LOCUS       NM_172501               1560 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus NHL repeat containing 3 (Nhlrc3), mRNA.
ACCESSION   NM_172501
VERSION     NM_172501.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1560)
  AUTHORS   Kiyozumi,D., Sugimoto,N. and Sekiguchi,K.
  TITLE     Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1,
            and Frem2 at the basement membrane provokes Fraser syndrome-like
            defects
  JOURNAL   Proc Natl Acad Sci U S A 103 (32), 11981-11986 (2006)
   PUBMED   16880404
REFERENCE   3  (bases 1 to 1560)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK033167.1.
            
            On Apr 5, 2007 this sequence version replaced NM_172501.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033167.1, SRR1660813.105349.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1560              AK033167.1         1-1560
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 25.15 cM"
     gene            1..1560
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /note="NHL repeat containing 3"
                     /db_xref="GeneID:212114"
                     /db_xref="MGI:MGI:2444520"
     exon            1..199
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1159
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /note="NHL repeat-containing protein 3"
                     /codon_start=1
                     /product="NHL repeat-containing protein 3 precursor"
                     /protein_id="NP_766089.1"
                     /db_xref="CCDS:CCDS17345.1"
                     /db_xref="GeneID:212114"
                     /db_xref="MGI:MGI:2444520"
                     /translation="MARAWVCLAGAAFFLSCLVLHSRFCGSLVSRTFSFHVSWRMEDP
                     LFRLDLGWPKNSEYFTGATFCVAVDSLNGLVYVAQRGDNIPKVLVFSEDGYFLRAWNY
                     TVDTPHGMFVSGTPFEQSVWITDVGSGPYGHTVKKYNSLGDLVQVLGTPGKKGTGLNP
                     LQFDNPAELYVDDTGEMYIVDGDGGLNNRLVKLSQDFMILWLRGENGTGPAKFNIPHS
                     VTLDAVGRVWVADRGNKRLQVFDKDTGEWLGAWDNCFTEEGPSAVRFTPDGKYLIVAQ
                     LNLSRLSVLLAPPSGSIGDCSVVSTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQIQK
                     YIPWHSRTPAFGA"
     exon            200..352
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     exon            353..500
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     exon            501..701
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     exon            702..793
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     exon            794..906
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1560
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1226..1231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /note="hexamer: AAGAAA"
     polyA_site      1248
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /note="major polyA site"
     polyA_site      1519
                     /gene="Nhlrc3"
                     /gene_synonym="4833441N19; 8030451K01Rik; mKIAA4083"
                     /note="major polyA site"
ORIGIN      
        1 gacacccgga attagtcttc ggcggttctc cggtcgagtt tcccggtgct ttagtctgcc
       61 tctgccctag agccggcttc aggcctcgct gactttcgcc tcccagaccc tcgcgatggc
      121 gagagcctgg gtctgcctgg cgggcgccgc cttcttcctt tcctgtctgg ttttgcattc
      181 gcgcttctgt ggctcgctgg tttcaaggac attttctttt cacgtttcct ggagaatgga
      241 ggaccctctt ttccggctgg atttgggttg gcccaagaat tcggaatact tcactggtgc
      301 aacattttgt gttgcagttg attccctcaa cgggttagtt tacgtagccc aaagagggga
      361 taacatcccc aaggtattag tgttctcaga ggatggctat ttcctacgag cctggaatta
      421 tacagttgac acaccccatg gtatgtttgt ctccggcaca ccatttgaac agtccgtctg
      481 gatcacggac gtaggaagcg gaccctacgg ccatactgtt aaaaaatata attccctggg
      541 tgatcttgtt caagtcttgg gaaccccagg caagaagggc actggcttga acccgctgca
      601 gtttgacaac cctgcagaat tatatgtaga tgacacaggg gagatgtaca ttgtggatgg
      661 agatggggga ctgaataaca gactggtcaa actatcccaa gatttcatga tcctctggct
      721 gcgtggagag aatgggacag gacctgccaa gttcaacata cctcacagcg ttacacttga
      781 cgcagttggt cgggtgtggg ttgcggaccg aggaaataag aggctccaag tatttgataa
      841 ggacactgga gagtggttag gagcatggga caactgtttc acagaggagg ggccttctgc
      901 tgtgaggttc accccagatg ggaagtactt gattgtggcc cagctgaacc tcagtaggct
      961 gtcagtgttg cttgccccac cctccggaag catcggagac tgctctgtgg tcagcactat
     1021 ccagctggca gatcaggttc tgccacatct tttggaagtc gacagaaaga ctggcgcagt
     1081 gtatgtagca gaaattgggg caaaacaaat acaaaaatac atcccgtggc acagccgcac
     1141 ccctgccttc ggcgcttagt gcttccggct gggaggagct tcgggtagca cttcagagcc
     1201 acagggtcat tttcacctct tctgcaagaa aagtgtgttg ctgggtcatg aagagtcatg
     1261 ttttctcgtg gttttgggac ttggttttac aactaagtgt gtttctttct ggtggccctg
     1321 ggagttgaac tcatcacttc ctaagtgcta ggcggctgcc ctagcagggg ctacatcttc
     1381 acagaagcac cttttaaagg aagaaatgca gttctaaaat ggggccatga cgggaactgt
     1441 ggttgtaacc aagctgcttg cctgcatcga ttaactctct ctgggttcct gggtgacttc
     1501 atatgatgag tggaaactac tagttggttt agcctatgtg tattagactg tggaagagat
//
