LOCUS       NM_027744               1412 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus NADP+ dependent oxidoreductase domain containing 1
            (Noxred1), mRNA.
ACCESSION   NM_027744 XM_127023 XM_907160 XM_994742
VERSION     NM_027744.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1412)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC125331.1.
            
            On or before Oct 30, 2006 this sequence version replaced
            XM_127023.7, XM_907160.2, XM_994742.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC125331.1, AK017096.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1412
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 41.42 cM"
     gene            1..1412
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /note="NADP+ dependent oxidoreductase domain containing 1"
                     /db_xref="GeneID:71275"
                     /db_xref="MGI:MGI:1918525"
     exon            1..27
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            28..156
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            157..334
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..1280
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /note="pyrroline-5-carboxylate reductase-like protein
                     C14orf148 homolog"
                     /codon_start=1
                     /product="NADP-dependent oxidoreductase domain-containing
                     protein 1"
                     /protein_id="NP_082020.1"
                     /db_xref="CCDS:CCDS36502.1"
                     /db_xref="GeneID:71275"
                     /db_xref="MGI:MGI:1918525"
                     /translation="MEMLEDLESLRFEFGIPEEERYWLYLQGRYRGLMIKGCAHAAFF
                     CKMFSTLSNLLQNLPRTIHPRTVSFDNAATEDELLTVGIIGCGHLGKQLTNVLLKTVP
                     IPAENLQISTRRPESLGELRKLGVRCVYDNAAVASWAKVLFLCCLPAQLPNICLEIQS
                     KLNKHCTVYSFVSAIPLPRLKSLLNHTNILRPQYQFAEDYDNIWGENEEVPIALQDTT
                     IIRGTCPYNNLGGVILNVKWIEGLCYALINACTSRSVFHSQVLKLLNKLLLPMHLESC
                     TTDPESCPQFNLTDFMSKSYVKNLYQKRPFPWFDLTTVQLKETPFSQHISATPSLQDH
                     ISLLYCEVFGLTISEEELPYISTVIRPLVEEK"
     exon            335..534
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            535..715
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            716..867
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1090
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1412
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1318..1323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1341
                     /gene="Noxred1"
                     /gene_synonym="4933437F05Rik"
                     /note="major polyA site"
ORIGIN      
        1 caagtgggtg aaggggaagg agaccaggaa cagttggtgg tctttgtcat ggaattgaat
       61 atgacctggc ccaggagtga gccccataag gaaggccagg agcaggtgga gcagttacag
      121 gcctagctac tgaacgacac caagacatcc aaccagggat tggtgctttg gaagtggaca
      181 tggaaatgct agaagacctt gagtctctga ggtttgagtt tgggattcca gaggaagaac
      241 gttactggct gtacttacag ggccgttatc ggggattgat gatcaagggc tgtgcccatg
      301 cagccttctt ctgcaaaatg ttctctactt tgagcaactt attgcagaat ctgccacgca
      361 caatacatcc ccggactgtg tcatttgata acgccgctac tgaggatgaa ctgctaaccg
      421 tgggcatcat tgggtgtggc caccttggaa agcagctgac taatgtattg ctgaaaaccg
      481 tccctatccc tgccgagaac ctgcagatct ccactaggag gccagagtcc ctgggtgagt
      541 tacggaaact aggggtccgg tgcgtctatg acaacgctgc tgtggcgagc tgggccaaag
      601 tgttgttcct ctgctgtctg cctgcccagc tgcctaatat ctgcctagaa attcaatcca
      661 aactcaacaa gcactgcacc gtgtacagct ttgtatccgc cattccgcta cccaggttga
      721 aaagtttact gaaccacacc aatatcctga ggccccagta ccaatttgct gaggattatg
      781 acaacatctg gggagagaat gaggaggtcc caattgctct ccaagataca acgattatcc
      841 ggggtacctg cccctacaat aatcttgggg gagtaatcct taatgtcaag tggatagagg
      901 ggctgtgcta tgccctcatc aatgcctgta cgtcaaggag cgtgtttcac tcacaggtgc
      961 tgaagcttct aaacaaactg cttctcccta tgcacttaga aagctgcacg acagacccag
     1021 aatcctgccc ccagtttaat ttaacagatt tcatgagcaa aagctacgtc aaaaacttgt
     1081 atcaaaaaag gcctttcccc tggtttgatc tgactactgt gcaactcaag gaaactcctt
     1141 ttagccagca catctcagcc actccttctc ttcaggacca cattagtctt ttgtactgtg
     1201 aagtatttgg cctcaccata agcgaagaag aattgcctta tatttccaca gttatccggc
     1261 ccctagtaga ggagaaatga cagagagcca tgagttctgc ttgatacccg agtgaagaat
     1321 aaaataggag atcctcctct atatgtcagt attcttgggt gtttcttaga aacaatctag
     1381 tccattgctt cccccaagcc cttgtcaaca ca
//
