LOCUS       NM_011955               2139 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus nucleotide binding protein 1 (Nubp1), transcript
            variant 1, mRNA.
ACCESSION   NM_011955
VERSION     NM_011955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Zhao,Y., Zhang,M., Liu,J., Hu,X., Sun,Y., Huang,X., Li,J. and
            Lei,L.
  TITLE     Nr5a2 ensures inner cell mass formation in mouse blastocyst
  JOURNAL   Cell Rep 43 (3), 113840 (2024)
   PUBMED   38386558
  REMARK    GeneRIF: Nr5a2 ensures inner cell mass formation in mouse
            blastocyst.
REFERENCE   2  (bases 1 to 2139)
  AUTHORS   Ververis,A., Christodoulou,A., Christoforou,M., Kamilari,C.,
            Lederer,C.W. and Santama,N.
  TITLE     A novel family of katanin-like 2 protein isoforms (KATNAL2),
            interacting with nucleotide-binding proteins Nubp1 and Nubp2, are
            key regulators of different MT-based processes in mammalian cells
  JOURNAL   Cell Mol Life Sci 73 (1), 163-184 (2016)
   PUBMED   26153462
  REMARK    GeneRIF: KATNAL2 isoforms interact with themselves, with each other
            and with Nubp1 and Nubp2.
REFERENCE   3  (bases 1 to 2139)
  AUTHORS   Kypri,E., Christodoulou,A., Maimaris,G., Lethan,M., Markaki,M.,
            Lysandrou,C., Lederer,C.W., Tavernarakis,N., Geimer,S.,
            Pedersen,L.B. and Santama,N.
  TITLE     The nucleotide-binding proteins Nubp1 and Nubp2 are negative
            regulators of ciliogenesis
  JOURNAL   Cell Mol Life Sci 71 (3), 517-538 (2014)
   PUBMED   23807208
  REMARK    GeneRIF: The nucleotide-binding proteins Nubp1 and Nubp2 are
            negative regulators of ciliogenesis.
REFERENCE   4  (bases 1 to 2139)
  AUTHORS   Nakano,Y., Jahan,I., Bonde,G., Sun,X., Hildebrand,M.S.,
            Engelhardt,J.F., Smith,R.J., Cornell,R.A., Fritzsch,B. and Banfi,B.
  TITLE     A mutation in the Srrm4 gene causes alternative splicing defects
            and deafness in the Bronx waltzer mouse
  JOURNAL   PLoS Genet 8 (10), e1002966 (2012)
   PUBMED   23055939
REFERENCE   5  (bases 1 to 2139)
  AUTHORS   Schnatwinkel,C. and Niswander,L.
  TITLE     Nubp1 is required for lung branching morphogenesis and distal
            progenitor cell survival in mice
  JOURNAL   PLoS One 7 (9), e44871 (2012)
   PUBMED   23028652
  REMARK    GeneRIF: Nubp1 represents an essential protein for lung progenitor
            survival by coordinating vital cellular processes including cell
            polarity and centrosomal dynamics
REFERENCE   6  (bases 1 to 2139)
  AUTHORS   Okuno,T., Yamabayashi,H. and Kogure,K.
  TITLE     Comparison of intracellular localization of Nubp1 and Nubp2 using
            GFP fusion proteins
  JOURNAL   Mol Biol Rep 37 (3), 1165-1168 (2010)
   PUBMED   19263241
  REMARK    GeneRIF: The C-terminal domain or motif of Nubp1 plays an important
            role in regulation of localization of Nubp1 protein.
REFERENCE   7  (bases 1 to 2139)
  AUTHORS   Christodoulou,A., Lederer,C.W., Surrey,T., Vernos,I. and Santama,N.
  TITLE     Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is
            implicated in the regulation of centrosome duplication
  JOURNAL   J Cell Sci 119 (Pt 10), 2035-2047 (2006)
   PUBMED   16638812
  REMARK    GeneRIF: KIFC5A interacts with nucleotide-binding proteins 1 and 2
            (Nubp1 and Nubp2). Nubp1 and Nubp2 also interact with each other.
REFERENCE   8  (bases 1 to 2139)
  AUTHORS   Nakashima,H., Grahovac,M.J., Mazzarella,R., Fujiwara,H.,
            Kitchen,J.R., Threat,T.A. and Ko,M.S.
  TITLE     Two novel mouse genes--Nubp2, mapped to the t-complex on chromosome
            17, and Nubp1, mapped to chromosome 16--establish a new gene family
            of nucleotide-binding proteins in eukaryotes
  JOURNAL   Genomics 60 (2), 152-160 (1999)
   PUBMED   10486206
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ183745.1, CX210766.1, BU614991.1, BM938167.1 and BI134234.1.
            
            On Aug 12, 2009 this sequence version replaced NM_011955.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031430.1, BC055436.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-408               CJ183745.1         1-408
            409-1039            CX210766.1         97-727
            1040-1434           BU614991.1         321-715
            1435-2037           BM938167.1         10-612
            2038-2139           BI134234.1         1-102               c
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 5.61 cM"
     gene            1..2139
                     /gene="Nubp1"
                     /note="nucleotide binding protein 1"
                     /db_xref="GeneID:26425"
                     /db_xref="MGI:MGI:1347073"
     exon            1..58
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1002
                     /gene="Nubp1"
                     /codon_start=1
                     /product="cytosolic Fe-S cluster assembly factor NUBP1"
                     /protein_id="NP_036085.1"
                     /db_xref="CCDS:CCDS27948.1"
                     /db_xref="GeneID:26425"
                     /db_xref="MGI:MGI:1347073"
                     /translation="MEEAPHGCPGADSAQAGRGASCQGCPNQRLCASGAGAAPDPAVE
                     EIREKMKTVRHKLLVLSGKGGVGKSTFSAHLAHGLAEDGDTQVALLDIDICGPSIPKI
                     MGLEGEQVHQSGSGWSPVYVDDNLGVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDV
                     DWGDVDYLIVDTPPGTSDEHLSVVQYLAAAHIDGAVILTTPQEVALQDVRKEISFCHK
                     VKLPIIGVVENMSGFICPKCKKESQIFPPTTGGAEAMCQDLRIPLLGKVPLDPHIGKS
                     CDKGQSFFVEAPDSPATAAYRSIIQRIRDFCNSHQSHAETLISP"
     exon            59..163
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            164..297
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            298..366
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            367..399
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            400..490
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            491..645
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            646..756
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            757..859
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            860..943
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     exon            944..2131
                     /gene="Nubp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1211..1216
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nubp1"
                     /note="hexamer: AATAAA"
     polyA_site      1234
                     /gene="Nubp1"
                     /note="major polyA site"
     regulatory      2102..2107
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nubp1"
                     /note="hexamer: AAGAAA"
     polyA_site      2131
                     /gene="Nubp1"
ORIGIN      
        1 tgaggttccg gcgagcgcag cccgggcaag agcggcagca tggaggaggc gccccacggc
       61 tgccccgggg ccgacagcgc ccaggccggc cgaggagcct cgtgccaggg atgccccaac
      121 cagaggctgt gcgcatccgg agccggcgct gctccggatc ccgccgtgga ggaaatcaga
      181 gagaagatga agacggtgag acacaagctc ttggtgctgt ctgggaaagg cggcgttggg
      241 aaaagcacgt tcagtgcaca cctcgcccac ggcctagcgg aggatggaga tacacaggtt
      301 gctcttctgg acatcgatat ctgtgggcca tcgattccca agatcatggg cttagaagga
      361 gagcaggttc accagagcgg ctccggctgg tctccagtgt acgtggatga caatctgggg
      421 gtgatgtcag tgggcttcct gcttagcagc ccagatgatg ctgtcatctg gaggggacca
      481 aagaaaaatg gtatgatcaa gcagttcctc cgtgatgtag actggggaga cgtggactac
      541 ctcatcgtag acaccccgcc tggcacgtct gacgaacacc tctcagtggt ccagtacctg
      601 gctgcggcac acattgatgg ggcagtgatc ctcaccaccc ctcaggaggt ggccctccag
      661 gatgtccgga aagagatcag cttctgccac aaggtgaagc tgcccatcat tggtgtggta
      721 gaaaacatga gcggtttcat ctgccccaag tgcaagaaag agtctcagat cttccctccc
      781 acgactgggg gtgcagaggc catgtgccag gatctgagga ttccacttct gggcaaagtg
      841 ccgctggatc cacacatagg caagagctgt gacaaaggcc agtctttttt tgtcgaagct
      901 ccagattcac cagccacagc agcctacaga agtataattc agaggatccg agacttttgt
      961 aattctcatc agtcacatgc tgagaccctc atcagtccct gaagtggaac aggaccgagt
     1021 gccacctgct aaccccagag ttggcaggcc acgtgtccag acacctgggc aatgggggac
     1081 aggtggtacc atagccacca gatgctgaca ggatttgaag tcactcatta agacactgta
     1141 atcacctatc tgcctatttc ctcgagatca aaggtacggg cgctctgcat ccaggtgcca
     1201 ttcatcagaa aataaaaatg tctccttgaa cctatccctt agggcctgct tcctggaatc
     1261 caagggacta ggaactctct gagtcacagg actcccagga actgtttctg cctcatgtga
     1321 taagcctagg gagacacaga ggggggatga cactgcctgt gcccacactg gggtctccag
     1381 ctctgggagg tctccagtca tgctgggatc ggtgtgggtg ctttggctgg gggccatcag
     1441 agcccctggc aaagcctgta agtcacccat gaggtgacgg tgccttcaag acatccggta
     1501 ttgcccaggg tcccaggcaa accatcacct ggcacgtctg aggcacagat gtaattgtcc
     1561 tcgtgatccg ggactaagac gtagaactga gagctgctga gggaattcat tccagatttc
     1621 cactgtactg tggtgtgaca ctggaatatg ggcagccccc tcccctatcc tctccttccc
     1681 ctgtacacgt aaactcttgg agtgtactgg ggtccctgta gggcagatgt gacctttcca
     1741 aagctcgatg ggtcccgagc aggccctaaa tatcggggtt ctagcttgga cttgttctgg
     1801 gtcaacttgg aggactggga aaggccacct aggcctggag cacaggtcag gagctgcttt
     1861 cccacaggtg ctcaggcctc tggcctgcac gtgctgctca cctagtgccg gtggatgtcc
     1921 agcccttcca gcctgggctt ctcgaagtca cctgggaagt cctgcaaggc aagagaagcc
     1981 atgactgtcc caacaaagag cagactcact ggggagaccc acagccacaa gtagccaaaa
     2041 agaatcctcc atccctcatt tctgacaact tgacaattgg caattattaa gacaattatc
     2101 caagaaatat ttcctagctt caaaacaaaa aaaaaaaaa
//
