LOCUS       NM_001033457            3542 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleolar protein with MIF4G domain 1 (Nom1),
            transcript variant 1, mRNA.
ACCESSION   NM_001033457 XM_131953 XM_908010
VERSION     NM_001033457.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3542)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3542)
  AUTHORS   Symmons,O., Pan,L., Remeseiro,S., Aktas,T., Klein,F., Huber,W. and
            Spitz,F.
  TITLE     The Shh Topological Domain Facilitates the Action of Remote
            Enhancers by Reducing the Effects of Genomic Distances
  JOURNAL   Dev Cell 39 (5), 529-543 (2016)
   PUBMED   27867070
REFERENCE   4  (bases 1 to 3542)
  AUTHORS   DiTommaso,T., Jones,L.K., Cottle,D.L., Gerdin,A.K., Vancollie,V.E.,
            Watt,F.M., Ramirez-Solis,R., Bradley,A., Steel,K.P., Sundberg,J.P.,
            White,J.K. and Smyth,I.M.
  CONSRTM   WTSI Mouse Genetics Program
  TITLE     Identification of genes important for cutaneous function revealed
            by a large scale reverse genetic screen in the mouse
  JOURNAL   PLoS Genet 10 (10), e1004705 (2014)
   PUBMED   25340873
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3542)
  AUTHORS   Anderson,E., Devenney,P.S., Hill,R.E. and Lettice,L.A.
  TITLE     Mapping the Shh long-range regulatory domain
  JOURNAL   Development 141 (20), 3934-3943 (2014)
   PUBMED   25252942
REFERENCE   6  (bases 1 to 3542)
  AUTHORS   Amano,T., Sagai,T., Tanabe,H., Mizushina,Y., Nakazawa,H. and
            Shiroishi,T.
  TITLE     Chromosomal dynamics at the Shh locus: limb bud-specific
            differential regulation of competence and active transcription
  JOURNAL   Dev Cell 16 (1), 47-57 (2009)
   PUBMED   19097946
REFERENCE   7  (bases 1 to 3542)
  AUTHORS   Clark,R.M., Marker,P.C. and Kingsley,D.M.
  TITLE     A novel candidate gene for mouse and human preaxial polydactyly
            with altered expression in limbs of Hemimelic extra-toes mutant
            mice
  JOURNAL   Genomics 67 (1), 19-27 (2000)
   PUBMED   10945466
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148406.1 and AC171500.2.
            
            On Mar 30, 2007 this sequence version replaced NM_001033457.1.
            
            Transcript Variant: This variant (1) is the protein-coding
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.41997.1, AK148406.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-937               AK148406.1         5-941
            938-977             AC171500.2         158255-158294
            978-2263            AK148406.1         982-2267
            2264-2291           AC171500.2         169569-169596
            2292-2846           AK148406.1         2296-2850
            2847-3542           AC171500.2         174125-174820
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 15.0 cM"
     gene            1..3542
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /note="nucleolar protein with MIF4G domain 1"
                     /db_xref="GeneID:433864"
                     /db_xref="MGI:MGI:1861749"
     exon            1..977
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1105
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1301
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1625
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            1626..1736
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..1904
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2026
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2159
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            2160..2291
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            2292..2401
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     exon            2402..3542
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2850
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /note="major polyA site"
     regulatory      3291..3296
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /note="hexamer: AATAAA"
     polyA_site      3309
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
     regulatory      3454..3459
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
                     /note="hexamer: AATAAA"
     polyA_site      3476
                     /gene="Nom1"
                     /gene_synonym="D5Kng1; Gm1040"
ORIGIN      
        1 ttccggaagt gatgccgcgg aacgtcccgg aagttaacgg cgtctatagg catggggctt
       61 gtgagttgtg gtgtagagca atggcacatg ctctcttgaa acgtagcggc gtccgccgcg
      121 gtctgggcgg cagggagggt cccctgaaac ggctgcggct ggccgtggaa gacttcgtgc
      181 ggactacctc cgagagcgaa gcctgcgaga gccgcagcgc tgtggcgcgc tcccggcccg
      241 gcggccgaaa gagccgcaag gagcttcgta aggagaagcg acacctgagg aaagcgcggc
      301 gcctgcagag gacagtaggc tccgggtcag gggaccaagg ggggaatgtc ggccttaacg
      361 atggcccgga gactcgacga ccgcccactg aggtgagacc gacgcccgcc aaggccacag
      421 caacccctgc caaggccagt gccccctcca ctaacaccaa ggcctcggcg gcccagccga
      481 aggccaaggc taaaggtgct cctggaaagc ctggtcccgc caccgccacc gcccggaagc
      541 gggcacttct agcggccaac gaggaggagg accgagagat ccgaaagctg gaacggtgcc
      601 tcggcctcca caagcgtaag aagaagggcg atggtagctc ggtgccgctc agcttcgcgc
      661 gcgacggtct ggactacatc ctgggggccc tggaatgtgg gagcggcggc ggcctgtacg
      721 aaagcagcga ggaagaggag gaagaaaagt tggagactgg acagacagtc ttggagagtg
      781 acctagagag caattctaaa gaaagtgagg aggacccaga ctggcaagtg ctgcaggagg
      841 atcaggaaga tgtaaactcg aaaaggagag gagaagcaga aagtgggact cggggaaata
      901 aagggactaa gaaagtgcgt tttgcagaag ttgtagaaaa gagcagaagc tcttcggaag
      961 atgacataga acagcaggag agtcactctg ttgaaagtgg tgaaaagtac atccctcctc
     1021 ggctgaggaa cgaggaggta atagatgtcc acaagaaaga agagctagac aggctcaaga
     1081 aacatgttaa aggcctaatt aacaggttga gtgagccaaa catggcttct ataagtgggc
     1141 agctagagga gctgtacatg gcccacagca ggaaggacat gaacgatacc ctgaccactg
     1201 ccctcatgga tgcctgtgtc actgcctcag ccatgcccag cagactgatg atggagcatg
     1261 tcttcttagt cagcatcctc caccacacgg tcggaataga ggttggtgct tgcttccttg
     1321 aagctgtggt aaagaagttt gatgctatct atagagatgg aggtgagggg aaagaactgg
     1381 acaacctctt taccatgatt gcccatttgt acaacttcca cgtggtacag tctatcctca
     1441 tctttgacat tttaaagaag cttgttggaa cttttacgga aaaagacatt gagctgatcc
     1501 tgttgatgct gaaaaatgtg ggctttgcat tgagaaaaga tgacgccttg tcacttaagg
     1561 aactgatcac agaagcccag acccaggcca gtggtgcagg caacaagttt caggaccaga
     1621 acagggtacg gtttatgttg gaaacaatgc tggctctgaa gaacaatgac ctgcgtaaaa
     1681 tccctggtta taatcctgag cctgtggaaa aactgaagaa gttacaaaga actctggttc
     1741 gaaatgctgg ctcaggttct gagactcggc ttcgcatctc ctgggatggc atcttgaatg
     1801 cagagcagac tggtcgctgg tggattgtgg ggtctgcatg gagtgggacc ccaatgattg
     1861 acaacagtca tcacatacaa cttcagaagc cacttgcagg catggctagc tctaagatgc
     1921 tggagcttgc gaggaagcag agaatgaaca ctgatgtcag gaggatcata ttctgcactt
     1981 taatgacaag tgaggacttc ttggatgcct ttgaaaagct gctgaagctt ggactgaagg
     2041 accagcagga gagagagata gttcatatcc tcatggattg ctgtctgcaa gagaaaacct
     2101 acaacccttt ctatgctttc ctggccagca aattctgtga ctatgaaagg agattccaga
     2161 tgactttcca gttcagcata tgggacaaat ttcgggactt agaaaatttg ccagacacta
     2221 agttctcaaa tctggttcat ctgctggcac acttgttgag gacaaaatca cttccacttt
     2281 ctgttctaaa ggtagttgaa ttcagtgaat tggataaacc cagagttcac ttcctacgga
     2341 gggtgttgac tgcactgttg atggaaactg aagacgacga cttggctgta attttttcaa
     2401 gagtgtctga caacccaaag ctgggaatgt tgcgagaagg cctgaagctc ttcattggcc
     2461 acttcttact gaagcacaca caggctcacc agagtgctga ggaagccagt ctgctgagag
     2521 agaaggctgg ccttgcatct aagtctttac agggcaaagc catcctgaga atgtagccag
     2581 agtataggga gcatttgacc aagagatgtg gtttgtgaat tcaaggcagt cctgcctcta
     2641 agaacaggag gattatgcca tgctttgtca gggtttaaat attgtatttt cagattttta
     2701 gagtattatg tacttcaaat gtatatgtat gtatatagca ggtcagggga aagggggaga
     2761 aaagattaag ccatgaggag agggttggga ccataaattg atgactattt tttatcttct
     2821 aaaatgttgg ttaaaagttt aaaaactggg cacatggtgg cacgtgtctt tcattctagc
     2881 actcggggaa gcaggggcag gcagatctct gagttccagg ccagcctggt ctacatagtg
     2941 agttctagga cagccagagt aaattgtgtg acctatctca aaaaaaaaaa aaaaaaaaaa
     3001 gttctaatgc cttaagaaag tgtggtgctt aggctctgat atctcccact ccgaaatccc
     3061 actcacttca ggtaggtatt gagtacttgg gaagaagaga caaaaaagaa cagagataag
     3121 gagctggcaa gatggctcag ctggtaagag ctcggactgc tcttcaaaag gtcctgagtt
     3181 tcatatccca gcaacctcat ggtggctcac aaccacccgt aatgagatct aacgccctct
     3241 tctggtgtgt ctgaagacag ctacagtgta cttatgtata ataataaata aataaatctt
     3301 tggaccagag cgagcaggct cttaagtgag cagggttgac cagatcaagc ggagccaacc
     3361 agagcaagtg gaggtcctaa attcaattcc caacaactac atgaaggctc acaaccatct
     3421 ctacagctac agtgtactca tacacataaa ataaataaat ctttttttta aaaaaagaac
     3481 agataacatg attgtgttag gtaagggtag catgggctca cagactgaag aaggatgcat
     3541 gg
//
