LOCUS       XM_006532858            3930 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus NLR family, pyrin domain containing 3
            (Nlrp3), transcript variant X1, mRNA.
ACCESSION   XM_006532858
VERSION     XM_006532858.2
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000077.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006532858.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3930
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="11"
     gene            1..3930
                     /gene="Nlrp3"
                     /gene_synonym="AGTAVPRL; AII/AVP; Cias1; FCAS; FCU; Mmig1;
                     MWS; NALP3; Pypaf1"
                     /note="NLR family, pyrin domain containing 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 3 mRNAs, 7 ESTs, 7 long SRA reads, 8 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:216799"
                     /db_xref="MGI:MGI:2653833"
     CDS             137..3238
                     /gene="Nlrp3"
                     /gene_synonym="AGTAVPRL; AII/AVP; Cias1; FCAS; FCU; Mmig1;
                     MWS; NALP3; Pypaf1"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 3
                     isoform X1"
                     /protein_id="XP_006532921.1"
                     /db_xref="GeneID:216799"
                     /db_xref="MGI:MGI:2653833"
                     /translation="MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQM
                     EKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSM
                     VCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDL
                     NSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTV
                     VFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCW
                     PDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRK
                     KLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAF
                     RLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSR
                     GGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEV
                     DCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKF
                     EKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPS
                     QLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFF
                     HNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSL
                     TELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLV
                     ELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTR
                     LYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHL
                     YLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLN
                     LGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFE
                     ISW"
ORIGIN      
        1 gcccaggtcc tagcctcgtc accatgggtt ctgaggaact tttcttccat ggctcaggac
       61 atacgtctgg atcaagctaa gagaactttc tgtgtggacc taagccccga gaccctcgaa
      121 agggctgctg ctgaagatga cgagtgtccg ttgcaagctg gctcagtatc tagaggacct
      181 tgaagatgtg gacctcaaga aattcaaaat gcatttggaa gattacccgc ccgagaaagg
      241 ctgtatccca gtccccaggg gccagatgga gaaggcagat cacttggatc tagccacact
      301 catgattgac ttcaatggcg aggagaaggc ctgggccatg gctgtgtgga tctttgctgc
      361 gatcaacagg cgagacctct gggaaaaagc taagaaggac cagccagagt ggaatgacac
      421 gtgtacatca cattcctcta tggtatgcca ggaggacagc cttgaagaag agtggatggg
      481 tttgctggga tatctctccc gcatctccat ttgtaaaaag aagaaagatt actgtaagat
      541 gtacagacga catgtgagaa gcaggttcta ctctatcaag gacaggaacg cgcgtctagg
      601 tgagagtgtg gacctcaaca gtcgctacac gcagctccaa ctggtcaagg agcatccaag
      661 caagcaggag cgggagcatg aactcctgac catcggccgg actaaaatgc gggacagccc
      721 catgagttcc cttaagctgg agctgctgtt tgagcccgag gacgggcact cggagcctgt
      781 gcacacagtg gtgttccagg gagcagcagg catcgggaaa accatcctag ccaggaagat
      841 tatgttggac tgggcactgg gaaagctctt caaagacaaa tttgactatt tgttctttat
      901 ccactgccga gaggtgagcc tcaggacgcc aaggagtcta gcagacctga ttgtcagctg
      961 ctggcctgac ccaaacccac cagtgtgcaa gatcctgcgc aagccttcca ggatcctctt
     1021 cctcatggat ggctttgatg agctacaagg ggcctttgac gagcacattg gggaggtctg
     1081 cacagactgg caaaaggctg tgcggggaga cattctgcta agcagcctca tccgaaagaa
     1141 actgctgccc aaggcctctc tgctcataac gacgaggccg gtagccttgg agaaactgca
     1201 gcatctcctg gaccaccccc gccatgtgga gatcctaggt ttctctgagg ccaaaaggaa
     1261 ggagtatttc tttaagtatt tctccaacga gctgcaggcc cgggaggcct tcaggctgat
     1321 ccaagagaat gaggtcctct ttaccatgtg cttcatcccc ctggtctgct ggattgtgtg
     1381 cacggggcta aagcaacaga tggagaccgg gaagagcctg gcccagacct ccaagaccac
     1441 tacggccgtc tacgtcttct tcctttccag cctgctgcaa tcccgggggg gcattgagga
     1501 gcatctcttc tctgactacc tacaggggct ctgttcactg gctgcggatg gaatttggaa
     1561 ccagaaaatc ctatttgagg agtgtgatct gcggaagcac ggcctgcaga agactgacgt
     1621 ctccgctttc ctgaggatga acgtgttcca gaaggaagtg gactgcgaga gattctacag
     1681 cttcagccac atgactttcc aggagttctt cgctgctatg tactatttgc tggaagagga
     1741 ggcagagggg gagaccgtga ggaaaggacc aggaggttgt tcagatcttc tgaaccgaga
     1801 cgtgaaggtc ctactagaaa attacggcaa gtttgaaaaa ggctatctga tttttgttgt
     1861 ccgattcctc tttggccttg taaaccagga gagaacctct tatttggaga agaaactaag
     1921 ttgcaagatc tctcagcaag tcagactgga actactgaag tggattgaag tgaaagccaa
     1981 ggccaagaag ctgcagtggc agcccagcca actggaactg ttctactgcc tgtacgagat
     2041 gcaggaggaa gactttgtgc agagtgccat ggaccacttt cccaaaattg agatcaacct
     2101 ctctaccaga atggaccacg tggtttcctc cttttgtatt aagaactgtc atagggtcaa
     2161 aacgctttcc ctgggttttt ttcacaactc gcccaaggag gaagaagaag agaggagagg
     2221 aggtcgaccc ttggaccagg ttcagtgtgt tttcccagac actcatgttg cctgttcttc
     2281 cagactggtg aactgctgcc tcacttctag cttctgccgt ggtctcttct caagtctaag
     2341 caccaaccgg agcctcactg aactggacct cagtgacaat actctgggag acccgggcat
     2401 gagggtgctg tgtgaggcac tccagcaccc aggctgtaac attcagagac tgtggttggg
     2461 gcgctgcgga ctgtcccatc aatgctgctt cgacatctcc tctgtcctga gcagcagcca
     2521 gaagctggtg gagctggacc tcagtgacaa tgccctgggg gactttggaa tcagattgct
     2581 gtgtgtggga ctgaagcacc tgctctgcaa cctccagaaa ctgtggttgg tgagctgctg
     2641 tctcacatcc gcgtgttgtc aggatctcgc attggttctg agctccaacc attctctgac
     2701 cagactgtac attggagaaa atgccttggg agactcagga gtccaagttt tgtgtgaaaa
     2761 gatgaaggac ccacagtgta acttgcagaa gctggggttg gtgaattccg gccttacttc
     2821 aatctgttgt tcagctctga cctctgtgct caaaaccaac cagaacttca cacacctcta
     2881 tctacgaagc aatgcccttg gagacacagg actcaggctc ctctgtgagg ggcttctgca
     2941 cccggactgt aaactacaga tgctggaatt agacaactgc agcctcacct cacacagctg
     3001 ctggaatctc tccacaattc tgacccacaa ccacagcctt cggaagctga acctgggcaa
     3061 caatgatctt ggcgatctgt gcgtggtgac cctctgtgag gtgctgaaac agcagggctg
     3121 cctcctgcag agcctacagt tgggtgaaat gtacttaaat cgtgaaacaa aacgtgcctt
     3181 agaagcgctc caggaagaaa agcctgagct gactatagtc ttcgagattt cctggtaggc
     3241 gtggaagcag gaccaccagg tgcctcggtc ctgccccaag tcctgcccca agccccagtg
     3301 cgcactgctc ttcactgcta tcaagccctc cttcaccatc aggatcacag ccgaggctct
     3361 tctggtatag ggtctggagc aaaggcttgt gtgggaccaa atatttttcc tcacatcgat
     3421 aacgtgaaac tgccagaggc tgcccttccc atcatatcct cagtgggcaa ggtgttccct
     3481 cttggtgact tcatggaaac agcttcaaga aaacgccttt tctgtcctcc cccgccctcc
     3541 tcttactcct gcccctcctc ctcctcctcc tcccctcccc ccccctcctc ctccgcttct
     3601 ccccccacct gtctttctct ctctgggcct ctggtttttt gacctttgcc cataccttca
     3661 gtcttgtctt cctgttaact gaccatcccg cataaggagc tgcccgtggg ctagatggaa
     3721 ggtttgtggc agcctctcag ctacattgtt tgtttttatt ttttaatagt tatgatttct
     3781 ctttagctac ctgaaaactc agagatttat aaaacccatt tttgtattta ttgtatgttt
     3841 gtactgcttt cttaatttaa aaatgtatct agaattcttt taagttattt atccaaacta
     3901 ctaaaaataa atcagtttac acatttaaaa
//
