LOCUS       NM_008721               1522 bp    mRNA    linear   ROD 23-DEC-2022
DEFINITION  Mus musculus neural proliferation, differentiation and control 1
            (Npdc1), mRNA.
ACCESSION   NM_008721
VERSION     NM_008721.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1522)
  AUTHORS   Gao H, Ni N, Zhang D, Wang Y, Tang Z, Sun N, Ju Y, Dai X, Zhang Y,
            Liu Y and Gu P.
  TITLE     miR-762 regulates the proliferation and differentiation of retinal
            progenitor cells by targeting NPDC1
  JOURNAL   Cell Cycle 19 (14), 1754-1767 (2020)
   PUBMED   32544377
  REMARK    GeneRIF: miR-762 regulates the proliferation and differentiation of
            retinal progenitor cells by targeting NPDC1.
REFERENCE   2  (bases 1 to 1522)
  AUTHORS   Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK,
            Carpenter DA, Johnson DK, Rinchik EM and Culiat CT.
  TITLE     Nell1-deficient mice have reduced expression of extracellular
            matrix proteins causing cranial and vertebral defects
  JOURNAL   Hum Mol Genet 15 (8), 1329-1341 (2006)
   PUBMED   16537572
REFERENCE   3  (bases 1 to 1522)
  AUTHORS   Evrard C, Caron S and Rouget P.
  TITLE     Functional analysis of the NPDC-1 gene
  JOURNAL   Gene 343 (1), 153-163 (2004)
   PUBMED   15563841
  REMARK    GeneRIF: Upstream sequence of the mouse NPDC-1 gene delineated two
            regions involved in its negative and positive transcriptional
            regulation.
REFERENCE   4  (bases 1 to 1522)
  AUTHORS   Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber
            G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong
            WH and Cepko CL.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   5  (bases 1 to 1522)
  AUTHORS   Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B and Melton DA.
  TITLE     Global expression analysis of gene regulatory pathways during
            endocrine pancreatic development
  JOURNAL   Development 131 (1), 165-179 (2004)
   PUBMED   14660441
REFERENCE   6  (bases 1 to 1522)
  AUTHORS   Qu X, Zhang C, Zhai Y, Xing G, Wei H, Yu Y, Wu S and He F.
  TITLE     Characterization and tissue expression of a novel human gene npdc1
  JOURNAL   Gene 264 (1), 37-44 (2001)
   PUBMED   11245976
REFERENCE   7  (bases 1 to 1522)
  AUTHORS   Galiana E, Vernier P, Dupont E, Evrard C and Rouget P.
  TITLE     Identification of a neural-specific cDNA, NPDC-1, able to
            down-regulate cell proliferation and to suppress transformation
  JOURNAL   Proc Natl Acad Sci U S A 92 (5), 1560-1564 (1995)
   PUBMED   7878019
REFERENCE   8  (bases 1 to 1522)
  AUTHORS   Galiana E, Bernard R, Borde I, Rouget P and Evrard C.
  TITLE     Proliferation and differentiation properties of bipotent glial
            progenitor cell lines immortalized with the adenovirus E1A gene
  JOURNAL   J Neurosci Res 36 (2), 133-146 (1993)
   PUBMED   7903403
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ057319.1, BB870287.1, AK146466.1 and AI839809.1.
            
            [WARNING] On May 2, 2023 this sequence was replaced by NM_008721.5.
            
            On Aug 10, 2013 this sequence version replaced NM_008721.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003320.1, AK146466.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                CJ057319.1         3-29
            28-112              BB870287.1         8-92
            113-1272            AK146466.1         2-1161
            1273-1522           AI839809.1         1-250               c
FEATURES             Location/Qualifiers
     source          1..1522
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2"
     gene            1..1522
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /note="neural proliferation, differentiation and control
                     1"
                     /db_xref="GeneID:18146"
                     /db_xref="MGI:MGI:1099802"
     exon            1..316
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..1203
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /note="neural proliferation differentiation and control
                     protein 1; neural proliferation differentiation control-1
                     protein; neural proliferation, differentiation and control
                     gene 1"
                     /codon_start=1
                     /product="neural proliferation differentiation and control
                     protein 1 precursor"
                     /protein_id="NP_032747.2"
                     /db_xref="CCDS:CCDS15771.1"
                     /db_xref="GeneID:18146"
                     /db_xref="MGI:MGI:1099802"
                     /translation="MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDATTCPG
                     SLDCALKRRAKCPPGAHACGPCLQSFQEDQRGFCVPRKHLSSGEGLPQPRLEEEIDSL
                     AQELALKEKEAGHSRLTAQPLLEAAQKLLEPAATLGFSQWGQRLEPGLPSTHGTSSPI
                     PHTSLSSRASSGPVQMSPLEPQGRHGNGLTLVLILAFCLASSAALAVAALCWCRLQRE
                     IRLTQKADYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPK
                     ELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHSTLSAPVPGPHSLPPLQ"
     exon            317..463
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            464..604
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            605..778
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            779..845
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            846..933
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1013
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1110
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1506
                     /gene="Npdc1"
                     /gene_synonym="NPDC-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggcgcactc ccgacacttt tctctggccg ccgcgcctcc atcccatccc ggatccattg
       61 ccgcaacgtc agcgccaccg cctcctcttt tcctcttcct cctccgcccc tctcgcttcc
      121 cggcttctcc agtcgcagtt cccggagtgg gtaccgagcc cggggccgtg gggtgccatg
      181 ctgcccgggt agcggcgctg aagcatggcg acgcccgtcc ctccgccttc cccgcggcac
      241 ctgcggctgc tacggctgct gctctccggc ctcatcctgg gagcggccct gaatggtgcc
      301 accgcccgcc gcccggatgc taccacctgt cctggaagcc tggattgtgc actgaagagg
      361 cgggcaaaat gcccaccagg ggcacatgcc tgtggaccat gccttcagtc cttccaggaa
      421 gaccagcgag ggttctgtgt gccaaggaaa cacctatctt ctggggaggg cctgccccag
      481 cccagactgg aagaggagat cgattctctg gcccaggaac tggcactgaa ggagaaggag
      541 gcggggcact caaggctgac cgcacagccc ttgcttgagg ctgcgcagaa gctcctggag
      601 cctgcagcta ccctgggatt ctcacagtgg ggtcaacgac tggagcccgg gctcccctct
      661 actcatggaa cctcttcacc tataccccat acttccttga gttcccgagc atcctctgga
      721 cctgtgcaga tgtccccgct ggagccccag ggaaggcatg ggaatggcct cacccttgtg
      781 ctgatcctgg ctttctgctt agcaagctca gccgccctgg ctgtggcagc cctctgctgg
      841 tgtaggcttc agcgagagat ccgcctgact cagaaggctg actatgctgc cacagctaag
      901 gggcccactt caccttcaac accacgaatc tcgcctgggg atcagcggct ggcacacagt
      961 gctgagatgt atcattatca gcaccagaga cagcagatgc tgtgcctgga gcggcataag
     1021 gaacctccaa aggaactaga gtcagcttcc tccgatgagg aaaatgaaga tggcgacttc
     1081 actgtgtatg aatgcccagg cctggcgcca acaggggaga tggaggtgcg caacccactg
     1141 tttgaccatt ccacgctgtc agcaccagtg cctggtcccc attccttgcc gccgctgcag
     1201 tgactcctag gcccacatgc ctgcagccca cagcccacca gtggggacga gcgagtcctg
     1261 gtgttcccca tggaaaagag cagcattgtg acccccgcat gcttttggca ggagggaggc
     1321 gccacccctg gactcccttg ccagggagat tctccgcctt atgtgggaga tctagcatct
     1381 gcttgcacat tctctgtctg gtatgaaccc tcaaactgga gatccaagtc caggaaccct
     1441 agagcccagg catggataga gagttttgga gacaaaagcc aattaaagtt tttttcaaac
     1501 ctgtgaaaaa aaaaaaaaaa aa
//
