LOCUS       NM_001029877            8372 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus NOVA alternative splicing regulator 2 (Nova2), mRNA.
ACCESSION   NM_001029877 XM_357715
VERSION     NM_001029877.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8372)
  AUTHORS   Ibrahim,L.A., Wamsley,B., Alghamdi,N., Yusuf,N., Sevier,E.,
            Hairston,A., Sherer,M., Jaglin,X.H., Xu,Q., Guo,L.,
            Khodadadi-Jamayran,A., Favuzzi,E., Yuan,Y., Dimidschstein,J.,
            Darnell,R.B. and Fishell,G.
  TITLE     Nova proteins direct synaptic integration of somatostatin
            interneurons through activity-dependent alternative splicing
  JOURNAL   Elife 12, e86842 (2023)
   PUBMED   37347149
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8372)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8372)
  AUTHORS   Knupp,D., Cooper,D.A., Saito,Y., Darnell,R.B. and Miura,P.
  TITLE     NOVA2 regulates neural circRNA biogenesis
  JOURNAL   Nucleic Acids Res 49 (12), 6849-6862 (2021)
   PUBMED   34157123
  REMARK    GeneRIF: NOVA2 regulates neural circRNA biogenesis.
REFERENCE   4  (bases 1 to 8372)
  AUTHORS   Johnson,V., Junge,H.J. and Chen,Z.
  TITLE     Temporal regulation of axonal repulsion by alternative splicing of
            a conserved microexon in mammalian Robo1 and Robo2
  JOURNAL   Elife 8, e46042 (2019)
   PUBMED   31392959
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8372)
  AUTHORS   Saito,Y., Yuan,Y., Zucker-Scharff,I., Fak,J.J., Jereb,S.,
            Tajima,Y., Licatalosi,D.D. and Darnell,R.B.
  TITLE     Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory
            Neurons Regulates Cortical Development and Cerebellar Function
  JOURNAL   Neuron 101 (4), 707-720 (2019)
   PUBMED   30638744
  REMARK    GeneRIF: NOVA2 controls unique RNA splicing programs in inhibitory
            and excitatory neurons during cortical development.
REFERENCE   6  (bases 1 to 8372)
  AUTHORS   Ule,J., Ule,A., Spencer,J., Williams,A., Hu,J.S., Cline,M.,
            Wang,H., Clark,T., Fraser,C., Ruggiu,M., Zeeberg,B.R., Kane,D.,
            Weinstein,J.N., Blume,J. and Darnell,R.B.
  TITLE     Nova regulates brain-specific splicing to shape the synapse
  JOURNAL   Nat Genet 37 (8), 844-852 (2005)
   PUBMED   16041372
REFERENCE   7  (bases 1 to 8372)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 8372)
  AUTHORS   Ule,J., Jensen,K.B., Ruggiu,M., Mele,A., Ule,A. and Darnell,R.B.
  TITLE     CLIP identifies Nova-regulated RNA networks in the brain
  JOURNAL   Science 302 (5648), 1212-1215 (2003)
   PUBMED   14615540
  REMARK    GeneRIF: CLIP (cross-linking and immunoprecipitation) reveals Nova
            coordinately regulates a biologically coherent set of RNAs encoding
            multiple components of the inhibitory synapse, an observation that
            may relate to the cause of abnormal motor inhibition in POMA
REFERENCE   9  (bases 1 to 8372)
  AUTHORS   Polydorides,A.D., Okano,H.J., Yang,Y.Y., Stefani,G. and
            Darnell,R.B.
  TITLE     A brain-enriched polypyrimidine tract-binding protein antagonizes
            the ability of Nova to regulate neuron-specific alternative
            splicing
  JOURNAL   Proc Natl Acad Sci U S A 97 (12), 6350-6355 (2000)
   PUBMED   10829067
REFERENCE   10 (bases 1 to 8372)
  AUTHORS   Yang,Y.Y., Yin,G.L. and Darnell,R.B.
  TITLE     The neuronal RNA-binding protein Nova-2 is implicated as the
            autoantigen targeted in POMA patients with dementia
  JOURNAL   Proc Natl Acad Sci U S A 95 (22), 13254-13259 (1998)
   PUBMED   9789075
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ126741.1, CJ126972.1, BF466030.1, AC170864.2 and BF455773.1.
            
            On Sep 11, 2010 this sequence version replaced NM_001029877.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927936.3177263.1,
                                           SRR10662773.960126.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: lack of evidence for use of
                                                upstream AUG
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                CJ126741.1         1-94
            95-504              CJ126972.1         54-463
            505-920             BF466030.1         1-416               c
            921-7990            AC170864.2         122025-129094       c
            7991-8372           BF455773.1         17-398              c
FEATURES             Location/Qualifiers
     source          1..8372
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.41 cM"
     gene            1..8372
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="NOVA alternative splicing regulator 2"
                     /db_xref="GeneID:384569"
                     /db_xref="MGI:MGI:104296"
     exon            1..277
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1671
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="neuro-oncological ventral antigen 2"
                     /codon_start=1
                     /product="RNA-binding protein Nova-2"
                     /protein_id="NP_001025048.2"
                     /db_xref="CCDS:CCDS20882.2"
                     /db_xref="GeneID:384569"
                     /db_xref="MGI:MGI:104296"
                     /translation="MEPEAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAA
                     GSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEK
                     VREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQS
                     GAWVQLSQKPEGINLQERVVTVSGEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVA
                     GPVANSNPTGSPYASPADVLPAAAAASAAAASGLLGPAGLAGVGAFPAALPAFSGTDL
                     LAISTALNTLASYGYNTNSLSLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGDA
                     GAGPGAGAAPPPPPPPGALGSFALAAAANGYLGAGAGGAAGAGGAPLVAAAAAAGAAG
                     GFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLP
                     GTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKVG"
     exon            278..421
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /inference="alignment:Splign:2.1.0"
     exon            422..588
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /inference="alignment:Splign:2.1.0"
     exon            589..8372
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1995..2000
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="hexamer: AACAAA"
     polyA_site      2006
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="major polyA site"
     regulatory      7699..7704
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="hexamer: GATAAA"
     polyA_site      7717
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="major polyA site"
     regulatory      8200..8205
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="hexamer: AATGAA"
     polyA_site      8239
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
     regulatory      8333..8338
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="hexamer: AATGAA"
     regulatory      8338..8343
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
                     /note="hexamer: ACTAAA"
     polyA_site      8353
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
     polyA_site      8372
                     /gene="Nova2"
                     /gene_synonym="Gm1424"
ORIGIN      
        1 atgaggatga tggccgccgg cgcggtgcac ggcctcttca cggcctccgc ggccccgcag
       61 ccgccgccgc ccccgccgcc gccgccgccg ccgcagcccc agcctcccca gcagccgtcg
      121 ccgccgccac agcagccgcc gccgccgccg cagccgccgc agcagcagca gccgccgccc
      181 caggcccccc ccatggagcc cgaggccccg gattcccgca agagacccct cgagacgccc
      241 cccgaggtgg tctgcaccaa gcgcagcaac acgggagagg aaggcgagta cttcctgaag
      301 gtgctcatcc ccagctacgc cgccggctca atcatcggca aaggtggcca gaccatcgtg
      361 cagctccaga aggagacagg agccaccatc aagctgtcta agtccaaaga cttctaccca
      421 ggaactacag aacgggtatg cctagtacag ggcacggcag aggccttgaa tgctgtccac
      481 agctttatcg cagaaaaggt ccgagaaatc cctcaagcga tgaccaagcc tgaggtggtc
      541 aacatccttc aaccccaaac cacgatgaac cccgacagag ccaagcaggc caagctcatc
      601 gtccccaaca gcacggcagg actgatcatc ggtaagggag gagcgaccgt gaaggcggtg
      661 atggaacagt ccggcgcgtg ggtgcagctg tcgcagaagc ccgagggcat caacctgcaa
      721 gagcgcgtgg tgaccgtgag cggcgagccg gagcaggtgc acaaggccgt gagcgccatc
      781 gtgcagaagg tacaggaaga cccgcagagc agcagctgcc tcaacatcag ctacgccaac
      841 gtggcggggc ccgtggccaa ctccaacccc accggctcgc cctacgccag cccggccgac
      901 gtgctccccg ccgcggccgc cgcctctgcc gccgccgcct cgggtctgct aggccccgcg
      961 gggctggcgg gcgtgggcgc cttccccgcc gcgctgcccg ccttctcggg caccgacctg
     1021 ctggccatca gcacggcgct caacacgttg gccagctacg gctacaacac caactcgctc
     1081 agcctgggcc tcaactcggc cgccgcctcc ggcgtcctgg ccgccgtagc cgcaggcgcc
     1141 aaccccgccg ccgccgcagc agccaacctc ctggcgtcct acgcggggga cgccggggcg
     1201 gggccggggg cgggggcagc accgccaccg ccaccgcccc ccggagcgct gggttccttc
     1261 gctctggccg cggctgccaa tggctacctc ggtgcgggcg cggggggcgc ggctggagcg
     1321 gggggcgcgc ccctggtggc cgccgcggct gcggccgggg ctgccggcgg cttcctgacg
     1381 gccgagaagc tggcggccga gagcgccaag gagctggtgg agatcgcggt gcccgagaac
     1441 ctggtggggg ccatcctggg caaagggggc aagacgctgg tggagtacca ggagctgacg
     1501 ggcgcgcgca tccagatctc caagaagggc gagttcctgc ccggcacgcg gaaccggcgg
     1561 gtcaccatca cgggcagccc cgcggccacg caagccgctc aatacctcat cagccagcgg
     1621 gtcacctacg agcagggggt gagggcttca aacccacaga aagtgggatg aggcctgtgg
     1681 tgtgcgtccc caccccctcc cgctcctctt ccctcctctt ccccctcttc cccaactccc
     1741 gccagacttc agcttggtgt gactcctgct tggcttggaa tggggctggg gtaggcctgg
     1801 ctgcaccctc ccttctggta gtcataggca ggattgagtg acgactgagg agggggcttt
     1861 tgagccccct ccccagcctt gaattgaccc cctccttcct ccctccctgt gcttgactgg
     1921 gcctgaccca cctctcccgg ggtccaggtc tatgtgatat ctgtatatat tgcattttgt
     1981 tgattttaat agaaaacaaa gcgttatttt ctctttcttt ccctcctttt ttttcttttt
     2041 aactttttct ccttcttctt cttctttttt ttttttttga taaggacccc ccctccttta
     2101 taagattttt gttgttgttg ttaacatatg ggaggagggg agggagcctt caggtcacct
     2161 ggaatgaggt gcctctccca aacacaacat cctgcctctc tgattgcagt tccagaacct
     2221 ggggaagaga cccaagtagg agtagaggta gccacccagg agtcagagct gaagtgaggg
     2281 gtttcaaaca tagacactca ccccggtccg agcccccagg atccccacat ttcctcagct
     2341 cctctctccc cctgcagtat tccctggaat ggaagtgtaa ctttctccgt tgagcagagc
     2401 tattcctgct gggaatgact ccagctctgg gatgctgcag gtcctgtgag ccacactatt
     2461 gtgcgaggcc caggagcagc tggctgtaac atcttagggc tcttcctaga ggaacgaggg
     2521 tccgtgttgt gatgtcactg aatcaagtat ttaccgggtg cttccagtaa ctccctatga
     2581 tgtcatagga aggatttcct cagaggctac ttccggtact ggttagagaa aatcatttcc
     2641 tgtgaggtcc caacaaaagg cctcaaaggt cgcttctgta gatggcagag gcatgtactt
     2701 cctgtggaat ctcgaggtca cttcctgtgg catcataggg atgaagcatg cgcttccggt
     2761 gttggacagt ggccagtccc taagattccc cctcctccct ctacactcct ctttggtggg
     2821 tgttggccct gggtgagggg gaatccttag gaagaatggg acttgggttt aacatggaag
     2881 attgtaaggg ggaaaaaaaa tcctgtcagg gttatctctg tccagacacg ctatctgtga
     2941 acttgccttg acaggcacga atgggagacg aagctagtga aaatgaatga ttgctaaaga
     3001 tccccccttc cccacccctg ccttttgtgt gcatgcctgt gtctacgtgg tttcatttca
     3061 ttgatggatg agccaaatgt atggtggctc tgtcaggcca gtgtgatctg gtgtagagtt
     3121 cagtgagcct tgcaaagttt agggtatctc gggctgaaat gccttgcgca gtctgccgaa
     3181 tttgaagctt ggcggcttcc agggagctgg tgtatgttga cgatcttgat tggtcagaaa
     3241 tgttccagtg tgctcagcct tattagactc agaggagcta ggagattctc tggaagtacg
     3301 acaaaccagg ctaccctggg agttgtcttg ggagtggctc acttggcatg gtggctctgg
     3361 tcagctctga agagtcaggg cctgaaaaac ctatagacta ggattgctga gacatccccc
     3421 tgtcccctaa catcgccccc tctctgttgg agagcacctt caatttcctc caaccccaag
     3481 cagggtcctc agagccctgt ctccatcatc agcatctctg ggggagggac accccatgcc
     3541 cactccctcc tccatccatt cctaggtctt ccagaccctg ctcttctcca tggctttggg
     3601 gatatctggc ctccttgttt ctatccctac aaaggagctg ggaggagaga gaccacccag
     3661 atgatgccta ctacagcctt caagcctggg aggccccccc taccccgtgc tagagagcca
     3721 ccccaaaatc aaaatgtgaa aatccctaga aagcaatagc cttcgaggta cctcgcactg
     3781 actccccctc ccccagccct tccacaggaa tgggaggcta tggcttgagc actggggtga
     3841 cttttttcca tgtcctcatc tccccagtga ggggcaggcc ccatttcctt gacacacccc
     3901 catctcccac ctcctatcgc tgctgcccct ttatccctaa tctccaccct gagcccagat
     3961 ggagatttta gtgccaaaac aattcttgat accactttgt acatatcttc tacagttggg
     4021 gctgctgaga ttggaggtgg gggccggccc acagggccat tgctcccctc cacctcttaa
     4081 atgaccttac agtatttcat gtagctccac ctgcatgtgg gtagtaaagt atctagctgg
     4141 aatccccccc cccccgcgcg cgcgcgcccg taaaaccctc aggctccatg aggaggggaa
     4201 ggaatagggg tgaagcaatg tccaggatgg gtaggtggga taaagacact ctatttgtaa
     4261 atcatctgtg ccctctcttg gacagcctgc tttccataag cccattggct ggagtctggg
     4321 tccattccct gtgtgacatg cccgtgttct cagggatcca ttcccccacc agccagggct
     4381 atctgaaaag tagtttgcta gcttagtaag ctggtccact caccatgttg gtgagtgagg
     4441 agtggcacac ctccccaccc gcattgtacc ctgggaaatt ccatcatctt ccctatccct
     4501 tgaaaatccc ttctgaaatc caacctcagt ctttctgtac tgtagttggt ccagaaggga
     4561 tacataatgc aggtcaggga tgagaattac ttttaaaata atagtaataa caaagctcat
     4621 tccccgcccc ttctgcctgt tagccaatca gatcgcaaag gatctgaccg gcctccttgc
     4681 atcccactct tcagcaccag taggtgctta gtaagatagt taagtgttgc ctgcattgaa
     4741 ctgtctcatc tgccctcctg cttccgatac ccctgccccc agcattctcc tctgcctccc
     4801 taaggcccac tgggttttcc tcttgtggtt gcccctcccc cacggttctc tgtcctgtct
     4861 ctacctttgt ctgtattctt ctcctcctga attctcgact ctcatttccc ctttaaaagc
     4921 aaaaagtgcc aaacttcctc ggaactgagc cgatctgggg tggggggatg aggatcttag
     4981 atggagggag gaaaccacct ctcttagagg ggggggggcc ttaagaggca aagaaaacac
     5041 tttaggatgc tgagctaaat tggatcccct tcctcgttcc tctcaccctg agttttttct
     5101 tagaatcttt ataagaaaaa aagaaaaaga aaaaaaaaac attttcaact aacccctact
     5161 tttttggatt cctctccccc aaattccacc agccaaggag aacccccttt gcctttctct
     5221 gggcaaatcc attgaaactg gggatggaga gaaagactcc accctctttt gctagcccaa
     5281 cggggtggct gctggggaag gacctcaaag catgacaaga ggggttcgaa agtgccaaat
     5341 ttcaccttct tcatcctgtc ttgggcaggg ctctgagcca gcctgcccgg tcatcagctt
     5401 tgccctctcc cagccatctc tccgtgggcg ggaaaatttt gccgcaataa ttagcagggc
     5461 agggatcgga aggcagggat tttgcagtct ctgtctgtac tggacttgga ggtgggaatt
     5521 atgggagcgt ggcaagagtc tttaaaatgg ttggggacct atactcggaa tattacggta
     5581 ccacttgttt tcccacggta tttttttttt tttcctctct ccactcttga ccaaccaaat
     5641 cccttggaat atcggacctc cgttcccacc tcagttctgt ttcttcagcc cgcccctgtg
     5701 gccaacacca tccttattac tttatggcta gctggtctcc agctatttga aaaaggagag
     5761 gaggttctcc cttgcatgga ctcttgctgt ttcgagccta acaggttaat ttgcaaaagc
     5821 gttcaccaga gcagcggtga aggtggcaat ctaggcgtcc aggatgctcc actaggttgt
     5881 acacctgtcg gacagccaga caggccttct gcccagggca tcagccccaa gcgccatccg
     5941 gaattgaggc cggcgtcgtc aaaacctgaa ctggttgtca ccatggggga gcacagaacc
     6001 gcaataccca ggtcgggggg cagagaagcc tggtttacgc tttgtggagt gtggacaccg
     6061 agccttgcgg tccgagccct ctctccacca cagtcagcgg tctcgatgcc ccagctggtg
     6121 tgtccgttcc atcgggtccc cacggctatc atcggaggca tagacaacct cccgcttagt
     6181 ggcaggaggg agggaaagtc tctggagggt ggtggtggtg aagactgctg gtttttaacc
     6241 ccttctcaga cagtctagga cactggtctc cttagaatta atatagggag accctcctcc
     6301 ttcctccctt ccccccaccc cctcccaccc cccacaaaac caccaacctc tcatcttcta
     6361 agtgactcca tcaccaccgg ccaccacggg aacctgcggc ctcattgctc cagcccgccc
     6421 cactcgaccg tcagactcgc tccatcgaac tcttttaatt aaccctttct gtgttcatcc
     6481 cacggaaaac ctgtgtgtct ggcagggaag ccaggggggt ggatgctaag ggcagttgct
     6541 accttccctc catctcctcc cagcgcccat gcctccccat gccatgcccc aatccttatc
     6601 cctcacccct taggatccgc ctcccctggg ggcacaggga tcttctagaa atacctttgc
     6661 agtttggctt tgcaaaggcc ggcctagggg gcgtggcctc cccatcggag cgctcactct
     6721 gactgtcctc cccgttgccc ccacccactc cccacgcctt cattgtaaat agtcactttt
     6781 gtacttggtt tgagccaggc gacgtgggga gtgtctctct ctttctctct ctctctctct
     6841 ctctctctct ctctctctct ctctctctct ctcttatttg tgttggcatc tcaactcctg
     6901 gaggcatggt ccacatcccg gttcgatttg ggagaaaccc aaggtgtgcc ccgccaaaat
     6961 gttaaggatc tcgagagaac agtattaact cggacagctg gctggggtgc acaggtcctc
     7021 cgaccgggag gagggagaga aagcctttgt tcttgagatc ctgtgaaatg ggttcgttct
     7081 ccgagctttc tgaagaacct tggtggagct gagaattgaa tctctcctct gcttcctctg
     7141 ttggaggctg gctcaaaaag aatggctttg ggatggggca gtctttggag aattgactgc
     7201 tgaattcttc ctgggacctg aagctaacct ctggtaggct tgttttcttg caaagaggta
     7261 gtcagatgaa catccctctc caaccgttag aggaaaggtc caagccccgc ggctggccct
     7321 gcctgctgcc actctgccgc attatagttt gcgggtggga cgggcagtga agtggccatg
     7381 cctccagttt ctccattcaa acccctctta actgatttcc ttccatcctc tttgaccagc
     7441 gccgccgccc acttcctctc tgccacctcc agaagctctt ggctggggtc accgcactct
     7501 cttccctatc cccccatcgc catgcctggg ccatgcccac atctcccacc cactcaccca
     7561 ccccccagtg tccgttgtgt gacctagtgc accatgtatt agcttccatg gacccccccc
     7621 cccacctacc cactccccgc tcccaccaca cccctccccc accccttctc cctcggcgac
     7681 ttcacctttt tttgccgcga taaacgtcat ctcagcatct gtgtctaatg ttgtcttttt
     7741 tgcttggcat cacacacgcc ttcttaaccc atccccttcc ctctccctcc tccctgacac
     7801 ctccaccctc atcctcaact cttttcccct ttgtccccca tcccccaccc agggctctgg
     7861 gcatttaagg gaggggggac ctttaaggat ggtctcagag gagggagggg tgtgttctct
     7921 gatttgggtg aacaaatgag agtaagcatg gccaaagaaa gtaagtgttt caaggctgaa
     7981 cttgtccatc caatatccag tcctgggaac catggtcacc agcagccaca catacacaga
     8041 acccacagac agctcctgga cacccgtgtc cactgggagc agctcctcga ctccagtagc
     8101 accagaatag cccggggcca ggtgcttgga gcgatgcaag accccacctc agacccctga
     8161 gattttgccc atctgagcca ccaaccttgc caactgtaga atgaaaaggt ttttttttta
     8221 aatgttattt ctacatcaat tgtttatgct tgaatttaat acatcattca ctttttaaag
     8281 ggtttattaa gcacctatgt gtaaggcact gttctaagtg ccaaagttag aaaatgaact
     8341 aaacagaccc aaacatgtct gccttcaggg aa
//
