LOCUS       NM_001410445            3398 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus neuropeptide Y receptor Y2 (Npy2r), transcript variant
            5, mRNA.
ACCESSION   NM_001410445
VERSION     NM_001410445.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3398)
  AUTHORS   Liu,M., Nair,A., Coria,N., Linderman,S.W. and Anderson,D.J.
  TITLE     Encoding of female mating dynamics by a hypothalamic line attractor
  JOURNAL   Nature 634 (8035), 901-909 (2024)
   PUBMED   39142338
REFERENCE   2  (bases 1 to 3398)
  AUTHORS   Bolivar,S., Sanz,E., Ovelleiro,D., Zochodne,D.W. and Udina,E.
  TITLE     Neuron-specific RNA-sequencing reveals different responses in
            peripheral neurons after nerve injury
  JOURNAL   Elife 12, 91316 (2024)
   PUBMED   38742628
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3398)
  AUTHORS   Schappe,M.S., Brinn,P.A., Joshi,N.R., Greenberg,R.S., Min,S.,
            Alabi,A.A., Zhang,C. and Liberles,S.D.
  TITLE     A vagal reflex evoked by airway closure
  JOURNAL   Nature 627 (8005), 830-838 (2024)
   PUBMED   38448588
REFERENCE   4  (bases 1 to 3398)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 3398)
  AUTHORS   Lovelace,J.W., Ma,J., Yadav,S., Chhabria,K., Shen,H., Pang,Z.,
            Qi,T., Sehgal,R., Zhang,Y., Bali,T., Vaissiere,T., Tan,S., Liu,Y.,
            Rumbaugh,G., Ye,L., Kleinfeld,D., Stringer,C. and Augustine,V.
  TITLE     Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce
            syncope
  JOURNAL   Nature 623 (7986), 387-396 (2023)
   PUBMED   37914931
REFERENCE   6  (bases 1 to 3398)
  AUTHORS   Naveilhan,P., Hassani,H., Canals,J.M., Ekstrand,A.J., Larefalk,A.,
            Chhajlani,V., Arenas,E., Gedda,K., Svensson,L., Thoren,P. and
            Ernfors,P.
  TITLE     Normal feeding behavior, body weight and leptin response require
            the neuropeptide Y Y2 receptor
  JOURNAL   Nat Med 5 (10), 1188-1193 (1999)
   PUBMED   10502824
REFERENCE   7  (bases 1 to 3398)
  AUTHORS   Naveilhan,P., Neveu,I., Arenas,E. and Ernfors,P.
  TITLE     Complementary and overlapping expression of Y1, Y2 and Y5 receptors
            in the developing and adult mouse nervous system
  JOURNAL   Neuroscience 87 (1), 289-302 (1998)
   PUBMED   9722158
REFERENCE   8  (bases 1 to 3398)
  AUTHORS   Besirli,C.G., Gong,T.W. and Lomax,M.I.
  TITLE     The Atp1b3 gene for Na,K-ATPase beta 3 subunit maps to mouse
            chromosome 9, and a related gene, Atp1b3-rs, maps to mouse
            chromosome 3
  JOURNAL   Mamm Genome 9 (2), 171-172 (1998)
   PUBMED   9457684
REFERENCE   9  (bases 1 to 3398)
  AUTHORS   Lutz,C.M., Frankel,W.N., Richards,J.E. and Thompson,D.A.
  TITLE     Neuropeptide Y receptor genes on human chromosome 4q31-q32 map to
            conserved linkage groups on mouse chromosomes 3 and 8
  JOURNAL   Genomics 41 (3), 498-500 (1997)
   PUBMED   9169155
  REMARK    Erratum:[Genomics 1997 Sep 1;44(2):251-2]
REFERENCE   10 (bases 1 to 3398)
  AUTHORS   Nakamura,M., Aoki,Y. and Hirano,D.
  TITLE     Cloning and functional expression of a cDNA encoding a mouse type 2
            neuropeptide Y receptor
  JOURNAL   Biochim Biophys Acta 1284 (2), 134-137 (1996)
   PUBMED   8914576
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091478.6.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995048.2354762.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               AC091478.6         94211-94475         c
            266-3398            AC091478.6         84759-87891         c
FEATURES             Location/Qualifiers
     source          1..3398
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 36.49 cM"
     gene            1..3398
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="neuropeptide Y receptor Y2"
                     /db_xref="GeneID:18167"
                     /db_xref="MGI:MGI:108418"
     exon            1..265
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /inference="alignment:Splign:2.1.0"
     exon            266..3398
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..1458
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="isoform 1 is encoded by transcript variant 5;
                     neuropeptide Y receptor type 2; Y2 receptor; NPY-Y2
                     receptor"
                     /codon_start=1
                     /product="neuropeptide Y receptor type 2 isoform 1"
                     /protein_id="NP_001397374.1"
                     /db_xref="GeneID:18167"
                     /db_xref="MGI:MGI:108418"
                     /translation="MGPVGAEADENQTVEVKVEPYGPGHTTPRGELPPDPEPELIDST
                     KLVEVQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTL
                     CLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKI
                     SKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTV
                     YSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQRRHKMTKMLVCVVVV
                     FAVSWLPLHAFQLAVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRK
                     AFLSAFRCEQRLDAIHSEVSMTFKAKKNLEVKKNNGPTDSFSEATNV"
     regulatory      3379..3384
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="hexamer: AATAAA"
     polyA_site      3398
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="major polyA site"
ORIGIN      
        1 actcctaccc ggggctctga gctgtgcagt gcggggtccc tgatcgagtg gctttagagg
       61 tccaccgaga agccgagcag gcacagcatt gcagctgttc cgctttgccg ctcctgcttc
      121 tgatctcact tgctggctca caccaaatcg gacctgcttt gggtgcctcc caggactgtc
      181 tccagactgg ctgtttagat aatcccttgc ttgaaattcc tggattcctc atctgagaag
      241 gaacgcgcaa gagtcaatac agtaaattct tgtgttattt acaggccaag tgagagtgaa
      301 ctggttctga agatgggccc ggtaggtgca gaggcagatg agaatcaaac tgtagaagtg
      361 aaagtggagc cctatgggcc agggcacact actcctagag gtgagttgcc ccctgatccg
      421 gagccggagc tcatagacag caccaaactg gtcgaggtgc aggtgatcct catattggcc
      481 tactgctcca tcatcttgct aggggtagtt ggcaactccc tggtaatcca tgtggtaatc
      541 aaattcaaga gcatgcgcac agtaaccaac ttttttattg ccaacctggc tgtggcggat
      601 cttttggtga acaccctgtg cctgccattc actcttacct ataccttgat gggagagtgg
      661 aaaatgggtc cggtcttgtg ccatttggtg ccctatgccc agggtctggc ggtacaagtg
      721 tccacaataa ctttgacagt cattgctctg gaccgccatc gttgcattgt ctaccacctg
      781 gagagcaaga tctccaagcg aatcagcttc ctgatcattg gcctggcctg gggcatcagc
      841 gctctgctgg caagtccact ggccatcttc cgggaatact ccctgattga gatcattcct
      901 gactttgaga ttgtggcctg taccgagaag tggcctgggg aagagaagag tgtgtatggt
      961 acagtctaca gcctttccac cctgctcatc ctgtacgttt tgcctctggg catcatatct
     1021 ttctcctaca cccgtatctg gagtaagctg aggaaccacg tcagtcctgg agctgcaagt
     1081 gaccattacc atcagcgaag gcacaaaatg accaaaatgc tggtgtgcgt ggtagtggtg
     1141 tttgcagtca gctggctacc cctccacgcc ttccaactcg ctgtggacat cgacagccac
     1201 gtcctggacc tgaaggagta caaactcatc ttcaccgtgt tccacattat cgccatgtgc
     1261 tccacctttg ccaaccccct tctctatggt tggatgaata gcaactacag aaaagctttc
     1321 ctctcggcct tccgctgtga gcagaggttg gatgccattc actcggaggt gtctatgacc
     1381 ttcaaggcta aaaagaacct ggaagtcaaa aagaacaatg gccccactga ctctttttcg
     1441 gaggctacca atgtgtaagg acacaggtgt gaaagcacat gggtgaattg taaccagcgc
     1501 tgccaatctg gttagggaag gttttctggc cagtgcatgc agacctccca ttgtattgac
     1561 tcaaaaagca acagaaccga agccccagca gttttatttc tggaaaactg gctggcagaa
     1621 ggaggtaaaa ataaacagat tgccatggca caacgttctg attaccgatg cttggattgt
     1681 aggttgaatt atgagtagag aagggaagga aaacagaaca aggagttggc accagcatgg
     1741 ttaaaaggga gaagtaagtg ttatctctga gagcacagta ggatctgcat caggcacact
     1801 gtggactcca tgggctccct catcacttga tgaaaagctg ctaaacaact cagatttccc
     1861 tagggagcta caggctctct gttagggtgt tttggtttta ttgtctttcc taagatgaaa
     1921 cccaaatgag aatgctatag gtaaacatgg cttgctacct aaggcggtga cttcaagata
     1981 acgtcaagag aataaacaca tttgctatac gagtaatgtt ttggcaatga tgggagagat
     2041 tcttatataa tcagtgagca attagttgtt gttcagatca aatgcactac tgttgaaagt
     2101 ttgtttttta gttcagaatc aaaatctgaa attatcatac tgaaaaggaa tgaaaacaat
     2161 tgctttattt ctgttatagc cattcctgct ttaggtagat actgtttgga tgacaagcga
     2221 gcaactcagc tcttctgttt cttgctaact gctaaagcct tttggaacca cacaactttt
     2281 gttaccattc ctgcatgaga gcaaacaaag ttcacactaa aagttaaatc agactaaaac
     2341 ataattttgt aacaatttga gtttagttgt aaaaaattga ccccctccac cacagctcta
     2401 acatgtttac agacactgta gaactatctt ctttggagtt catccacaat agaccaattt
     2461 aagttaagta aaaatataat ttcactaaag tgaacccatt tggtaagaaa tctccaaaac
     2521 tgagtttatt ccactttgaa aattttgttt ttatccacaa atttcacata aatgttctct
     2581 tttttaaatg actatatttt tggtaacata aatacatata caaaacaaaa gcatatctat
     2641 aaatagggaa gcattagaaa attttattta atagttttat gaatatagct tttatttcaa
     2701 aggtacccag ccaaagataa ttaaaactct attttgttca cacagaaaag tacgaaaaat
     2761 gagatgttaa aatagttgca cttctctgga tgctgacgtt tcagtgtagg catatttttt
     2821 gtaaatatgg cagaatctgt gagtatattc ctcacaattt agaaatattt gatgtagtct
     2881 aatatttagt tatgatatta attttgtata tatatttaaa tctcagactc tggctgttat
     2941 taaattcctt tcagtgtgga aataaaagat tggtctcaaa gtgaattgtt cttctagagt
     3001 actgaaaagg aataaaacac cagaagaaaa aaatgaatct aaggtggaac gggaagtcca
     3061 ccttatacac tgctgtctga agtgaatcgt tgaactataa aagacagtct ttcctgttgg
     3121 actctgcaca gtcatctgaa gaagcttttt actttctatg tgtaagatac ttgcttaaga
     3181 tcttagtaga aggttgttgt gaagtcttta tgccccttgc agatttccta tcctgtacaa
     3241 aacctgtctg ttactgtgac tccggctgtg atggtaaatt attggaatcc aattagtgat
     3301 tcaattaaca tatttgtgat tgagttcata tgtcaactca gtattaaagc atcttttatg
     3361 tgctggtttt aatgtcaaaa taaaaagaat ttgaggaa
//
