LOCUS       NM_001355151            3294 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus NLR family, pyrin domain containing 4B (Nlrp4b),
            transcript variant 2, mRNA.
ACCESSION   NM_001355151 XM_006539704
VERSION     NM_001355151.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Madissoon,E., Tohonen,V., Vesterlund,L., Katayama,S., Unneberg,P.,
            Inzunza,J., Hovatta,O. and Kere,J.
  TITLE     Differences in gene expression between mouse and human for
            dynamically regulated genes in early embryo
  JOURNAL   PLoS One 9 (8), e102949 (2014)
   PUBMED   25089626
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  AUTHORS   Joshi,S., Davies,H., Sims,L.P., Levy,S.E. and Dean,J.
  TITLE     Ovarian gene expression in the absence of FIGLA, an oocyte-specific
            transcription factor
  JOURNAL   BMC Dev Biol 7, 67 (2007)
   PUBMED   17567914
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3294)
  AUTHORS   Dade,S., Callebaut,I., Paillisson,A., Bontoux,M., Dalbies-Tran,R.
            and Monget,P.
  TITLE     In silico identification and structural features of six new genes
            similar to MATER specifically expressed in the oocyte
  JOURNAL   Biochem Biophys Res Commun 324 (2), 547-553 (2004)
   PUBMED   15474461
REFERENCE   4  (bases 1 to 3294)
  AUTHORS   Hamatani,T., Falco,G., Carter,M.G., Akutsu,H., Stagg,C.A.,
            Sharov,A.A., Dudekula,D.B., VanBuren,V. and Ko,M.S.
  TITLE     Age-associated alteration of gene expression patterns in mouse
            oocytes
  JOURNAL   Hum Mol Genet 13 (19), 2263-2278 (2004)
   PUBMED   15317747
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151720.2.
            
            On Sep 9, 2017 this sequence version replaced XM_006539704.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066795.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AC151720.2         121033-121068       c
            37-135              AC151720.2         120729-120827       c
            136-454             AC151720.2         98487-98805         c
            455-2009            AC151720.2         93186-94740         c
            2010-2168           AC151720.2         90191-90349         c
            2169-2333           AC151720.2         89598-89762         c
            2334-2504           AC151720.2         83807-83977         c
            2505-2675           AC151720.2         82919-83089         c
            2676-3294           AC151720.2         78721-79339         c
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 6.58 cM"
     gene            1..3294
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /note="NLR family, pyrin domain containing 4B"
                     /db_xref="GeneID:210045"
                     /db_xref="MGI:MGI:3056570"
     exon            1..36
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            37..135
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            136..454
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..2769
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /note="NACHT/LRR/pyrin domain-containing protein 4b;
                     NACHT, leucine rich repeat and PYD containing 4B"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein
                     4B"
                     /protein_id="NP_001342080.1"
                     /db_xref="CCDS:CCDS20795.1"
                     /db_xref="GeneID:210045"
                     /db_xref="MGI:MGI:3056570"
                     /translation="MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWT
                     EVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHL
                     KEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLK
                     NLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPE
                     KLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCE
                     TFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQA
                     PVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDN
                     LCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQ
                     EFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKL
                     EAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNC
                     REQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSV
                     FLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQ
                     SYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQN
                     KSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYK
                     CLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKI
                     LSIENGV"
     exon            455..2009
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2168
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2333
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2334..2504
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2505..2675
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2676..3294
                     /gene="Nlrp4b"
                     /gene_synonym="E330024M09; Nalp-gamma; Nalp4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtccgcaa attttgtctt ctgcttcttt ttccttgtat aaaaaaatca ttatttgttt
       61 gaattctcca acaattgctc cagctggatc caaagacaag tctgcagact ttatctggct
      121 ttttccgact ttgaaatcca ttctctctga agacaagtcg atcttcgttt agacaaaatg
      181 gcatctctgt tttcagattt tggctttata tggtactgga aagagctaaa caagatagaa
      241 ttcatgtatt ttaaggaatt actcatacat gaaattctgc aaatgggtct aaaacagatt
      301 tcttggactg aagtaaagga agcatctcgg gaagaccttg ccatcttact ggtaaaacat
      361 tgtgacggga atcaagcctg ggatacgacc ttcagagtct tccagatgat tgggaggaat
      421 gttatcacta atagggcaac aggagagatt gctgcacact caacaatata tcgagctcat
      481 ttaaaggaga agctgaccca tgattgttct agaaagttca acatcagtat tcagaatttc
      541 ttccaggatg aatatgatca tcttgagaac cttcttgtac caaatggaac tgaaaacaat
      601 ccaaagatgg ttgtcctgca aggtgtagct ggaattggca agactattct gttaaaaaat
      661 ttaatgattg tctggtcaga aggcctggta tttcagaaca aattctctta tatcttctac
      721 ttctgctgtc atgatgtgaa gcaattgcag acagcaagcc tggctgatct gatctccaga
      781 gagtggccta gcccctcagc tcccatggag gagatcctat cccaacctga gaaactctta
      841 ttcatcattg acagcttaga agggatggaa tggaatgtta cccaacagga ttcgcagctg
      901 tgttacaatt gcatggagaa gcagccagta aatgtattgc tgagcagttt gctcaggaag
      961 aagatactcc ctgaatcatc tctcctcatc tccactagtt gtgagacttt taaggatttg
     1021 aaggactgga ttgagtacac aaatgtgaga acaataaccg gattcaagga aaacaatatt
     1081 aatatgtgtt tccacagctt gttccaagat aggaacattg cccaggaggc cttcagtttg
     1141 ataagagaaa atgagcagct gttcactgta tgtcaggccc ctgtggtctg ctacatggtg
     1201 gctacttgtc ttaaaaatga gatagagagt ggaaaagacc cagtctccat ctgccgacgt
     1261 accacctccc tgtataccac tcacatctta aatttgttca ttccccacaa tgcccaaaat
     1321 ccaagtaaca atagcgaaga cctgctggat aacttgtgtt ttctagctgt agagggcatg
     1381 tggactgata tatctgtgtt taatgaggag gctctaagga gaaatgggat catggattct
     1441 gacatcccca cactgctgga tattggaatt cttgagcaga gcagggaatc tgaaaattct
     1501 tacatattcc tccacccgtc tgtccaggag ttctgtgcgg ccatgtttta tctgctacat
     1561 agtgaaatgg atcactcttg tcagggtgtt tactttatag aaacattcct gtttactttt
     1621 ctaaacaaga tcaaaaaaca gtgggttttt ttgggctgtt tcttctttgg tcttttacat
     1681 gaaacagaac aagaaaagct ggaggcattt tttggctacc acttatctaa agaattaagg
     1741 cgacagttgt ttttgtggct ggaactccta ttggacactt tacatcctga cgtaaaaaaa
     1801 ataaatacca tgaagttctt ttactgtctg tttgagatgg aagaggaagt ctttgtacag
     1861 tcagcaatga actgtaggga acagattgac gttgtggtta agggttattc tgattttatt
     1921 gttgctgcct actgcttaag ccatggctct gcactgacag acttctccat ttcagctcaa
     1981 aatgtgctga atgaagagct aggccagagg ggaaagctac tcatactttg gcatcaaata
     2041 tgctctgtgt tcctaaggaa taaagatatc aaaacactca gaatagaaga cactattttc
     2101 aatgaaccag tctttaaaat cttttattct tatttgaaga actccagctg tatccttaaa
     2161 acacttgtgg catataatgt ttccttttta tgtgataagc gcctattctt ggaattgatt
     2221 caaagctaca atttggagga attgtatctc agaggcacat tcctctccca cagtgatgtg
     2281 gaaatgttgt gtgatatctt gaaccaggca gagtgcaaca tacgcatact ggatttagct
     2341 aactgttccc tctgtgagca ttcttgggac tacctttctg atgttcttag gcagaacaaa
     2401 tccctgagat acctaaacat cagctacaat aacctgaagg atgaagggct gaaggctctc
     2461 tgtagagctc tgactctccc aaactctgct ctgcattcac taagtttgga agcctgtcaa
     2521 ctgactggtg cctgttgtaa ggaccttgct tctactttta cgcgatataa atgcctgcgg
     2581 aggatcaacc tggcgaagaa ctccttgggc ttcagtggat tgtttgtgct gtgtaaggct
     2641 atgaaagacc aaacgtgtac cttgtatgag ctaaaactgc gaatggctga ctttgatagc
     2701 gattcccagg aatttctact ttctgagatg gaaagaaata aaatcttgag catcgaaaat
     2761 ggtgtgtaag cagaagcaga aatcaagggt ggacattctg atgcaagaac aatggatgta
     2821 ttgtgaactc aaactacttc tgaatgaaag agaggaggat ctttattttg tcctattgtg
     2881 taaaaattac aggtcactaa cactgcagag acaggatttc tttttgccac attcagatga
     2941 gttttacaag atatatgtgg cttccttttc gcactacagt ttcagacact catgctaaaa
     3001 tgactgtctt ataatgatgt ttttctaata caggtttctt aagcacctaa taaagggtaa
     3061 aatatcttta agtagttgtt tggaatctca taacaagagt tttactttat tttgtattac
     3121 tggagctata gtgtaagtcc aggcaataat gatacccaaa aggttgtggg gaagttttag
     3181 ttggctatgc atgtaaagcc aatagcagta gcatgagcaa ctggacactc agataatgga
     3241 aactattgct gtttttctgt tttgtattaa agaataacat aagcattatc caaa
//
