LOCUS       NM_133831               1572 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus NOP53 ribosome biogenesis factor (Nop53), mRNA.
ACCESSION   NM_133831
VERSION     NM_133831.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1572)
  AUTHORS   Sasaki,M., Kawahara,K., Nishio,M., Mimori,K., Kogo,R., Hamada,K.,
            Itoh,B., Wang,J., Komatsu,Y., Yang,Y.R., Hikasa,H., Horie,Y.,
            Yamashita,T., Kamijo,T., Zhang,Y., Zhu,Y., Prives,C., Nakano,T.,
            Mak,T.W., Sasaki,T., Maehama,T., Mori,M. and Suzuki,A.
  TITLE     Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via
            nucleolar RPL11
  JOURNAL   Nat Med 17 (8), 944-951 (2011)
   PUBMED   21804542
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1572)
  AUTHORS   Okahara,F., Itoh,K., Nakagawara,A., Murakami,M., Kanaho,Y. and
            Maehama,T.
  TITLE     Critical role of PICT-1, a tumor suppressor candidate, in
            phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic
            transformation
  JOURNAL   Mol Biol Cell 17 (11), 4888-4895 (2006)
   PUBMED   16971513
  REMARK    GeneRIF: These results suggest that PICT-1 plays a role in
            phosphatidylinositol 3,4,5-trisphosphate signals through
            controlling PTEN protein stability.
REFERENCE   3  (bases 1 to 1572)
  AUTHORS   Hong,H.K., Chakravarti,A. and Takahashi,J.S.
  TITLE     The gene for soluble N-ethylmaleimide sensitive factor attachment
            protein alpha is mutated in hydrocephaly with hop gait (hyh) mice
  JOURNAL   Proc Natl Acad Sci U S A 101 (6), 1748-1753 (2004)
   PUBMED   14755058
REFERENCE   4  (bases 1 to 1572)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 1572)
  AUTHORS   Chae,T.H., Allen,K.M., Davisson,M.T., Sweet,H.O. and Walsh,C.A.
  TITLE     Mapping of the mouse hyh gene to a YAC/BAC contig on proximal
            Chromosome 7
  JOURNAL   Mamm Genome 13 (5), 239-244 (2002)
   PUBMED   12016511
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY283382.1, AK169290.1 and AI850210.1.
            
            On Apr 30, 2009 this sequence version replaced NM_133831.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017637.2, AK146916.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BY283382.1         1-41
            42-1555             AK169290.1         2-1515
            1556-1572           AI850210.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1572
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 8.64 cM"
     gene            1..1572
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /note="NOP53 ribosome biogenesis factor"
                     /db_xref="GeneID:68077"
                     /db_xref="MGI:MGI:2154441"
     exon            1..279
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            280..344
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            345..453
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            454..653
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            654..724
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            725..820
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            821..925
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1126
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1302
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1369
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1446
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1503
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1558
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1539..1544
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /note="hexamer: AATAAA"
     polyA_site      1558
                     /gene="Nop53"
                     /gene_synonym="5330430H08Rik; 9430097C02Rik; Gltscr2;
                     PICT-1"
                     /note="major polyA site"
ORIGIN      
        1 gcacgttcca aaccggatat cggagttaga gcgactaagc tcttccttta agaagatggc
       61 tgcgggtggt aacagggacg gtgagaagcg cggctcgaga agccaggcgg actctggctt
      121 cctggggctg cggccgacct cggtggatcc cgctctgagg cggcggcggc ggggccccag
      181 aaacaagaag cgcggctgga ggaggctcgc cgaggagccg ctggggttag aggtcgacca
      241 gttcctggaa gacgtccggc tacaggagcg cacgaccggt ggcttgttgg cagaggcccc
      301 aaacgaaaag ctcttcttcg tggacacagg attcaagaga aaagaaccaa gaaagaagag
      361 gaccttggtc cagaagaagt cacagcgtct ccagaaaccc ttacgggttg accttgccct
      421 tgagaatcat tctaagatcc ctgctcccaa agacatcctc gcacatcagg tccctaatgc
      481 caagaagctc aggcgaaagg aggagttatg ggagaaactg gcaaagcagg gcgaactgcc
      541 cagggatgtg cgcaaggcac aggcccgact ccttagccct cccacaccaa aggccaaacc
      601 tgggccccag gacatcattg agcgaccctt ctatgacctc tggaacccag acaaccctct
      661 ggacacgcct ttgattggtc aggatgcatt ttttctggaa cagaccaaga agaaaggcgt
      721 gaggcggcca caacgcctcc acatcaagcc ttcccaggtg cctgcagtgg aggtgattcc
      781 tgcaggagcc tcctacaacc caacctttga agatcaccag gccctgcttc gagaggccca
      841 tgaggtggag ctgcagcgtg agaaagaggc agaaaagctg gagcgacagc tggccctgcc
      901 cacctcagag caagctgcca cccaggagtc cgtgtttcgg gagatgtgtg agggcctgct
      961 ggaggagtct gatggtgagg atgagcatga ggcaggccgt gccgggcagc cagaggctgg
     1021 tgatgggacc accgagatct cacccactgg tgctgctggt cctgagaaga ggatggagaa
     1081 gaagacggag cagcagcggc ggcgggagaa agctgctcgc aagctgcggg tgcagcaggc
     1141 tgcactgagg gcagcccggc ttcagcacca agaacttttc aggctgcgtg ggatcaaggc
     1201 ccaggtggcc cgaaggctgg cagaactggc acgccggagg gagcagcggc gcatacggcg
     1261 actggcagag gctgacaagc cccgaaggct gggacggctc aagtaccagg ctcctgacat
     1321 tgatgtgcag ctcagctctg agttgtctgg ctcactcagg acactgaagc cagaaggtca
     1381 cattctccga gacaggttca agagcttcca gaagagaaat atgattgagc cccgagaacg
     1441 agccaagttc aagcgcaaat acaaagtgaa gctggtggag aagcgggcct accgtgagat
     1501 tcagttgtag ctgtgcagat gtcggagccc cgcccctcaa taaagttctg tgaccaaaaa
     1561 aaaaaaaaaa aa
//
