LOCUS       NM_001410443            3379 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus neuropeptide Y receptor Y2 (Npy2r), transcript variant
            3, mRNA.
ACCESSION   NM_001410443 XM_006501116
VERSION     NM_001410443.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3379)
  AUTHORS   Liu,M., Nair,A., Coria,N., Linderman,S.W. and Anderson,D.J.
  TITLE     Encoding of female mating dynamics by a hypothalamic line attractor
  JOURNAL   Nature 634 (8035), 901-909 (2024)
   PUBMED   39142338
REFERENCE   2  (bases 1 to 3379)
  AUTHORS   Bolivar,S., Sanz,E., Ovelleiro,D., Zochodne,D.W. and Udina,E.
  TITLE     Neuron-specific RNA-sequencing reveals different responses in
            peripheral neurons after nerve injury
  JOURNAL   Elife 12, 91316 (2024)
   PUBMED   38742628
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3379)
  AUTHORS   Schappe,M.S., Brinn,P.A., Joshi,N.R., Greenberg,R.S., Min,S.,
            Alabi,A.A., Zhang,C. and Liberles,S.D.
  TITLE     A vagal reflex evoked by airway closure
  JOURNAL   Nature 627 (8005), 830-838 (2024)
   PUBMED   38448588
REFERENCE   4  (bases 1 to 3379)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 3379)
  AUTHORS   Lovelace,J.W., Ma,J., Yadav,S., Chhabria,K., Shen,H., Pang,Z.,
            Qi,T., Sehgal,R., Zhang,Y., Bali,T., Vaissiere,T., Tan,S., Liu,Y.,
            Rumbaugh,G., Ye,L., Kleinfeld,D., Stringer,C. and Augustine,V.
  TITLE     Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce
            syncope
  JOURNAL   Nature 623 (7986), 387-396 (2023)
   PUBMED   37914931
REFERENCE   6  (bases 1 to 3379)
  AUTHORS   Naveilhan,P., Hassani,H., Canals,J.M., Ekstrand,A.J., Larefalk,A.,
            Chhajlani,V., Arenas,E., Gedda,K., Svensson,L., Thoren,P. and
            Ernfors,P.
  TITLE     Normal feeding behavior, body weight and leptin response require
            the neuropeptide Y Y2 receptor
  JOURNAL   Nat Med 5 (10), 1188-1193 (1999)
   PUBMED   10502824
REFERENCE   7  (bases 1 to 3379)
  AUTHORS   Naveilhan,P., Neveu,I., Arenas,E. and Ernfors,P.
  TITLE     Complementary and overlapping expression of Y1, Y2 and Y5 receptors
            in the developing and adult mouse nervous system
  JOURNAL   Neuroscience 87 (1), 289-302 (1998)
   PUBMED   9722158
REFERENCE   8  (bases 1 to 3379)
  AUTHORS   Besirli,C.G., Gong,T.W. and Lomax,M.I.
  TITLE     The Atp1b3 gene for Na,K-ATPase beta 3 subunit maps to mouse
            chromosome 9, and a related gene, Atp1b3-rs, maps to mouse
            chromosome 3
  JOURNAL   Mamm Genome 9 (2), 171-172 (1998)
   PUBMED   9457684
REFERENCE   9  (bases 1 to 3379)
  AUTHORS   Lutz,C.M., Frankel,W.N., Richards,J.E. and Thompson,D.A.
  TITLE     Neuropeptide Y receptor genes on human chromosome 4q31-q32 map to
            conserved linkage groups on mouse chromosomes 3 and 8
  JOURNAL   Genomics 41 (3), 498-500 (1997)
   PUBMED   9169155
  REMARK    Erratum:[Genomics 1997 Sep 1;44(2):251-2]
REFERENCE   10 (bases 1 to 3379)
  AUTHORS   Nakamura,M., Aoki,Y. and Hirano,D.
  TITLE     Cloning and functional expression of a cDNA encoding a mouse type 2
            neuropeptide Y receptor
  JOURNAL   Biochim Biophys Acta 1284 (2), 134-137 (1996)
   PUBMED   8914576
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091478.6.
            
            On Aug 8, 2022 this sequence version replaced XM_006501116.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D86238.1, SRR14995048.2153836.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-265               AC091478.6         94211-94475         c
            266-3379            AC091478.6         84759-87872         c
FEATURES             Location/Qualifiers
     source          1..3379
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 36.49 cM"
     gene            1..3379
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="neuropeptide Y receptor Y2"
                     /db_xref="GeneID:18167"
                     /db_xref="MGI:MGI:108418"
     exon            1..265
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /inference="alignment:Splign:2.1.0"
     exon            266..3379
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..1439
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="isoform 1 is encoded by transcript variant 3;
                     neuropeptide Y receptor type 2; Y2 receptor; NPY-Y2
                     receptor"
                     /codon_start=1
                     /product="neuropeptide Y receptor type 2 isoform 1"
                     /protein_id="NP_001397372.1"
                     /db_xref="GeneID:18167"
                     /db_xref="MGI:MGI:108418"
                     /translation="MGPVGAEADENQTVEVKVEPYGPGHTTPRGELPPDPEPELIDST
                     KLVEVQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTL
                     CLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKI
                     SKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTV
                     YSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQRRHKMTKMLVCVVVV
                     FAVSWLPLHAFQLAVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRK
                     AFLSAFRCEQRLDAIHSEVSMTFKAKKNLEVKKNNGPTDSFSEATNV"
     regulatory      3360..3365
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="hexamer: AATAAA"
     polyA_site      3379
                     /gene="Npy2r"
                     /gene_synonym="NPY2-R"
                     /note="major polyA site"
ORIGIN      
        1 actcctaccc ggggctctga gctgtgcagt gcggggtccc tgatcgagtg gctttagagg
       61 tccaccgaga agccgagcag gcacagcatt gcagctgttc cgctttgccg ctcctgcttc
      121 tgatctcact tgctggctca caccaaatcg gacctgcttt gggtgcctcc caggactgtc
      181 tccagactgg ctgtttagat aatcccttgc ttgaaattcc tggattcctc atctgagaag
      241 gaacgcgcaa gagtcaatac agtaagccaa gtgagagtga actggttctg aagatgggcc
      301 cggtaggtgc agaggcagat gagaatcaaa ctgtagaagt gaaagtggag ccctatgggc
      361 cagggcacac tactcctaga ggtgagttgc cccctgatcc ggagccggag ctcatagaca
      421 gcaccaaact ggtcgaggtg caggtgatcc tcatattggc ctactgctcc atcatcttgc
      481 taggggtagt tggcaactcc ctggtaatcc atgtggtaat caaattcaag agcatgcgca
      541 cagtaaccaa cttttttatt gccaacctgg ctgtggcgga tcttttggtg aacaccctgt
      601 gcctgccatt cactcttacc tataccttga tgggagagtg gaaaatgggt ccggtcttgt
      661 gccatttggt gccctatgcc cagggtctgg cggtacaagt gtccacaata actttgacag
      721 tcattgctct ggaccgccat cgttgcattg tctaccacct ggagagcaag atctccaagc
      781 gaatcagctt cctgatcatt ggcctggcct ggggcatcag cgctctgctg gcaagtccac
      841 tggccatctt ccgggaatac tccctgattg agatcattcc tgactttgag attgtggcct
      901 gtaccgagaa gtggcctggg gaagagaaga gtgtgtatgg tacagtctac agcctttcca
      961 ccctgctcat cctgtacgtt ttgcctctgg gcatcatatc tttctcctac acccgtatct
     1021 ggagtaagct gaggaaccac gtcagtcctg gagctgcaag tgaccattac catcagcgaa
     1081 ggcacaaaat gaccaaaatg ctggtgtgcg tggtagtggt gtttgcagtc agctggctac
     1141 ccctccacgc cttccaactc gctgtggaca tcgacagcca cgtcctggac ctgaaggagt
     1201 acaaactcat cttcaccgtg ttccacatta tcgccatgtg ctccaccttt gccaaccccc
     1261 ttctctatgg ttggatgaat agcaactaca gaaaagcttt cctctcggcc ttccgctgtg
     1321 agcagaggtt ggatgccatt cactcggagg tgtctatgac cttcaaggct aaaaagaacc
     1381 tggaagtcaa aaagaacaat ggccccactg actctttttc ggaggctacc aatgtgtaag
     1441 gacacaggtg tgaaagcaca tgggtgaatt gtaaccagcg ctgccaatct ggttagggaa
     1501 ggttttctgg ccagtgcatg cagacctccc attgtattga ctcaaaaagc aacagaaccg
     1561 aagccccagc agttttattt ctggaaaact ggctggcaga aggaggtaaa aataaacaga
     1621 ttgccatggc acaacgttct gattaccgat gcttggattg taggttgaat tatgagtaga
     1681 gaagggaagg aaaacagaac aaggagttgg caccagcatg gttaaaaggg agaagtaagt
     1741 gttatctctg agagcacagt aggatctgca tcaggcacac tgtggactcc atgggctccc
     1801 tcatcacttg atgaaaagct gctaaacaac tcagatttcc ctagggagct acaggctctc
     1861 tgttagggtg ttttggtttt attgtctttc ctaagatgaa acccaaatga gaatgctata
     1921 ggtaaacatg gcttgctacc taaggcggtg acttcaagat aacgtcaaga gaataaacac
     1981 atttgctata cgagtaatgt tttggcaatg atgggagaga ttcttatata atcagtgagc
     2041 aattagttgt tgttcagatc aaatgcacta ctgttgaaag tttgtttttt agttcagaat
     2101 caaaatctga aattatcata ctgaaaagga atgaaaacaa ttgctttatt tctgttatag
     2161 ccattcctgc tttaggtaga tactgtttgg atgacaagcg agcaactcag ctcttctgtt
     2221 tcttgctaac tgctaaagcc ttttggaacc acacaacttt tgttaccatt cctgcatgag
     2281 agcaaacaaa gttcacacta aaagttaaat cagactaaaa cataattttg taacaatttg
     2341 agtttagttg taaaaaattg accccctcca ccacagctct aacatgttta cagacactgt
     2401 agaactatct tctttggagt tcatccacaa tagaccaatt taagttaagt aaaaatataa
     2461 tttcactaaa gtgaacccat ttggtaagaa atctccaaaa ctgagtttat tccactttga
     2521 aaattttgtt tttatccaca aatttcacat aaatgttctc ttttttaaat gactatattt
     2581 ttggtaacat aaatacatat acaaaacaaa agcatatcta taaataggga agcattagaa
     2641 aattttattt aatagtttta tgaatatagc ttttatttca aaggtaccca gccaaagata
     2701 attaaaactc tattttgttc acacagaaaa gtacgaaaaa tgagatgtta aaatagttgc
     2761 acttctctgg atgctgacgt ttcagtgtag gcatattttt tgtaaatatg gcagaatctg
     2821 tgagtatatt cctcacaatt tagaaatatt tgatgtagtc taatatttag ttatgatatt
     2881 aattttgtat atatatttaa atctcagact ctggctgtta ttaaattcct ttcagtgtgg
     2941 aaataaaaga ttggtctcaa agtgaattgt tcttctagag tactgaaaag gaataaaaca
     3001 ccagaagaaa aaaatgaatc taaggtggaa cgggaagtcc accttataca ctgctgtctg
     3061 aagtgaatcg ttgaactata aaagacagtc tttcctgttg gactctgcac agtcatctga
     3121 agaagctttt tactttctat gtgtaagata cttgcttaag atcttagtag aaggttgttg
     3181 tgaagtcttt atgccccttg cagatttcct atcctgtaca aaacctgtct gttactgtga
     3241 ctccggctgt gatggtaaat tattggaatc caattagtga ttcaattaac atatttgtga
     3301 ttgagttcat atgtcaactc agtattaaag catcttttat gtgctggttt taatgtcaaa
     3361 ataaaaagaa tttgaggaa
//
