaaaaa atcaaactac gactatggcc aaaatagcac aatacaagag gaaactgatg
     1441 gagctctccc acaggacctt acaggtccta atcaaacagg aaatccagag gaagagtggc
     1501 tatgcgatcc aggctgatga agagcagttg cgggttcagc tagatactat tcaaggggaa
     1561 ctgaatgcgc ccactcagtt caaaggtcgg ctgaatgagc tgatgtccca gatcaggatg
     1621 cagaatcatt ttggagccgt gaaatctgaa gaaaagtact acatagatgc agacctgtta
     1681 cgagaaatca agcagcattt gaaacaacaa caggaaggcc ttagccactt gattagcatc
     1741 ataaaagatg acctagaaga cataaaactg gtagaacatg gattgaatga gaccatccat
     1801 agcagaggcg gtgtctttag ctgaccgttt acagacttgt tgcagagatt gataaaatgc
     1861 gtctccttgc tacatcgagc cttcttcacg atgaccacat ggccggggaa aaggatgctt
     1921 ctcctcactg ggatgtctgc gatcctcaga ggttactgta cgttaaatct gaaatggtca
     1981 ccacaaagcc cttcaaagag aatctttgaa aagtttatat ctaaaagctg tatttacttt
     2041 taaagaagtg ttacccaaag catacactgt tgttcatttt ataacagcgt taagcgtagt
     2101 cacggagcct gatggttatt ctccgttctc ctctccatag cacagagcgc cacagagcta
     2161 cttcctacat gacacaacaa actgggattc catgcctgtt ggaggctgtg cttcagggta
     2221 taaatgcatt tcagctttta tatctgtgaa atcagctgtg gagagtaaag aaaatcccaa
     2281 agtatttaat gatttgtgtg gttttccttt tgttctagaa agacttgaaa atatattttt
     2341 atattatttt acttatttag aacttacaga aaatacctaa ccggttagga tatgacaaaa
     2401 tcaccacttt tgcaagctgt tttgttttgt tttgtttttt tatttctaaa aatgaaatcc
     2461 ttaaaataaa ttgttaattt gtaattttat gtaa
//
