LOCUS       NM_001024205           10399 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nuclear FMR1 interacting protein 2 (Nufip2), mRNA.
ACCESSION   NM_001024205 XM_110931
VERSION     NM_001024205.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10399)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10399)
  AUTHORS   Rehage,N., Davydova,E., Conrad,C., Behrens,G., Maiser,A.,
            Stehklein,J.E., Brenner,S., Klein,J., Jeridi,A., Hoffmann,A.,
            Lee,E., Dianzani,U., Willemsen,R., Feederle,R., Reiche,K.,
            Hackermuller,J., Leonhardt,H., Sharma,S., Niessing,D. and
            Heissmeyer,V.
  TITLE     Binding of NUFIP2 to Roquin promotes recognition and regulation of
            ICOS mRNA
  JOURNAL   Nat Commun 9 (1), 299 (2018)
   PUBMED   29352114
  REMARK    GeneRIF: Binding of NUFIP2 to Roquin promotes recognition and
            regulation of ICOS mRNA.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10399)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   4  (bases 1 to 10399)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   5  (bases 1 to 10399)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   6  (bases 1 to 10399)
  AUTHORS   Bardoni,B., Castets,M., Huot,M.E., Schenck,A., Adinolfi,S.,
            Corbin,F., Pastore,A., Khandjian,E.W. and Mandel,J.L.
  TITLE     82-FIP, a novel FMRP (fragile X mental retardation protein)
            interacting protein, shows a cell cycle-dependent intracellular
            localization
  JOURNAL   Hum Mol Genet 12 (14), 1689-1698 (2003)
   PUBMED   12837692
REFERENCE   7  (bases 1 to 10399)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 10399)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591136.20.
            
            On Oct 3, 2009 this sequence version replaced NM_001024205.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030113.1, AK160601.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               AL591136.20        176723-177091
            370-2082            AL591136.20        182126-183838
            2083-2115           AL591136.20        196093-196125
            2116-10399          AL591136.20        200267-208550
FEATURES             Location/Qualifiers
     source          1..10399
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 46.74 cM"
     gene            1..10399
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="nuclear FMR1 interacting protein 2"
                     /db_xref="GeneID:68564"
                     /db_xref="MGI:MGI:1915814"
     exon            1..369
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..2168
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="82-FIP; FMRP-interacting protein 2; 82 kDa
                     FMRP-interacting protein; proliferation-inducing gene 1"
                     /codon_start=1
                     /product="FMR1-interacting protein NUFIP2"
                     /protein_id="NP_001019376.1"
                     /db_xref="CCDS:CCDS25083.1"
                     /db_xref="GeneID:68564"
                     /db_xref="MGI:MGI:1915814"
                     /translation="MEEKPGQPQPQHHHSHHHPHHHPQQQQQQQSHHHHHYYFYNHSH
                     NHHHHHHHQQPHQYLQHGAEGSPKAQPKPLKHEQKHTLQQHQETPKKKTGYGEINGNA
                     GEREISLKSLSSDEATNPISRVLNGNQQVVETSLKQTVKTSTFGKAGIKTKNFIQKNS
                     MDKKNGKSYENKSGETQAVDKTDTIAIPNGVITSSSGYITNGYMSKGADNDGSGSESG
                     YTTPKKRKARRNSAKGCENLNLVQDKIMQETSVPALKQGLETLKPDYSEQKGMRVDGS
                     KPIWKYETGPGGTSRGKPAMGDVLRKSSDIKPGLSSKKFDDRPKGKHASAAASKEDSW
                     TLFKPPPVFPVDNSSAKIVPKISYASKVKENLNKTVQNSSVSPSSSSSSSSTGETQTQ
                     SSSRLSQVPMSALKSVTSASFSNGPVLAGTDGSVYPSGGQPLLTTAANTLTPISTGTD
                     SVLQDMSLASAAVEQIKSSLFIYPSNMQTVLLSAQVDLPSQTDQQNLGDIFQNQWGLS
                     FINEPSAGPETVIGKSSDHKVMEVTFQGEYPATLVSQGAEIIPSGTEHPVFPKAYELE
                     KRTSPQVLGHILKPGTTESGALSLDPSHIGDLQKADTSSQGALVFLSKDYEIENQNPL
                     ASPTNTLLGSAKEQRYQRGLERNDSWGSFDLRAAIVYHTKEMESIWNLQKQDPKRIIT
                     YNEAMDSPDQ"
     exon            370..2082
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2115
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..10399
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3323..3328
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="hexamer: AATATA"
     polyA_site      3345
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="major polyA site"
     regulatory      5152..5157
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="hexamer: ATTAAA"
     polyA_site      5174
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="major polyA site"
     regulatory      8970..8975
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="hexamer: AATAAA"
     polyA_site      9001
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="major polyA site"
     regulatory      9139..9144
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="hexamer: AATAAA"
     polyA_site      9161
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
     regulatory      10380..10385
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="hexamer: AATAAA"
     polyA_site      10399
                     /gene="Nufip2"
                     /gene_synonym="1110001M19Rik; 9530056D24Rik; mKIAA1321;
                     PIG1"
                     /note="major polyA site"
ORIGIN      
        1 agatataccg agcgagcgcg gagaagcagt ctcagatcct gacggtgcag cagcccgcag
       61 cctcagccag ggagtcccag ccgctttcaa tggaggagaa gcccggccag ccacagcctc
      121 agcaccatca cagccaccac catccgcacc atcatcccca gcagcagcag cagcagcagt
      181 cgcaccacca ccaccattat tatttctaca accacagcca caaccaccac caccaccacc
      241 atcaccagca gcctcaccaa tacctgcagc atggagccga gggcagcccc aaggcccagc
      301 ccaagccgct gaaacatgag cagaaacaca ccctccagca gcaccaggaa acgccgaaga
      361 agaaaacagg ctatggtgaa ataaacggta atgctggaga aagagaaata tctttaaaga
      421 gcctcagttc tgatgaagct accaacccta tttccagggt ccttaatggc aaccagcaag
      481 ttgtagaaac aagcctgaag cagactgtaa agaccagcac ctttggaaaa gcaggaatca
      541 aaaccaagaa ttttattcag aaaaacagta tggacaaaaa gaatgggaag tcttatgaaa
      601 acaaatctgg agagacccag gctgtagata agaccgatac catagcaatt ccaaatggtg
      661 ttataacaag tagttcaggc tatattacta atggttatat gagcaaagga gcagataatg
      721 atggtagtgg atctgagagt ggatatacca ctcctaaaaa aaggaaagct aggcgcaata
      781 gtgccaaggg ttgtgaaaac cttaatttag tgcaggacaa aataatgcaa gagactagtg
      841 tcccagcatt aaaacaggga cttgaaactt taaagcctga ctatagtgaa caaaagggaa
      901 tgcgagtaga tggttcaaag cctatttgga aatatgaaac tggacctgga ggaacaagtc
      961 gtggaaaacc tgctatgggt gacgtgcttc gtaaaagctc tgatattaaa cctggtttga
     1021 gtagcaaaaa atttgatgat cggcctaaag gaaagcatgc ctcagctgct gcctccaaag
     1081 aggactcatg gaccttgttt aagccacccc cagtttttcc agtggacaat agcagtgcaa
     1141 aaatagttcc taaaataagt tatgcaagca aagttaagga aaacctcaac aaaactgtac
     1201 agaactcctc cgtgtcacca tcttcatctt catcatcatc atctactggg gaaactcaga
     1261 cccagtcttc aagtcggtta tcccaggtcc cgatgtcagc tctgaaatct gttacttctg
     1321 ccagtttttc taatgggcct gttttagcag gaactgatgg aagtgtgtac ccatctgggg
     1381 gtcagccact gctaacgact gctgctaata ctttaacacc catctctact gggactgatt
     1441 ctgttcttca ggacatgagt ctggcttcag cagccgttga acaaattaaa tctagccttt
     1501 ttatctaccc ttcaaatatg caaacagtgc tgttaagtgc acaagtagat ctgccctctc
     1561 agacagatca gcaaaacctg ggggatatct tccagaatca atggggttta tcatttataa
     1621 atgagcccag tgctggccca gagactgtta ttggaaagtc atcagatcat aaagtgatgg
     1681 aagtgacatt tcaaggagaa tatcctgcca ctttggtttc acagggtgct gaaataattc
     1741 cctcaggaac tgagcatcct gtgtttccca aggcttatga gctggaaaaa cggactagtc
     1801 ctcaagttct gggtcacatt ctaaaacctg ggactactga gagtggagcc ttatccttgg
     1861 accccagtca tataggtgac ctgcaaaaag cagacaccag tagtcaaggt gctttagtgt
     1921 ttctctcaaa ggactacgaa atagaaaatc aaaatcccct ggcctctcct acgaacactt
     1981 tgttaggctc cgccaaagaa cagagatacc agagaggcct agaaaggaat gatagctggg
     2041 gttcttttga cctgagggct gctattgtat atcacactaa agaaatggaa tctatatgga
     2101 atttgcagaa gcaagatccc aaaaggataa tcacttacaa tgaagccatg gatagtccag
     2161 atcaatgaag gaccagactg cctatttgta atctttctgc agcattagag ccaccgttca
     2221 tgtgggacac aaggctttta tgctcctaga tcttcaacgc agcagaggaa ccataagtag
     2281 aatcacagga taatatatac aaatatatat atatatatac atatatatat atagttattt
     2341 aaaaaaaggc aactgaaagt aattagactt cttaaggaat caaatttatt tcaagagact
     2401 acacatggtt atttaatctc cggtactgaa tagtcctttt ctttattatt ttgttagttt
     2461 ttgtttttaa gtgtgaatgc aagtgattaa tgaatacaga cttaacaagc gtggttctaa
     2521 agttcctgct gtcatctact tgggcaacaa atgacccact ggaaaggcaa atccacttac
     2581 ttctaggtat ctgtaccttg ttctgtgact aaagtgatac actaatcacg gggaacccag
     2641 aatgattcaa cattttcccc tactccaccc ttgatctttt agttttgagc cctgcgagaa
     2701 tgctggataa atgccttgaa gtttgcaggg atgttttttg ttgtttgttt tttgttggtt
     2761 tttttttgtt tgttttaata caatgatttg catgtcttgc caagagttct gcagcctatg
     2821 tggggtgttg gggaaatagt tcctttcctt ttattttttg ttgggtgggg acagggggag
     2881 ggcattgaag ttctacaatc ctggaatagt ttgtgggtat atagttaact tactttggtt
     2941 acatgtttgg acttttaaca tctaagagtg tcattcaaaa aaaagttgca gaacaagtaa
     3001 ttggctgata attacccatt gtaattgtgt aactgggagc aaaaatatat tctgcttttc
     3061 tgctgtaggt gctctgactt gctctctgtc actaacacta agtgtatact cttgtttttc
     3121 atcaaccatt taagagaaac gtatgtacct ttctgtaaat tcttttaatt tcagtttctc
     3181 agcaaaatcg aaaaaagaaa aaaaaaatta atgaaaactg tcttgttttt ttagccagtg
     3241 aggaggtaat aaatcctgat tgtagaaggt gtgttttcag gcaaattctg cttctgagct
     3301 tacttgtttc tgattatatc ttaatatatt ttatcattag agcaagattg ggttcctttg
     3361 gttatttttt tctttctttc tttctttttt ttttttttta agaaaaataa tgtgaaattc
     3421 tgaattttgt tttgggcaga aagagcatta gccctgtctt atcatcgcat taccatcctg
     3481 ttgtgctgca gcttgtgtat agcatgcgcg cgcgtgtctg tgtgtctgtg tctgtgtgtg
     3541 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tagaaacgaa
     3601 gggtccaata taagactggg tgatgttagt ggcataaaaa caagttctct ggcctgatgt
     3661 agcaacacat cacacacata acacatacag agaaatcaat gtatccatgt atgtcaaata
     3721 caagttaaac tagcagggca tttatacagt tgcagtcttc taacaaaggc aaactggatc
     3781 ccctagacac ttttggggga gaaagtagtt actttttact cttgttttct aagaaatgtc
     3841 cagttttgag cgattgtagt gtggatggat tttctggttt tgttaactat ttcaggtttt
     3901 taacaaatgt tcatgaaaga agctatttga tttactgcag agaaaaatac tttttagtct
     3961 ggatttctgc cctgcttaga tttttttttt ttaagtataa gcatggattg ccaattccac
     4021 ttgatgtaaa caaaactttt tatacataat atatataata acttattgta tcagtccagg
     4081 ttcagaaact tgtggtaggc cagtttcaga tagtttcatt tcacctgtaa actgtatcac
     4141 ttttactgat attgtaattt tcaaatgtat aatatgttta cagatgtgcc ctgcatttag
     4201 tcgctttgtt cctattttga ttttttgttt ttgttgtttg tttttgttgt tgagtctcct
     4261 gcctgcttgc caaaagctag gatgcttcag gccggtgtac atcagtgagg catccttgag
     4321 ctttaaagca ttgaacaaac tggaaaatgc aacacgccac atattgaact gagtctgtgt
     4381 tttgtgttct tttttttttt ttttaataaa aattttcaga aaatttaaaa aaaaaatctt
     4441 gattaaagaa aaacgaggct ccagtttgtt ttataggttt taaagttctg ctgtgtgttt
     4501 aattgccttg tgtgaccact tgtcgcctta gggctgaatc cttaccccac ttttttttaa
     4561 atgtccattt tgcttgcctg gaatttaaaa gttcttctgt tgcacaaatc acaaaaacaa
     4621 aacaaaaata tatttccttg gtttatgtcg tacaaggttg aatgaacata gtcaaaatga
     4681 aaagaaaatt ctagtttcct gaattgggat tttttaactt agaagtaata cttagtacct
     4741 ttaaggcctt cactttcata gttccttttc cataacttca ggcctctgca aaggagctaa
     4801 agagagttta tttctccttc tctgtccaag gcttgagaat ctcacttctt ctaaatgaaa
     4861 caatgcaaca tttcactttg atttgtccac tgaaattttc tcaatgtggt tagaggtata
     4921 tatatatata tacatatata tatatatata tatagtagtt agaaatgtct cttaactttc
     4981 tgggatccct agtggcccat catattaact gtcagtattt tttggacatt gggttaatgg
     5041 acttaattgc ctcagtacga gcaggacttt gggacagata tcttttgtgc tgtttgatac
     5101 ttgtctcaat ctttctcctt aggtcctcac acaattcctt acagagcact tattaaaaaa
     5161 gtcttacgag ttcatctgtt ttctgatttt ttgtgtgtgt gtgtaagctt ctaaaagaaa
     5221 tatcagttgt gatttaattt agcacattta aataacaata tgttggtata aagaattttc
     5281 cttcaactca gagtattagt actgtagcat aaaccaaata cagtctagag gggattttta
     5341 acatccctcc atttaaaaga ctgaaaaaag atgtgtgtgt gtggatgtat gtattttggg
     5401 atgcttgtat gttggggaaa gatgaagata ctaagaaata gtaaatgaat gtgtaagaca
     5461 ttatattagt attcagagaa tgaaacttgt atttattttg tgccatttgt tttcattaca
     5521 tgggataaag tcaggtagtt taaatccttc aagggtagta ctagaaaaat ggcactacgg
     5581 atgaaatcat gacctatttt tttaatggct aagaaactaa ttatgggtga tgatttcctt
     5641 ttcagttcgt cttgattgta ggttttatgt cacacaccac tcaattttgt ggaaaagtct
     5701 tgaataatct cccttcctca caaaagacag ggtgtattta tcttttctcc attctcactt
     5761 caacaacctg aagttaattg catagtattt cctctaacct tagtagtgaa ccttcacatc
     5821 aataaagttt ttatggtgtc tatagtagcc tgcccttctc tactttctag gaggggataa
     5881 ccaatatcta aaaacttggt agtgacacct tctccccccc cccccatcct ccacccgatt
     5941 tcctagttac cactcaatct gcaattgttt caaatgacag tttgtggaga aaataaggca
     6001 aacctcaatt gatagggcag tttcttcaca aaattggaca tgtcagcagt agctgaacac
     6061 ttggtagact tgttgccagc cttcaccaaa agcttttttt ttttgaggtc agtgaaaagg
     6121 catgtaatgt gaacttgaac tagatgggca catgcaaagg atattgaaga cttggctcaa
     6181 tttaaaaacc tgtctaaata ggtggtggta aggtgtctct caacttactt agtgtgcaga
     6241 agggtttgat accacttcac catattttaa aaatacacgc ctccttttat atattaacca
     6301 accgaactag taatgtagtg ggccaaatat gtgaacaaaa aattctgtga tgtttgcctg
     6361 ccagagtgga ctttgatagg actgtattaa gatgggactt atttccccgg cttctagaag
     6421 cttggtagga aagcacagga caagagtaaa agtcaaagta gctgcttaaa ggtggccaga
     6481 agaacacatg gcctgacaag tcactgattt ttctctttgg caccagtaga cttctgtgtt
     6541 gaaggtgggc ttctgctgtg ggtatcttaa aatgcttatg aacacttagc tatatatgtc
     6601 agtgagtggc aaggctattc tggtcgtgta aagaatgata tcattaactc cactcaagaa
     6661 ctgatctact gagttttaag aaaggtctta aagcagttaa tgccagcagt agttgagttt
     6721 taagttctcc atcataaaat gcccagcaaa gcagcagtag tgtaatacta ttctattatg
     6781 aggactgtca aatatggatt agaaactcaa aagacaccct aaactgtagt gggattgctg
     6841 gtttaaacat ttcctattta gaacattttg ttctgaagtc ataacaatta gatgtctgaa
     6901 tttttttgtt tgtttttttt gttttgtttt gttttttgtt ttttggtttt tttttttttt
     6961 tttacttttt tttaggtggg gtgggggatg ttgttacagg gtttctcagt gtagtactga
     7021 ctggcctgga acttgctctg tatactaggc tggcttggaa cttagatctg cctgcctctg
     7081 cctccgattg ccaccaagcc tggcaatgtc tgttatttaa cagccttatt tgaaatagtt
     7141 agaattgttt cccccagttc agtttggctt tccttgtaat ctgttttaat cttcagacca
     7201 aacaacttag attaacatta caatagcttt ctgtatatat atcccctttc ctcaggtgct
     7261 aaacaaaggc tccaaaatga atactgcttt agtaacatct cttattaaaa tgcacatttc
     7321 ttttactaat tgtaaagatt tggtgttaac aaaatggttt taatatgtaa atatgaacaa
     7381 ataccttaag ttctacttgt ctattaagtg tgtttgcatt tatcttttgt agataatttt
     7441 tcacaatctt taatacattt cattaggtat tattgcatct ttagaatgaa aacaactgtt
     7501 ttgtcttaga ttacgcctgc tgctgctgct gctatgggaa actgagaaat caagaatgtg
     7561 atgcactttt taaacattac tatataccat aggttgcgtt aatacctttt tttttttttt
     7621 ttttttttgg tagcacagcc actaacaaaa atgaacagag tttaatattc tcttcaggtg
     7681 tgagtagtaa agtagtctgt agtttgtgtt gatttatgaa ggggacaata acttagaagt
     7741 aaatttttgg ttaatattat attttggcct taaaatgtct tctactactg aaaatatttt
     7801 aaatcatagc tttgtttcta ttccctctgc ttcaaaaaga cttgggaagg attagaggaa
     7861 gtcatttcat tgttttcttt ttagttgtca gtaagctggg ttttttatta catttatttc
     7921 agagaagtaa tgctacccta aaccaatcat acctagttta gttaacaagc tcccaactat
     7981 tccacttctc tagtatatat tcaaagataa acaaggtgta agaatgcaac ttgacaaagg
     8041 aaaaatatct ttgcaagcac atactcaaag atgaaggagg aaaagtatag aggaaggaca
     8101 ccaaatgagg tggaggaata tgagaatgat gtgtggtcca aagctatctg gttatatttt
     8161 gatgttgcca atattgcaga gccaaatttt taatttgctt actaatatat ttgttggcca
     8221 gagatctatt tttatatcag tgtgccttgc atgtatatta actttggaaa ggccatgtag
     8281 taaatgcctg agatgttgat ggttcttacc acctcactga tttttatgca gttgaaatgt
     8341 tcattctatt gcccaactgg tgctctctgt ttaaagttat agatcttgtc aaactggaac
     8401 tcttttataa actggggaag tgacttgttt tttcactaat ccccctaccc ccatagtctg
     8461 ttagtggctg gtctgtaggg aaatagtaaa aattattcac tacctacccc tacccttaac
     8521 accaccttca agtaatgtga taataccatt tctttgtgcg ctttgaaaaa agtttcagct
     8581 tgctgcctcc tttagtgtta tgaaaggtat tattaaaagc attgtttgca aaaatgcagg
     8641 aagatgatgg atgtccacat taatttggga ttctttgtga gctttaattc aagttattgg
     8701 ctcattccaa caattttatt gttgaagcac cttgcttagg aatttttaaa tattcatgtc
     8761 tgcaacactt gtctcaaaat aaattgtgca attcttgtca aaaaacagta aacaaaaaca
     8821 gatctgaact ctccctattg tgacttgtta gtttctgtat tttctgccag tgtaaatgtg
     8881 aaaagctttg cttgcattac gttttagaaa tgcattttgc acactcagtt ttgccgaagc
     8941 tccatgaaaa ggttagattt aagtagatga ataaagctat gcacatgttt tgaaagttta
     9001 atttgtgtgt cattaccaaa agtaatctgt cattattttg ctgttcttag ctttaccatc
     9061 tttggaaaca tggttcaaag ttataatctg ggctagctca tcagtggaac taaaatgaag
     9121 gaaaactggc acccactgaa taaagttgaa ttgtaatgag agcctgactt gtatctgtta
     9181 aagggctttt cttcaacagg acagttgtat cagctttata aaccattgga cccaatgttc
     9241 ttctcagtga aattttaaat atttatgaaa aagaaatgga aagtcattca aactgaaatg
     9301 aaggatagac ctttgccata tgaagctctg acaattttat gtcttaagtc tggtttaaag
     9361 ttaggatagc ctttttatta acctttattt taacatgaat ttgattaact ggatgatttg
     9421 aaattaaagt cattaagttt aaagggcaaa gcacaagatt gttttaaaga tatattgaaa
     9481 agcccaagtt gatctgagca agttcatgat ctgggcgtgt ttggttaatt caccgcagtt
     9541 gcatgttcta agtagtttca cttacttgaa gtgtgcactc acaaagttgt gtagatgtgc
     9601 tggccagatc ttgtcattca tcttctaata gatagctttg ctcatttcct ttaggacatt
     9661 tgtagacgag tagaagatat tatcaatggt gttttcccca ggctcccaga tacaagatat
     9721 atttcatttt atagctttgt ctagtaaaga ttcttcaaaa tatggttaat gatgcataac
     9781 cttataaaca caggtagtag cgaacagctt ggatggcttt ggctgctctt gaatatctgt
     9841 cattagtttg attcacatct tagttgatta cacttgtaat cctggcaacc agaaggctga
     9901 agcaagcgga ttgagtccaa agccagactg gcctgcatgg caacaacata gtgtattgga
     9961 gaagtaaagt aatctattgt gtgcagattt atttatgagc tgggttgcct tttaattttg
    10021 gaaaaggaga attactgcat tatagttaga agatgttggc ccttttcctg ctgaaatttt
    10081 tttcaatact tgttttgccc agtttaaaaa ataataaaag taggtctttt ttagatagaa
    10141 cagtgaccag aagtttattg ttttgctaaa taactgactg cttagttata ctaaagctgt
    10201 tgatgttatg gattccaagg aagtgtcagt tacatgatga tctttcttta tcaatgtctt
    10261 acttaatgtt cagtgtttta aaaatacaga attacactcc acaaccatac tcagatttac
    10321 ttattttatc agaaaaactt gagatttgta gatcaaataa gacaattaag tgtacattga
    10381 ataaaaaagt ttaaaagtt
//
