LOCUS       NM_133227               6420 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleoporin 155 (Nup155), mRNA.
ACCESSION   NM_133227
VERSION     NM_133227.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6420)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6420)
  AUTHORS   Preston,C.C., Storm,E.C., Burdine,R.D., Bradley,T.A., Uttecht,A.D.
            and Faustino,R.S.
  TITLE     Nucleoporin insufficiency disrupts a pluripotent regulatory circuit
            in a pro-arrhythmogenic stem cell line
  JOURNAL   Sci Rep 9 (1), 12691 (2019)
   PUBMED   31481660
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6420)
  AUTHORS   Preston,C.C., Wyles,S.P., Reyes,S., Storm,E.C., Eckloff,B.W. and
            Faustino,R.S.
  TITLE     NUP155 insufficiency recalibrates a pluripotent transcriptome with
            network remodeling of a cardiogenic signaling module
  JOURNAL   BMC Syst Biol 12 (1), 62 (2018)
   PUBMED   29848314
  REMARK    GeneRIF: NUP155 regulates cardioplasticity of a sub-network
            embedded within a larger framework of genome integrity, and
            exemplifies how transcriptome cardiogenicity in an embryonic stem
            cell genome is recalibrated by nucleoporin dysfunction
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6420)
  AUTHORS   Hutchins,J.R., Toyoda,Y., Hegemann,B., Poser,I., Heriche,J.K.,
            Sykora,M.M., Augsburg,M., Hudecz,O., Buschhorn,B.A., Bulkescher,J.,
            Conrad,C., Comartin,D., Schleiffer,A., Sarov,M., Pozniakovsky,A.,
            Slabicki,M.M., Schloissnig,S., Steinmacher,I., Leuschner,M.,
            Ssykor,A., Lawo,S., Pelletier,L., Stark,H., Nasmyth,K.,
            Ellenberg,J., Durbin,R., Buchholz,F., Mechtler,K., Hyman,A.A. and
            Peters,J.M.
  TITLE     Systematic analysis of human protein complexes identifies
            chromosome segregation proteins
  JOURNAL   Science 328 (5978), 593-599 (2010)
   PUBMED   20360068
REFERENCE   5  (bases 1 to 6420)
  AUTHORS   Zhang,X., Chen,S., Yoo,S., Chakrabarti,S., Zhang,T., Ke,T.,
            Oberti,C., Yong,S.L., Fang,F., Li,L., de la Fuente,R., Wang,L.,
            Chen,Q. and Wang,Q.K.
  TITLE     Mutation in nuclear pore component NUP155 leads to atrial
            fibrillation and early sudden cardiac death
  JOURNAL   Cell 135 (6), 1017-1027 (2008)
   PUBMED   19070573
  REMARK    GeneRIF: These human and mouse studies indicate that loss of NUP155
            function causes atrial fibrillation by altering mRNA and protein
            transport and link the nuclear pore complex to cardiovascular
            disease.
REFERENCE   6  (bases 1 to 6420)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 6420)
  AUTHORS   Suntharalingam,M. and Wente,S.R.
  TITLE     Peering through the pore: nuclear pore complex structure, assembly,
            and function
  JOURNAL   Dev Cell 4 (6), 775-789 (2003)
   PUBMED   12791264
  REMARK    Review article
REFERENCE   8  (bases 1 to 6420)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 6420)
  AUTHORS   Zhang,X., Yang,H., Yu,J., Chen,C., Zhang,G., Bao,J., Du,Y.,
            Kibukawa,M., Li,Z., Wang,J., Hu,S., Dong,W., Wang,J., Gregersen,N.,
            Niebuhr,E. and Bolund,L.
  TITLE     Genomic organization, transcript variants and comparative analysis
            of the human nucleoporin 155 (NUP155) gene
  JOURNAL   Gene 288 (1-2), 9-18 (2002)
   PUBMED   12034489
REFERENCE   10 (bases 1 to 6420)
  AUTHORS   Radu,A., Blobel,G. and Wozniak,R.W.
  TITLE     Nup155 is a novel nuclear pore complex protein that contains
            neither repetitive sequence motifs nor reacts with WGA
  JOURNAL   J Cell Biol 121 (1), 1-9 (1993)
   PUBMED   8458861
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO433695.1, AK086426.1, AK129217.1 and CO040753.1.
            
            On Jan 18, 2008 this sequence version replaced NM_133227.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK129217.1, AK036575.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                CO433695.1         1-27
            28-2564             AK086426.1         2-2538
            2565-6173           AK129217.1         2528-6136
            6174-6420           CO040753.1         1-247               c
FEATURES             Location/Qualifiers
     source          1..6420
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 3.82 cM"
     gene            1..6420
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="nucleoporin 155"
                     /db_xref="GeneID:170762"
                     /db_xref="MGI:MGI:2181182"
     exon            1..290
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..4309
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="nucleoporin Nup155; 155 kDa nucleoporin"
                     /codon_start=1
                     /product="nuclear pore complex protein Nup155"
                     /protein_id="NP_573490.3"
                     /db_xref="CCDS:CCDS37034.1"
                     /db_xref="GeneID:170762"
                     /db_xref="MGI:MGI:2181182"
                     /translation="MPSVLGSMMVASTSAAASLQEALENAGRLIDRQLQEDRMYPDLS
                     ELLMVSAPNSPTVSGMSDMDYPLQGPGLLSVPSLPEISTIRRVPLPPELVEQFGHMQC
                     NCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPH
                     VRHLLVLATPVDIVILGLSYANVQTGSGILNDSMCGGMQLLPDPLYSLPTDNTYLLTI
                     TSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSED
                     DPIVQIEIDNSRNILYTRSEKGVIQVYDLGHDGQGMSRVASVSQNAIVSAAGNIARTI
                     DRSVFKPIVQIAVIESSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRL
                     PPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQM
                     TTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGS
                     LMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVS
                     AWATRAFFRYGGEAQMRFPATLPTPSNVGPILGSPMYSSSPVPSGSPYPNPSSLGTPS
                     HGAQPPTMSTPMCAVGSPAMQAASMSGLTGPEIVYSGKHNGICIYFSRIMGNIWDASL
                     VVERVFKSSNREITAIESSVPVQLLESVLQELKGLQEFLDRNSQFSGGPLGNPNTTAR
                     VQQRLVGFMRPENGNTQQMQQELQRKFQEAQLSEKISLQAIQQLVRKSYQALALWKLL
                     CEHQFSVIVGELQKEFQEQLKITTFKDLVIRDKEVTGALIASLINCYIRDNAAVDGIS
                     LHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKTERERMLRESLKEYQKISNQVDLP
                     SVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSY
                     KCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRS
                     KDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMARVDQNRVRYMDLLWRYYEKN
                     RSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEE
                     KMEVARIQLQIQETLQRQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLA
                     VIHCAGYSDPILVHTLWQDIIEKELNDSVALSSSDRMHALSLKLVLLGKIYAGTPRFF
                     PLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSP
                     LHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITG
                     NFKSLQAKLERLH"
     exon            291..428
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            429..525
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            526..596
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            597..689
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            690..856
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            857..962
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1036
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1128
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1226
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1379
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1480
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1651
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1762
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1857
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1946
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2009
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2157
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2224
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2340
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2438
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2439..2569
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2570..2761
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..2900
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3036
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..3190
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3191..3295
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3296..3450
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3451..3580
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3581..3694
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3695..3815
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3816..3926
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            3927..4063
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            4064..4170
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     exon            4171..6404
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4350..4355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="hexamer: AATAAA"
     polyA_site      4375
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="major polyA site"
     regulatory      6378..6383
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="hexamer: AATGAA"
     polyA_site      6404
                     /gene="Nup155"
                     /gene_synonym="D930027M19Rik; mKIAA0791"
                     /note="major polyA site"
ORIGIN      
        1 gcgtcatgac ctggcgccca gttattcgtt ttccgcgcgc gttccgagga gcggttttgg
       61 gctctcttcg tttttctcac ggttctccac gggtttggag tgtttctata aggcggtggc
      121 cacgattgcc gacatgccat cggtgctggg ctctatgatg gtggcctcta cgtcggccgc
      181 cgcctccctg caggaagctt tggaaaacgc ggggaggctt atcgatcgac agttgcaaga
      241 agaccgcatg tacccggacc tttctgagct gctcatggtg tcggccccaa acagtcctac
      301 tgtttctgga atgtccgaca tggattaccc tctgcaagga ccaggtttgc tgtcagtacc
      361 cagccttcca gagatcagca ctatccggag agttcccctc ccgcctgagc tggttgaaca
      421 gtttggacac atgcagtgca actgcatgat gggcgttttc cccccgatca gcagagcctg
      481 gcttacgatt gacagtgaca tattcatgtg gaactatgaa gatggaggtg accttgccta
      541 ttttgatgga ctcagtgaga caattcttgc tgtggggctt gtgaaaccaa aagctggcat
      601 ctttcaacct catgtaagac acttgctggt tttggcaacc cctgtggata tagtaattct
      661 tggactcagc tatgctaatg tacaaacagg ttctggcatt ctcaatgaca gcatgtgtgg
      721 cggcatgcag ctgcttccag atcccttata ttctcttccc acggacaaca cgtacctttt
      781 aacaatcacg tccacggata atggcagaat ctttctggct ggaaaggatg gctgtttgta
      841 cgaagtagca taccaagcag aagcaggctg gttcagtcaa agatgtagga agatcaatca
      901 ctccaagagc tcgctctcct tcctggtgcc ttccttgctg cagttcacgt tctcagaaga
      961 tgatcctatt gttcaaattg aaattgataa ttccagaaat attttgtata cacgatcgga
     1021 gaaaggagtt atacaggttt atgatttggg ccatgatgga caggggatga gtagagttgc
     1081 ttcagtttca cagaatgcca ttgtctctgc tgctggaaac attgctagga ctattgatcg
     1141 ttccgtcttt aagccaattg ttcagatagc tgtgattgag agttctgaat ccctggactg
     1201 tcagttactg gctgtcactc acgcaggtgt aaggctgtat ttcagcactt gtccgtttag
     1261 acagccatta gctcggccga atacactgac actggtccac gtccggttac ctcctggatt
     1321 ttcagcatca tcaacagtgg aaaagccttc aaaagtgcac aaagcacttt acagtaaagg
     1381 aattttactg atgacagcct cagaaaatga agataatgac attttatggt gtgtcaacca
     1441 tgatacattt ccttttcaaa agccaatgat ggaaactcag atgacaaccc gtgttgatgg
     1501 tcattcctgg gctctctctg caatagatga attaaaagta gataaaataa ttacaccgtt
     1561 aaataaagat catattccaa taactgattc gccagttgtt gtacaacagc acatgttgcc
     1621 tccaaagaaa ttcgttctcc tctcagcaca gggtagtctt atgtttcaca agcttagacc
     1681 tgtagatcag ctgagacatc tgcttgtgag taacgtggga ggggatggag aagagattga
     1741 gagattcttc aaattacatc aggaagacca agcttgtgca acttgcctta ttcttgcttg
     1801 ttccactgct gcctgtgaca gagaagtgtc tgcttgggca acacgggcat tctttaggta
     1861 tggtggtgag gcacagatga gatttccagc tactcttcct actccaagca acgttggtcc
     1921 catccttggc tctcctatgt attctagttc tcctgtccct agtgggagtc cctatccaaa
     1981 tccatcctcc ttggggacac catcccatgg tgctcagccg cctaccatgt caaccccaat
     2041 gtgtgctgtt ggaagcccag ccatgcaggc tgcaagcatg agtggtttga ctgggccaga
     2101 gattgtgtac tcaggaaaac acaacggtat ttgcatttac ttttctcgaa tcatgggaaa
     2161 tatttgggat gcgagcttag ttgttgaaag agtattcaag agttccaaca gggagatcac
     2221 tgcaattgag agcagtgtgc ccgtccagct gctggagtca gtgctgcagg agctgaaggg
     2281 cttgcaggag tttctagaca gaaactccca gttttcaggt ggacccctgg gaaatccaaa
     2341 tactactgcc agagtgcagc agcggctggt tgggttcatg cgtcccgaga atggaaacac
     2401 ccagcaaatg caacaggagc tgcagaggaa gtttcaggag gctcaactga gtgaaaagat
     2461 ttcacttcag gcgatccagc agctggttag aaaatcgtac caagctctgg ctctctggaa
     2521 actcctttgt gaacatcagt tttctgtcat tgtcggagaa cttcaaaagg aatttcaaga
     2581 gcagctgaag atcaccacct ttaaggatct ggtgatcagg gacaaagagg tcactggagc
     2641 attaattgct tctcttatca actgctacat cagagacaac gccgccgtag acggcattag
     2701 cttacatctg caggacacct gtccgcttct gtatagcaca gacgatgcag tttgttctaa
     2761 ggcaaatgag ctccttcagc gttcccgaca agttcagagt aagactgaga gagagaggat
     2821 gttacgggag tcactgaagg agtatcagaa gatcagcaac caagtggacc ttcccagtgt
     2881 ctgtgctcag tataggcaag tgcgttttta tgagggtgtg gtggaacttt ctcttactgc
     2941 tgccgagaaa aaagatcctc agggtcttgg actccatttc tataaacatg gggaaccaga
     3001 agaggatgtg gttggtcttc agactttcca agagagatta aacagttaca agtgcattac
     3061 ggatactctg caagagctgg taaatcaaag taaggcagct ccccagtctc ccagtgtacc
     3121 caaaaagcct gggcctccag tgctgtcatc tgatcccaac atgctgagca atgaagaagc
     3181 aggacatcac tttgaacaaa tgcttaaatt ggcacagcgg tccaaggatg agctcttcag
     3241 cattgctctt tataactggc taatacaagc tgaccttgca gataaactgc tacagattgc
     3301 gtcaccattt ctggagccac atcttgtgcg aatggccaga gtggatcaga acagagtccg
     3361 ctatatggat ttactctgga ggtattacga gaagaacagg agcttcagca gcgccgctcg
     3421 ggtcctatcc aagttggcgg acatgcacag cacagaaatt tcacttcagc agcgactaga
     3481 atacattgct cgagccatcc ttagtgcgaa aagttccact gccatctcat ccatagctgc
     3541 agatggtgaa ttcctgcatg agttagaaga gaaaatggaa gttgctagaa tccaacttca
     3601 gatacaagag acactacaaa ggcagtactc ccatcattct tcagtgcagg atgcaatttc
     3661 tcagctggat tctgagctca tggacattac taagctctat ggggaatttg ctgacccgtt
     3721 taaacttgca gagtgtaaac ttgcagtcat tcattgcgct ggttactcag atcccatatt
     3781 ggtgcacaca ctctggcaag atatcataga gaaagaattg aacgacagcg tagcattgag
     3841 ctcgtcagat cgaatgcatg ctctcagcct caagcttgtc ctcctcggca aaatctatgc
     3901 tgggacgcct cggtttttcc ctctggattt tatcgtgcag ttcttggagc agcaagtttg
     3961 taccttaaac tgggatgtgg ggtttgtgat acagaccatg aatgaaatcg gcgtgccttt
     4021 acctaggctg ctagaagttt atgatcagct cttcaaatca cgggatccat tctggaacag
     4081 agtgaaaagc ccactgcacc ttctggattg tatccatgta ctgttgacaa gatatgttga
     4141 gaatcctagc ctagttttaa attgtgagag gagaaggttt acaaatctct gcctggatgc
     4201 cgtctgtgga tatctggtgg aacttcagtc aatgagttct tcagtagcag tacaagccat
     4261 cactgggaat tttaaatcgc tccaagcaaa gctggaacgg ctccattgat tactgtagta
     4321 tattttcttg tttgcatttt ggtctgtaaa ataaaagctc agctgggtcc agaaatcagg
     4381 tgttgtatat ctaagaattt tggtagaaca tttttttaat gaatgatagt tatctacaaa
     4441 tagtacattt gccaaatgat ttagtttttt tttttatgat tagtattttt tttaattgat
     4501 aagttgggcc cagatatgta gctcagtggt aaaatgtttg tatagtgtgt aaaaagttag
     4561 tagtaccaca cacagacaca gcagtctatg aacagctgga ataagactgt gtatgattat
     4621 gacacacaaa gattttgaat ttcactagtg gtaacaattt tgactttgta ttatttatct
     4681 acaggtttat gtaggatgtt agtattaaaa cttataggct atgccaggtt tggtagcaca
     4741 tgcctttaag tccagcactt ggggaagcag tggcaggcgg ctctttagaa ctcactgaga
     4801 tttccaggcc aggggctaca cagtgagacc ttatcttcaa acaaacaaac aaacaaacaa
     4861 acaccttata ggctgggtct gttcccttag tgctagattc tgtaacagtc ttaattagtc
     4921 atttttaggt taatatttta tcaattacag ccctttatgt tctctcttcc tctttttttc
     4981 tctctccctc tcaccataag tacatacatt agattttatg tatacattta tatatgtgtg
     5041 tgcaggctat atatgtatgt tgtatgtata tacaggattg tttgagcatg tgattgtaac
     5101 acttctatgt acttaaaatc ttcatgatca cccagctgta atggtgctcc cctttaatgg
     5161 cggcactcgg gagtgtgggg gagagtcaga gtggccagtc tggtctacat actgagttac
     5221 aattcaacca cagctctaca gggactactg tttccttaga accctcactg tctaactgta
     5281 tgcttcaagc cagcaacagt agcagcaaat taaattacaa attaaattcc tggctctctg
     5341 gtcagatcta ccaagccaaa aactgtggca taaatgccag tctctgtgtc ttaacaaccg
     5401 ttccagtaga tgcagattta tgtcttattg acttgtaaat cctgttttat ctagtttgtt
     5461 tttgtttttt aatactgatg ggttttcatg ctaaacaggt aaatgtgctc ccactgaagt
     5521 ttaacatgtt aaaagaactt actaaactaa gtgttccaaa ttattatcaa agacaaaaaa
     5581 acctgagaat tactaaggct aaccaagaga agagagagag aaaaagtgaa aaacaactgg
     5641 tttctactcc ttagttgttt tgttatttta tttttgcagc agattgtgac atagcgtagg
     5701 ctagtgtcaa acctaactgc ctagagtgat gttgaaattc cgattatccg gcccctacca
     5761 cctgtgtgct aagactgtag gcaggcttca cagtgcctac tttttgtgat gcaggctgtt
     5821 aaattaagcg agcaccttac ctactgaatg agttaagttc acagtcctca actccccacc
     5881 cccactcctt tttctttttc tcttttcttt cctttccttt tctcttctct tctcttctct
     5941 tcttttcttt tttttttttt ttgctaggtc tcactaatat agcccaggct agctgcaaac
     6001 acatgttgat cctcctgcct cagacttcca agtactggaa atccaagcat gtgccaccat
     6061 acccagcctc cagtgttatt tatactgttg gaagtattct cttctgtttg ttggcactgg
     6121 tggaaattgg gcagtttgtg agtacacctg aatatatttc tacttttatc ttctcctgcg
     6181 attacggatt tctttttcac aataccgtag aatgcaattc cgttttcact ttgaatgtgt
     6241 atttcctaaa agatcaacgt aatgctcatt gggtgtcact acctcgtgtt tctcagtttt
     6301 tcatcttatt aagtaatttt atagcatttg atatattaat ggttttatgc atttatactt
     6361 ctgtcatgct cattttaaat gaaggtcttg tttaaatgct ttaaaaaaaa aaaaaaaaaa
//
