LOCUS       NM_175290               3527 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus NLR family, pyrin domain containing 4F (Nlrp4f), mRNA.
ACCESSION   NM_175290
VERSION     NM_175290.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3527)
  AUTHORS   Zhang,W., Zhang,R., Wu,L., Zhu,C., Zhang,C., Xu,C., Zhao,S.,
            Liu,X., Guo,T., Lu,Y., Gao,Z., Yu,X., Li,L., Chen,Z.J., Qin,Y. and
            Jiao,X.
  TITLE     NLRP14 deficiency causes female infertility with oocyte maturation
            defects and early embryonic arrest by impairing cytoplasmic UHRF1
            abundance
  JOURNAL   Cell Rep 42 (12), 113531 (2023)
   PUBMED   38060382
REFERENCE   2  (bases 1 to 3527)
  AUTHORS   Qin,D., Gao,Z., Xiao,Y., Zhang,X., Ma,H., Yu,X., Nie,X., Fan,N.,
            Wang,X., Ouyang,Y., Sun,Q.Y., Yi,Z. and Li,L.
  TITLE     The subcortical maternal complex protein Nlrp4f is involved in
            cytoplasmic lattice formation and organelle distribution
  JOURNAL   Development 146 (20) (2019)
   PUBMED   31575650
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3527)
  AUTHORS   Madissoon,E., Tohonen,V., Vesterlund,L., Katayama,S., Unneberg,P.,
            Inzunza,J., Hovatta,O. and Kere,J.
  TITLE     Differences in gene expression between mouse and human for
            dynamically regulated genes in early embryo
  JOURNAL   PLoS One 9 (8), e102949 (2014)
   PUBMED   25089626
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3527)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   5  (bases 1 to 3527)
  AUTHORS   Joshi,S., Davies,H., Sims,L.P., Levy,S.E. and Dean,J.
  TITLE     Ovarian gene expression in the absence of FIGLA, an oocyte-specific
            transcription factor
  JOURNAL   BMC Dev Biol 7, 67 (2007)
   PUBMED   17567914
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3527)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   7  (bases 1 to 3527)
  AUTHORS   Dade,S., Callebaut,I., Paillisson,A., Bontoux,M., Dalbies-Tran,R.
            and Monget,P.
  TITLE     In silico identification and structural features of six new genes
            similar to MATER specifically expressed in the oocyte
  JOURNAL   Biochem Biophys Res Commun 324 (2), 547-553 (2004)
   PUBMED   15474461
REFERENCE   8  (bases 1 to 3527)
  AUTHORS   Hamatani,T., Falco,G., Carter,M.G., Akutsu,H., Stagg,C.A.,
            Sharov,A.A., Dudekula,D.B., VanBuren,V. and Ko,M.S.
  TITLE     Age-associated alteration of gene expression patterns in mouse
            oocytes
  JOURNAL   Hum Mol Genet 13 (19), 2263-2278 (2004)
   PUBMED   15317747
REFERENCE   9  (bases 1 to 3527)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK135866.1, DV656119.1, BC098479.1, AK049352.1 and CD541102.1.
            
            On Apr 5, 2007 this sequence version replaced NM_175290.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784643.1158587.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1266              AK135866.1         31-1296
            1267-1578           DV656119.1         295-606
            1579-2944           BC098479.1         1-1366
            2945-3519           AK049352.1         1348-1922
            3520-3527           CD541102.1         1-8                 c
FEATURES             Location/Qualifiers
     source          1..3527
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 34.45 cM"
     gene            1..3527
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /note="NLR family, pyrin domain containing 4F"
                     /db_xref="GeneID:97895"
                     /db_xref="MGI:MGI:2145528"
     exon            1..97
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            98..399
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..2939
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /note="NACHT, leucine rich repeat and PYD containing 4F;
                     NALP, kappa"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein
                     4F"
                     /protein_id="NP_780499.3"
                     /db_xref="CCDS:CCDS49294.1"
                     /db_xref="GeneID:97895"
                     /db_xref="MGI:MGI:2145528"
                     /translation="MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSST
                     KVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLK
                     KKLTHDCPKKFNVRIQDFIKETFIQNDYDAFENLLISKGTERKPHMVFLKGMAGVGKT
                     LMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEIL
                     SQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLS
                     TTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFT
                     ICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQD
                     QLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLH
                     PSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSE
                     QEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKA
                     MNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNN
                     MCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFE
                     LIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSIL
                     MSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVLSNCSLSEQCWDYLSEVLRQ
                     NKTLSHLDISSNDLKDEGLKILCRSLILPYCVLESLCLSCCGITERGCQDLAEVLKNN
                     QNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCE
                     TLQTLNLMGNAFEVSRMVFFPRF"
     exon            400..1969
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2128
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2290
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2291..2458
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2629
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2800
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2974
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3527
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3499..3504
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /note="hexamer: ATTAAA"
     polyA_site      3524
                     /gene="Nlrp4f"
                     /gene_synonym="C330026N02Rik; Nalp-kappa; Nalp4f"
                     /note="major polyA site"
ORIGIN      
        1 gaaaaaaaat cactacttgt ccaaatcatc caacacttgc tccagctgga tccatagaca
       61 atccttccga ctgtatctgg cttttcccga ctttgaaatc ctgtgtctat cttcctgaag
      121 acaagatggc atctttcatt tcagattttg gccttatatg gtatttgaga gaactaaata
      181 agaaggaatt catgaagttt aaggactttc tcatacagga gattctggaa ttgaaactga
      241 aacaggtatc ttcgaccaaa gtgaagaaag catctcggga agatcttgcc aacttacttc
      301 tgaaatgtgg ggagaatcaa gcctgggata tgaccttcag aatcctccag aagatcaata
      361 ggaaagatct cactgagagg gcaacaggag cgattgttgg aaacccaaat ttatatcgag
      421 atcatttgaa gaaaaaactg acccatgatt gtcccaaaaa atttaacgtc cgtattcaag
      481 atttcattaa agagactttc attcaaaatg actatgatgc ttttgagaac cttctcatct
      541 caaagggaac tgaaaggaag ccacacatgg tgttcctgaa aggcatggct ggagttggca
      601 agacactgat gttgaaaaat ttaatgctgg cctggtcaaa aggcctggtg tttcaaaaca
      661 aattctctta cgctttctac ttctgctgtc aagatgtgaa gcagttgaag acagccagcc
      721 ttgctgaact tatctccaga gagtggccca gcccctcggc tcctatagag gagatcctat
      781 cccaacccga gaaactctta tttatcattg acagcttgga agggatggaa tgggatttaa
      841 ccaaacagga atcagagctg tgtgatgact gcatggagaa gcagccagtg agtacactgc
      901 tgagcagttt gctcaggagg aagatgctcc ctgaatcctc tctcctcctc tccactaccc
      961 cagagacttt tgagaaaatg gaggacagga ttcagtgcac agatgtgaag acagcaactg
     1021 catttgatga gaggagtatg aagatatatt tccacagatt gttccaagat aggaagagag
     1081 cccaggaggc cttcagtttg gtgagagaaa acaagcagct gttcactata tgtcaggtcc
     1141 ctctgctctg ctggatggtg gctacttgtc taaaagagga gatagagaag ggaggagacc
     1201 cagtctccct ctgccgacgt accacctccc tatataccac tcacatcttc agtttgttca
     1261 ttccccaaag tgcccagtat ccaagtaaga aaagccaaga ccagctgcag ggcttatgtt
     1321 ctctagctgc tgagggcatg tggactgaca catttgtgtt tggcaaggag gctctcagga
     1381 gaaatgggat ctttgactct gacatcccca cacttttgga cattggaatg cttggaaaga
     1441 tcagagaatt tgagaattct tacatattcc tccacccatc tgttcaggag gtctgtgctg
     1501 ccatctttta tatgctaaag aggcatgtgg aacaccctag ccaggatgtt aaaaatatag
     1561 agacagtctt gtttatgttt ttaaagaaag taaaaacaca gtggattttt ttgggctgtt
     1621 tcatctttgg tcttttacag aaatcagaac aagaaaagct aggggtattt tttggccacc
     1681 ggttgtccaa gaacatacac cataagttat atcagtgcct ggaaacctta agtggcaatg
     1741 cagagcttca agaacaaata gacggcatga gattgttttc ctgtctgttt gagatggaag
     1801 atgaagcctt cctagtaaaa gcaatgaatt gtatgcaaca gattaacttt gtggctaaga
     1861 attattctga ttttattgtt gctgcttatt gcttgaaaca ctgttctaca ctgaagaaac
     1921 tatccttttc aactgaaaat gtcctgaatg aaggagacca gagttatatg gaagagctac
     1981 ttatctgttg gaataatatg tgctctgtgt ttgtaaggag taaagacatt caggaactcc
     2041 gaataaaaga cactaatttc aatgagccag ccattcgagt tttatatgaa tctctgaagt
     2101 accccagctt cacccttaac aaacttgtgg caaataatgt gtcctttggt gataaccacg
     2161 tgctctttga gttgattcag aattccagtt tgcaatactt ggacctcagc tgctcatttc
     2221 tgtcccacaa tgaggtgaaa ctgttgtgtg atatcttgaa ccaggcagag tgcaacatag
     2281 aaaaacttat gatagcacac tgtaaacttt cacctgatga ctgcaagatc tttggctcca
     2341 tcctgatgag cagcaagtcg ttgaaggttc ttaatttggc atccaacaat ttgaatcaag
     2401 gaatatcctc actgtgcaag gctttgtgcc acccacactg tactctggag tacttagtgc
     2461 tgtccaactg ttccctcagt gagcaatgtt gggactacct ttctgaagtt cttaggcaga
     2521 acaaaactct gagccatcta gacatcagct ccaatgacct gaaggatgaa ggactgaaga
     2581 ttctctgtag gtctctgatt ctcccatact gtgtcctgga gtcactatgt ttgagctgtt
     2641 gtggaatcac cgaaaggggc tgccaggatc tggctgaagt cctgaagaac aaccagaacc
     2701 tgaagtacct acatgtttca tacaataagc taaaagacac tggtgtgatg ctgctgtgtg
     2761 atgctataaa acatcctaac tgccacttaa aggatctaca gttggaagcc tgtgaaataa
     2821 ctgatgccag taatgaggag ctttgttatg cttttatgca gtgtgagacc ctgcagacgc
     2881 tcaacctcat ggggaatgcc ttcgaagtca gtagaatggt tttctttccc aggttctgag
     2941 acagcgaaag tgttccttct gttcatgtac ttggactgtg gattactgac tttgataatg
     3001 aattccaggc atttctgctt tctgtgaaaa agaaaaatca cttcttgacc atcagaggca
     3061 gtgtggaagc agacggagaa aagaagggtg gagattctga tgcaagaacc atgggcgaac
     3121 tgtccaatga gatatgattt ctttatacct tattcagatg tgtttttgca agacagatgt
     3181 ggttttttgt ttgccctaca gtttcagaga ggccattcaa agatattcat gctaaaatga
     3241 ctactttata gtgacttttt tcccatacaa gtttcttaac actcaataca atgttaagta
     3301 tctttaatgc tttaggatct cttaacaaga gttttgcctt ttgttggatt atttattgga
     3361 gttaaagtgt aggtccaggc taatgttacc caaaaagttt ttggggaaat tttatttggc
     3421 tatgcatgag aagccttcag cagaggggta tagactggat actcagataa tggaaattgc
     3481 tgctgttttg tgttttatat taaagaatag tagtcatttc ccaagtc
//
