LOCUS       NM_134122               1502 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus nurim (nuclear envelope membrane protein) (Nrm), mRNA.
ACCESSION   NM_134122
VERSION     NM_134122.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1502)
  AUTHORS   Zhang,W., Bai,T., Zhang,S., Xu,S., Chen,H. and Li,C.
  TITLE     Isoforms of the nuclear envelope protein Nurim are differentially
            expressed during heart development in mice
  JOURNAL   Gene 627, 123-128 (2017)
   PUBMED   28600179
  REMARK    GeneRIF: Study describes Nurim isoform expression during
            development and correlate these expression patterns with
            developmental timing and spatial patterns. The reasons for
            increased expression of the Nurim isoforms were not clear; however,
            results suggest that increased expression may be involved in
            cardiac development.
REFERENCE   2  (bases 1 to 1502)
  AUTHORS   Nili,E., Cojocaru,G.S., Kalma,Y., Ginsberg,D., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A., Berger,R., Shaklai,S., Amariglio,N.,
            Brok-Simoni,F., Simon,A.J. and Rechavi,G.
  TITLE     Nuclear membrane protein LAP2beta mediates transcriptional
            repression alone and together with its binding partner GCL
            (germ-cell-less)
  JOURNAL   J Cell Sci 114 (Pt 18), 3297-3307 (2001)
   PUBMED   11591818
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC021750.1.
            
            On Apr 6, 2007 this sequence version replaced NM_134122.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC021750.1, BI851347.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1502              BC021750.1         4-1505
FEATURES             Location/Qualifiers
     source          1..1502
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.72 cM"
     gene            1..1502
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /note="nurim (nuclear envelope membrane protein)"
                     /db_xref="GeneID:106582"
                     /db_xref="MGI:MGI:2146855"
     exon            1..200
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..856
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /note="nuclear rim protein; nuclear envelope membrane
                     protein"
                     /codon_start=1
                     /product="nurim"
                     /protein_id="NP_598883.1"
                     /db_xref="CCDS:CCDS28708.1"
                     /db_xref="GeneID:106582"
                     /db_xref="MGI:MGI:2146855"
                     /translation="MAPALLLVPAALASFILAFGTGVEFVRFTSLRPLLGGIPESGGP
                     DARHGWLAALQDRSILASLAWDLCLLLLFVVQHSLMATEAVKAWTSRYFGVLQRSLYV
                     ACTALALQLVMRYWETTPRGPVLWEARAEPWATWVPLLCFVLHVVSWLLIFSILLVFD
                     YAELMGLKQVYYHVLGLGEPLSLKSPRALRLFSHLRHPVCVELLTVLWVVPTLGTDRL
                     LLALLFTLYLGLAHGLDQQDLRYLRSQLQRKLHLLSRPQDGEAE"
     exon            201..397
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            398..574
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            575..1464
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1444..1449
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1464
                     /gene="Nrm"
                     /gene_synonym="2610307M02Rik"
                     /note="major polyA site"
ORIGIN      
        1 cctgggcagg gccagcagtc gcgggaaccc tgagcccgcc ttctcctcag gctccgcgct
       61 gctcgccatg gcaccggcgc tgctgctggt tcctgcggcc ctcgcctcct tcatcctggc
      121 ctttggcacc ggagtggaat tcgtgcgttt cacctccctg aggccgctgc ttggagggat
      181 cccggagtct ggcggtcccg atgcccgcca cgggtggttg gctgccctgc aggaccggag
      241 cattcttgcc tccttggctt gggatctatg tctgctgcta ctgtttgtgg tacagcacag
      301 ccttatggcg actgaggcag tgaaggcgtg gacatcccgg tactttggcg tccttcagag
      361 gtcgctctat gtggcgtgca cagccctggc cttgcagttg gtgatgcggt actgggagac
      421 tacacccaga ggcccagtgt tatgggaggc tcgggctgaa ccatgggcca cctgggtacc
      481 tctcctctgc tttgtgctcc acgttgtttc ctggctcctc atctttagca tccttctggt
      541 ctttgactac gctgaactga tgggcctcaa gcaggtttat taccatgtgc tgggactggg
      601 cgagcccctg tccctgaagt ctcctcgggc tctgagactc ttttcccacc ttcgacaccc
      661 agtgtgtgtg gagctgctga ctgtgctgtg ggtggtcccc accttgggca ccgatcggct
      721 cctcctggct cttctcttta ccctctacct gggcttggct catgggcttg accagcaaga
      781 tctccgctac cttcggtctc agctacaaag aaaactccac cttctctcca gacctcagga
      841 tggggaagca gagtgaggag ctagttctaa gccctgaatt tacttcccac ctcaaaatca
      901 aatcccttag tatccagacg gagtttgctt cagaccgcgg aggaggttgg aagtcatgcc
      961 ctgaaggggc tgtgccctct cctgctggag aactcagttc ctgaatcttg atcctgaatt
     1021 cttattcaaa gtttcctcca ctggtcttca agatccgcct ctcaccagcc aagaatggtt
     1081 acaaaactca tgagtctcct tttctcttag agcatgacct ccacacacac tgggtcagtt
     1141 cacacagggg agcacctcag ctcacactgg ggagcactca ctcccctggc actgttattg
     1201 gctctgcacc tcagggattc ccttccatgt ttccacctca gggagctatg tcagggccta
     1261 tctgaaagtt tataagtagt ggctcttttg taccgcggct gtgcttcctc cccactcctg
     1321 ccttagtttc tccttaggtc tttccctaca gctctgtgtg gtctcctaag gcgacgtctc
     1381 ccgattttaa ctcgggttga ctcagggctc cctgctctcc caaaggatat gcgctgcaga
     1441 aaaaataaaa ttttatacat atgaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1501 aa
//
