LOCUS       NM_001048219            3349 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus NLR family, pyrin domain containing 9A (Nlrp9a),
            transcript variant 1, mRNA.
ACCESSION   NM_001048219
VERSION     NM_001048219.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3349)
  AUTHORS   Kanzaki,S., Tamura,S., Ito,T., Wakabayashi,M., Saito,K., Kato,S.,
            Ohta,Y., Sekita,Y. and Kimura,T.
  TITLE     Involvement of Nlrp9a/b/c in mouse preimplantation development
  JOURNAL   Reproduction 160 (2), 181-191 (2020)
   PUBMED   32413845
REFERENCE   2  (bases 1 to 3349)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 3349)
  AUTHORS   Dade,S., Callebaut,I., Paillisson,A., Bontoux,M., Dalbies-Tran,R.
            and Monget,P.
  TITLE     In silico identification and structural features of six new genes
            similar to MATER specifically expressed in the oocyte
  JOURNAL   Biochem Biophys Res Commun 324 (2), 547-553 (2004)
   PUBMED   15474461
REFERENCE   4  (bases 1 to 3349)
  AUTHORS   Hamatani,T., Falco,G., Carter,M.G., Akutsu,H., Stagg,C.A.,
            Sharov,A.A., Dudekula,D.B., VanBuren,V. and Ko,M.S.
  TITLE     Age-associated alteration of gene expression patterns in mouse
            oocytes
  JOURNAL   Hum Mol Genet 13 (19), 2263-2278 (2004)
   PUBMED   15317747
REFERENCE   5  (bases 1 to 3349)
  AUTHORS   Anderson,J.P., Mueller,J.L., Rosengren,S., Boyle,D.L., Schaner,P.,
            Cannon,S.B., Goodyear,C.S. and Hoffman,H.M.
  TITLE     Structural, expression, and evolutionary analysis of mouse CIAS1
  JOURNAL   Gene 338 (1), 25-34 (2004)
   PUBMED   15302403
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120367.8, AK139925.1, AY364009.1 and DV652646.1.
            
            On Nov 15, 2014 this sequence version replaced NM_001048219.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK139925.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                AC120367.8         94625-94667
            44-732              AK139925.1         2-690
            733-815             AY364009.1         607-689
            816-2368            AK139925.1         775-2327
            2369-2369           AC120367.8         124501-124501
            2370-2548           AK139925.1         2329-2507
            2549-2606           AC120367.8         127506-127563
            2607-2874           AK139925.1         2566-2833
            2875-2875           AC120367.8         130897-130897
            2876-3328           AK139925.1         2835-3287
            3329-3349           DV652646.1         560-580
FEATURES             Location/Qualifiers
     source          1..3349
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 15.08 cM"
     gene            1..3349
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /note="NLR family, pyrin domain containing 9A"
                     /db_xref="GeneID:233001"
                     /db_xref="MGI:MGI:2675292"
     exon            1..88
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            89..397
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..3141
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /note="isoform 1 is encoded by transcript variant 1;
                     NACHT, LRR and PYD domains-containing protein 9A"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 9A
                     isoform 1"
                     /protein_id="NP_001041684.1"
                     /db_xref="CCDS:CCDS39844.1"
                     /db_xref="GeneID:233001"
                     /db_xref="MGI:MGI:2675292"
                     /translation="MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTK
                     IKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKN
                     TFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLR
                     KAMLDWASRNLLQNRFQYVFYFSVFSLNNITELSLAELISSTLPESSETVDDILSDPK
                     RILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNAS
                     LSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPH
                     LCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLC
                     TLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAV
                     LFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGC
                     ISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTV
                     DISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLDQKLLAKHW
                     TTLCTFLCNLHVLDLDSCHFNEKAIEVLCNCLPLTSLVPLTGFKLHRLLCSFTTNFGD
                     GLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACG
                     IIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHL
                     YEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEIS
                     AVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLAL
                     VLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAV
                     EKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN"
     exon            398..1979
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2144
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2145..2309
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2477
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..2648
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2649..2819
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2990
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
     exon            2991..3336
                     /gene="Nlrp9a"
                     /gene_synonym="D7Ertd565e; Nalp-theta; Nalp9a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagaagctag catgacttct tagtcagtct tagtttttca cagtggccct tcaataagta
       61 ctagcccatg ggaccaggtc tggaatggat ttatcaacct ctagattctg aggtcactgt
      121 cccaagatga tggactcatc tgggtatggc ttgctgcagt atttgcaaaa gctcagtgat
      181 gaagagttcc agagatttaa agaacatctc aggaaagagc cagagaaatt taaacttaaa
      241 cctatctcct ggactaagat caaaaacact tccaaagaag acctggtaat gcaattgtac
      301 acacattatc caggaaaggc atgggatatg gtgttgagcc tgtttctaca ggtcaatcgg
      361 gaagacctct caaccatggc tcagacagaa aggagagata aacaaactaa atacaaagag
      421 tttatgaaga atacatttca gcacatatgg acaatggaga ccaacactta tatacctgat
      481 agaagctacc acgaatttat agaagtccag tacagagcat tgcaggacat atttgattgt
      541 gagtcagagc cagtcactgt agttgtatca ggttctagag gaggaggtaa aactactttc
      601 ttaagaaaag caatgttgga ttgggcatca agaaatttac tgcagaaccg atttcaatat
      661 gttttctact tctccgtctt ctcacttaac aatatcacag agttaagctt agctgagctt
      721 atctcaagta cgttgcctga atcttcagag acagtggatg atattttatc tgatccaaaa
      781 agaatcttgt ttatcctgga tggatttgat tacctgaaat ttgacttgga actcaggaca
      841 aacctgtgca atgactggag gaagaagctg ccaatacaaa ttgtcttgag tagtttgcta
      901 cagaaaataa tgctcccaga atgttctctg ctccttgaat tgggaaatgc aagtctttca
      961 aacattattc ctttgctgca atatccaagg gagataatta tgtcaggatt ctctgaacaa
     1021 actatagaaa tctactgtgt gtctttcttt aatacccaga caggtgtaga aatctttaag
     1081 aatttaaaga gcattaaacc attgttcaat ttatgccgct gtcctcatct atgctggatg
     1141 atctgtagta ctataaagtg gcagtatgag aggagagagg tagcaagtcg ttttggtcga
     1201 acattaggac tcctctacac aatatttatg gttagcgcat ttaaatcaac atatgccagg
     1261 aatccatcta aacagaacag ggcccgtata aggaccctat gcaccttggc tgtagaggga
     1321 atgtggaaac aggtatatgt gtttgactct gatgacctca ggaggaatgg gatatctgaa
     1381 tcagataaga aagtgtggct gagaatgaaa tttctccaga atcaaggtag caacattgta
     1441 ttttatcatt ctacactaca gtggtacttt gctgtgctgt tctattttct ccaatacaaa
     1501 gacacacgtc acccagttat tggaaacctc gctcaactcc taggagaaat ctatgctcat
     1561 aaacagaacc aatggttcca cacacggata ttattgtttg gaatggccac tgagcaagtt
     1621 aactccttgc ttgaaccatg ctttggctgt atatcatcca aggaggtaag acaggaaatc
     1681 atcagataca tcaaaagtct cagtcaacaa gaatgcaatg aaaaactggt ggtgcatccc
     1741 cagaatttgt ttttctgtat acttgacaac caggaggaaa gatttgtaag acaattgatg
     1801 gatcgatttg aagaaatgac tgttgatatt agtgatgttg atgatatgtc agcaactcca
     1861 tattgtctgc atagagcccc aaaagtgaaa aaccttcacc tgcatataca aaagagagtt
     1921 tttttagaaa tccatgatcc agaatatggt gacttagaac tctttaaact cgaccaaaaa
     1981 cttttagcca agcattggac tacgttatgc acttttctct gtaacttaca tgtgttggat
     2041 ctggacagct gtcatttcaa tgaaaaagcc atagaggttc tctgtaattg tttgcctcta
     2101 acttctttag tacctctgac tggttttaag ctccacagat tgttgtgttc cttcacgact
     2161 aactttggag atggtttatt attttgcaca tttcttcacc tacctcacct gaaatacatg
     2221 aacctgtatg gcactaatct ctctaatgat gcagttgaga ggctgtgctc agctctgaaa
     2281 ttttcaacat gtggagtgga ggagctgttg ttgggaaaat gtgacatatc aagtgaggct
     2341 tgtggcataa ttgcagcttc ccttatcaat tctgaggtga aacatctctc attggttgaa
     2401 aatcccttga agaacaaagg agtgatgtca ctgtgtgaaa tgctgaagga tccaagctgt
     2461 gtcctggaat cactgatgtt gtcttactgc tgtctcacat tcattgcctg tggacatctc
     2521 tatgaagctc ttttgagcaa tgaacacctc tctctgcttg atctggggtc aaatttcctg
     2581 gaagacactg gagtgaacct tctgtgtgaa gctttgaaag atccaaactg caccctcaag
     2641 gagttatggt tgcctggttg ctatttaact tcagaatgtt gtgaagagat ctcggctgtc
     2701 ctgacttgca atacaaatct aaagaccctg aaacttggca acaataacat acaagacact
     2761 ggtgtcaaac ggttatgtga agctctgtgt catcctaact gtgaaatgca gtgtcttggg
     2821 ttagacatgt gtgacttcac cagtgactgt tgtgaagacc tggccttggt tcttaccacc
     2881 tgcaacacat tgaagagctt aaaccttgac tggaatgcct ttgaccattc tgggctggag
     2941 atgctctgta aggccttgaa tcacaaagcc tgtaacctgg aggtgcttgg actggacaaa
     3001 tctttatttt ctgaggaatc acagacatta ctgcaagctg tggaaaagaa aaataaaaat
     3061 ctgaaagttt tgcattttcc ctggcttaaa gaggaactcg aaaagagggg tgttcgtctg
     3121 gtatggaaca gcaagaattg atctgtaaca aaggtttatc cttttttatg tttctcctat
     3181 ataccctgtc ccaagttgca caccatggta ctggtggctg tcgccagagc tgttcttcca
     3241 cattgttcca cccccacctt tctttatatc tcccctcacc actttgcaat gtttatacta
     3301 caagcacatt caataaacac taagcatgtg tgaaaaaaaa aaaaaaaaa
//
