LOCUS       NM_001416123            1959 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus nucleolar protein 12 (Nol12), transcript variant 4,
            mRNA.
ACCESSION   NM_001416123
VERSION     NM_001416123.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1959)
  AUTHORS   Rybkin,I.I., Kim,M.S., Bezprozvannaya,S., Qi,X., Richardson,J.A.,
            Plato,C.F., Hill,J.A., Bassel-Duby,R. and Olson,E.N.
  TITLE     Regulation of atrial natriuretic peptide secretion by a novel
            Ras-like protein
  JOURNAL   J Cell Biol 179 (3), 527-537 (2007)
   PUBMED   17984325
  REMARK    GeneRIF: RRP17 is a component of the cellular machinery involved in
            regulated secretion within the heart and potential mediator of the
            endocrine influence of the heart on other tissues
REFERENCE   2  (bases 1 to 1959)
  AUTHORS   Suzuki,S., Kanno,M., Fujiwara,T., Sugiyama,H., Yokoyama,A.,
            Takahashi,H. and Tanaka,J.
  TITLE     Molecular cloning and characterization of Nop25, a novel nucleolar
            RNA binding protein, highly conserved in vertebrate species
  JOURNAL   Exp Cell Res 312 (7), 1031-1041 (2006)
   PUBMED   16430885
REFERENCE   3  (bases 1 to 1959)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL831713.4 and AL589670.21.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.4657367.1,
                                           SRR7345562.4426236.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               AL831713.4         1613-1737           c
            126-231             AL831713.4         104-209             c
            232-280             AL589670.21        200736-200784       c
            281-423             AL589670.21        199968-200110       c
            424-524             AL589670.21        197752-197852       c
            525-1959            AL589670.21        196007-197441       c
FEATURES             Location/Qualifiers
     source          1..1959
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.7 cM"
     gene            1..1959
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /note="nucleolar protein 12"
                     /db_xref="GeneID:97961"
                     /db_xref="MGI:MGI:2146285"
     exon            1..125
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..756
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /note="isoform 4 is encoded by transcript variant 4; 25
                     kDa nucleolar protein; nucleolar protein of 25 kDa"
                     /codon_start=1
                     /product="nucleolar protein 12 isoform 4"
                     /protein_id="NP_001403052.1"
                     /db_xref="GeneID:97961"
                     /db_xref="MGI:MGI:2146285"
                     /translation="MGRNKKKKKRDGDDRRPRLVLNFDEEKRREYLTGFHKRKVERKK
                     AAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHP
                     NHTVTVTTISDLDLSGARLLGLPLPEQGDQDGSQEEEMSSLEKPTKALPRKSKDPLLS
                     QRYTARTQSEEGQEETPSAGTGLHQETSKCHTYQQDPAPPSDDWKSQAQRGVSPQTWG
                     SQLESLAVPVTQLHRGLPAA"
     exon            126..231
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     exon            232..280
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     exon            281..423
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     exon            424..524
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     exon            525..1959
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      913
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /note="major polyA site"
     regulatory      1940..1945
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nol12"
                     /gene_synonym="Nop25"
                     /note="hexamer: AATAAA"
     polyA_site      1959
                     /gene="Nol12"
                     /gene_synonym="Nop25"
ORIGIN      
        1 aaagtcagaa gcggccacgc tgccggaagc ttcactgcaa tgggccgcaa caagaagaag
       61 aagaaaagag atggagacga ccggcggccc cggctcgttc tcaactttga tgaagagaag
      121 cggcgggagt acctgacagg cttccacaag cggaaggtag agcgcaagaa ggcagccatt
      181 gaagagataa agcagcggct taagcaagag cagaagaaac ttcgggaaga gcgccaccag
      241 gagtacctga agatgctggc agaaagagag gaagcactgg aggaggcaga tgagctggag
      301 cggctagtga cagcgaagac agagtcggtg cagtatgacc accccaatca cacagtcact
      361 gtgaccacca tcagtgacct ggacctctca ggggcccggc tgctaggtct gcccctgcct
      421 gagcaagggg accaggatgg gtcccaggaa gaggagatgt catccctgga aaagccaaca
      481 aaagccttgc ccaggaagtc caaagatccc ctgctctctc agcgctacac tgcacgcaca
      541 cagtcggaag aaggtcaaga ggaaacaccc tcggcgggca caggactcca ccaagaaacc
      601 tccaagtgcc acacgtacca gcaagaccca gcgccgccgt cggatgactg gaaaagccag
      661 gcacaacggg gagtgagccc tcaaacctgg gggtcccagc ttgagtcctt ggctgtccct
      721 gtaacccagc tacaccgagg gttacctgca gcctaagcct gaaaatcagg actttgccat
      781 ccagggtcat ccttgctttg aacccagaag gaacggactt ctgagagccc gggttcccgg
      841 agcctgcaga accgtgctgg ggctcgttca caagtgtaca tccacctggg actgaagaga
      901 agtgtgaaac tcctccagtc tgtgcttgtg ctttgtcctg gcttggatcc catgcaccaa
      961 aggctgacct ctggggtggt gagaatggtc aggggtccat ctacctccag gttttcctga
     1021 aggtattaca aggtcatatc atatctgggc ccgctcatcc tagctgaaga ccagaatgta
     1081 gaatccagag ctgtggccag ctttggtggt atatggtaaa accacaccaa agaggctgag
     1141 acaggagact caattcaagg tcatccgtct tcagctacat agggagtttc aggctggtgg
     1201 gctgtcagga gatagctgaa gacttgagtg ccagcatcag aaggccacac tcagggacgg
     1261 aaagcttatc tccgggcctt tcctgggagc tggcttggcc tgacctcagc ccttctcccc
     1321 attccctgcc ctctgctcca agagcagtga ctacctgata cctgtctgag atgggcctgc
     1381 ctctcctgga ggttctagtg ttcaacccag tgaaggggac ctgggcctca ctgtctagac
     1441 cactgatcag gacagtaagc caggaaatag agggatttgg tacccatgtg agcctcaagc
     1501 agtgctgttc tactgggtgt ttccctttat gaatctccag ggctaccctg aggctggagt
     1561 gggtattaca ggatgctctg cacaacacta ggctcacaca cctcaccgct cacagcatgt
     1621 ccctgtcccc tcagtggaga tttctgcctc tggagacatg aagtcatttc cagtgtacac
     1681 aagaggacac aggagaccct ccatacacac atacatagga gaccacaaac acaccctaca
     1741 cactgtttct ctaatcacga actccttccc tgtctcccca gctgcccaga gtcgcatctg
     1801 tttggacttc aggagcagca gcgaggggag ctgccatggt ggcacacact agtcctagca
     1861 cttagaagcc tggggggtgt gggggagggt atgggggact tttgggatag cattggaaat
     1921 gtaattgagg aaaagacata ataaaaaaaa tagagccta
//
