LOCUS       XM_017314354            4919 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus NLR family, pyrin domain containing 1A
            (Nlrp1a), transcript variant X1, mRNA.
ACCESSION   XM_017314354
VERSION     XM_017314354.3
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000077.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_017314354.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4919
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="11"
     gene            1..4919
                     /gene="Nlrp1a"
                     /gene_synonym="CARD7; DEFCAP; Gm14; Gm15; NAC; Nalp1;
                     Nalp1a; Nlrp1; PP1044"
                     /note="NLR family, pyrin domain containing 1A; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 7 mRNAs, 3 ESTs, 24 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     2 samples with support for all annotated introns"
                     /db_xref="GeneID:195046"
                     /db_xref="MGI:MGI:2684861"
     CDS             466..4014
                     /gene="Nlrp1a"
                     /gene_synonym="CARD7; DEFCAP; Gm14; Gm15; NAC; Nalp1;
                     Nalp1a; Nlrp1; PP1044"
                     /codon_start=1
                     /product="NACHT, LRR and PYD domains-containing protein 1a
                     isoform X1"
                     /protein_id="XP_017169843.1"
                     /db_xref="GeneID:195046"
                     /db_xref="MGI:MGI:2684861"
                     /translation="MEESQSKQESSTKVAQHEGQEDVDPTFKTKKLMEVELMKHRVQL
                     ERNLKLRTFPGARTKQVKEALYPLLTWSSKSKNLFQNFTKLLLFKKLCQRGSENLVRE
                     SWYPCVPEEEAHMIDIQDLFGPNLGTQKKPQLVIIEGAAGIGKSTLARLVKRAWKEGK
                     LYRNDFHHVFFFSCRELAQYEQLSLAELIVQGQEVPTAPIRQILSHPEKLLFILDGID
                     EPAWVLADQNPELCLHWSQTQPVHTLLGSLLGKSILPGASFLLTTRTTALQKFIPSLE
                     QPCQVEVLGFTLFERKNYFYKYFGKKKGGVTTFTLVKSNSALLTLCEVPWVCWLVCTC
                     LKKQMEQGGELSLTSQTTTALCLKYLSLTIPGQHMRTQLRDLCSLAAEGVCQRRTLFS
                     ESDLCKQGLDEHAIASFLKIGVLQKQASSLSYSFAHLCLQEFFAAMSYILDDSEERHA
                     DMKNDRIVETLVERYGRQNLFEAPTVRFLFGLLSKEELKKIEKLFSCSLHGKTKLKLL
                     WHILGKSQPHQPPCLGLLHCLYENQDMELLTHVMHDLQGTIVPGPDDLAHTVLQTNVK
                     HLVIQTDMDLMVVTFCIKFCCHVRSLQLNRKVQQGHKFTAPGMVLYRWTPITDASWKI
                     FFSNLKLARNLEELDLSGNPLSYYAVHSLCTTLRKRGCQLKTLWLVECGLTSTYCSLL
                     ASVLSARSSLTELDLQLNDLGDGGVKMLCEGLRNPACNLSILWLDQASLSDQVIAELR
                     TLEAKNPKLLISSTWKPHVMVPTMNMDKEEVGDSQALLKQQRQQSGDKHMEPLGTEDE
                     FWGPTGPVTTEVVDRERNLYRVQLPMAGSYHCPSTGLHFVVTRAVTIEIEFCAWSQYL
                     DKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVALQEGIVDSSLFHVAHFQEHGMVL
                     ETPARVEQHYAVLENPSFSPMGILLRMIPAVGHFIPITSTTLIYYHLYLEDVTFHLYL
                     VPNDCSIRKAIDDEEMKFQFVRINKPPPVDALYLGSRYIVSSSKLVEIIPKELELCYR
                     SPGESQLFSEIDIGHMDSEIKLQIKDKRHMNLKWEALLKPGDLRPALPKIATAPKDAP
                     SLLHFMDQHREQLVARVTSVDPLLDKLHGLVLSEDSYEVVRSETTNQDKMRKLFSLSR
                     SWSWDCKDQFYQALKETHPHLVMDILEKLGGVSVKS"
ORIGIN      
        1 actaatggaa gagggaactg agctcagaca tgagtcctgt ggtcaggcaa gcagggcttt
       61 ctgcaaaccc ggaagaagct ctcaccctga ctcctccagc ccaggcatct gcagagactt
      121 aacaggaaac aagctgagta atgttcaacc tccattccca gtgttcagag gaagtacatc
      181 tgccgttctc tgatgcctgc cttcctgaaa atgggccaga gtctctttca cttttggaga
      241 ccagtttctt agctgaggag ccttgttcaa agacacacac tccagtgggc cccatagagg
      301 agcagggtct cctctatcac ttctgatcaa acacccattc acagagcaga actacctggc
      361 agagacaaga agccactggt ctcctgcttg caacaacaga agagcgtctt gaagcaataa
      421 gagcacaaac tgctcagaga agcagtattc aagggctcta tcatcatgga agaatctcag
      481 tccaagcagg aaagtagcac aaaagtggct cagcatgaag gtcaagagga tgtggaccca
      541 accttcaaaa caaagaaact tatggaggtg gagctaatga agcacagagt gcagctagag
      601 aggaacttga agctaagaac ctttccagga gcacgtacga agcaagtaaa agaggctctt
      661 taccctcttc taacatggtc atcaaaaagc aagaatctgt tccaaaattt cacaaaacta
      721 ctactcttta aaaaattgtg ccaaagaggc tcagaaaact tggtcaggga aagctggtat
      781 ccatgtgtac cagaagaaga agcacatatg attgacatcc aagatttatt tggcccaaac
      841 ttaggtactc agaaaaagcc tcaattagtc ataatagaag gagctgctgg gattgggaag
      901 tcaacactgg ccagacttgt gaagagagcc tggaaggaag gcaagcttta caggaatgac
      961 ttccatcatg tcttcttctt cagctgcaga gagctggccc agtatgagca gctgagtctg
     1021 gctgagctca tagtacaagg ccaggaagtg cccacagctc ccattaggca gatcctgtct
     1081 caccctgaga agttgctctt cattctggat ggcatagatg agccagcatg ggtcttagca
     1141 gaccagaatc ctgagttatg tcttcactgg agtcaaaccc agcctgtgca cactctgctg
     1201 ggcagtttac ttgggaaatc catccttcct ggggcttcct tcttgctcac aactcgcacc
     1261 acagctctac agaaattcat tccttccctg gagcagccat gtcaagtgga agtcctagga
     1321 ttcactttgt ttgaacggaa aaactatttc tacaaatatt ttgggaagaa aaaaggtgga
     1381 gttactactt ttacattagt taaatcaaac tcagcgctcc tgactctgtg tgaagttccc
     1441 tgggtgtgct ggttggtctg cacttgcctg aaaaagcaga tggagcaggg tggagagctc
     1501 tcactgacct cacagaccac cacagcactc tgcctgaaat acctttccct gacgatccca
     1561 gggcagcaca tgaggaccca gctcagagac ctctgctcac tggctgctga gggggtctgc
     1621 caaagaagga ccctgttcag tgaaagcgat ctctgtaagc aagggttaga tgagcatgcc
     1681 attgccagtt tcctgaagat tggtgtcctt caaaagcagg ccagctctct gagctacagc
     1741 tttgcccact tgtgtcttca ggagttcttt gcagcaatgt cctacatctt ggatgatagt
     1801 gaggaaagac atgctgatat gaaaaatgac agaattgtgg aaacactggt agaaaggtat
     1861 ggaagacaaa acctgtttga ggcacccact gtgcgttttt tatttggtct tttgagtaaa
     1921 gaggaattga aaaaaataga aaagctcttt tcctgcagcc ttcatggaaa gacaaagttg
     1981 aaactactat ggcacatcct agggaaatcc caaccccatc aaccaccttg cctgggtttg
     2041 ctccactgtc tgtatgaaaa tcaggatatg gagctcctga cacacgtgat gcatgatctg
     2101 caaggaacaa tagtgcctgg accagatgat ttggcacaca cagtgttgca gacaaacgtg
     2161 aagcacctgg tgatacagac agacatggac ctcatggtgg ttactttctg cattaagttc
     2221 tgctgtcacg tgaggagtct tcagctgaac aggaaggtac agcagggaca taagtttacg
     2281 gcccctggga tggttctgta cagatggacc ccaatcactg atgccagctg gaagattttc
     2341 ttctccaatc ttaagttagc cagaaacctg gaggagttgg acctaagtgg aaatccactg
     2401 agctactatg cagtacacag tctttgtacg accctgagaa agcgtggctg ccaactaaag
     2461 actctgtggc ttgttgaatg cggcctcaca tccacatact gctcacttct ggcctcagta
     2521 ctcagtgccc gctccagcct gactgagcta gacctgcagc tgaatgacct gggtgatggt
     2581 ggtgtgaaga tgttgtgtga ggggctcagg aatcctgcct gcaatctcag catcctgtgg
     2641 ctggaccagg catctctcag tgaccaagtg attgcagagc tcagaactct ggaggcaaag
     2701 aatccaaagc tgctcatctc cagcacatgg aagccacatg tgatggtccc tacgatgaac
     2761 atggataaag aagaagtggg tgatagccag gccctactga agcagcagag acagcagtca
     2821 ggagacaaac acatggaacc tctggggact gaagatgagt tctggggccc tacaggacct
     2881 gtgactactg aggtggttga cagagagagg aacctgtacc gagttcagtt acccatggct
     2941 ggttcctacc actgtcccag tacaggactc cactttgtgg tgacaagggc agtgacaatc
     3001 gagattgaat tctgtgcctg gagccaatat ctcgacaaga ctcccttgca gcagagtcac
     3061 atggtggttg gacctctgtt tgacatcaag gctgagcaag gagctgtgac tgcagtgtac
     3121 ctccctcatt ttgtggccct ccaagaggga atcgtggaca gctccttgtt ccatgttgcc
     3181 cactttcaag aacatgggat ggtcctagaa acaccagcaa gggtggaaca gcattacgca
     3241 gtactggaaa acccaagctt ctccccaatg gggattctac tgagaatgat tccggctgtc
     3301 ggacacttca tccccatcac ttccaccaca ctgatctact atcacctcta tcttgaagac
     3361 gtcacctttc acctttacct ggtccccaat gactgcagta ttcgaaaggc cattgatgat
     3421 gaagaaatga agtttcagtt tgtgcgcata aacaagccac ccccagtaga cgctctttat
     3481 cttggttccc gctatatcgt gtcttcctcc aaattggtgg aaattatccc aaaggaacta
     3541 gagctgtgct accgaagccc tggggaatcc cagctcttct ctgagatcga cattgggcac
     3601 atggattcag agattaagct gcaaatcaaa gacaagaggc acatgaatct caaatgggag
     3661 gccttgctga aaccagggga tctcagacct gcactgccca agattgctac agcccccaaa
     3721 gatgctcctt ccttgctgca cttcatggac cagcatcggg agcagctggt ggcccgagtg
     3781 acatctgtag atcctctctt ggacaagctg catggtctgg tgctgagtga agattcctat
     3841 gaagtagtgc ggtctgagac cacaaaccaa gacaagatga ggaagctctt cagcctcagc
     3901 cggtcctgga gctgggattg caaagaccaa ttctaccaag ctctgaagga gacccatcct
     3961 cacctggtca tggatatact tgagaagttg ggtggggtct ctgtgaaatc ctgacatcct
     4021 ggtggctgaa aagtgagcac tctccttaga gtcctgcctc tgcctgacct ttccttggtc
     4081 ctgagttgct ccatctgtaa ccaatggcca tctgagtttc ctttcttgtg gcagtgcttc
     4141 catgacattt cttggtgatc catatgatcc cttttggcct tccccagcca tatgttaatg
     4201 tggaataagc atctcagaaa aaatccagtg gggccatgtc tattcagacg ttgtccccca
     4261 tgttcttatg atcaaagcag ccagtctaga gacagcctga cccaccatga atgcaagcag
     4321 ggctgaggat catgggactg gaaagtgagt gtcttatgaa taggaaagga agggggcttt
     4381 ttaaactcat gttgtgtgct cagaaacaga ggtgtagaga agtcacatgg tgcagcatgg
     4441 gactcactgt cagaaacacc ccagattcag tgcacattgt aatttaatct tgggcacttg
     4501 catatacaca tgccttctgt tcttgtgatg aatttgcaaa cctcgcattt tgttatatca
     4561 tcccatatgg aggtgtgtgt cacagcttag gaaactgata tgtgatggta gaccagatga
     4621 ctgaacagag gctcagtggt tagcagttgc tcttgagatg gtcagagtcc tattcccagc
     4681 acccatttca ggcagctcac aactgtgaat aacaccaacc tcactggatc caacagcctc
     4741 cttcccactt cttggtcacc catatataca ttcacatgca caaaataggt ttttaatttt
     4801 tataaaagaa tgaataataa aatgggattc ttctccattg ctcacccatc tgtagtctcc
     4861 cctcccccag cctgaaacct gcttgctcag gggtggagct tcctgctcat ttgttctgc
//
