LOCUS       NM_013745               3974 bp    mRNA    linear   ROD 06-AUG-2023
DEFINITION  Mus musculus nuclear FMR1 interacting protein 1 (Nufip1), mRNA.
ACCESSION   NM_013745
VERSION     NM_013745.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3974)
  AUTHORS   Yuan M, Tu B, Li H, Pang H, Zhang N, Fan M, Bai J, Wang W, Shu Z,
            DuFort CC, Huo S, Zhai J, Yao K, Wang L, Ying H, Zhu WG, Fu D, Hu Z
            and Zhao Y.
  TITLE     Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to
            secrete nucleosides and support pancreatic tumor growth
  JOURNAL   Nat Cancer 3 (8), 945-960 (2022)
   PUBMED   35982178
REFERENCE   2  (bases 1 to 3974)
  AUTHORS   Bardoni B, Willemsen R, Weiler IJ, Schenck A, Severijnen LA,
            Hindelang C, Lalli E and Mandel JL.
  TITLE     NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic
            shuttling protein associated with active synaptoneurosomes
  JOURNAL   Exp Cell Res 289 (1), 95-107 (2003)
   PUBMED   12941608
REFERENCE   3  (bases 1 to 3974)
  AUTHORS   Bardoni B, Schenck A and Mandel JL.
  TITLE     A novel RNA-binding nuclear protein that interacts with the fragile
            X mental retardation (FMR1) protein
  JOURNAL   Hum Mol Genet 8 (13), 2557-2566 (1999)
   PUBMED   10556305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125128.3.
            
            [WARNING] On Sep 29, 2023 this sequence was replaced by
            NM_013745.6.
            
            On Oct 19, 2007 this sequence version replaced NM_013745.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032324.1, BC020364.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-436               AC125128.3         110006-110441       c
            437-510             AC125128.3         109335-109408       c
            511-609             AC125128.3         107059-107157       c
            610-672             AC125128.3         106292-106354       c
            673-749             AC125128.3         105472-105548       c
            750-842             AC125128.3         96754-96846         c
            843-1036            AC125128.3         95001-95194         c
            1037-1153           AC125128.3         90403-90519         c
            1154-1380           AC125128.3         88134-88360         c
            1381-3974           AC125128.3         83953-86546         c
FEATURES             Location/Qualifiers
     source          1..3974
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.35 cM"
     gene            1..3974
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /note="nuclear FMR1 interacting protein 1"
                     /db_xref="GeneID:27275"
                     /db_xref="MGI:MGI:1351474"
     exon            1..436
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..1497
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /note="nuclear FMRP-interacting protein 1"
                     /codon_start=1
                     /product="FMR1-interacting protein NUFIP1"
                     /protein_id="NP_038773.1"
                     /db_xref="CCDS:CCDS27284.1"
                     /db_xref="GeneID:27275"
                     /db_xref="MGI:MGI:1351474"
                     /translation="MAEPAPAVWPSAPDLTPAPGTPSEAAPPRDNWVYWAMLPPPPPP
                     LSSPVAGSEQSRKGQPHVLPQPPSGALPPFDAQILPAAQPPFDAQAPPDAQSQFSGQQ
                     AWNLQASTPWYWGLSPNGFSTYHTSYQSPVTHSYFPRSHDAKFNLPQNRKQKTKKRKE
                     PVFHFFCDTCDRGFKNQEKYDTHMSEHTKCPEVDCSFSAHEKIVQFHWRNMHAPGMKK
                     IKLDTPEEIARWREERRKNYPTLANIERKKKLQLEKAKRGEVLTTTQYGKMKGMSRHS
                     QMAKIRSPGKHHKWRRGGARQRAVVGLGNHARDSKPEVPSKANVDPLGALIHSDSESD
                     KEEKAQRTVVPKEVTPALCSLMSSYGDVSGSDSEPEEAPIKTEAEVLAENHVLHSSPP
                     KSPKQNVQTTGRTVSRSKWENQRNGLRKISLKRKKSHCHPLFEPRTHHPYLLEMLLAP
                     DIRHERNVILQCVRYIIKKDFFGLNTDSVKTEEV"
     exon            437..510
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            511..609
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            610..672
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            673..749
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            750..842
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            843..1036
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1153
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1380
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..3974
                     /gene="Nufip1"
                     /gene_synonym="Nufip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttccacag ttgcactttg ggctcgctgc ttgctaggtg gcatggctga accggcaccc
       61 gccgtgtggc cttcggcccc ggatctgact cccgcgcccg ggactccgag cgaagctgcg
      121 ccgccgcggg acaactgggt gtactgggcc atgctgccgc cgccaccacc tcctctgtcg
      181 tccccagtgg cgggctcgga gcagagccgg aagggacagc ctcacgtgct gccccagcct
      241 ccctccggag cgcttccacc gttcgatgct cagattcttc ccgcggcgca gcctcctttc
      301 gatgcccagg ctccgcccga tgctcaatct cagttcagcg gccagcaggc ctggaatttg
      361 caagcctcca cgccttggta ctggggattg tctcctaatg gtttttccac gtaccacacg
      421 tcttaccaat ctccggttac acattcttat tttccacgat cacatgatgc aaaattcaat
      481 ttgcctcaaa acagaaaaca gaaaacgaag aaaagaaagg aaccggtttt ccattttttc
      541 tgtgatacct gtgatcgtgg ctttaaaaat caagaaaagt atgacacaca catgtctgaa
      601 catacaaaat gccctgaagt agattgctcc tttagtgcac atgagaagat tgtccagttc
      661 cattggagaa atatgcatgc tcctggtatg aagaagatca agctagacac tccagaggag
      721 attgcaagat ggagggaaga gagacgaaaa aactacccaa ctctggccaa tattgaaagg
      781 aagaaaaagt tacaactgga aaaggcaaag agaggagaag tgttgacaac cacacagtat
      841 ggcaaaatga agggcatgtc cagacattca cagatggcaa agatcagaag tcctggtaaa
      901 catcataaat ggagaagagg tggggctagg cagagagcag tcgttggact aggaaatcat
      961 gccagagatt cgaagcctga agttccatcc aaggctaatg tggaccctct aggtgctttg
     1021 atccacagcg actctgagtc tgataaggaa gagaaagcgc aaaggactgt agtgcccaag
     1081 gaagtgacac cagccttgtg ttcgctgatg agcagctacg gcgatgtctc ggggtcagac
     1141 agtgagccag aagaagctcc catcaagact gaagcagaag ttctggcaga aaaccatgtt
     1201 cttcatagca gtcctcccaa gagtccaaaa caaaatgttc aaacaactgg tagaacagtc
     1261 tcaagatcca agtgggagaa ccagaggaac ggactcagaa agataagcct taagcggaaa
     1321 aagagccact gtcacccatt atttgaacca agaacacatc acccatatct cctggaaatg
     1381 cttctagctc cagatattcg acatgaaaga aatgtgattt tgcagtgtgt tcgatatatc
     1441 atcaaaaaag acttttttgg acttaatact gattctgtga aaactgaaga agtgtagatg
     1501 tctcccgttt ccacactcat ctgtaaagca cctgagagaa caccatcctt gagtaaggag
     1561 agaaaatcag caacttctgc agctgggatc agtaattgaa ctggaagcct catgggcgtc
     1621 atgttggatt ttaagtctgt cctcaggctt tatgcaaata aatgcatagc tggtcttttt
     1681 tacatagtgt gtctgtgtca ttggggggtg ggaggtaact gagtaggctt tttttttttt
     1741 ttaaagagat ttgtttatgt atcagtgctt tctctgcatg tacacttgtg tgccagaaga
     1801 gggcatcaga tcttatagat ggttgtgagc caccatgtgg ttaccgggat ttgaactcag
     1861 gacctctgga agggtagcca gtgctcttaa ccgctgagcc atctctccag gccccgctga
     1921 atggggttct taagctttcc actagtgacc tccttttgtc caaggaatct ctgtatgacc
     1981 ccaggcttag ataagtaaca agacaggtat acaaatcaaa cgtcactggt agacaggtat
     2041 acaaatcaaa cgtcactggt agacaggtat acaaatcaaa cgtcactggt agacaggtat
     2101 acaaatcaaa tgtcactggt agactggtat acaaatcaaa cgttactgat agaaagccgt
     2161 aaaggaaatg actttaatat aattctttgg tgtgcatata atttcattta ttaaagagaa
     2221 gcatatttgc ataccaatca ggtgaatgat cctgtttcgt ttttttcatt taagaattac
     2281 atcttggctg aggttgatgt tgcaggacgt agaacatctt cagacttttc cagagttgac
     2341 tgattttgta attgttaatg ttgaaacact gcttttgtat aagtatgtat tgcaaaatgg
     2401 cagaataatg taagatgcca ttttagaaat tgatggaaat tctgtcctaa tctcaagcca
     2461 aaattataag gagttttgtt ttgttttgtt ttgttttttg atgctcaagt cagcagtgca
     2521 aacagcagtt tttaaaatca aacaccatgg agcctaatca tacactgatt tgatatgaac
     2581 gtgtgaagca tagcaagagg caaatattac aagtcttggt tttctatagc caaaccgtga
     2641 gagcagaaga cgacgtcgta agagaggctg cagttcacag acctacagct gtctggagtc
     2701 tgagcttagg tttgaggtgc catttgtagt gtgatggtag gcgcagtgcg gagtgtgtgc
     2761 tcaggcttaa agccacagcg aagtcacagg acacagcccc agcgtgtgca gccagaatca
     2821 ctttagattc attgcacatt ggattttgaa ttgacttgtg gtcattgtgc atttctgcct
     2881 tttactgttg ccacgcagtt gcacacatcc acagttgaag aagctggctg tgtagcattt
     2941 gctgggaata ccttatttat ttatttattt atttatttat ttatttattt tccatattgc
     3001 tgtcatgtaa ggaaggaaga ctgtggttga gttaattaag agttgaagat actgggtaat
     3061 agggaaagct ttttaaaatg cttgatttag ccagatatat ataagggaga tatattttgt
     3121 ttcaattcaa gagttattta acagtgacca agggtagtat tttaaagagg ctcagtgggt
     3181 agagcacttt acacacaagc ctgacaccga gttctgtctc aaaaacccta cataaaaatg
     3241 gagagagcca actccacaga gttgtaccct tgacctccat gactgctctg tctgtctgtc
     3301 tctgtctctc acacacacaa acatacatat gtgcacgcac acacatgtgt acacactcat
     3361 tatacacaaa tacatatata cacacatgta tacaacacaa cacatgtatg caaacctatg
     3421 atgattgtga tggtttgtat atgcttggcc cagggaatgg cactgttagg aggtatagcc
     3481 ctgttagagt aggtgtgtcg ctgtgggctg ggctttagac actagctgcc tggaagggag
     3541 tcttctctta gaggcctaca gatgaagatg tagagctttc agcaattcct gcagcatgcc
     3601 tgcctggatg ctgccatgct cccaccttta ttgttgggag cgaccctgtt tgttaactgc
     3661 ctcgtcagcc gtaagtgctt actcacaaag ctttggcctt agtggacgag tactagctta
     3721 gagattaata tgagatttct gtgggaagaa gttgaggcct ctgtgggaaa gtactacccc
     3781 cagttaagaa caggtaccta gcaacccatt ctgttctgtt tcccctgctg actttttacc
     3841 aatatcctgc ttttgggaac aggtgtgttt cccccagaaa caaagcgatt ctgcatcacc
     3901 cccctcccca tatcctgctt ctgtgggcat aaaacctgcc tgggaataat aaaaatttga
     3961 cagcttgatc aatc
//
