LOCUS       NM_153529               1622 bp    mRNA    linear   ROD 04-OCT-2024
DEFINITION  Mus musculus neuritin 1 (Nrn1), transcript variant 1, mRNA.
ACCESSION   NM_153529
VERSION     NM_153529.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Cai,C., Luo,Q., Jia,L., Xia,Y., Lan,X., Wei,X., Shi,S., Liu,Y.,
            Wang,Y., Xiong,Z., Shi,R., Huang,C. and Chen,Z.
  TITLE     TRIM67 Implicates in Regulating the Homeostasis and Synaptic
            Development of Mitral Cells in the Olfactory Bulb
  JOURNAL   Int J Mol Sci 24 (17), 13439 (2023)
   PUBMED   37686246
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  AUTHORS   Boudkkazi,S., Schwenk,J., Nakaya,N., Brechet,A., Kollewe,A.,
            Harada,H., Bildl,W., Kulik,A., Dong,L., Sultana,A., Zolles,G.,
            Schulte,U., Tomarev,S. and Fakler,B.
  TITLE     A Noelin-organized extracellular network of proteins required for
            constitutive and context-dependent anchoring of AMPA-receptors
  JOURNAL   Neuron 111 (16), 2544-2556 (2023)
   PUBMED   37591201
REFERENCE   3  (bases 1 to 1622)
  AUTHORS   Jiang,Y., Li,J.J., Mu,Y.W., Jiang,H.Y., Wei,Z.X., Xiao,Z.Y.,
            Zhao,J.J. and Chen,X.H.
  TITLE     Overexpression of Cpg15 Alleviates the Oxidative Stress in Neuronal
            Cells Via Regulating Redox Enzymes and Nrf2 Antioxidative Pathway
  JOURNAL   Neurotox Res 40 (2), 365-372 (2022)
   PUBMED   35038134
  REMARK    GeneRIF: Overexpression of Cpg15 Alleviates the Oxidative Stress in
            Neuronal Cells Via Regulating Redox Enzymes and Nrf2 Antioxidative
            Pathway.
REFERENCE   4  (bases 1 to 1622)
  AUTHORS   Sato,H., Hatakeyama,J., Iwasato,T., Araki,K., Yamamoto,N. and
            Shimamura,K.
  TITLE     Thalamocortical axons control the cytoarchitecture of neocortical
            layers by area-specific supply of VGF
  JOURNAL   Elife 11, e67549 (2022)
   PUBMED   35289744
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1622)
  AUTHORS   Turrero Garcia,M., Stegmann,S.K., Lacey,T.E., Reid,C.M.,
            Hrvatin,S., Weinreb,C., Adam,M.A., Nagy,M.A. and Harwell,C.C.
  TITLE     Transcriptional profiling of sequentially generated septal neuron
            fates
  JOURNAL   Elife 10, e71545 (2021)
   PUBMED   34851821
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1622)
  AUTHORS   Harwell,C., Burbach,B., Svoboda,K. and Nedivi,E.
  TITLE     Regulation of cpg15 expression during single whisker experience in
            the barrel cortex of adult mice
  JOURNAL   J Neurobiol 65 (1), 85-96 (2005)
   PUBMED   16010668
  REMARK    GeneRIF: Regulation of cpg15 expression during single whisker
            experience in the barrel cortex of adult mice.
REFERENCE   7  (bases 1 to 1622)
  AUTHORS   Kojima,N., Shiojiri,N., Sakai,Y. and Miyajima,A.
  TITLE     Expression of neuritin during liver maturation and regeneration
  JOURNAL   FEBS Lett 579 (21), 4562-4566 (2005)
   PUBMED   16081067
  REMARK    GeneRIF: Data show that neuritin expression is well correlated to
            the maturation of hepatocytes and can be a useful tool to define
            the differentiation stage of hepatocytes.
REFERENCE   8  (bases 1 to 1622)
  AUTHORS   Fujino,T., Lee,W.C. and Nedivi,E.
  TITLE     Regulation of cpg15 by signaling pathways that mediate synaptic
            plasticity
  JOURNAL   Mol Cell Neurosci 24 (3), 538-554 (2003)
   PUBMED   14664806
  REMARK    GeneRIF: Cpg15 is an immediate-early gene induced by Ca(2+) influx
            through NMDA receptors and L-type voltage-sensitive calcium
            channels. It requires convergent activation of the CaM kinase and
            MAP kinase pathways.
REFERENCE   9  (bases 1 to 1622)
  AUTHORS   Erkman,L., Yates,P.A., McLaughlin,T., McEvilly,R.J., Whisenhunt,T.,
            O'Connell,S.M., Krones,A.I., Kirby,M.A., Rapaport,D.H.,
            Bermingham,J.R., O'Leary,D.D. and Rosenfeld,M.G.
  TITLE     A POU domain transcription factor-dependent program regulates axon
            pathfinding in the vertebrate visual system
  JOURNAL   Neuron 28 (3), 779-792 (2000)
   PUBMED   11163266
REFERENCE   10 (bases 1 to 1622)
  AUTHORS   Naeve,G.S., Ramakrishnan,M., Kramer,R., Hevroni,D., Citri,Y. and
            Theill,L.E.
  TITLE     Neuritin: a gene induced by neural activity and neurotrophins that
            promotes neuritogenesis
  JOURNAL   Proc Natl Acad Sci U S A 94 (6), 2648-2653 (1997)
   PUBMED   9122250
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156802.7, AK161859.1, CA321643.1, CD774577.1 and BY643925.1.
            
            On Mar 9, 2013 this sequence version replaced NM_153529.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC035531.1, AK003046.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AC156802.7         57751-57783
            34-641              AK161859.1         2-609
            642-1350            CA321643.1         35-743
            1351-1619           CD774577.1         16-284              c
            1620-1622           BY643925.1         374-376
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 14.44 cM"
     gene            1..1622
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /note="neuritin 1"
                     /db_xref="GeneID:68404"
                     /db_xref="MGI:MGI:1915654"
     exon            1..242
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /inference="alignment:Splign:2.1.0"
     exon            243..387
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /inference="alignment:Splign:2.1.0"
     exon            388..1622
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1599..1604
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /note="hexamer: AATAAA"
     polyA_site      1619
                     /gene="Nrn1"
                     /gene_synonym="0710008J23Rik; Cpg15; Nrn"
                     /note="major polyA site"
ORIGIN      
        1 actctctcac tctctttctg tctcttcctc gctccctctc tttctctcct ccctctgcct
       61 tcccagtgca taaagtctct gtcgctcccg gaacttgttg gcaatgccta tttttcagct
      121 ttcccccgcg ttctctaaac taactattta aaggtctgcg gtcgcaaatg gtttgactaa
      181 acgtaggatg ggacttaagt tgaacggcag atatatttca ctgatcctcg cggtgcaaat
      241 agcttacctg gtgcaggccg tgagagcagc gggcaagtgt gatgcagtct ttaagggctt
      301 ttcagactgt ttgctcaagc tgggcgacag catggccaac tacccgcagg gcctggacga
      361 caagacgaac atcaagaccg tgtgcacata ctgggaggat ttccacagct gcacggtcac
      421 agctcttacg gattgccagg aaggggcgaa agatatgtgg gataaactga gaaaagaatc
      481 gaaaaacctc aacatccaag gcagcttatt cgaactctgc ggcagcagca acggggcggc
      541 ggggtccctg ctcccggcgc tttccgtgct cctggtgtct ctctcggcag ctttagcgac
      601 ctggttttcc ttctgagcgc gggaccgggt ccccccctcc ccctccgctc actcacccac
      661 actcacacca tgctcccgga aatcgagagg aatagccatt cgttctctga ggacgttgtg
      721 attctctgtg atgttgaaaa cactcatatg ggattgtggg aaatcctgtt tctctctttt
      781 tcttcttctt ttttttttct tctttttaat tgtgtttgat tccttgtgtt ttatttgcca
      841 aatgttaccg atcagtgagc gagcgagcac agccaaaatc ggacctcacc ttttagtccg
      901 tcttcacaga aaaataagaa aacggcaaac tcacccccat ttttaaattt ttattttatt
      961 ttattttatt ttggcaaaag aatctcagga atggccctgg gccacctact atattaatca
     1021 tgttgataac atgaagaatg atgggctcct cctaatggga aagcgagagg gaaaaggaga
     1081 aggccagggg aatgacttca agagtggtgt ccacgtggga atcagccggt gaataatcat
     1141 gctcacgtct ttcttccaca gtaccttgtt ttgatcattt ccactgcaca tttctcctcc
     1201 agaaaagcga aaacacaaga gtgtgggctt agcatttttt taaggataag acagagagag
     1261 agaaagaggt tgggtatagt gggataggtt gtcataagag atgctgctat ggtcatgagg
     1321 ggccggtttc acctgctatt gtcgatgccc ctcgttcagg tccactgcct ttattttcct
     1381 tcctctcttg ttttagctgt tacacataca gtaatacctg aatatccaac ggtatagatc
     1441 acaagggggt aatcaatgtt aaatctaaaa tagaatttaa aaaaaaagat tttgacataa
     1501 aagagccttg attttaaaaa aagagagaga tgtaatttaa aaagtttatt ataaattaaa
     1561 ttcagcaaaa atttgctaca aagtatagag aagtataaaa taaaagttat tgtttgaaat
     1621 gg
//
