LOCUS       NM_001081205            4205 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus NIPA-like domain containing 1 (Nipal1), mRNA.
ACCESSION   NM_001081205 XM_355676
VERSION     NM_001081205.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4205)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4205)
  AUTHORS   Manialawy,Y., Khan,S.R., Bhattacharjee,A. and Wheeler,M.B.
  TITLE     The magnesium transporter NIPAL1 is a pancreatic islet-expressed
            protein that conditionally impacts insulin secretion
  JOURNAL   J Biol Chem 295 (29), 9879-9892 (2020)
   PUBMED   32439805
  REMARK    GeneRIF: The magnesium transporter NIPAL1 is a pancreatic
            islet-expressed protein that conditionally impacts insulin
            secretion.
REFERENCE   3  (bases 1 to 4205)
  AUTHORS   Goytain,A., Hines,R.M. and Quamme,G.A.
  TITLE     Functional characterization of NIPA2, a selective Mg2+ transporter
  JOURNAL   Am J Physiol Cell Physiol 295 (4), C944-C953 (2008)
   PUBMED   18667602
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC122733.11.
            
            On Feb 6, 2007 this sequence version replaced XM_355676.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK075654.1, AK014427.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               AC122733.11        57666-57803         c
            139-405             AC122733.11        46651-46917         c
            406-462             AC122733.11        44787-44843         c
            463-553             AC122733.11        41975-42065         c
            554-714             AC122733.11        38663-38823         c
            715-4205            AC122733.11        34521-38011         c
FEATURES             Location/Qualifiers
     source          1..4205
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 38.44 cM"
     gene            1..4205
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /note="NIPA-like domain containing 1"
                     /db_xref="GeneID:70701"
                     /db_xref="MGI:MGI:1917951"
     exon            1..138
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..1343
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /note="NIPA-like protein 1; non-imprinted in
                     Prader-Willi/Angelman syndrome region protein 3 homolog"
                     /codon_start=1
                     /product="magnesium transporter NIPA3"
                     /protein_id="NP_001074674.1"
                     /db_xref="CCDS:CCDS39111.1"
                     /db_xref="GeneID:70701"
                     /db_xref="MGI:MGI:1917951"
                     /translation="MGVQLRLPPGEPCHEGYVLSLVCSNSSRASCEITNVSESLPYPV
                     VYTNLNSSKTNFSISASVENKYNLYVGLVLAISSSVFIGSSFILKKKGLLQLADKGIT
                     RAGQGGHSYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLISAILSSY
                     FLNERLNIHGKIGCILSVLGSTVMVIHAPQEGEVTSLHEMEMKLRDPGFVSFAVIISV
                     ISLVLILIVAPKKGQTNILVYIAICSLIGAFSVSSVKGLGIAIKELLERKPVYKDPLF
                     FILLTMLALSVTTQINYLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMKA
                     GDIIGTLSGFFTIINGIFLLHAFKNTNITWSELMSTAKKEALSPNGNQNSYVLLENAD
                     FSASGYDDDITLFSRTNDQSSHKL"
     exon            139..405
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     exon            406..462
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     exon            463..553
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     exon            554..714
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     exon            715..4205
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4149..4154
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /note="hexamer: AATAAA"
     polyA_site      4198
                     /gene="Nipal1"
                     /gene_synonym="3830408G10Rik; Npal1"
                     /note="major polyA site"
ORIGIN      
        1 gactccaccg atccgccgga acgaaagcgg gtcccgggac actggtgtgt gagaaactat
       61 tgctagcaca gaggaagccc ggtccccagg ccatgggggt acagctgagg ctgccacccg
      121 gagagccctg ccatgaaggg tatgtactgt cgctggtctg ctccaactct tcccgggctt
      181 cgtgcgagat cacaaatgtg tcagagtcgc tgccttatcc tgtcgtctac acgaacctga
      241 attcctctaa aaccaacttc agcatttcag caagtgtaga aaacaaatac aatctgtatg
      301 tgggcttggt attggccata agctccagcg ttttcattgg ctctagtttc atactcaaaa
      361 agaagggtct cttgcaactg gccgacaagg gcatcaccag agcagggcaa ggtggacatt
      421 cttacctcaa ggaatggttg tggtgggcag gactgctgtc aatgggagcc ggagaggctg
      481 cgaacttcgc cgcttatgcc tttgcgcctg ccaccttggt caccccactg ggggctctga
      541 gcgttctcat aagtgcaata ttgtcttcct attttttaaa tgagcgcttg aatattcacg
      601 ggaaaatagg ctgcatttta agcgtattgg ggtcaactgt gatggttatc cacgccccac
      661 aagagggaga agtcacatct ttgcatgaaa tggaaatgaa attgagagat ccagggttcg
      721 tttcctttgc tgtgatcatc tctgtgatct cactggtgct gattttgatt gtggccccca
      781 agaaaggaca gactaatata ttagtctata tcgcaatctg ctctttgatt ggagcgtttt
      841 ccgtctcttc tgtcaaaggc ttgggaattg ccattaagga actgctggaa cggaagcctg
      901 tttacaagga tcccctgttc ttcatcctgt tgaccatgct tgcactttcc gtgaccaccc
      961 agattaacta tctcaacaag gccctggaca ctttcaacac atccctggtg actcccattt
     1021 attacgtgtt cttcacatcc atggtggtaa cttgttctgc catcctgttc caggagtggt
     1081 atggcatgaa agctggagat atcatcggta ccctgagcgg gttcttcacc atcatcaatg
     1141 gcatcttcct cctacatgct tttaaaaaca ccaacatcac ctggagtgaa ctcatgtcta
     1201 ctgctaagaa agaagccctt tctccaaatg gcaatcagaa cagttatgtt ttactagaga
     1261 acgcagactt ctcagcctct gggtatgatg acgacatcac cctgtttagc aggaccaatg
     1321 accaaagtag ccataaactt tgaacttcaa ccaagacatc caaagcaata tttattcttg
     1381 gaaggtctat ttgcacgtta gcatgtataa cactgtataa atcctctgaa tgggaggcca
     1441 agcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaactttgct ctgcaaagcc tccaaattgg
     1501 aaaatcaagt ttaatcttct tctagaagat tcgtgtcttt cttttatgtt ttcaaaacca
     1561 ccgaaacagt ccctgagctc aacagaagcc aaagacatac atttgtctca gaataattct
     1621 tctgctcaat ggatttggca ctgccaggtg gcgcttcatc cccgcctggt cttggactcg
     1681 gcgactcaca gatctgttaa ctgtcttctg accgagcaga gtctcagacg ccatcgtctg
     1741 atgggtcata atctcaagct attaaatcta agagatggga gcactggtgt attgacctct
     1801 ggtctgcaat gccttctttc taaactacac agcagatagg caaaatgtta aagatcatac
     1861 tggactaaaa tgtttatggc acattttttt ttctttttcc caaacacaca catgattatg
     1921 tcagagaaac tattaacatg gacctggata atgtaagcaa aacatgtttt ctggaaatcc
     1981 caagtgaatt tagcttttta caacagtcat tttgttcctt tttcctattg tttttttggt
     2041 tttggcatgt tttgctttgt tttgtttttt ggtgttttgg cggtgggatg ttttcgatcg
     2101 gcttgttttc ttgcttgctt atctttcaga cacattcttg ctatgtgacc caggctggcc
     2161 tcaagttcag caccccttgg cttccatctc ctgagtgttt gggttcaagg tgtgtaccat
     2221 cacgccagct tctttttgaa aaactactgt tccaccatag atttcttctt gttgacatca
     2281 aggttttgta aaaacaatca gtacacaatg tgatgttcca cttttctcaa aggtcttatc
     2341 cctaaaaggt gggtcatcca aaactgagaa caaccaacag attcctttta cagctttaat
     2401 gttcttttta aatttgccca ttttcacctt aataaggaaa ttataaacag tttctaactt
     2461 ttcagaatgg acacagccta ctgttttcag taacaggtgc cttttttttt ccattgataa
     2521 ttatgtaggg agagagaaat tcctttaaaa aagaaaaaag tccgaagaca tgctacagga
     2581 agaatctttt gctcatttaa attttgcatt tgatttctct gactcattct agactcatgc
     2641 tcttagacct ttcagcaaga ggcactgttg aatgcagtta actgtgctgt gtgtttggga
     2701 gggaggataa tccatgggca tcccatgact taatacctca aggcatatac atgtttactt
     2761 cctgccctga cccactttgg gtaacagata tagaaactgt gaacacgttt gtagaaaatt
     2821 atcttctgaa atggtaggat gtttgaaacc tgtacaaatt cttttactgg ctttccttgt
     2881 tgctttgata atctcacctg gttcccccgg ggtatcttct tggtaaggat atcagtcatt
     2941 tctctagaca tctttcctca ggttgtggcc gttccccgtt ctagtgatct tgattttttt
     3001 ttagacattt atgaaatgtc ctttgttact ttacgcctta gctgtcaagt tttgcccttg
     3061 gtacgttgtg cacaggtcaa agactcctgg aacacaagaa ttgatgtttc ctggtttgga
     3121 aaatgaactg gtgttgacat atacgcccag gagaaagact gagagatttc atcacttgtc
     3181 atatatagag aaacaaaaaa aattgacaaa tattttcaaa tctctggaaa gattgctggt
     3241 gagcatatat gtttaaaaat taaaatgcta ctataaatct aataccacag ctgaatcttt
     3301 ctcgagtggg aagatgctgc tggaggaaga gtaaactact gcatccctct gggacgtttc
     3361 gaactgctcg tctcttactc gtgtgcattg gaattcgtat ccttgtcatc gtatagacgt
     3421 gagttatttg gtggatatca gcgaatatgt aaagaaaatg gctttgcctt ttgaattata
     3481 acttcaccac taggtcaatg gttaatgatt ttttgtccag agtaaaagat attcataaaa
     3541 ttcaaacatt ggattaaatt aacacatttc ttttttaaaa aggaagaaaa tactaagcta
     3601 cataaatgga aagcttaaat tatgcccagt aaataatagg cacttcacta aagttggttc
     3661 tcattgaacc agacttctaa tcctcgctct tcttacaagg gagagagaga gagagagaga
     3721 accactgagc acaagtttct tcatcgttcc tcagtttcag tcacattatt aattttagac
     3781 aatccaagtg aaggcaaatt catcattgtc cactctccat cacaatgcag aaccattcca
     3841 acaaaaatat tttccctaga gaggggggat gtagctcact gctccctctg catgcacaca
     3901 ggcactgggt ttgatcctca acacaagggg ccgaataata aaaccagtag aaccaaaaca
     3961 taatgtcatc tttaccttca aaagctttgg aggtggcagg ggtcgggtgg gaaggaccat
     4021 atgaatgttt tgaatgttct caaatatttt tgataaactg tattggtgag agtttatatt
     4081 tttcaaatgt ttataagtac tattcatttt ggatagttta tacatctgta atgtttctgt
     4141 atatttccaa taaaataata ttgttttctt gtgccttttg gtactgaggt tacaggcatt
     4201 gagaa
//
