LOCUS       NM_025751               2157 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus 5' nucleotidase, ecto-like (Nt5el), mRNA.
ACCESSION   NM_025751
VERSION     NM_025751.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2157)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2157)
  AUTHORS   Adissu,H.A., Estabel,J., Sunter,D., Tuck,E., Hooks,Y.,
            Carragher,D.M., Clarke,K., Karp,N.A., Newbigging,S., Jones,N.,
            Morikawa,L., White,J.K. and McKerlie,C.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Histopathology reveals correlative and unique phenotypes in a
            high-throughput mouse phenotyping screen
  JOURNAL   Dis Model Mech 7 (5), 515-524 (2014)
   PUBMED   24652767
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            AC154281.2.
            
            On Apr 29, 2007 this sequence version replaced NM_025751.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK016919.1, AK016761.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AC154281.2         47542-47770         c
            230-381             AC154281.2         29307-29458         c
            382-962             AC154281.2         20036-20616         c
            963-1110            AC154281.2         18647-18794         c
            1111-1276           AC154281.2         17375-17540         c
            1277-1424           AC154281.2         11094-11241         c
            1425-1611           AC154281.2         9895-10081          c
            1612-2157           AC154281.2         8110-8655           c
FEATURES             Location/Qualifiers
     source          1..2157
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 56.92 cM"
     gene            1..2157
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /note="5' nucleotidase, ecto-like"
                     /db_xref="GeneID:66763"
                     /db_xref="MGI:MGI:1914013"
     exon            1..229
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1796
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /codon_start=1
                     /product="uncharacterized protein LOC66763"
                     /protein_id="NP_080027.1"
                     /db_xref="CCDS:CCDS26755.1"
                     /db_xref="GeneID:66763"
                     /db_xref="MGI:MGI:1914013"
                     /translation="MEAPEEEPPALAPPQPAKLGEELSPQTQGNQSGDMDSYNLTILH
                     FNDVYDVDSSTEEPVGGAARFATAVKRFSILNPLLIFSGDCLNPSILSTITKGKHMIS
                     ILNELGVHFAVFGNHEFDFGVDILEEYMKQMHFTWFLSNVHDRFTSEPLGHGAVKKIV
                     NWNNRKIGLMGLVEEDWLDTLATVNKANVNYKDYVETANELAVELRAEGADLVIAMTH
                     MKWKNDTRLAQHAEGLDLILGGHDHEYGIKKVNETWIVKSGSDFKNLTKIDIQLFDAS
                     FQYVFEKVEILSYLEEDSYIKAIVRDFTQNIQYMLEEVLCPIDVALDGREITVRRCES
                     NLGNLVTNAMLEATHADVALLNSGTLRYDRIHPPGNFTLHDLLAILPIVDPVLVVRAT
                     GAQLLEALENGVYKYPALDGRFPQVAGLEFGFDPDAEPGHRVIRDTVKVQGQYLQRKK
                     VYLLAIKEYIANGKDGYSMFRACPRMFDPETAQVLSTVVMNHFESIKILQGKKKCLSG
                     HRMSLITTTNKSPSLTAFEEETDGPLGVIAVPGLEGRIFHISPDMKEHLHQLRAARQQ
                     GLRTFPTISDSARETSDSD"
     exon            230..381
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            382..962
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1110
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1276
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1424
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1611
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..2157
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2045..2050
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /note="hexamer: AATGAA"
     polyA_site      2061
                     /gene="Nt5el"
                     /gene_synonym="4933425L06Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaggttctga gagaggcgtc ctagactgta cctgagaaat ggaggcccct gaggaagagc
       61 cacctgctct ggcaccccct cagcctgcga agcttgggga agaactctct ccccaaaccc
      121 aggggaacca gtcaggagac atggactcct ataacttgac tatacttcat ttcaacgatg
      181 tttacgatgt ggactcgagt actgaagagc ctgtaggagg cgctgctagg tttgccacag
      241 ccgtgaaaag attcagcatc ctgaatccac tcttgatttt cagtggcgac tgcttaaatc
      301 cttccatctt aagcacaata acaaaaggaa agcatatgat ctctatatta aatgagttgg
      361 gagtacattt tgcagttttt ggaaaccatg agtttgattt tggtgttgat attttggaag
      421 agtatatgaa acaaatgcac tttacctggt tcctcagtaa cgtccatgac agattcacat
      481 ctgaacctct tgggcatggt gcagtcaaaa agatagttaa ctggaacaat cggaaaattg
      541 gcttaatggg actagttgaa gaagactggc ttgatactct ggccacagtt aataaggcca
      601 atgtaaatta taaagattat gtggaaactg ctaatgagct agccgtggag ctccgagcag
      661 aaggggctga ccttgtgatc gccatgacgc acatgaagtg gaaaaatgac accaggcttg
      721 cccagcatgc agaagggctt gatttgatcc tgggaggcca tgaccacgaa tatgggatca
      781 agaaagtgaa cgagacttgg attgtcaaga gtggatctga ttttaaaaat ctgacaaaaa
      841 tagacataca gctgttcgat gcttcgttcc agtatgtatt tgagaaagtg gaaattttga
      901 gctacttgga agaagattca tatatcaaag caatagtaag agattttact caaaacatac
      961 agtatatgtt agaagaagtt ctttgcccaa ttgatgtggc attggatggc cgtgagatta
     1021 ctgtaagaag atgtgagagc aaccttggaa atctggtgac aaatgcaatg ttagaggcca
     1081 cgcatgctga tgtggcactc cttaattcag gtactctcag gtatgacaga atacacccgc
     1141 cagggaattt cactctgcat gaccttttgg ccatactccc cattgtggac ccagttttag
     1201 ttgtcagagc aacgggtgca cagctgctgg aagcacttga aaatggggtt tacaagtacc
     1261 cagctctgga tggcaggttt cctcaagttg ctgggttaga atttggattt gatccagatg
     1321 cagaaccagg ccatcgagtc ataagagaca ctgtgaaagt tcaaggacag tacttacaga
     1381 ggaagaaagt ctatctgctg gccatcaagg agtacattgc aaacgggaag gatggctaca
     1441 gtatgtttag agcttgccct cggatgtttg accccgagac agctcaggtg ctgtctacag
     1501 tcgtcatgaa tcactttgaa tccataaaaa ttttgcaagg aaagaagaag tgtctttccg
     1561 gccatcggat gagtttgatc acgacgacaa acaaatcgcc atccctcaca gcctttgagg
     1621 aagaaacaga tgggccattg ggagtaattg cagtgcctgg cctagaagga agaatcttcc
     1681 atatttctcc agacatgaaa gaacatttgc accaacttag agctgcgaga cagcaaggcc
     1741 tgagaacttt ccccaccatt agtgacagtg cacgtgagac ctctgattct gactaactgt
     1801 aatggagttg gtatgttttg ttagtgctca aatggatcgg accaagttta gcagtgttag
     1861 acatggtaac agaatcttga ttgcatgtat cattctagaa ttgatgataa ttctagggat
     1921 attgctctaa atgttctttt catttaaatt ttatcaagtc ttgtaacttt tgactcttca
     1981 ttgtgttggg ccagaaacac aaacatttgt gattaaagtg taaacagtat agtgtttatt
     2041 attaaatgaa attcatgctc acctcttcac agtacttatt tgtatagtaa ccttttttct
     2101 cttagtattg cttatttttc tgttcaaatg agtgaataaa tacatatata tcctctc
//
