LOCUS       NM_010151               2285 bp    mRNA    linear   ROD 24-OCT-2024
DEFINITION  Mus musculus nuclear receptor subfamily 2, group F, member 1
            (Nr2f1), transcript variant 1, mRNA.
ACCESSION   NM_010151 XM_980546 XM_980577 XM_980610 XM_980647 XM_993943
VERSION     NM_010151.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Greig,L.C., Woodworth,M.B., Poulopoulos,A., Lim,S. and Macklis,J.D.
  TITLE     BEAM: A combinatorial recombinase toolbox for binary gene
            expression and mosaic genetic analysis
  JOURNAL   Cell Rep 43 (8), 114650 (2024)
   PUBMED   39159043
REFERENCE   2  (bases 1 to 2285)
  AUTHORS   Sun,M., Gao,Y., Li,Z., Yang,L., Liu,G., Xu,Z., Guo,R., You,Y. and
            Yang,Z.
  TITLE     ERK signaling expands mammalian cortical radial glial cells and
            extends the neurogenic period
  JOURNAL   Proc Natl Acad Sci U S A 121 (13), e2314802121 (2024)
   PUBMED   38498715
REFERENCE   3  (bases 1 to 2285)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 2285)
  AUTHORS   Alderman,P.J., Saxon,D., Torrijos-Saiz,L.I., Sharief,M., Page,C.E.,
            Baroudi,J.K., Biagiotti,S.W., Butyrkin,V.A., Melamed,A., Kuo,C.T.,
            Vicini,S., Garcia-Verdugo,J.M., Herranz-Perez,V., Corbin,J.G. and
            Sorrells,S.F.
  TITLE     Delayed maturation and migration of excitatory neurons in the
            juvenile mouse paralaminar amygdala
  JOURNAL   Neuron 112 (4), 574-592 (2024)
   PUBMED   38086370
REFERENCE   5  (bases 1 to 2285)
  AUTHORS   Zheng,Y., Zhao,C., Song,Q., Xu,L., Zhang,B., Hu,G., Kong,X., Li,S.,
            Li,X., Shen,Y., Zhuang,L., Wu,M., Liu,Y. and Zhou,Y.
  TITLE     Histone methylation mediated by NSD1 is required for the
            establishment and maintenance of neuronal identities
  JOURNAL   Cell Rep 42 (12), 113496 (2023)
   PUBMED   37995181
REFERENCE   6  (bases 1 to 2285)
  AUTHORS   Pereira,F.A., Qiu,Y., Tsai,M.J. and Tsai,S.Y.
  TITLE     Chicken ovalbumin upstream promoter transcription factor (COUP-TF):
            expression during mouse embryogenesis
  JOURNAL   J Steroid Biochem Mol Biol 53 (1-6), 503-508 (1995)
   PUBMED   7626501
  REMARK    Review article
REFERENCE   7  (bases 1 to 2285)
  AUTHORS   Lopes da Silva,S., Cox,J.J., Jonk,L.J., Kruijer,W. and Burbach,J.P.
  TITLE     Localization of transcripts of the related nuclear orphan receptors
            COUP-TF I and ARP-1 in the adult mouse brain
  JOURNAL   Brain Res Mol Brain Res 30 (1), 131-136 (1995)
   PUBMED   7609634
REFERENCE   8  (bases 1 to 2285)
  AUTHORS   Ben-Shushan,E., Sharir,H., Pikarsky,E. and Bergman,Y.
  TITLE     A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and
            retinoic acid receptor:retinoid X receptor heterodimers regulates
            Oct-3/4 expression in embryonal carcinoma cells
  JOURNAL   Mol Cell Biol 15 (2), 1034-1048 (1995)
   PUBMED   7823919
REFERENCE   9  (bases 1 to 2285)
  AUTHORS   Lu,X.P., Salbert,G. and Pfahl,M.
  TITLE     An evolutionary conserved COUP-TF binding element in a
            neural-specific gene and COUP-TF expression patterns support a
            major role for COUP-TF in neural development
  JOURNAL   Mol Endocrinol 8 (12), 1774-1788 (1994)
   PUBMED   7708064
REFERENCE   10 (bases 1 to 2285)
  AUTHORS   Jonk,L.J., de Jonge,M.E., Pals,C.E., Wissink,S., Vervaart,J.M.,
            Schoorlemmer,J. and Kruijer,W.
  TITLE     Cloning and expression during development of three murine members
            of the COUP family of nuclear orphan receptors
  JOURNAL   Mech Dev 47 (1), 81-97 (1994)
   PUBMED   7947324
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025642.13.
            
            On Apr 4, 2022 this sequence version replaced NM_010151.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X74134.1, BC108408.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-716               CT025642.13        125641-126356       c
            717-1244            CT025642.13        122683-123210       c
            1245-2285           CT025642.13        116494-117534       c
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 41.38 cM"
     gene            1..2285
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /note="nuclear receptor subfamily 2, group F, member 1"
                     /db_xref="GeneID:13865"
                     /db_xref="MGI:MGI:1352451"
     exon            1..716
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /inference="alignment:Splign:2.1.0"
     CDS             263..1525
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /note="isoform a is encoded by transcript variant 1; COUP
                     transcription factor 1; V-erbA-related protein 3; COUP
                     transcription factor I; avian erythroblastic leukemia
                     viral (v-erb-a) oncogene homolog-like 3"
                     /codon_start=1
                     /product="COUP transcription factor 1 isoform a"
                     /protein_id="NP_034281.2"
                     /db_xref="CCDS:CCDS26658.1"
                     /db_xref="GeneID:13865"
                     /db_xref="MGI:MGI:1352451"
                     /translation="MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGEQQQAGSG
                     APHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEG
                     CKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPP
                     TQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICE
                     LAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAA
                     AGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSD
                     AAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVG
                     KTPIETLIRDMLLSGSSFNWPYMSIQCS"
     exon            717..1244
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..2285
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2266..2271
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /note="hexamer: AATAAA"
     polyA_site      2285
                     /gene="Nr2f1"
                     /gene_synonym="COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3;
                     Erbal3; SVP44; Tcfcoup1"
                     /note="major polyA site"
ORIGIN      
        1 acaacaaaac gccagcaggg cgggcgggcg cgcagcagca gcggggcggc tgaggcagta
       61 acggcggcgg cggcggcggc ggcgcaggca gaggccggtg cccggctcgg gctcggctcc
      121 ggcgaccccg gggcgcccgg tgggcccccc gccccctccc cctcccccct tccccttccc
      181 cttcccctcc cagcgcgccc gcgcgccccg cggccctcgg cgagcagctc ggctcccccc
      241 agcgctccct gggcccaaag atatggcaat ggtagttagc agctggcgag atccgcagga
      301 cgacgtggcc gggggcaacc ccggcggccc caaccccgca gcgcaggcag cccgcggcgg
      361 cggcggcggc gagcagcagc aggcgggctc cggcgcgccg cacacgccgc agaccccggg
      421 ccagcccgga gcgcccgcca cccccggcac ggcaggggac aagggccagg gcccgcccgg
      481 ttcaggccag agccagcagc acatcgagtg cgtggtgtgc ggggacaagt cgagcggcaa
      541 gcactacggc caattcacct gcgagggctg caaaagtttc ttcaagagga gcgtccgcag
      601 gaacttaact tacacatgcc gtgccaacag gaactgtccc atcgaccagc accaccgcaa
      661 ccagtgccaa tactgccgcc tcaagaagtg cctcaaagtg ggcatgaggc gggaagcggt
      721 tcagcgagga agaatgcctc caacccagcc caatccaggc cagtatgcac tcacaaacgg
      781 ggatcctctc aatggccact gctacctgtc tggctacatt tctctgctgc tgcgcgcaga
      841 gccctacccc acgtcgcgtt atggcagcca gtgcatgcag cccaacaaca tcatgggcat
      901 cgagaacatc tgcgagctgg cagcccgcct cctcttcagc gccgtcgagt gggcccgcaa
      961 catcccgttc ttcccggatc tgcagatcac ggaccaggtg tctctgctgc gcctcacctg
     1021 gagcgagctg ttcgtgctca acgcggccca gtgctccatg cccctgcacg tggcgccgct
     1081 gctggccgca gccggcctgc acgcctcgcc catgtccgcg gaccgcgtcg tggccttcat
     1141 ggaccacatc cgcatctttc aggaacaggt ggagaagctc aaggcgctgc acgtcgactc
     1201 tgccgagtac agctgcctca aagccatcgt gctattcacg tcagatgctt gtggcctgtc
     1261 ggatgctgcc cacatcgaaa gcctgcagga gaaatcacag tgtgccctgg aggagtatgt
     1321 gagaagccag taccccaacc agcccagccg ctttggcaaa ctgctgctgc gattgccctc
     1381 tcttcgcaca gtgtcctcct ctgtcatcga gcaactcttc ttcgtacgtt tggtaggtaa
     1441 aactcccatc gaaactctca tccgagatat gttgctgtca gggagcagtt tcaactggcc
     1501 ttacatgtcc atccagtgtt cctagacttt gggtgtttcc cacccaatcc tgctccctga
     1561 ctccctagag actaagagga ctctccctga ccaaggacta aaaagccttt ggggatgctg
     1621 gtatgatgga ccaggcaggc caggcagacg ggaggagggc tgggaacaag agcagcccac
     1681 tctgcaggaa tgcaacctga gctgcaaacc aggagaaaag gagactcatt taggatctga
     1741 tctgtaagta cattggaaag gaaagaaaaa ggacctcgtg tctggtgaga aaatgaaaaa
     1801 aaaaaaaaaa aaaagaacga tttggaagag aggaccatga gaaatttaat aaaatagatg
     1861 gaccttccag gatttattgt ggatggatgt ggatatattc tgtacagaaa actactcata
     1921 tggaagtgga ctgaatccta tgtagaaaca tacactgaac attgttattc attttgtaaa
     1981 atactagtgt ttattttcat tttttgtaaa atttaaacat cgtatgcgca taaacaaaaa
     2041 tgaacaagaa ttagggggaa ataacatttt ccaaataatt ataaaaaatt tgtcctgtgt
     2101 ctatgtatct atatctgttt tgtatttttt ctggttccaa accagatttc ctgtgattct
     2161 atactaataa tttttgatat aaccctttgc ttcttataat gagtgcgata tatgttgtcg
     2221 aggctgttct tcaagaatta aaattgaagt gaaaatttaa acaaaaataa aagaatttag
     2281 caaaa
//
