LOCUS       NM_173748               3688 bp    mRNA    linear   ROD 08-AUG-2024
DEFINITION  Mus musculus NudC domain containing 3 (Nudcd3), transcript variant
            1, mRNA.
ACCESSION   NM_173748
VERSION     NM_173748.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3688)
  AUTHORS   Chen,R., Lukianova,E., van der Loeff,I.S., Spegarova,J.S.,
            Willet,J.D.P., James,K.D., Ryder,E.J., Griffin,H., IJspeert,H.,
            Gajbhiye,A., Lamoliatte,F., Marin-Rubio,J.L., Woodbine,L.,
            Lemos,H., Swan,D.J., Pintar,V., Sayes,K., Ruiz-Morales,E.R.,
            Eastham,S., Dixon,D., Prete,M., Prigmore,E., Jeggo,P., Boyes,J.,
            Mellor,A., Huang,L., van der Burg,M., Engelhardt,K.R.,
            Stray-Pedersen,A., Erichsen,H.C., Gennery,A.R., Trost,M.,
            Adams,D.J., Anderson,G., Lorenc,A., Trynka,G. and Hambleton,S.
  TITLE     NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and
            Omenn syndrome
  JOURNAL   Sci Immunol 9 (95), eade5705 (2024)
   PUBMED   38787962
REFERENCE   2  (bases 1 to 3688)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3688)
  AUTHORS   Yang,J., Xu,J., Zhang,L., Li,Y. and Chen,M.
  TITLE     Identifying key m6A-methylated lncRNAs and genes associated with
            neural tube defects via integrative MeRIP and RNA sequencing
            analyses
  JOURNAL   Front Genet 13, 974357 (2022)
   PUBMED   36482889
  REMARK    Erratum:[Front Genet. 2023 Jul 10;14:1198975. doi:
            10.3389/fgene.2023.1198975. PMID: 37496715]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3688)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (bases 1 to 3688)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL607152.21 and AL611926.12.
            
            On Mar 30, 2023 this sequence version replaced NM_173748.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK049739.1, BC052089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-248               AL607152.21        7158-7405           c
            249-571             AL611926.12        134761-135083       c
            572-704             AL611926.12        92102-92234         c
            705-848             AL611926.12        67025-67168         c
            849-1037            AL611926.12        54850-55038         c
            1038-3688           AL611926.12        47312-49962         c
FEATURES             Location/Qualifiers
     source          1..3688
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.91 cM"
     gene            1..3688
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="NudC domain containing 3"
                     /db_xref="GeneID:209586"
                     /db_xref="MGI:MGI:2144158"
     exon            1..248
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            249..571
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            572..704
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            705..848
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1037
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..3688
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3389..3394
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="hexamer: AATAAA"
     polyA_site      3408
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="major polyA site"
     regulatory      3666..3671
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="hexamer: ATTAAA"
     polyA_site      3688
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
ORIGIN      
        1 aatcagccgg tgtgaggcgg tgcccactgt gttcgcgtcc ctcgggcagc agagccatgg
       61 agcccggggc tgctgagctt tatgaccagg ccctgttggg catcctgcag cacgtgggca
      121 atgtccagga ctttctgcgc gtgctcttcg gctttctcta ccgcaagacc gacttctacc
      181 gcctgctgcg ccacccttcg gaccgcatgg gcttcccgcc cggggccgca caggccctgg
      241 tgctgcaggt ctttaaaaca tttgatcaca tggcccgcca ggatgatgag aaaaggaaga
      301 aagaactaga agagaaaata agaaaaaagg aggaagaggc caaggccttg ccagctgctg
      361 aaactgagaa ggtagcggtg ccggtcccag tgcaggaggt agagatcgat gctgctgcag
      421 acttgagtgg gcctcaggaa gtagagaagg aggagccccc aggctcccag gaccccgagc
      481 acacagtgac ccatggcctg gagaaggcgg aagctccagg aacagttagc agtgctgctg
      541 aaggccctaa ggaccctcct gtgctcccca ggattcagga gcagttccag aaaaatcctg
      601 acagttacaa cggtgccatc cgtgagaact acatctggtc gcaagactac accgacctgg
      661 aggtcagggt gcccgtgccc aagcatgtga tgaaggggaa gcaggtctct gtggccctta
      721 gcagtggcac catccgagtg gccatggtgg aagagaatgg agagcgtgtc ctcatggagg
      781 ggaagctcac tcacaagatc aacaccgaga gctccctctg gagccttgag cccggcaggt
      841 gtgttttggt gaatctgagc aaggttggcg agtactggtg gagtgccatc ctggaggggg
      901 aagagcccat cgacatcgac aagatcaaca aggagcgctc catggctact gtggatgagg
      961 aggagcaggc agtcctggac agactcacct ttgactacca ccagaaactg cagggcaagc
     1021 cccagagcca cgagctgaaa gtccatgaga tgctgaagaa ggggtgggat gctgaaggct
     1081 ctcccttccg aggccagcga ttcgacccag ccatgttcaa catctcccca ggggctgtgc
     1141 agttttaatg accggaagta aaggaaaccc tcgccattgg ggagatggag acgttgtcct
     1201 cctcactccc tgcatgccag ggactcactt ctcctgatca gtcctagcca tttttttctt
     1261 tcatgatgaa ccaggccttc catgctgacc ttctaccttc agactattct agagaaggta
     1321 cagggccagc tgctgcttgg cagtgtctgt ggccaacact gaatgcaggt gtttgacatg
     1381 caggagggac atgtcccagc ctactggtag cacatgttct gtctccacag caaccaggca
     1441 ctgcaggcag catttccttt ctccccgttc tctctgcttg ctgttgtttt gacgctattc
     1501 tgcttgcttg tcttctgatt ggggataagg agtggctggg ctcagacaaa gctaagttgt
     1561 tgtgtggagc caggcacctg catgagggcc agcggggcat ggctgtgggg ctgctatggg
     1621 gttccctcac ttgttgttga tctgtgtcta tctctgtgtg tgtgtgtgtg tgtgtgtgtg
     1681 ccatcttgct catttctttg tgaatacact tgacttgcct cagttttatg ggcagagcag
     1741 caggaactgg gtctgtttga gatggtagga gaaagtctga ggttctggcc tctcacccag
     1801 gtgtggtaag gattctgtct gccctctgac tgcagctgcc ttgctttgat tcttgttgaa
     1861 atgagctgag actagccacc actacttttt cccctcaaga cctcctcttt gggggtgctg
     1921 cattcaagcc tgggtacctc caagaagaga tcacagcctg ttggtagttc attggcagat
     1981 ccgtgtcaac tacactccct aaggagcttt gaccctgaag catgcctcag gaaggaaaac
     2041 gtatgcacta gcttgaaggc aactacaatt gagtccaaga aaatgaagat ttctctgtgc
     2101 caatcactag actgcttttt ggagctcaga gcctgtgtgg cgacgccagc taagggtgtg
     2161 aagacctgcc cagaggacca ggaccctggt gtcccatccc tttacgtact ctctctgtgc
     2221 tggttggtgc ctggcatctc catttgcctg gttcttagtt gtgtggtgtg tgtgtgtgtg
     2281 tgttcacgtc acagcactaa tttctatact ctggtaacca accatacaaa gtgcaagaat
     2341 taagacccat tgaagccaag gcagactgtt ctctggaaag agccctgcac caccgagtgc
     2401 tatgtccact tgcttggaag gagccattgg aagagcaaat tttggaactt acacaattgt
     2461 gtagaaagga gctggttcat tgtaggcatt taagggattt ctggtttact tcctaaaagt
     2521 ccatactggg agttaatctg tgggcctgag tagaccatga tggtggtcaa gggacagcag
     2581 tggaccccat atacccactc cagagtctga acatgtgatt ggacattggt catcaagttg
     2641 atgaaatctc cctcaagagg tcaccgtcca ggagcagaat ctgtcgtagt cacaagatcc
     2701 ccaggacact ttgctgtttg ttcctgaagt tttcatcaag gtctaggctg cgcacatccc
     2761 tgtcccatgg aagctgtctc acctaaagaa ggaagtctcg tggtgtgtgt gcacctgcag
     2821 tcttctccct ctcggccctc atcctgtggg tagtcttgca gaaggaatga tgtcgtggcg
     2881 gaaccctgca tccttttatt taagacaatg cttttctctg tgttgactca tcttcattac
     2941 tgtagcatgg ttttattttc tgtgttgcat ttttttcttt gtccctgccg tgtttcaaca
     3001 aacaagcctg tatagaaaaa gcagcctggg ggatatagca ctggttgtag gccgtggggc
     3061 aggaagctgt gactgatccc tggggcatgt tgtagtacat ggtgtagtgg tggcttctgt
     3121 atctacatgt ctccatcaca gtgaggctca atcccagcca gccaagtaga tagttctttg
     3181 ccctgaggca ctgccctggt ttgccccgcc actgaagctg gcacattgcc tgttttctct
     3241 ttttagacac gacagccaca gtgtggtctc taagtcccac cagctgaggt ctgaggaaag
     3301 cagggtgact ctgtcccctt tgcccagaga cccaaagagt ggggtgtcca gcctgcagag
     3361 ttgctctggc tcctcggtgt tggtttgcaa taaatctgtg tttaagcagt tctggttctg
     3421 tctgtgacag tcactattaa gacacttaca tgagtggtcg ttacccttga cttctagccg
     3481 tgagtcctgc ttccctctac acagtcaaca ccaaaactaa atgcactggg ttgtttctca
     3541 cctggccttt cactgctttt agaaatccta taagatgtta attttttatt gttaccataa
     3601 agacccattc aaaatattga accaccctgc tggagacccc ttttcttggg gttactattg
     3661 ccttgattaa acaccatgac caaaagta
//
