LOCUS       NM_001159599            3756 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleolar protein 9 (Nol9), transcript variant 1,
            mRNA.
ACCESSION   NM_001159599
VERSION     NM_001159599.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3756)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3756)
  AUTHORS   Fujinami,H., Shiraishi,H., Hada,K., Inoue,M., Morisaki,I., Higa,R.,
            Shin,T., Kobayashi,T., Hanada,R., Penninger,J.M., Mimata,H. and
            Hanada,T.
  TITLE     CLP1 acts as the main RNA kinase in mice
  JOURNAL   Biochem Biophys Res Commun (2020) In press
   PUBMED   32081435
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 3756)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 3756)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK047599.1, AK164493.1, BC132099.1 and BC051109.1.
            
            On Mar 10, 2015 this sequence version replaced NM_001159599.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK157398.1, SRR7345562.1984642.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 AK047599.1         2-7
            7-337               AK164493.1         2-332
            338-2044            BC132099.1         322-2028
            2045-3756           BC051109.1         1915-3626
FEATURES             Location/Qualifiers
     source          1..3756
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 82.84 cM"
     gene            1..3756
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /note="nucleolar protein 9"
                     /db_xref="GeneID:74035"
                     /db_xref="MGI:MGI:1921285"
     exon            1..487
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..2179
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /EC_number="2.7.1.78"
                     /note="isoform 1 is encoded by transcript variant 1;
                     polynucleotide 5'-hydroxyl-kinase NOL9"
                     /codon_start=1
                     /product="polynucleotide 5'-hydroxyl-kinase NOL9 isoform
                     1"
                     /protein_id="NP_001153071.1"
                     /db_xref="CCDS:CCDS51389.1"
                     /db_xref="GeneID:74035"
                     /db_xref="MGI:MGI:1921285"
                     /translation="MAESEVLHRRAPSRSSWLRVRKARPHLLLSRRGRRRFGVLTRVE
                     LRRLRRRLLRAHALGGDWKQVAPAGAHVAVKCKLRARSRPAPRSPPTPSVPPAPCTAS
                     ATCSLLNPRNHSTPQSRAGRPVRKVSPNVTQPVRDLGSGRVLMMLPPGEGFTFSGICR
                     VTCVYGQLEVYGHIINQGQPPQDVFSVYTHSYLTINGVPYAEPEKSEKAIRREIRALL
                     KPYTKLDDRNWVVRYFPPLGSIMILERMQSRFVDFLKTYKCSSYVLLQENAPVRVNSE
                     FTTLKKIGIRRQKRKKAICLSESGLCALEELVSVSCDGCPVILLCGACDIGKSTFNRI
                     LINQLLNSIPGVDYLECDLGQTEFTPPGCVALLTITEPLLGPPYTHQRKPQRMVYYGK
                     MNCYNDYENYIDIVKYVFRDYKREFPLIINTMGWVSDNGLRLLVDLIRVLSPNYVVQL
                     YSDRCKFTPTLTSEYVELTDGLYTKSKIKRYRGFEIPEFGDNLEFTYEEKESSPLPVF
                     TGHVLLSVHSEFLSSKNEKNRAKYNRIFRDLAVLGYLSQLMLPVPESLSPLHSLTPYQ
                     VPFSAVAIRVLHADVAPTHILYAVNASWVGLCRIVDDMKGYTRGPILLAQNPICDCLG
                     FGICRGIDMDKRTYHILTPLPPEELKTVNCLLVGSISIPHCIFQNQPGPEGSVPYVTT
                     DYNLNIPGATEKIGEREYGKAFPRHKLRQRRK"
     exon            488..707
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            708..835
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            836..971
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1059
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1157
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1319
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1620
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1732
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1733..1910
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..2044
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..3742
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3717..3722
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3742
                     /gene="Nol9"
                     /gene_synonym="4632412I24Rik; 6030462G04Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagatcgtcc cgccggaggg gttccgggac aagcatggcg gagtcggagg tgttacaccg
       61 gcgggctccg agccgctctt cctggctgcg ggtacgcaaa gcccggcccc acctcctcct
      121 cagccgccgg ggccgccgtc ggtttggggt cctgacccga gtcgagctgc gacgcctgcg
      181 acggcggctg ctgcgggcac acgcgttagg cggggactgg aagcaggtcg cccccgcggg
      241 cgcgcacgtg gcggtaaagt gcaaactccg ggcccgcagc cggccggcgc cccgcagccc
      301 gcccacaccg agcgtcccgc ccgcgccatg caccgcgtcc gcgacctgca gcctgctcaa
      361 cccccgcaac cactccacgc cccagagccg ggccgggcgc cccgtgcgga aggtgtcccc
      421 gaacgtcacc cagcccgtgc gggacctggg ctcgggccgc gtgttgatga tgctgccgcc
      481 gggagagggt ttcactttca gtgggatctg ccgtgtgact tgcgtctacg gccagttgga
      541 agtatacggc catatcatca accaagggca gcctccccaa gatgtctttt ctgtctacac
      601 ccactcttac ctgaccatca atggggttcc gtacgcagaa cccgagaaaa gtgagaaggc
      661 gatcaggagg gagatccggg ccctgctcaa gccttacacg aaactagatg acagaaactg
      721 ggtggtgcgg tacttccctc ctctgggctc cattatgatt ctggaacgga tgcagtctcg
      781 ttttgtggac ttcctgaaga cctataagtg ctcctcatac gtgctcctgc aggagaacgc
      841 tcctgttcgg gtcaattctg agtttacaac tttgaagaaa attggcatca gaagacagaa
      901 gaggaagaaa gccatttgct tgagtgagag tggcctttgt gccctggaag agttagtcag
      961 cgtgtcctgt gatggctgcc ctgtcatcct gttgtgtggc gcttgtgaca ttggaaagtc
     1021 aacgttcaat agaatactga ttaaccagtt attaaatagc attcctgggg ttgactatct
     1081 ggaatgtgat ctggggcaga cggagttcac tcctcctggc tgtgtcgctt tacttaccat
     1141 cacagaacca cttctgggac cgccgtacac tcaccagagg aaaccacaga ggatggtgta
     1201 ctatgggaag atgaactgtt acaatgacta cgagaattac attgacatag taaaatacgt
     1261 gttcagagat tacaagagag agtttccact tatcatcaac acgatgggct gggtgtcaga
     1321 taatgggctg cggctgcttg tggacctgat ccgggtgctg tctcccaatt atgtcgttca
     1381 gttatattct gatcgctgta aatttacacc gacactgacc tccgaatacg tagagctcac
     1441 agatggcctg tatacaaaaa gcaagatcaa aagatatcga ggttttgaaa ttccagaatt
     1501 tggagacaat ttagaattta cttatgaaga gaaagagtct agtccacttc cagtcttcac
     1561 tggacatgta ctgctgtctg ttcactccga attcttaagt agtaaaaatg aaaagaacag
     1621 ggccaaatac aacaggattt ttcgagatct ggcagtgttg ggctacctta gccagctgat
     1681 gcttcccgtg ccagagtcac ttagtccttt gcacagcctg acgccctatc aggtcccctt
     1741 cagtgccgtc gctatccggg tcttgcatgc cgacgttgcg cctacccaca tactgtatgc
     1801 tgtgaatgcc agctgggtcg gcctttgcag gatcgtggat gatatgaaag gctacactcg
     1861 gggccccatc ctgcttgccc agaaccccat atgtgactgt ttgggctttg gtatctgcag
     1921 aggcattgac atggacaagc ggacctacca catcctcacc cctctacccc cagaagagtt
     1981 aaaaactgtg aactgtctgc tggttggttc catttccatc ccacattgta tttttcagaa
     2041 ccagcctggg cccgaagggt cagttcctta tgtcaccaca gattataatt taaatatccc
     2101 tggagcaaca gagaaaattg gagagagaga gtatggaaaa gcattcccta gacacaaatt
     2161 acggcaaaga agaaaataag cctgggaatg gagagacttt gctcccggga tgcctcgtcc
     2221 caggccgagt cagcagactg cgtgggctgt ggtgagtggg gctgtgtggc tgccgagctc
     2281 ctgctcctgc ccgctgttca cggaactgga aagtgtgctg tgcccctcca gtgtcttccc
     2341 tctgagacag gagggccttg tatcctacag ctctatctgg cctcaaactc tgggtatttc
     2401 aggcctgtgt taggacacca gctctcagac ttttcagctc tttggtctca aacttggccc
     2461 cagccctctt gacgactggt tgtcccggct gtggcgtgct tcctgagagc tgtgaagcag
     2521 tgaagaaagc cgtggtgtcc tcagaacagg cagaggaagg acagccttgc agttttccaa
     2581 gaaaatcggg accatgaaag tatggctaga aactgggcag caggctgacc cgcaggttct
     2641 catgtacagc gcacagactg ccgggggcct gagcaggctc agtgagaggc gtgttgagcc
     2701 atgtggacat tagcaaccag gtgccaactc cttggtctga tccttgggtg ccatcggatc
     2761 ttccagtgct gtaagcaagt cttagaagat tgtatttcat ctgttaattt cagggtcttt
     2821 tgaatcatga ggctttatgt tgaagaactt gctctgacat ccagaaagcc ccctggttaa
     2881 ttaaggaaac ccttggctcc ttaagtctgg gtttgctctc actgcccctt ccttgaggca
     2941 gtggatactg ccatggggcc ctccagcctg gagtggacac atacatgcct ggtgtcggca
     3001 aatcttggct atcgaggatt tctccgacag acccagaggc cactgcaggt ggatgttgtg
     3061 accaggagtg actgtgtcag gtcatttctg tggttgcaga gctgaggagc ttctcaggca
     3121 ggcatgatgg atctgtcaag actccacctt ccagcaggat catgaaagac caaggctgtg
     3181 gaaggcttac accattgctt acctccatct tgtctgtagc catgggagtg tgccagtctc
     3241 ctttgcttgg tgccatcttt gtggcagcct cagcatctga aaatcccatt aggcagagct
     3301 gctgcttccc cttccctgta gagcactcac taactggtcc ccaccgcccc ctcgcccagt
     3361 ctgtgtctca cttgagcttg tggtgagcct ttctgggagg gaggaggctc ttagcctgct
     3421 gcccaggcag gtctctgggc accgttggct ctcctgcctc gcagagagtt tgaagacagc
     3481 cttctaagac agcctttgtc acctttgtcc agttccccag atcttctggt cttcacagta
     3541 ctaaagatcg agtggggctg gagaggtggc tcagcagtta agagcactga ctgctctccc
     3601 agaggtcctg agttcaattc ccaacaacca catggtgact cacaaccatc tgcaatggga
     3661 tcggatgccc tcttctggtg tgtctgaagc tacagtgtac tcatgtacat aaaataaata
     3721 aatcttttaa agaaaataat aaaaaaaaaa aaaaaa
//
