LOCUS       NM_146119               3693 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus niban apoptosis regulator 2 (Niban2), mRNA.
ACCESSION   NM_146119
VERSION     NM_146119.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3693)
  AUTHORS   Vazquez-Sandoval,A., Velez-delValle,C., Hernandez-Mosqueira,C.,
            Marsch-Moreno,M., Ayala-Sumuano,J.T. and Kuri-Harcuch,W.
  TITLE     FAM129B is a cooperative protein that regulates adipogenesis
  JOURNAL   Biochem Biophys Res Commun 638, 66-75 (2023)
   PUBMED   36442234
  REMARK    GeneRIF: FAM129B is a cooperative protein that regulates
            adipogenesis.
REFERENCE   2  (bases 1 to 3693)
  AUTHORS   Oishi,H., Itoh,S., Matsumoto,K., Ishitobi,H., Suzuki,R., Ema,M.,
            Kojima,T., Uchida,K., Kato,M., Miyata,T. and Takahashi,S.
  TITLE     Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice
  JOURNAL   J Biochem 152 (6), 549-555 (2012)
   PUBMED   22977259
  REMARK    GeneRIF: Fam129b in epidermal keratinocytes accompanied by
            alteration of wound healing-related gene expression is necessary
            for regulation of cell motility.
REFERENCE   3  (bases 1 to 3693)
  AUTHORS   Chen,S., Evans,H.G. and Evans,D.R.
  TITLE     FAM129B/MINERVA, a novel adherens junction-associated protein,
            suppresses apoptosis in HeLa cells
  JOURNAL   J Biol Chem 286 (12), 10201-10209 (2011)
   PUBMED   21148485
REFERENCE   4  (bases 1 to 3693)
  AUTHORS   Hutchins,J.R., Toyoda,Y., Hegemann,B., Poser,I., Heriche,J.K.,
            Sykora,M.M., Augsburg,M., Hudecz,O., Buschhorn,B.A., Bulkescher,J.,
            Conrad,C., Comartin,D., Schleiffer,A., Sarov,M., Pozniakovsky,A.,
            Slabicki,M.M., Schloissnig,S., Steinmacher,I., Leuschner,M.,
            Ssykor,A., Lawo,S., Pelletier,L., Stark,H., Nasmyth,K.,
            Ellenberg,J., Durbin,R., Buchholz,F., Mechtler,K., Hyman,A.A. and
            Peters,J.M.
  TITLE     Systematic analysis of human protein complexes identifies
            chromosome segregation proteins
  JOURNAL   Science 328 (5978), 593-599 (2010)
   PUBMED   20360068
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY341437.1, AK153489.1 and AL929154.6.
            
            On Apr 28, 2009 this sequence version replaced NM_146119.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150642.1, AK153489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                BY341437.1         3-58
            57-2936             AK153489.1         1-2880
            2937-2937           AL929154.6         11398-11398
            2938-3693           AK153489.1         2881-3636
FEATURES             Location/Qualifiers
     source          1..3693
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.09 cM"
     gene            1..3693
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /note="niban apoptosis regulator 2"
                     /db_xref="GeneID:227737"
                     /db_xref="MGI:MGI:2442910"
     exon            1..271
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..2466
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /note="niban-like protein 1; family with sequence
                     similarity 129, member B"
                     /codon_start=1
                     /product="protein Niban 2"
                     /protein_id="NP_666231.1"
                     /db_xref="CCDS:CCDS15934.1"
                     /db_xref="GeneID:227737"
                     /db_xref="MGI:MGI:2442910"
                     /translation="MGDVLSTHLDDARRQHIAEKTEKILTEFLRFYEDQYGVSLFNSM
                     RHEIEGTGPPQAQLLWRKVPLDERIIFSGNLFQYQEDNKKWRNRFSLVPHNYGLVLYE
                     NKVAYERQIPPRAVINSAGYKVLTSVDQYLELVGNSLPGTTSKSGSTPILKCPTQFPL
                     ILWHPYARHYYFCMMTEAEQDKWQAVLQDCVRHCNNGIPENSKVEGPAFTDAIRMYRQ
                     SKEQYGTWEMLCGNEVQILSNLVMEELGPALKAELGPRLKGKPQERQRQWIQISDAVY
                     RLVFEQAKVHFEDVLCKLQRARPAMEAVIRTDMDQIITSKEHLASKIRAFILPKAEVC
                     VRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKL
                     SQLAYHPLKMQSCYEKMEPLRLDGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFET
                     LLHQELGKGPTKEELCKSIQRILERVLKKYDYDSSSVRKRFFREALLQITIPFLLKKL
                     APTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYR
                     DSMVLHNSDPNLHLLAEGTPIDWGEQYGDSGDSGGGDSGGSPCPSEAATLTEKRRRAK
                     QVMSVVQDEESGLPFEAGVEPPSPASPDSVTELRGLLAQDLQAESSPPASPLLNGAPV
                     QESSQPVAVPEASPPASPLRHLPPGKAVDLEPPKPSDQETGEQVSSPGSRPPIHTTTE
                     DSAGVQTEF"
     exon            272..402
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            403..531
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            532..637
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            638..805
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            806..921
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1026
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1189
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1377
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1533
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1650
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1758
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1759..1870
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
     exon            1871..3693
                     /gene="Niban2"
                     /gene_synonym="9130404D14Rik; Fam129b; Meg-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcggggcg ggcgccgggg cttgggcgcg ggctagagag gcagcagcgg ccggagggag
       61 ggacgcggtg gggatctcgg tgggagcgca gagagagcag ccgaggcggc agcggggctg
      121 cggggcgacg gcggcagcgg ggcctgcgga ctccatggcg ccagcggcgt cagtctgagt
      181 agcggcgggc ggatccggcc gcgtcttctc ctcgccatgg gagacgtact gtccacacac
      241 ctggatgacg cacggcgcca gcacatcgca gagaaaaccg agaagatcct cacagagttc
      301 cttcgcttct atgaggacca gtatggtgtc tccctcttca atagcatgcg ccatgagatc
      361 gagggcaccg ggccaccgca ggcacagctg ctctggcgca aggtgcccct ggatgaacgc
      421 atcatcttct ccggaaacct tttccagtac caggaagaca ataagaagtg gagaaaccgc
      481 ttcagcctgg tgccccataa ctatgggctg gtgctatatg agaacaaagt ggcctatgag
      541 cggcagatac caccccgggc cgtcatcaac agcgcgggct acaaggttct cacctctgtc
      601 gaccagtatc tggagctggt cggcaattcc ctgccaggga ccacatcgaa atcaggctcc
      661 acccccatcc ttaagtgccc aacgcagttc cctctcatcc tgtggcatcc ttacgcccga
      721 cactattact tctgcatgat gacagaagcg gagcaggaca agtggcaggc agtgcttcag
      781 gattgcgttc gacactgcaa caacgggatc ccggagaact caaaggtgga gggccctgca
      841 ttcacagacg ccatccgcat gtaccgccag tcaaaggagc agtacggcac ctgggaaatg
      901 ctgtgtggca acgaggtgca gatcctaagc aacctggtga tggaggagct gggcccagcg
      961 ctgaaggcag agcttggccc acggctgaag ggaaagcctc aggagcggca gcgacagtgg
     1021 atccagatct cggacgctgt gtaccgcctg gtatttgaac aggccaaggt gcactttgag
     1081 gacgtgctgt gtaagctgca gcgggcccgg ccggccatgg aggcagtcat ccgcaccgac
     1141 atggaccaga tcatcacctc caaggagcat ctggccagca agatccgagc cttcatcctc
     1201 cccaaggcgg aggtgtgcgt gaggaaccac gtccagccct acatcccatc catcttggag
     1261 gctctgatgg tgcccaccag ccagggcttc accgaggtgc gggatgtctt cttcaaagag
     1321 gtcacagaca tgaatctgaa cgtgatcaac gagggtggca ttgacaagct gggcgagtac
     1381 atggagaagc tatcccagct ggcataccac cccctgaaga tgcagagctg ctatgagaag
     1441 atggagccac tgcggctcga cgggctgcag cagcgattcg acgtgtctag cacttccgtg
     1501 ttcaagcagc gagcccagat ccacatgcga gagcaaatgg acaatgctgt gtacaccttc
     1561 gaaaccctcc tgcaccaaga gctggggaag ggacccacca aggaggagct gtgcaaatcc
     1621 atccagcgga ttctagagcg cgtgctgaag aaatacgact atgacagcag ttctgtgcgc
     1681 aagagattct tccgagaggc gctgctgcag atcaccattc ccttcctgct caaaaagctg
     1741 gcccccacct gcaagtcgga gctgccacgc ttccaggagc tgatctttga agactttgcc
     1801 aggttcatcc tggtggagaa cacgtacgag gaggtggtgc tgcagacggt catgaaggac
     1861 atcctgcagg ctgtgaagga ggccgcagtg cagcgcaaac acaacctcta ccgtgacagc
     1921 atggttctgc acaatagtga ccccaatcta cacctgctgg ctgagggcac accaatcgac
     1981 tggggcgaac agtacggtga cagcggtgac agcggcggtg gtgacagtgg tggcagcccc
     2041 tgcccctctg aagcagccac cctcacagaa aagcgcaggc gtgccaagca ggtgatgtcc
     2101 gtggtccagg acgaggagtc ggggctgccc tttgaggctg gcgttgaacc gccatcacct
     2161 gcatccccgg acagtgtcac cgagctccga ggcctgttgg cccaggacct gcaggctgaa
     2221 agctccccac cagccagccc tcttctcaat ggggctccag tccaagagag ctcccaaccc
     2281 gtggcagtcc cagaggcctc accgccagcc tcacccctcc ggcatctccc acctggaaag
     2341 gctgtggacc ttgagccccc taagcccagt gaccaagaga ccggagagca ggtgtctagc
     2401 cccggtagcc gtccccccat ccataccacc actgaggaca gtgcgggagt gcagacggag
     2461 ttctaagcat ggcctccagg cttctgttgg actctgcacc agggcgctcc tccttgggca
     2521 ccacagcctc tcacctctgg ggaggggtac tccagtttgt gccttgtggg aaaggtggct
     2581 ggggtggtgt ggcatctcca ggggtctggc ctacccaagt cactttatgg ggttcagtac
     2641 acctgttact gccccgtttt ctgtgggctg atctccaatg ctgggtctgg ttttgagggt
     2701 ttcctctttg tgcaagggtc tggggagccc ctccatcccg ccctcgtact gttacggcgg
     2761 cagatgaaag cagtggtggt gtgactcacg tataggaagc taggaagctg tcatctcact
     2821 ctggggctcc ttgggaccaa cgtggcaagg aaaaggcaga ccaggcctct gtcccgccca
     2881 ctccctgcag gtcccaaggt tagacactgg cctcactttg ctagctactg ctgtgggagg
     2941 gcggggctta ggggtcttac aggggagtga tgctagaggt cagaggtcat gatggaatga
     3001 gaaaggccca gaatgtgtta gtctgtgcag gggaagtgtc ctgaggggga gggagcttgg
     3061 gagtgtcttt gccaggatgg caaagtgaag gtagctgaag ttggagtgtc ttgggtgacc
     3121 cgttcctgct catctggctg acaacgctca ttggcagggc ttagctgtgg gctgtttcac
     3181 tacgtgccag gaagctggtg gggctccaga gggacattga gggctatggc tctctgagac
     3241 actgctgacc attcatggcc tctgctcccg tcacctaatc ctgataattc cagacccctc
     3301 ttccaatgtc cttgtgagcc atttgggctt gtctttccct cttagtcaca agggtcaaac
     3361 caagagtcag ttagctagat gactctcccc agactctgtc gccagagttg ggagaacaaa
     3421 gcagagactg ccgctccaag gcccccagga cgaggtccct cccagtcctg tgtcccttgc
     3481 tctgtggacc tgctccccag acgcaggcct cagacccaca ggatgtggcc ggtgctcagg
     3541 gacacccagt cccctgccct cactccgagt actgacttct ttccatgttc tctagtgcct
     3601 tgggggtttc caccatcctt ccagatatgg tatgaagaat ctatgcaaac tgtgtaagct
     3661 tctgctcatc aataaacgct ttatttaaag ctc
//
