LOCUS       NM_001008421            3004 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus nucleolar protein 10 (Nol10), mRNA.
ACCESSION   NM_001008421 XM_126825
VERSION     NM_001008421.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3004)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3004)
  AUTHORS   Ghazalpour,A., Doss,S., Zhang,B., Wang,S., Plaisier,C.,
            Castellanos,R., Brozell,A., Schadt,E.E., Drake,T.A., Lusis,A.J. and
            Horvath,S.
  TITLE     Integrating genetic and network analysis to characterize genes
            related to mouse weight
  JOURNAL   PLoS Genet 2 (8), e130 (2006)
   PUBMED   16934000
REFERENCE   3  (bases 1 to 3004)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086676.1.
            
            On Dec 16, 2004 this sequence version replaced XM_126825.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086676.1, AK160864.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3004
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 8.07 cM"
     gene            1..3004
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /note="nucleolar protein 10"
                     /db_xref="GeneID:217431"
                     /db_xref="MGI:MGI:2684913"
     exon            1..127
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..2125
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /codon_start=1
                     /product="nucleolar protein 10"
                     /protein_id="NP_001008421.1"
                     /db_xref="CCDS:CCDS25828.1"
                     /db_xref="GeneID:217431"
                     /db_xref="MGI:MGI:2684913"
                     /translation="MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKNVDVRRRIE
                     LIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEI
                     LSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYR
                     LNLEQGRYLNPLQTDAAENNVCDINAVHGLFATGTIEGRVECWDPRVRKRVGVLDCAL
                     NSVTADSEINSLPTISALKFNGALSMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIK
                     SVHFQDSLDLVLSADSRIVKMWNKDSGKIFTSLEPEHDLNDVCLYPSSGMLLTANESP
                     KMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGS
                     PFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVN
                     KELALKLIEEEEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP
                     LVSRISEKRKKQLRLLEQQELKDEEEEEPEGKPSDAESSESSDDEKGWVEEVRKQRRL
                     LQQEERVKRQEQLKEDQQTVLKPQFYEIKAGEEFRSFKESATKQRLMNKTLEDRLKLE
                     AKHGTLNVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKNLRRSASHLRSRPRR
                     GRPFH"
     exon            128..173
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            174..272
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            273..350
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            351..388
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            389..525
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            526..591
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            592..652
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            653..738
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            739..817
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            818..967
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1034
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1087
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1214
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1294
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1393
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1483
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1654
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1902
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2005
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2986
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2965..2970
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /note="hexamer: AATAAA"
     polyA_site      2986
                     /gene="Nol10"
                     /gene_synonym="Gm67"
                     /note="major polyA site"
ORIGIN      
        1 ggtattcggg tgggccggcg ttctgtgact gcgtgccggg ctccggctgc tccgcgctgc
       61 gatgcaggtc tccagcctca acgaagtgaa gatttacagc ctcagctgcg gcaagtctct
      121 tcccgagtgg ctttctgaca ggaagaagag agcactgcag aagaagaatg tcgatgttcg
      181 taggagaatt gaacttattc aggacttcga aatgcctact gtgtgtacta ctatcaaggt
      241 gtcaaaagat ggacagtata ttttagcaac tggaacatat aagcctcggg tccggtgtta
      301 tgacacatat cagttatccc tgaagtttga aaggtgcttg gattctgaag ttgtcacctt
      361 tgagatttta tcagatgact attcaaagat tgtcttctta cataatgaca gatatattga
      421 atttcactca caatcaggct tttactacaa aaccagaatt cccaagttcg gccgagactt
      481 ctcttaccac tatccatcct gtgacttgta ctttgtaggt gcaagctctg aagtttatag
      541 attaaactta gaacaagggc ggtacctgaa tcctctccag acggacgccg cggagaacaa
      601 tgtttgtgac ataaatgcag tgcatggctt gttcgccaca ggaacaatag agggtcgagt
      661 ggaatgctgg gatccaagag taagaaaaag ggttggcgtg ttagactgtg cattaaatag
      721 tgtcacagca gattcagaga taaacagctt acccaccatc tctgcattga agtttaatgg
      781 agccttgagc atggcagttg gaacatccac agggcaggtg ttgttatatg atcttcgctc
      841 ggataagccg ttgctagtta aggatcacca gtatgggctg ccgattaagt cagttcattt
      901 ccaggattcc ctagatttgg ttttgtctgc agactctaga attgtcaaaa tgtggaacaa
      961 ggactccggg aaaatattta cttcgttgga gccagaacat gatcttaatg atgtttgcct
     1021 ctatcccagc tcaggaatgc ttcttactgc caatgaatcc cccaagatgg gcatttacta
     1081 cattccggtt ttgggtcctg ctcccaggtg gtgttccttc ctggacaact tgacagaaga
     1141 gttagaagag aatccagaga gcacagtgta tgatgattac aaatttgtca ccaagaaaga
     1201 ccttgaaaat ttagggctca cacatctcat tggatcacct ttcctccgag catatatgca
     1261 tgggtttttc atggatatca gactctacca caaggtgaaa ttgatggtca atccatttgc
     1321 ttatgaagaa tataggaaag ataaaattcg acagaagata gaagaaacac gtgcacagag
     1381 agtccaatta aagaaactgc caaaagttaa caaagaactg gcacttaaat taattgaaga
     1441 ggaagaggag aaacaaaagt ctacgctgaa aaagaaagtt aagagcctcc ctaatatcct
     1501 cacggatgat cgatttaaag ttatgtttga gaatcccgac ttccaggtgg acgaggagag
     1561 tgaagagttc aggcttctca accccctcgt ctcgaggatc agtgagaaga ggaagaagca
     1621 gctgaggctc ttggagcagc aggagctcaa ggatgaagag gaggaagaac cggaaggaaa
     1681 acccagtgat gcagaaagtt cagagagctc agatgatgag aaaggttggg ttgaagaagt
     1741 caggaagcag cgcagactcc ttcagcagga agaaagagtg aagcggcagg agcaactgaa
     1801 ggaggaccag cagacagtcc tgaagcccca gttctacgag atcaaagcag gcgaagagtt
     1861 caggagcttc aaagagtctg ccaccaagca gagactaatg aacaaaactc tggaagatcg
     1921 tttgaaactt gaagcaaaac atgggacatt gaatgtatcg gacaccactg ttggcagcaa
     1981 gcagttgaca tttactctca agaggtctga acagcaaaag aagcaacagg aggctgaaaa
     2041 actgcatcgt caggaaagga aaaatctgcg caggtcggcc agccacctga ggtccagacc
     2101 cagaagaggc cggccctttc actgaccaaa gaaatgtgcc cacgagcaac tagacgctgt
     2161 gcttctcccc atggattctc acaagggcat cacacccagg ctccgtgtag atgtgtgtgc
     2221 atggtgctgg tggtctgact ggcccactac ccacctggag aagtccctgg ccctgggtgc
     2281 tttttccaag tggctgcccc tttctctctc cccctccccc gcccccctta aatcttgtct
     2341 tctcccctgc tgatgatcag gcatcatttc agatattgga aaggcctcca tgaagtgaaa
     2401 agttcaccct ctactggaaa caggacatta tcatgctgta agaatggctt gggttagccc
     2461 agccgtggtg gcgcacgcct ttgatcccag cacttgggag gcagaggcag gcggatttct
     2521 gagttcgagg ccagcctggt ctacagagtg agttccagga cagccagagc tacacagaga
     2581 aaacctgtct ggaacccccc ccccccaaaa aaaagaatgg tttggggttt tttgttttgt
     2641 tttgttttgt ttttttgtca tttgtttatt tgagacttga gtcagggttt ctccgtgtag
     2701 ctctgggtgt cctggaattc aatctgtggc cttgaactca tagagatcca cttgcctctg
     2761 cctcctgagt gctgaagtta aagggatgca ccaccaggcc cagccagagt gtctgtcccc
     2821 actgtcttct gcccctcagg actgagtcac atgatgactg ctgagtggcc ctgtttatgt
     2881 gcatgagtat gttggcaggc tgactggctt gcttatattc ctttgtatag tttttaagct
     2941 atttttatat caagggtata aattaataaa taataagtga acgctaaaaa aaaaaaaaaa
     3001 aaaa
//
