LOCUS       NM_029734               1409 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus N-terminal glutamine amidase 1 (Ntaq1), transcript
            variant 1, mRNA.
ACCESSION   NM_029734 XM_128102
VERSION     NM_029734.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1409)
  AUTHORS   Kole,C., Berdugo,N., Da Silva,C., Ait-Ali,N., Millet-Puel,G.,
            Pagan,D., Blond,F., Poidevin,L., Ripp,R., Fontaine,V., Wincker,P.,
            Zack,D.J., Sahel,J.A., Poch,O. and Leveillard,T.
  TITLE     Identification of an Alternative Splicing Product of the Otx2 Gene
            Expressed in the Neural Retina and Retinal Pigmented Epithelial
            Cells
  JOURNAL   PLoS One 11 (3), e0150758 (2016)
   PUBMED   26985665
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1409)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   4  (bases 1 to 1409)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1409)
  AUTHORS   Piatkov,K.I., Colnaghi,L., Bekes,M., Varshavsky,A. and Huang,T.T.
  TITLE     The auto-generated fragment of the Usp1 deubiquitylase is a
            physiological substrate of the N-end rule pathway
  JOURNAL   Mol Cell 48 (6), 926-933 (2012)
   PUBMED   23159736
REFERENCE   6  (bases 1 to 1409)
  AUTHORS   Wang,H., Piatkov,K.I., Brower,C.S. and Varshavsky,A.
  TITLE     Glutamine-specific N-terminal amidase, a component of the N-end
            rule pathway
  JOURNAL   Mol Cell 34 (6), 686-695 (2009)
   PUBMED   19560421
  REMARK    GeneRIF: Site-directed mutagenesis of Ntaq1 and its crystal
            structure indicate that the active site and catalytic mechanism of
            Nt(Q)-amidase are similar to those of transglutaminases.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FO710768.1, AK150578.1 and AI843652.1.
            
            On May 21, 2016 this sequence version replaced NM_029734.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC051524.1, AK150578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                FO710768.1         1-11
            12-1392             AK150578.1         2-1382
            1393-1409           AI843652.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 24.38 cM"
     gene            1..1409
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /note="N-terminal glutamine amidase 1"
                     /db_xref="GeneID:76773"
                     /db_xref="MGI:MGI:1924023"
     exon            1..216
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     exon            217..316
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     exon            317..367
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     exon            368..516
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     exon            517..641
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     exon            642..1394
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1373..1378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /note="hexamer: AATAAA"
     polyA_site      1394
                     /gene="Ntaq1"
                     /gene_synonym="2410187C16Rik; Wdyhv1"
                     /note="major polyA site"
ORIGIN      
        1 cggctctcgg ctctcccacc cggaaactgt cctggccgcc tactctgttg tcctctcctc
       61 ctgggagact ggcgacaatt gcggccagcg ggttgtttag ttgacctgtg agccacagct
      121 tcgggtcatg gagggggacg gccccgccgc cacggccccg cagtaccagc cggtctgtcc
      181 tacgcgggac gcatgtgtct acaacagctg ctattgtgag gaaaacattt ggaagctctg
      241 tgagtacatc aagacacaca accagtatct gttggaggag tgctatgcag tcttcatatc
      301 aaatgagaag aagatggtac ctatttggaa acagcaggca agacctgaga atggacctgt
      361 gatctgggac taccatgtgg ttctgcttca tgtgtcaagg gaaggacaaa gcttcattta
      421 tgatcttgac actattttgc catttccctg ccctttcgac atttacatag aagatgccct
      481 taagtctgat gatgacattc atctgcagtt taggaggaaa tttagagtgg ttcgtgctga
      541 ctcctacttg aagcacttcg cttctgaccg gtctcacatg aaagactcca gtgggaactg
      601 gagagagcct cccccagagt acccctgcat tgaaactgga gactccaaaa tgaacctgaa
      661 cgacttcatc agcatggacc ctgcagtagg atggggagct gtctacacgc tgcctgagtt
      721 tgtgcatcgg ttcagcagca aaacctacca agcctgacat ccgggctgca gctagagaag
      781 ctctagggtc tgagtaagcc atccttccat ttaagagaga gcgtggtaca ggtggcctat
      841 agggatattg ttctcactaa atgtgagtgg aaacattagt gaacacagat gaaaatgaat
      901 gactaagtcc cccaccccct ttttttaggc tggggatcta tcccagagtt ctatctccaa
      961 ccctaaacag tcagacccca gcctcagaca tagatatgcc acattcggta tatggttgct
     1021 aaaatgtttc catggcttgc ttacttcggt gtgtgatgac gtaggccagc aattgctttt
     1081 gtaaaactag aggtgtggac ctggagtcgg ctccttttgt ctgcttcctc tgcttcctgt
     1141 ctggctagac tctaaactcc ttgagcacag gtttgtggcc tgtggctcta agactctgtt
     1201 gcccattaga ggtcccggta aaatgtttct agagtcagca ctgctgcttg gtaagggaca
     1261 gtattgtgag ctgaatcagc tgtaagtatt agtctttttg gactacgatg tttaaaaaag
     1321 ttgcagatat cttgtctgag tgctatttga cccacttata tatgtagttt taaataaaat
     1381 tgacttaaaa ttaaaaaaaa aaaaaaaaa
//
