LOCUS       NM_008711               1922 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus noggin (Nog), mRNA.
ACCESSION   NM_008711
VERSION     NM_008711.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Lehr,S., Bruckner,D.B., Minchington,T.G., Greunz-Schindler,M.,
            Merrin,J., Hannezo,E. and Kicheva,A.
  TITLE     Self-organized pattern formation in the developing mouse neural
            tube by a temporal relay of BMP signaling
  JOURNAL   Dev Cell (2024) In press
   PUBMED   39603235
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 1922)
  AUTHORS   Sorsby,M., Almardini,S., Alayyat,A., Hughes,A., Venkat,S.,
            Rahman,M., Baker,J., Rana,R., Rosen,V. and Liu,E.S.
  TITLE     The role of GDF5 in regulating enthesopathy development in the Hyp
            mouse model of XLH
  JOURNAL   J Bone Miner Res 39 (8), 1162-1173 (2024)
   PUBMED   38836497
REFERENCE   3  (bases 1 to 1922)
  AUTHORS   Krammer,T., Stuart,H.T., Gromberg,E., Ishihara,K., Cislo,D.,
            Melchionda,M., Becerril Perez,F., Wang,J., Costantini,E., Lehr,S.,
            Arbanas,L., Hormann,A., Neumuller,R.A., Elvassore,N., Siggia,E.,
            Briscoe,J., Kicheva,A. and Tanaka,E.M.
  TITLE     Mouse neural tube organoids self-organize floorplate through
            BMP-mediated cluster competition
  JOURNAL   Dev Cell 59 (15), 1940-1953 (2024)
   PUBMED   38776925
REFERENCE   4  (bases 1 to 1922)
  AUTHORS   de Vries,M.E., Carpinelli,M.R., Fuller,J.N., Sutton,Y.,
            Partridge,D.D., Auden,A., Anderson,P.J., Jane,S.M. and Dworkin,S.
  TITLE     Grainyhead-like 2 interacts with noggin to regulate tissue fusion
            in mouse
  JOURNAL   Development 151 (5) (2024)
   PUBMED   38300806
  REMARK    GeneRIF: Grainyhead-like 2 interacts with noggin to regulate tissue
            fusion in mouse.
REFERENCE   5  (bases 1 to 1922)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   6  (bases 1 to 1922)
  AUTHORS   Puech,A., Saint-Jore,B., Funke,B., Gilbert,D.J., Sirotkin,H.,
            Copeland,N.G., Jenkins,N.A., Kucherlapati,R., Morrow,B. and
            Skoultchi,A.I.
  TITLE     Comparative mapping of the human 22q11 chromosomal region and the
            orthologous region in mice reveals complex changes in gene
            organization
  JOURNAL   Proc Natl Acad Sci U S A 94 (26), 14608-14613 (1997)
   PUBMED   9405660
REFERENCE   7  (bases 1 to 1922)
  AUTHORS   Yoshida,M., Suda,Y., Matsuo,I., Miyamoto,N., Takeda,N., Kuratani,S.
            and Aizawa,S.
  TITLE     Emx1 and Emx2 functions in development of dorsal telencephalon
  JOURNAL   Development 124 (1), 101-111 (1997)
   PUBMED   9006071
REFERENCE   8  (bases 1 to 1922)
  AUTHORS   Shimamura,K., Hartigan,D.J., Martinez,S., Puelles,L. and
            Rubenstein,J.L.
  TITLE     Longitudinal organization of the anterior neural plate and neural
            tube
  JOURNAL   Development 121 (12), 3923-3933 (1995)
   PUBMED   8575293
  REMARK    Review article
REFERENCE   9  (bases 1 to 1922)
  AUTHORS   Wijgerde,M., Grosveld,F. and Fraser,P.
  TITLE     Transcription complex stability and chromatin dynamics in vivo
  JOURNAL   Nature 377 (6546), 209-213 (1995)
   PUBMED   7675106
REFERENCE   10 (bases 1 to 1922)
  AUTHORS   Valenzuela,D.M., Economides,A.N., Rojas,E., Lamb,T.M., Nunez,L.,
            Jones,P., Lp,N.Y., Espinosa,R. 3rd, Brannan,C.I., Gilbert,D.J. et
            al.
  TITLE     Identification of mammalian noggin and its expression in the adult
            nervous system
  JOURNAL   J Neurosci 15 (9), 6077-6084 (1995)
   PUBMED   7666191
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK146488.1, BC132527.1 and CA752122.1.
            
            On Oct 12, 2007 this sequence version replaced NM_008711.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK146488.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-474               AK146488.1         2-475
            475-778             BC132527.1         1-304
            779-1698            AK146488.1         782-1701
            1699-1922           CA752122.1         355-578
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 54.34 cM"
     gene            1..1922
                     /gene="Nog"
                     /note="noggin"
                     /db_xref="GeneID:18121"
                     /db_xref="MGI:MGI:104327"
     exon            1..1922
                     /gene="Nog"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1899..1904
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nog"
                     /note="hexamer: ATTAAA"
     polyA_site      1922
                     /gene="Nog"
                     /note="major polyA site"
ORIGIN      
        1 agacaaaccg gtgccaacgt gcgcggacgc cgccgccgcc accgccgcca ccgccgctgg
       61 agtccgccgg gcagagccgg ctgcgctgcc cggagcaggc agagagaagt ggcccaggac
      121 ccgctctacc ggaggctccg cacagagaaa caagacgccg agcgaccgga ggaggaggag
      181 ggaaaaggct cgtccacgcg ccctgcgccg ccggcagccc gggagaacag cgaggagccg
      241 gcgcccccag cgccccacgg tcgcgctgga gtaatctcgg atgcccgacc gcggccgcct
      301 tcccaagtag agcggcgggg gggaattgcg accaactcgt gcgcgtcttc tgcgccgcgg
      361 cgggagccgg cgctgcgcga acggctctcc tcgcggctca tgctgcctgc cctgcgcctg
      421 ctcagcctcg ggtgagccac ctccggaggg accggggagc acggcagcgc cgcggactcg
      481 gcgtgctctc ctccggggac gcgggacgaa gaggcagccc cggggcgcgc gcgggaggca
      541 tggagcgctg ccccagcctg ggggtcaccc tctacgccct ggtggtggtc ctggggctgc
      601 gggcagcacc agccggcggc cagcactatc tacacatccg cccagcaccc agcgacaacc
      661 tgcccctggt ggacctcatc gaacatccag accctatctt tgaccctaag gagaaggatc
      721 tgaacgagac gctgctgcgc tcgctgctcg ggggccacta cgacccgggc tttatggcta
      781 cttcgccccc tgaggaccga cccggagggg gcgggggacc ggctggaggt gccgaggacc
      841 tggcggagct ggaccagctg ctgcggcagc ggccgtcggg ggccatgccg agcgagatca
      901 aagggctgga gttctccgag ggcttggccc aaggcaagaa acagcgcctg agcaagaagc
      961 tgaggaggaa gttacagatg tggctgtggt cacagacctt ctgcccggtg ctgtacgcgt
     1021 ggaatgacct aggcagccgc ttttggccac gctacgtgaa ggtgggcagc tgcttcagca
     1081 agcgctcctg ctctgtgccc gagggcatgg tgtgtaagcc atccaagtct gtgcacctca
     1141 cggtgctgcg gtggcgctgt cagcggcgcg ggggtcagcg ctgcggctgg attcccatcc
     1201 agtaccccat catttccgag tgtaagtgtt cctgctagaa ctcggggggg ccccctgccc
     1261 gcgcccagac acttgatgga tccccaccaa cgccccccct acccccacca cctccaacca
     1321 gtttcaccac cctctagcga gggttttcaa tgaacttttt ttcttcttgg ctacagagac
     1381 ctggctttct ggttcctgta atgcactgtt taactgtgta ggaatgtata tgtgtgtgta
     1441 tatacggtcc cagttttaat ttacttatta aaaggtcagt attatacgtc aaaagttacc
     1501 cggcttctac tgtattttaa aaaggcaagc aaaaggaaaa aagagcagag aaaagagaga
     1561 cttattctgg ttgttggtaa taatgttaac ctgctattta tatcccagta cccttcgcat
     1621 ggcgaagcag gggggaaaag ttattttttc ttaaaagtac aaagagaggg ggaacttttg
     1681 tagaaggact ttttttttaa aaaaaagcta ttttccattc ttcggaaagt gttttgattt
     1741 tccttagacc tcgaagaagt tatagagttc aatgttattt tacagttatt gtaaatatag
     1801 agaacaaatg gaatgactaa tcattgtaaa ttaagagtat ctgctattta ttctttataa
     1861 tatcccgtgt agtaaataag gaagaagtgc agaacaggat taaagaaaac cactaaaacc
     1921 ga
//
