LOCUS       NM_001358870            1802 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus netrin 5 (Ntn5), transcript variant 4, mRNA.
ACCESSION   NM_001358870 XM_006540887
VERSION     NM_001358870.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Dali,O., D'Cruz,S., Legoff,L., Diba Lahmidi,M., Heitz,C.,
            Merret,P.E., Kernanec,P.Y., Pakdel,F. and Smagulova,F.
  TITLE     Transgenerational epigenetic effects imposed by neonicotinoid
            thiacloprid exposure
  JOURNAL   Life Sci Alliance 7 (2), e202302237 (2023)
   PUBMED   37973188
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  AUTHORS   Ikegaya,S., Iga,Y., Mikawa,S., Zhou,L., Abe,M., Sakimura,K.,
            Sato,K. and Yamagishi,S.
  TITLE     Decreased Proliferation in the Neurogenic Niche, Disorganized
            Neuroblast Migration, and Increased Oligodendrogenesis in Adult
            Netrin-5-Deficient Mice
  JOURNAL   Front Neurosci 14, 570974 (2020)
   PUBMED   33324143
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1802)
  AUTHORS   Garrett,A.M., Jucius,T.J., Sigaud,L.P., Tang,F.L., Xiong,W.C.,
            Ackerman,S.L. and Burgess,R.W.
  TITLE     Analysis of Expression Pattern and Genetic Deletion of Netrin5 in
            the Developing Mouse
  JOURNAL   Front Mol Neurosci 9, 3 (2016)
   PUBMED   26858598
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167242.4.
            
            On Jan 4, 2023 this sequence version replaced NM_001358870.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.12532448.1,
                                           SRR14995047.985324.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AC167242.4         85037-85158
            123-767             AC167242.4         86841-87485
            768-956             AC167242.4         91707-91895
            957-1106            AC167242.4         92072-92221
            1107-1160           AC167242.4         92544-92597
            1161-1241           AC167242.4         93001-93081
            1242-1802           AC167242.4         94656-95216
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 29.43 cM"
     gene            1..1802
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /note="netrin 5"
                     /db_xref="GeneID:243967"
                     /db_xref="MGI:MGI:2685330"
     exon            1..122
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..1636
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /note="isoform d precursor is encoded by transcript
                     variant 4; netrin-1-like protein"
                     /codon_start=1
                     /product="netrin-5 isoform d precursor"
                     /protein_id="NP_001345799.1"
                     /db_xref="GeneID:243967"
                     /db_xref="MGI:MGI:2685330"
                     /translation="MTDYRTLFSSPGAGSTVTTPITLSLLLLLSQATSDPCYDPGGRP
                     RFCLPPVTQLVGKAAAPCSQTCALPAASPGPACNSSLTLDLDGSFLLTSVTLRFCTAG
                     PPALVLSAAWATGGPWRPLWRRPAWPGALGGPKKVTFHSPPGPKTRIVASYLRVEFGG
                     KAGLVTTGVRGRCQCHGHAARCATRAQPPRCRCRHHTTGPGCESCRPSHRDWPWRPAT
                     PQHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR
                     DPSQPITSHKACRACQCHPIGATGGMCNQTSGQCSCKLGVTGLTCNRCGPGYQQSRSP
                     RMPCQRIPEATTTPATTPVASRSDPQCQGYCNVSVSSVHMSLQRYCQQDYVLHAQVSA
                     SSSQPSEAVGPEWWRLAVHVLAVFKQRAWPVRRGGQEAWVPRADLICGCLRLRPGADY
                     LLLGRAAQTHDDDNYDPARLILNRHGLALPWRPRWARPLRRLQQKERGGACRGLLPPT
                     RSPGPRN"
     exon            123..767
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     exon            768..956
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1106
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1160
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1241
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1802
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1779..1784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /note="hexamer: AATAAA"
     polyA_site      1802
                     /gene="Ntn5"
                     /gene_synonym="Gm484"
                     /note="major polyA site"
ORIGIN      
        1 agaaccccca ctagcctggg cctgagaaca gccactctca ctcctcccga gagccctcca
       61 agtgcttctc ctacagaaga gtgtggggat gaccgactac aggacactct tttcttctcc
      121 aggtgccggc tctactgtga ccacgcccat taccctcagc ctcttgctcc tccttagcca
      181 ggccacctca gacccatgct atgatccagg agggcgccct cgcttttgcc tcccaccagt
      241 gacccagttg gttggcaagg cagcagcccc ctgctctcag acctgtgctc ttcctgcagc
      301 cagccctggc cctgcctgca acagtagtct gaccctggac ctggacggct ccttcctctt
      361 gacatctgtg accctgcgtt tctgcacagc gggacctcca gccctggttc tttctgctgc
      421 ctgggccact ggggggccct ggaggccact atggcgtagg cctgcctggc ctggggctct
      481 ggggggcccc aagaaggtaa cctttcactc ccccccaggc cccaagacca ggatagtggc
      541 cagctacctc cgtgtggagt tcgggggaaa agcagggctg gtgaccactg gagtaagagg
      601 ccgctgccag tgccacggcc acgctgcccg ctgtgccact cgggcccagc ccccacgctg
      661 ccgctgccgc caccacacca ctggcccagg gtgtgagagc tgtcgcccat cccatcgaga
      721 ctggccctgg cgacctgcca caccccagca ccctcacccg tgcttgccct gttcctgcaa
      781 tcagcatgcc cgccgctgcc gattcaactc cgagctattc aggttgtcag gtggccgtag
      841 tgggggtgtg tgtgagcggt gccgccacca cacagctggg cggcactgtc actactgcca
      901 gccagggttc tggagggacc cgagccagcc catcactagt cacaaggcat gcagggcctg
      961 ccagtgccac ccaattggag caacgggagg gatgtgcaac cagaccagtg gccagtgctc
     1021 ctgcaagtta ggggtcacag gcctgacatg caatcgctgt ggtcctggct accagcagag
     1081 ccgctcaccc aggatgccct gccaacgaat tccagaggca acaactaccc ctgctactac
     1141 ccctgttgca tctcgatcag acccacagtg tcaaggctat tgcaatgtct ccgtcagcag
     1201 tgtgcacatg agccttcaga gatactgtca gcaggattat gttctgcacg cccaggtttc
     1261 agcgtcgtcg tcgcagccgt ctgaggcggt gggccccgag tggtggcggc tggccgtgca
     1321 cgtgctggct gtgttcaaac agcgtgcgtg gcccgtgcgc cgcggtggcc aggaggcctg
     1381 ggtgccacgt gctgacctaa tctgcggctg cctgcgcctg cgccctggcg ctgactacct
     1441 cctgctgggc cgtgctgcgc agacccacga cgacgacaac tatgaccctg cgcgcctcat
     1501 cctgaaccgc cacggcctcg cgctgccctg gagaccacga tgggcccggc cgctgcggcg
     1561 actgcagcag aaggagcgcg gaggtgcctg ccgaggcctg ctgccaccca cacggagccc
     1621 tgggcccagg aactaaagtg agctactaat gtaaggtgtg agtccccaga gccaatcaga
     1681 agcttcagtg cccgtgacgc cactccgcat gtgacgttgc ctacgttggg accggaagtg
     1741 actgcttgga cctgtgagcc ttataggtta tttgtcacaa taaaggctca tgtcttgtgg
     1801 aa
//
