LOCUS       NM_026890               1229 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus neuroguidin, EIF4E binding protein (Ngdn), mRNA.
ACCESSION   NM_026890 XM_127738
VERSION     NM_026890.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1229)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1229)
  AUTHORS   Udagawa,T., Swanger,S.A., Takeuchi,K., Kim,J.H., Nalavadi,V.,
            Shin,J., Lorenz,L.J., Zukin,R.S., Bassell,G.J. and Richter,J.D.
  TITLE     Bidirectional control of mRNA translation and synaptic plasticity
            by the cytoplasmic polyadenylation complex
  JOURNAL   Mol Cell 47 (2), 253-266 (2012)
   PUBMED   22727665
  REMARK    GeneRIF: poly(A) polymerase Gld2, deadenylase PARN, and translation
            inhibitory factor neuroguidin (Ngd) are components of a dendritic
            CPEB-associated polyadenylation apparatus
REFERENCE   4  (bases 1 to 1229)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   5  (bases 1 to 1229)
  AUTHORS   Tkatchenko,T.V., Moreno-Rodriguez,R.A., Conway,S.J.,
            Molkentin,J.D., Markwald,R.R. and Tkatchenko,A.V.
  TITLE     Lack of periostin leads to suppression of Notch1 signaling and
            calcific aortic valve disease
  JOURNAL   Physiol Genomics 39 (3), 160-168 (2009)
   PUBMED   19723774
REFERENCE   6  (bases 1 to 1229)
  AUTHORS   Jung,M.Y., Lorenz,L. and Richter,J.D.
  TITLE     Translational control by neuroguidin, a eukaryotic initiation
            factor 4E and CPEB binding protein
  JOURNAL   Mol Cell Biol 26 (11), 4277-4287 (2006)
   PUBMED   16705177
  REMARK    GeneRIF: a new eukaryotic initiation factor 4E (eIF4E) binding
            protein, Neuroguidin (Ngd), and its interaction with CPEB is
            described.
REFERENCE   7  (bases 1 to 1229)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CN715203.1, AK005098.1 and BC052790.1.
            
            On Aug 15, 2009 this sequence version replaced NM_026890.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052790.1, AK005098.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-119               CN715203.1         1-119
            120-1193            AK005098.1         2-1075
            1194-1229           BC052790.1         1132-1167
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 28.03 cM"
     gene            1..1229
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /note="neuroguidin, EIF4E binding protein"
                     /db_xref="GeneID:68966"
                     /db_xref="MGI:MGI:1916216"
     exon            1..135
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..1071
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /note="EIF4E-binding protein"
                     /codon_start=1
                     /product="neuroguidin"
                     /protein_id="NP_081166.1"
                     /db_xref="CCDS:CCDS36928.1"
                     /db_xref="GeneID:68966"
                     /db_xref="MGI:MGI:1916216"
                     /translation="MAAPEVLESDVSSSITLLKNLQEQVMAVTAQIQALTTKVRAGTY
                     STEKGLSFLEVKDQLLLMYLMDLSHLILDKASGASLQGHPAVLRLVEIRTVLEKLRPL
                     DQKLKYQIDKLVKTAVTGSLSENDPLRFKPHPSNMVSKLSSEDEEESEAEEGQSEASG
                     KKSAKGSAKKYVPPRLVPVHYDETEAEREQKRLEKAKRRALSSSVIRELKEQYSDAPE
                     EIRDARHPHVTRQSQEDQHRVNYEESMMVRLSVSKREKGLRRRASAMSSQLHSLTHFS
                     DISALTGGTAHLDEDQNPVKKRKKLPKKGRKKKGFRRRW"
     exon            136..195
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            196..267
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            268..405
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            406..490
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            491..543
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            544..667
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            668..836
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            837..993
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1051
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1201
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1173..1178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /note="hexamer: AATAAA"
     polyA_site      1195
                     /gene="Ngdn"
                     /gene_synonym="1500001L15Rik; neuroguidin; Ngd"
                     /note="major polyA site"
ORIGIN      
        1 gcggaaatga aagatctctt acttccattg gctgaaattt gcaaactgtg attgtctatc
       61 aaaactatga actcacgcta gctcctagga agttcgggcc cggaaagggt gggctttgcg
      121 aagatggcgg ctccggaggt gctggagtca gacgtgtcaa gttcgataac acttttgaaa
      181 aacctccagg agcaggtgat ggctgtcact gcacaaatcc aagcactgac gacaaaagtt
      241 cgagctggaa cgtattctac agagaagggt ctgagcttct tggaagtgaa agaccagctg
      301 ttgctcatgt accttatgga tctgagccac ctcatcctgg acaaggcctc tggagcatct
      361 ctgcagggac accctgcagt tttgaggctg gtggagattc gcacggtttt agaaaaactt
      421 cgtcctttgg accaaaaact gaagtatcaa attgacaaac tggtcaagac ggcagtgaca
      481 ggcagcctca gtgagaatga cccgctccgt tttaagcctc atcccagcaa catggtgagc
      541 aagttgagct ctgaggatga ggaggaaagt gaagcagaag agggccagtc tgaggcctcg
      601 gggaagaaat cggcaaaagg ctcagctaag aaatacgtcc cgccacgctt ggttccagta
      661 cattacgatg agactgaggc tgagcgggag cagaagcgcc tggagaaagc caagaggcgg
      721 gcgctgagca gctctgtcat ccgggagctg aaggagcagt actcagacgc cccagaggaa
      781 atccgggacg ctcgacaccc tcacgtcact cgccagagtc aggaggatca gcacagggtc
      841 aactatgaag agagcatgat ggtgcgctta agtgttagca agcgagagaa aggactgcga
      901 aggcgagcga gcgccatgag ctcccagctt cattccctca cacacttcag tgacatcagt
      961 gctctgacag ggggcactgc tcatctcgat gaggaccaga atcctgttaa aaagaggaag
     1021 aagctaccta aaaaaggccg gaagaagaaa ggttttcgga ggcgctggtg atgtggtgcg
     1081 cttacacgtg tacttttggt catcctggga tgcttctaac ttcactgtgt gtaggcgttt
     1141 gccttggaaa tgtggaaagt gctttactaa ataataaaat taattttgtt tacgagtgaa
     1201 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
