LOCUS       NM_027191               1282 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleoporin 37 (Nup37), transcript variant 2, mRNA.
ACCESSION   NM_027191
VERSION     NM_027191.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1282)
  AUTHORS   Peng,Y., Shen,J., Gao,Y., Dai,W., Liang,S., Chen,J., Gao,L.,
            Lin,Y., Cai,L., Qin,L., Cui,Y., Liu,J. and Diao,F.
  TITLE     Nucleoporin37 may play a role in early embryo development in human
            and mice
  JOURNAL   Mol Hum Reprod 28 (6) (2022)
   PUBMED   35583302
  REMARK    GeneRIF: Nucleoporin37 may play a role in early embryo development
            in human and mice.
REFERENCE   3  (bases 1 to 1282)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1282)
  AUTHORS   Lupu,F., Alves,A., Anderson,K., Doye,V. and Lacy,E.
  TITLE     Nuclear pore composition regulates neural stem/progenitor cell
            differentiation in the mouse embryo
  JOURNAL   Dev Cell 14 (6), 831-842 (2008)
   PUBMED   18539113
REFERENCE   5  (bases 1 to 1282)
  AUTHORS   Suntharalingam,M. and Wente,S.R.
  TITLE     Peering through the pore: nuclear pore complex structure, assembly,
            and function
  JOURNAL   Dev Cell 4 (6), 775-789 (2003)
   PUBMED   12791264
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK040463.1 and BE951864.1.
            
            On Oct 29, 2008 this sequence version replaced NM_027191.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011102.1, AK040463.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1262              AK040463.1         2-1263
            1263-1282           BE951864.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 43.7 cM"
     gene            1..1282
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /note="nucleoporin 37"
                     /db_xref="GeneID:69736"
                     /db_xref="MGI:MGI:1919964"
     exon            1..81
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            82..299
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..1124
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /note="nup107-160 subcomplex subunit Nup37"
                     /codon_start=1
                     /product="nucleoporin Nup37"
                     /protein_id="NP_081467.2"
                     /db_xref="CCDS:CCDS24107.1"
                     /db_xref="GeneID:69736"
                     /db_xref="MGI:MGI:1919964"
                     /translation="MKQDATRNAAYTVDCEDYVHVVEFNPFESGDSGNLIAYGGSNYV
                     VVGMCTFQEEETDIEGIQYKTLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADL
                     KIRLFTSDLQDKNEYKVLEGHSDFINDLVFHPKEGQELASVSDDHTCRIWNLEGKQTA
                     HFLLHSPGMSVCWHPEETFKLMVAEKNGTIRFYDLMAQQAILSLQSEQTPLMSAHWCL
                     KNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHLFRWSAISENLFATTGYPGKM
                     ASQFQIHHLGHSQPVLIGSVAVGSGLSWHRTLPLCAVGGDHKLLFWVTEI"
     exon            300..424
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            425..497
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            498..592
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            593..683
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            684..865
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            866..916
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1010
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1272
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1251..1256
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /note="hexamer: GATAAA"
     polyA_site      1272
                     /gene="Nup37"
                     /gene_synonym="2410003L22Rik; 2810039M17Rik"
                     /note="major polyA site"
ORIGIN      
        1 ccgacccgga agcagagcgg gcgcacgccc tggccaccta tggtcgggag agccttgccc
       61 aggtcgcctc ccctgcttta gtttcctgac aggcaataaa caactatttg attcttacaa
      121 ctgctccagc tttgggatac aagatgaagc aagatgctac aagaaatgct gcgtacaccg
      181 tggattgcga agattatgtg cacgtggtag aatttaatcc ctttgagagt ggagattcag
      241 gaaacctgat tgcatatggc ggcagtaatt atgtggttgt tggcatgtgt acgtttcagg
      301 aggaagaaac agacatcgaa gggattcagt ataaaacact acgaacattt caccatggag
      361 tccgagttga cggcattgcc tggagcccag agaccaaact tgactcgctg cctcctgtaa
      421 tcaaattttg tacttcagct gctgatttga agattagatt atttacttca gatcttcaag
      481 ataaaaatga atataaggtt ttggagggcc actcagactt cattaatgat ctggtgttcc
      541 atcccaaaga aggccaggag ctcgcaagcg tgagtgacga ccacacctgc aggatttgga
      601 acttggaagg aaagcagaca gctcattttc ttctgcattc tcctggaatg agtgtatgct
      661 ggcatcccga ggaaactttc aagctaatgg ttgcagagaa gaatggaaca atccggtttt
      721 atgatctaat ggctcagcag gcaattttat ctcttcagtc agagcagaca cccttaatgt
      781 cagcacactg gtgcttaaaa aacaccttca aagttggtgc tgtggcagga aatgattgga
      841 ttatttggga tatcactcgg tccagttatc ctcaagaaac aagacctgtt cacatggacc
      901 gagcacactt atttaggtgg tcggccatta gtgaaaactt gtttgcaacc actggatatc
      961 ctggcaaaat ggccagtcag tttcagattc atcatttagg gcactctcag cccgtcctca
     1021 ttggttctgt agctgtcggt tctggtcttt cctggcatag aacacttcca ctgtgtgcag
     1081 ttggaggcga ccacaagctc ttgttctggg tgacagaaat atgattttcc tctgtatttt
     1141 tgatccttca ctttgtattt ttagtatata ttttggaaaa atccttattt ttatatcaaa
     1201 catactgtaa atctagaaat gcctcagttg tcttttctga taaataaaat gataaagact
     1261 acatgaaaaa taaaaaaaaa aa
//
