LOCUS       NM_139236               4522 bp    mRNA    linear   ROD 26-SEP-2023
DEFINITION  Mus musculus nucleolar protein family 6 (RNA-associated) (Nol6),
            mRNA.
ACCESSION   NM_139236
VERSION     NM_139236.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4522)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4522)
  AUTHORS   Lu S, Borst DE and Horowits R.
  TITLE     Expression and alternative splicing of N-RAP during mouse skeletal
            muscle development
  JOURNAL   Cell Motil Cytoskeleton 65 (12), 945-954 (2008)
   PUBMED   18792955
  REMARK    GeneRIF: N-RAP-s is the predominant spliced form of N-RAP present
            throughout skeletal muscle development.
REFERENCE   3  (bases 1 to 4522)
  AUTHORS   Lu S and Horowits R.
  TITLE     Role of nonmuscle myosin IIB and N-RAP in cell spreading and
            myofibril assembly in primary mouse cardiomyocytes
  JOURNAL   Cell Motil Cytoskeleton 65 (9), 747-761 (2008)
   PUBMED   18615632
  REMARK    GeneRIF: The results show that NMHC IIB knockdown led to decreased
            N-RAP levels through proteasome-mediated degradation.
REFERENCE   4  (bases 1 to 4522)
  AUTHORS   Lu S, Carroll SL, Herrera AH, Ozanne B and Horowits R.
  TITLE     New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected
            by yeast two-hybrid screening: implications for myofibril assembly
  JOURNAL   J Cell Sci 116 (Pt 11), 2169-2178 (2003)
   PUBMED   12692149
  REMARK    GeneRIF: three new N-RAP binding partners: alpha-actinin,
            filamin-2, and Krp1 (also called sarcosin) in myofibril assembly
REFERENCE   5  (bases 1 to 4522)
  AUTHORS   Utama B, Kennedy D, Ru K and Mattick JS.
  TITLE     Isolation and characterization of a new nucleolar protein, Nrap,
            that is conserved from yeast to humans
  JOURNAL   Genes Cells 7 (2), 115-132 (2002)
   PUBMED   11895476
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN459855.1 and BC059820.1.
            
            [WARNING] On Jan 12, 2024 this sequence was replaced by
            NM_139236.4.
            
            On Mar 23, 2007 this sequence version replaced NM_139236.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059820.1, AK155818.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                CN459855.1         1-82
            83-4522             BC059820.1         1-4440
FEATURES             Location/Qualifiers
     source          1..4522
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 20.98 cM"
     gene            1..4522
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /note="nucleolar protein family 6 (RNA-associated)"
                     /db_xref="GeneID:230082"
                     /db_xref="MGI:MGI:2140151"
     exon            1..181
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..3553
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /codon_start=1
                     /product="nucleolar protein 6"
                     /protein_id="NP_631982.2"
                     /db_xref="CCDS:CCDS38715.1"
                     /db_xref="GeneID:230082"
                     /db_xref="MGI:MGI:2140151"
                     /translation="MPSAGERPAVKMGPAPAGEQHRRATEDPEVMELAFEGMDKEKAP
                     SRKRARTEPPAEGLLQPVNLSREELYKEPTNEELNRLRETEILFHSTLLRLQVEELLK
                     EVRLSEKKKERIDNFLKEVTKRIQKVPPVPEAELTDQSWLPAGVRVPLHQVPYAVKGS
                     FRFRPPSQITVVGSYLLDTCMRPDINVDVAVTMPREILQDKDGLNQRYFRKRALYLAH
                     LAYHLAQDPLFSSVRFSYMSGCHLKPSLLLRPHGKDERLVTVRLLPCPPLDFFRPCRL
                     LPTKNNVRSAWYRGQSCPDYEPPTPHYNTWILQDVALETHMHLLASVLGSAQGLKDGV
                     ALLKVWLRQRELDKGLGGFNGFIISMLVAFLVSKRKIHTTMSGYQVLRSVLQFLATTD
                     LTINGISFSLSSDPSLPTLAEFHQLFAVVFVDPSGRLNLCADVTASTYNQVQYEAELS
                     MALLDSKADDGFQLLLMTPKPMIQAFDHVVHLHPLSRLQASCHQLKLWPELQDNGGDY
                     VSAALGPLTNILVQGLGCRLHLLAHSRPPVPEWSINQDPPKHKDAGTLTLGFLFRPEG
                     LTSVIDLGPEADKPEAADFRQFWGTRSELRRFQDGAIREAVVWEAESLFEKRLIPHQV
                     VTHLLALHADIPDTCIQYVGGFLDALIQNPKEISSTGEEALALAVRCYDDLSRLLWGL
                     EGLPLTVSAVQGAHPVLRYTEVFPPAPVRPAYSFYNRLQELASLLPRPDKPCPAYVEP
                     MTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAEVLTQEHRLQCCATATHTDVLKDGFV
                     FRIRVAYQREPQILKEVRSPEGMVSLRDTPASLRLERDTKLLPLLTSALHGLQQQYPA
                     YSGVARLAKRWVRAQLLGEGFTDESLDLLAASLFLHPEPFTPPSVPQVGFLRFLYLVS
                     TFDWKNNPLIVNLNGELTAEEQVGIRSSFLAARTQLPVMVIITPQDRRSSVWTQDGPS
                     AQILQQLVSLAAEALPILEKQLMDPRGPGDIRTVFRPPFDMYDVLIHLTPRHIPRHRQ
                     AVDPPVASFCRGLLAEPGPSSLMPVLGYDPPQLYLAQLREAFEDLALFFYDQHGGEVI
                     GVLWKPSSFQPQPFKASSIKGRMVVSQGGELVMLPNIEAILEDFAVLGEGLVQAVEAR
                     SERWTV"
     exon            182..382
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            383..499
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            500..679
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            680..848
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            849..983
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1138
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1259
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1318
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1420
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1536
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1714
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1715..1837
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..1986
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2062
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2203
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..2321
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..2476
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2640
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2641..2793
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2794..2891
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..3016
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3106
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3301
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            3302..3403
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
     exon            3404..4483
                     /gene="Nol6"
                     /gene_synonym="Nrap"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggaactgca gtgggtgggg cctggggcaa gggtttgagc cctggagttg gcgtttcggc
       61 ccacgtggga agctacgggg tagatccggc ttggatgcca agtgctggag agagacctgc
      121 tgtgaagatg ggaccggccc ccgccggaga gcagcaccga cgagcaactg aggacccaga
      181 ggtgatggaa cttgccttcg aaggcatgga caaagagaag gcaccctcaa gaaagcgtgc
      241 aagaacagag ccacctgcag aaggcctcct gcagccagtg aacctcagtc gggaggagct
      301 gtacaaggag cctacaaatg aggagctaaa tcgcctccgt gagaccgaga tcttgttcca
      361 ctccaccttg cttcgtttac aagtggagga gttactaaag gaagtcagac tgtcagagaa
      421 gaagaaagag aggattgata atttcctgaa ggaggttacc aagcggatcc agaaagtgcc
      481 tccagtccct gaggctgagc tcactgacca gtcatggctc ccagctgggg tccgagtgcc
      541 cctccaccaa gtgccctatg ccgtgaaggg ctccttccgc ttccggcctc catcccagat
      601 cactgttgtg ggtagctacc ttctggatac ttgtatgcga ccagatatca atgtggacgt
      661 ggcagtgacc atgcccaggg aaatcttaca ggacaaagac gggctgaacc agcgttactt
      721 ccgcaagcga gccctttacc tggcccactt agcttaccac ctggcccagg atcccctctt
      781 cagcagcgta cgcttctctt acatgagtgg atgccacctg aagccctcgc tgctgctgcg
      841 gccacatggg aaggatgagc gcctagttac tgtgcgcctg cttccctgcc ctcccttgga
      901 cttcttccgt ccctgccgct tgctgccaac taagaacaat gtgcgctctg cctggtaccg
      961 agggcagagc tgtccggatt acgagccgcc taccccccac tataacacct ggatcctgca
     1021 ggatgtagct ctggagaccc acatgcactt gctggcaagt gtgctgggct ctgcccaggg
     1081 cctgaaggat ggcgtggcac ttctgaaggt ttggctgagg cagcgggaac tggacaaggg
     1141 cctgggtgga tttaacggat tcatcatctc catgctggtt gccttcctgg tatctaaacg
     1201 aaagatccat accaccatga gcggctacca ggtcctgaga agtgtcctgc agtttctggc
     1261 cactaccgat ctgacaatca atggaatcag tttctctctc agctcagatc cctccttgcc
     1321 caccctggct gaattccacc agcttttcgc ggttgtgttt gtggacccat caggccgcct
     1381 caacctctgt gccgatgtta cagcttccac ttacaaccag gtgcagtacg aggcagaact
     1441 gtctatggcg ttgctggaca gcaaagctga cgatggattt cagctgctgt tgatgactcc
     1501 caaacccatg atccaggctt ttgaccacgt tgtccatctc catccactga gtcgcctgca
     1561 ggcatcctgt caccagctaa agctttggcc agagctgcag gataacggag gggactacgt
     1621 ttcagccgct ctgggcccac taaccaacat tttggtgcag ggtctggggt gccggctgca
     1681 tctgctggct cactctcggc ccccagtccc agagtggagt atcaaccaag atcccccgaa
     1741 gcacaaggac gctgggaccc tgaccctggg atttctcttc cggcccgagg gactgaccag
     1801 tgttattgat cttggcccag aggctgacaa gcctgaggct gctgatttcc gtcagttctg
     1861 ggggacccgc tcagagctca ggcgtttcca ggacggagcc atccgggaag ctgtggtctg
     1921 ggaggcagaa tctttgtttg agaagcgtct tattcctcat caggtggtca cccacctctt
     1981 agcactccat gctgacatcc cagacacctg tatccagtat gtgggtggct tccttgatgc
     2041 attgatccaa aaccccaaag agatctccag cacgggtgag gaggccttgg cgttggctgt
     2101 gcgttgctat gatgacctca gccgcctgct ctgggggctg gagggtctcc cacttactgt
     2161 gtctgccgtt cagggggctc acccagtgct gcgctacaca gaggttttcc ctccagctcc
     2221 agtccgtcct gcctactcct tctataaccg cctccaagag ctggcctcac tgttgccccg
     2281 gccggataag ccctgcccag cctatgtgga gcctatgact gtggtttgtc acctggaggg
     2341 cagcgggcag tggcctcagg atgcagaagc ggtgcagcgg gtccgagccg ccttccagct
     2401 gcgcctggcg gaggtgctga cccaggagca tagactacag tgctgcgcca ctgccacaca
     2461 cacggatgtc ctcaaggatg ggttcgtgtt taggattcga gtggcctatc agcgggagcc
     2521 acagatcctg aaagaggtgc ggagccccga gggcatggtc tccctgagag acacacctgc
     2581 ctccctccgc cttgagagag acaccaagct gttgcctctg ctcaccagtg ccctgcatgg
     2641 actccagcag cagtacccag cctactcggg ggtggctcgc ctggccaagc ggtgggtgcg
     2701 tgcccagctt ctgggtgagg gcttcactga cgagagcctg gatctgctgg ccgcttcact
     2761 cttcctgcac cctgagccct tcacccctcc cagcgtccca caggttggct ttcttcggtt
     2821 cctttacttg gtatctacct ttgattggaa gaacaaccct ctcattgtca acctcaacgg
     2881 tgagctgact gctgaggaac aggtggggat tcgaagtagt ttcctggcag ctcgaacaca
     2941 actcccagtc atggtcatca ttacccccca ggaccgcaga agctctgtgt ggacacagga
     3001 tggaccctca gcccagatcc ttcagcagct cgtgagcctg gcggctgaag ccctccctat
     3061 cctagagaag cagctgatgg atccccgggg gcctggggac atcaggaccg tgttccggcc
     3121 acccttcgac atgtatgatg tgctgatcca cctgactccc cgccacattc cccggcaccg
     3181 ccaagctgta gaccctccag ttgcttcctt ctgccgtggt ctgctcgctg agccagggcc
     3241 ttcgtctctg atgcctgtcc tgggctatga cccccctcag ctctatctgg cacagctccg
     3301 ggaggccttt gaagatctgg ctctcttctt ctatgaccag catggtggag aggtgattgg
     3361 tgtcctctgg aagcccagca gcttccagcc ccagcccttt aaggcctcca gcataaaggg
     3421 acgcatggtg gtgtctcaag gtggggagct tgtgatgttg cccaacatag aagcaatctt
     3481 ggaggacttt gctgtgctgg gtgaaggcct ggtacaggct gtagaggccc gaagtgagag
     3541 gtggactgtg tgattctcgc cttgggacaa gtgttggatc tgtgcagcag caggtcagcg
     3601 gcatagccac tctcagtgca gatggacgcc tgatgaacca ctgaatcccc catccccaga
     3661 gaaagccccg tgagattctt ctgatgtttc agctctgggg caggggccat ggtgtcctgt
     3721 gtcccctaca cctgaccacc ccaattccca gaggaggaga cagagccagc tcagagagaa
     3781 ctgaatccac gagatccatt tgcctatcca tcttgagtca gcctgaactc ttgttcattt
     3841 ttgttttctc tccatcttca tcttcccgct ggcaggacgg atgtgtccag atgtcagcgt
     3901 gcctttccct gttgctgctt ctggccttta gattgtggcc cttcctgggg gtcagggcac
     3961 cagcactgag cagtgggagg gagctgtgtg tgtatgaatg gaacccattc agtaggcaca
     4021 gtgccctgag ggtaggaaca gtgggaaaag atacagacca ggcagggctg gctggagttg
     4081 aggggatccc ggtccaagag agagagagcg ctgggcgctg cagcctggcc tctctgggtc
     4141 ctgccccctc cttgctgctg cctatcatta cccattactg tgccatacgc ctgctcttgg
     4201 aactctgagg taggcaggat gcttcctctc agcctgatcc acatcccctt ctggcagcca
     4261 ctccctgctt ttctccccta atcctgactg tttttttttt tagactcagc tcaaatagca
     4321 ccccacctag tccctgccct cacccccacc cctctctccc ttctgtgaac tgtgaatgcg
     4381 attattcctt gtcgagttca cttggcaggc atgcatacca gtatgcacct tctattgtcc
     4441 tgaactctga tttaaaatta aattgcttaa gtctttctgg gtaaaaaaaa aaaaaaaaaa
     4501 aaaaaaaaaa aaaaaaaaaa aa
//
