LOCUS       NM_001347509            5339 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleolar protein 4 (Nol4), transcript variant 3,
            mRNA.
ACCESSION   NM_001347509 XM_006525997
VERSION     NM_001347509.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5339)
  AUTHORS   Toor,S.M., Wani,S. and Albagha,O.M.E.
  TITLE     Comprehensive Transcriptomic Profiling of Murine Osteoclast
            Differentiation Reveals Novel Differentially Expressed Genes and
            LncRNAs
  JOURNAL   Front Genet 12, 781272 (2021)
   PUBMED   34868271
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5339)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5339)
  AUTHORS   Takayanagi-Kiya,S., Misawa-Hojo,K., Kiya,T., Kunieda,T. and Kubo,T.
  TITLE     Splicing variants of NOL4 differentially regulate the transcription
            activity of Mlr1 and Mlr2 in cultured cells
  JOURNAL   Zoolog Sci 31 (11), 735-740 (2014)
   PUBMED   25366156
  REMARK    GeneRIF: These findings suggest that transactivation activities of
            Mlr1 and Mlr2 are differentially regulated by splicing variants of
            NOL4, which are expressed in a tissue-selective manner.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102361.13, AC131338.4 and AC103368.7.
            
            On Nov 30, 2016 this sequence version replaced XM_006525997.1.
            
            Transcript Variant: This variant (3) encodes the longest isoform
            (3).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.7693.1,
                                           SRR1660821.14254.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1903              AC102361.13        136323-138225
            1904-2053           AC131338.4         144044-144193       c
            2054-2165           AC131338.4         113729-113840       c
            2166-2278           AC131338.4         112698-112810       c
            2279-2411           AC131338.4         104465-104597       c
            2412-2695           AC131338.4         15170-15453         c
            2696-2875           AC103368.7         117978-118157       c
            2876-3067           AC103368.7         117041-117232       c
            3068-3181           AC103368.7         99224-99337         c
            3182-3359           AC103368.7         66276-66453         c
            3360-5339           AC103368.7         40452-42431         c
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 11.96 cM"
     gene            1..5339
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /note="nucleolar protein 4"
                     /db_xref="GeneID:319211"
                     /db_xref="MGI:MGI:2441684"
     exon            1..1903
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..2053
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2165
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2278
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2411
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2695
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2696..2875
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..3067
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3181
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            3182..3359
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     exon            3360..5339
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5296..5301
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /note="hexamer: AATAAA"
     regulatory      5317..5322
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /note="hexamer: AAGAAA"
     polyA_site      5322
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
                     /note="major polyA site"
     polyA_site      5334
                     /gene="Nol4"
                     /gene_synonym="1700013J13Rik; 4930568N03Rik; Gm1262"
ORIGIN      
        1 tgggggtgag gggagaggcg agaggttcag tgtgtggagc tgctcgcgca gcgcccgggc
       61 tgtcagtccg ggctggggcc gccccgagaa tcttccagga gaagcgcacc cccgcgcccc
      121 gcacaccctc gctcgaccac acacacgcac aagctcagcc tggccgcgcg ggagccactg
      181 agcagccaga gagctccggg accgagccgc gttcccattg gggctttcgc cggggagacc
      241 gcagcgagcc tccctggtgg gctcggacca ctcaggaacg cggcgagggt ccggccatcc
      301 ggctggctga gccgatccat gcgacccgcg ctggcctcgg cagggagtgc agtaaagagg
      361 agcggctgca gggagcagga ctggaactcc cctggttcca gcgccgccgc gacacacggg
      421 tggaaatcct aatggaggga tcgctgactt cctttgcttg ggaaaatcat caggagcaac
      481 tccgatttgg ctcctctgag catcggaggg gggtccatga cgtggcacgg gggaaataga
      541 caaccgaaac ctcccgtgtg aactgcaaac tataacctag ggagggagaa gaactgtttt
      601 ctgcatttta atttcacgca aaaaggttca agtgtctgtg cggtaaactt atttccatgt
      661 cttgtaccca ctccagcaga acccagaggg tcctatcttg gggatagcat cattccgaag
      721 agccccagcc agcggcctgt cttcctgttc ccacattgcc cggactgcat ccctgtttgg
      781 ggtactccat ctatcctata gagctatggt caggtatcta tgaatactgg gcgaatttct
      841 gaaacccaac tcttgcaacc taccttcgtg gctggaattt aacctaatac acctgaagaa
      901 atgatatttt gagtcgtttt taggatgcct tctttaaaat tcatgtaaaa caggatctga
      961 taggcttatc aacatgacag gtaagaactt tctggctctc tagttctgtc gcagaggagg
     1021 cccaggttaa gcaggagaga gagagagaga gagagtgaga gatacagtcc agggacccgt
     1081 gtgcccactg aggctcttca gcagaaggct gcttttgcta gaggcgcagc cctggctcct
     1141 ggacggacca tccgctgggg aagcttctgg ggcgcgagcc aggagactgc tttgcgctcc
     1201 acctgccttg ccctggacac agccctgggg gcgagacatc gagagaccac ctcaaatcaa
     1261 tattgggatt tttaataaac taaggaatgg gattttaatt attcagaaac ccagctccgc
     1321 tgggccagat gctgttggga tggtgctggt cacacagtgt taaagggacc gaccgctaag
     1381 agcactagaa aagcgtccga gacatccttt gcaattagga acgagccaga cttggtagca
     1441 cggggcattg attgctggtg cccatccgga ccctcctcct ctctccctga tcctgccccc
     1501 accccaccgg aggcagactc ccgcggttcg gccgggacct cgcgtccttg catcgtggtc
     1561 tgggcggcat atttcatgag accagggtga acaggtgcga agtgcgctgg gagcatccgg
     1621 cccacggcag cgagggaaca tggagagcga gcgcgacatg taccgccagt tccaggactg
     1681 gtgccttagg acttacgggg actcaggcaa gaccaagacg gtgacccgta agaaatatga
     1741 gcggattgtt cagcttctca acggctcaga gtcaagctcc accgacaatg ccaaatttaa
     1801 attctgggtc aaatcgaagg gtttccagct gggccagcct gatgaggtcc gtgggggagg
     1861 cggcggcgcc aagcaagtgc tcttcgtgcg ggtcaagacc acggatggcg taggagttga
     1921 tgagaagctg tctttacggc gagtggctgt ggttgaagat ttctttgaca tcatctattc
     1981 catgcatgtg gagacagggc cgaatggaga gcaaatccgg aaacacgctg ggcagaagag
     2041 aacttacaaa gcaatttcag agagctatgc cttcctacca agagaagcgg tgacacggtt
     2101 tctaatgagc tgttccgagt gccagaaaag aatgcacttg aacccagatg gaacggatca
     2161 caaagataat ggaaagcctc ctacactggt gaccagcatg atcgactaca acatgccaat
     2221 cacaatggcg tacatgaagc acatgaaact gcagcttctg aactcacagc aagatgagga
     2281 tgaaagctca atagaaagtg acgaatttga catgagtgat tcaacacgaa tgtcagccgt
     2341 gaactctgac cttagctcca acctggaaga aagaatgcaa agtccccaga ctgtccatgg
     2401 ccagcaagat gatgactctg ctgcagagag ctctaatggc aatgagactc tggggcacag
     2461 ctcagctgct tcagggggag cacatggcag ggagcccgag gactccagca gtgatggcaa
     2521 aaccgggctg gagcaggaag agcagccact gaacctgagt gacagcccca gctctgcaca
     2581 gctcacttca gagttcagga tagatgacca aggcagtgat gggaaaaaca agtataagaa
     2641 tcttctaatc tctgacctca agatggaacg agaagcgaga gaaaatggaa gcaagtctcc
     2701 agcacacagc tactccagct atgactctgg caaaaatgag agtgttgatc gaggtgcaga
     2761 ggatctgtca ctcaacaggg gagatgaaga tgaagatgaa catgatgagc atgaggattc
     2821 ggagaaggtg aacgagacag atggtgtgga agctgagagg ctgaaagctt tcaatatgtt
     2881 tgtcaggctg tttgtagatg aaaacttgga ccgaatggtc ccaatctcta agcagcccaa
     2941 agaaaagatc caggctatca ttgactcatg caggcgacaa ttccctgagt atcaagagcg
     3001 tgccagaaaa cgtatccgta cttacctcaa gtcctgcagg cggatgaaaa gaagtggttt
     3061 tgagatgtct cgacctattc cctcccacct tacttcagca gttgcagaga gtatcttggc
     3121 ttcagcctgt gaaagcgaga gtagaaatgc tgccaagagg atgcgtctgg ataaagcaca
     3181 ggatgaagct gctcctgctg acaaacagtg caagccggag gcagcccagg ccacctactc
     3241 aacagctact gttccaggct cccaggaggt attgtacatc aatggcaatg ggacctacag
     3301 ttaccatagt taccgagggc taggagggct gctaagcctg gatgacactt ctagtagcgg
     3361 acccacagat ctgagcatga agaggcagct ggcaactggc tcgggatcgt ccagcagctc
     3421 aacctccaga cctcagctca gtccgacgga aatcaatgcc gtgagacagc ttgtcgccgg
     3481 ttatcgagaa tcggctgcat ttttattgcg ttccgcagat gaactggaaa atctcatttt
     3541 acaacagaac tgaggcaaac gatgtctgta ctcactgggt tctaaatttg cagtttccac
     3601 taatgacact tgattttcca gcagagatac tcctaggctt gctgcacaac cttttgaggg
     3661 aagcatttcc atcatgccag gctgtccttg ctccataccc tggtgtgtta aggaacttca
     3721 caggaactct gaccttgaag tacttgagat gctcaaatgt gcccagcctg ttgctttatg
     3781 ttttagtgtg tcagcataaa tatcataagc agatttttaa aagcctggat attcttaatt
     3841 caaggataaa aatgaagaag cttgtggtat atatacatat atatataaag ctcaagatcc
     3901 aactgaaata ttagtggaat tttctactga ctcattggac tgaaagatga agtatctggg
     3961 gaaataaaaa gccaaatttc ttgttgctac aggatatgac aacaatgaaa aggatcttgt
     4021 attttaaaag aaaaaatgta atttttataa aaagaaaact tgtttttcat tcagaatggt
     4081 catttttact ttggtaactt tttcataggt cctaaaagaa aactgttttt tgagaaacta
     4141 ttgttaagta cccttcctgc atcccttttg ccttctcctc tttccaaatt ctttctacaa
     4201 aagaaaaata acaaccctca atgctggaaa accctttgcc tactttctgt aagtcaactc
     4261 atcaggaact acttccaaga gatgcctcca tttccagtct caaaacaccc acgccacacg
     4321 gcagcttacc acagaagttt tcatcccaga attttctaaa agttataaaa aagaccatgt
     4381 tgaaaacaaa acaaaaccca gccccttgcg cgtgctttcc tcagagctgc tcgcccctgg
     4441 ttgtgctacc aagcaaccct ccagagcagc gactgggtgt agatgactga atgttactga
     4501 ggttgcaagt gacaatctta aactttgcac tcttgtatgt atttctcatt tcttttggaa
     4561 atagtttcca ggaaaggctg ttatgtctcc tgctatgatt tgtatcattt aagcttctgt
     4621 tcttgtttta aattgagagc tctcagccga tcgagctgga tcttaacaac gaactctccc
     4681 ctcctgtctc ccaggctctg ccattttctc tatttctagt gttagacaca ctctgagtgg
     4741 tattttctgt gcactgaagc agcctatttt taaaatattt aaggagaagt accttagctc
     4801 atgcttgtac tagttccctt tctgttgttt agcttcggtt gaattacaaa ttctttgtgc
     4861 attcttgact ttgccttatt ttatgtaaaa tctctgtcat tcgggttttg acaatgagtt
     4921 gaaggcatta gtggcattcc ttactcctta catctagttt ttcaagtact gactgtgatt
     4981 gtgaccaggt aatgtgcact ttttcttgta actgtggaca ttgctatgct tttttcttct
     5041 agtgtttcta gaactattgt tccttacagt tacgtaaata aaaaaaaaca aaaacaaaca
     5101 aacaaacaaa caaaaacaaa aaaaatttgt gatactgttg gtgactataa tgtgaaaatc
     5161 ttattgaaat atgagtattt tggaaataca tagatgcaca aacatctttt aaaggtgtga
     5221 atttagagtt tgcttattta aggaaaattt aaaattttga gggctggtat aatttttctc
     5281 tgttttgttt ggtttaataa acagatttct gtgttaaaga aatgattctg aaaacttct
//
