LOCUS       NM_001357193            2101 bp    mRNA    linear   ROD 24-DEC-2022
DEFINITION  Mus musculus nuclear transcription factor-Y gamma (Nfyc),
            transcript variant 5, mRNA.
ACCESSION   NM_001357193 XM_017320024
VERSION     NM_001357193.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Castro NE, Kato M, Park JT and Natarajan R.
  TITLE     Transforming growth factor beta1 (TGF-beta1) enhances expression of
            profibrotic genes through a novel signaling cascade and microRNAs
            in renal mesangial cells
  JOURNAL   J Biol Chem 289 (42), 29001-29013 (2014)
   PUBMED   25204661
REFERENCE   2  (bases 1 to 2101)
  AUTHORS   Oldfield AJ, Yang P, Conway AE, Cinghu S, Freudenberg JM,
            Yellaboina S and Jothi R.
  TITLE     Histone-fold domain protein NF-Y promotes chromatin accessibility
            for cell type-specific master transcription factors
  JOURNAL   Mol Cell 55 (5), 708-722 (2014)
   PUBMED   25132174
REFERENCE   3  (bases 1 to 2101)
  AUTHORS   Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K,
            Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre
            A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt
            AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,
            Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S,
            Wohnoutka P, Hawrylycz MJ, Puelles L and Jones AR.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   4  (bases 1 to 2101)
  AUTHORS   Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima
            C, Parnavelas JG and Andrews WD.
  TITLE     Robo1 modulates proliferation and neurogenesis in the developing
            neocortex
  JOURNAL   J Neurosci 34 (16), 5717-5731 (2014)
   PUBMED   24741061
REFERENCE   5  (bases 1 to 2101)
  AUTHORS   Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S,
            Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N,
            Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y,
            Okado H, Hashimoto M and Asahara H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 2101)
  AUTHORS   Maeda YY, Funata N, Takahama S, Sugata Y and Yonekawa H.
  TITLE     Two interactive genes responsible for a new inherited cataract
            (RCT) in the mouse
  JOURNAL   Mamm Genome 12 (4), 278-283 (2001)
   PUBMED   11309658
REFERENCE   7  (bases 1 to 2101)
  AUTHORS   Matuoka K and Yu Chen K.
  TITLE     Nuclear factor Y (NF-Y) and cellular senescence
  JOURNAL   Exp Cell Res 253 (2), 365-371 (1999)
   PUBMED   10585259
  REMARK    Review article
REFERENCE   8  (bases 1 to 2101)
  AUTHORS   Orita T, Shimozaki K, Murakami H and Nagata S.
  TITLE     Binding of NF-Y transcription factor to one of the cis-elements in
            the myeloperoxidase gene promoter that responds to granulocyte
            colony-stimulating factor
  JOURNAL   J Biol Chem 272 (37), 23216-23223 (1997)
   PUBMED   9287329
REFERENCE   9  (bases 1 to 2101)
  AUTHORS   Nakshatri H, Bhat-Nakshatri P and Currie RA.
  TITLE     Subunit association and DNA binding activity of the heterotrimeric
            transcription factor NF-Y is regulated by cellular redox
  JOURNAL   J Biol Chem 271 (46), 28784-28791 (1996)
   PUBMED   8910521
REFERENCE   10 (bases 1 to 2101)
  AUTHORS   Sinha S, Maity SN, Seldin MF and de Crombrugghe B.
  TITLE     Chromosomal assignment and tissue expression of CBF-C/NFY-C, the
            third subunit of the mammalian CCAAT-binding factor
  JOURNAL   Genomics 37 (2), 260-263 (1996)
   PUBMED   8921405
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY005484.1, AL606904.12, AK011327.1, AB006181.1 and BE647422.1.
            
            [WARNING] On May 15, 2023 this sequence was replaced by
            NM_001357193.2.
            
            On Oct 25, 2017 this sequence version replaced XM_017320024.1.
            
            Transcript Variant: This variant (5) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2, 4, 5 and 6 encode the same
            isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422598.950134.1,
                                           SRR7345562.861961.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               BY005484.1         1-142
            143-143             AL606904.12        63692-63692         c
            144-288             BY005484.1         144-288
            289-323             BY005484.1         290-324
            324-721             AK011327.1         170-567
            722-1339            AB006181.1         391-1008
            1340-1637           AK011327.1         1185-1482
            1638-2101           BE647422.1         29-492
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 56.52 cM"
     gene            1..2101
                     /gene="Nfyc"
                     /note="nuclear transcription factor-Y gamma"
                     /db_xref="GeneID:18046"
                     /db_xref="MGI:MGI:107901"
     exon            1..323
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            324..436
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     CDS             332..1339
                     /gene="Nfyc"
                     /note="isoform 1 is encoded by transcript variant 5;
                     nuclear transcription factor Y subunit gamma; nuclear
                     transcription factor Y subunit C; CAAT box DNA-binding
                     protein subunit C"
                     /codon_start=1
                     /product="nuclear transcription factor Y subunit gamma
                     isoform 1"
                     /protein_id="NP_001344122.1"
                     /db_xref="CCDS:CCDS18594.1"
                     /db_xref="GeneID:18046"
                     /db_xref="MGI:MGI:107901"
                     /translation="MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELP
                     LARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIA
                     MAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQ
                     QQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQTQSG
                     TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ
                     ITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQTPQVTG
                     D"
     exon            437..508
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            509..622
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            623..718
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            719..892
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1051
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1159
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1219
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..2081
                     /gene="Nfyc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggtgatga aggaattggc ggctgtcggg atgctagctg ctcaggctct ggcggcaggg
       61 cgacggtccc tctaatgcca gcgtggcggg gagtctccgg gacggagccg gaggcccaga
      121 ggagaaagag agtggtagcc tggcgtgtgg cctgcaacgg ggaggggtca ctactaatac
      181 cagaggcacg gtcaactaca agatggggtg tgcaagcccc tgctttgtaa acacggaaca
      241 gaagtgtctt cgagacctag gggtgctaga cttggaaatt gatccagctt gggaatgacc
      301 ctgagtagaa gtctgagtgc atgttgtgaa aatgtccaca gaaggagggt ttggcggtac
      361 cagcagcagt gatgcccagc aaagcctcca gtccttctgg cccagagtca tggaagaaat
      421 ccgaaactta acagtgaaag atttccgagt acaggaactc ccactggctc gtattaagaa
      481 gattatgaaa ctggatgaag atgtgaagat gatcagtgca gaagcccctg tgctgtttgc
      541 taaggcagcc cagattttta tcactgagct gactcttcga gcctggatcc acacagagga
      601 taacaagcgt cgtactcttc agaggaatga tattgccatg gcaattacaa aatttgatca
      661 gttcgacttt ctcatcgata ttgttccaag agatgaactg aaacctccaa agcgccagga
      721 ggaggtacgc cagtctgtga ctcctgcgga gcctgtccag tactacttca cgctggctca
      781 gcagcccact gctgtccagg tccagggaca gcagcaaggc cagcagacca ccagttctac
      841 gaccaccatc cagcctggac agatcatcat tgcacagcct cagcagggtc agaccacacc
      901 cgtgaccatg caggttggag aaggtcagca ggtgcagatt gtacaggccc aacctcaggg
      961 tcaggcccag cagacccaga gtggcactgg acagaccatg caggtgatgc agcagatcat
     1021 taccaacaca ggagagatcc agcagatccc ggtgcagctg aatgctggcc agctgcaata
     1081 tatccgatta gcccagcctg tatcaggcac ccaagttgtc caaggacaga tccagacact
     1141 tgctaccaat gcccaacaga tcacacagac agaggtccag caaggacagc agcagttcag
     1201 ccagttcaca gatggacagc agctgtacca gatccagcaa gtcaccatgc ctgcaggcca
     1261 agacctcgcc cagcccatgt ttattcagtc agccaatcag ccctctgatg ggcagacccc
     1321 ccaggtgact ggagactgag ggcctgagct ggcaaagcca aggacaccca acacgatatt
     1381 tgccatagag ccccaggcga tggggacata ccctccctca ccagaggacc tgggacttca
     1441 ttgcctcctg caggctaaga tactggtgca ctactttcca cgcctgggga ctgagattct
     1501 acaacagaaa gatgcaatat tttttatttt cttttttcca tttttgtctc caaggaatca
     1561 atatttcaat attttgagct atgtgtccaa tgctatgaaa cgagaatatt aaataacata
     1621 tttatggcct tttcttgaaa cgtgtggttg aagaaataat tctcttgtgt gtttcctggc
     1681 ttgggcactc tccaccactg ctaaggggcg gcctgtgctc ttccttccta agggtgtaca
     1741 ggatttccac tctgccagtt ctgccctcag aaaaaaagaa aggggcagac cctttccacc
     1801 agcattcttc tctgcccctt ccccagaacc ttccgaatcc agaagatgtg gaaacatttc
     1861 ctgcctgtgg gccatgaact cattctccac agagagctgg tctcctcccc gtcccttctc
     1921 tccagaccca ggagaaccag gactttgaga accaggactt tgtgcactgc tctggccact
     1981 gttttatttt ttaaatacat taaagattgt gctcatctcc gttgctgcat ggactccaga
     2041 ctgcatgaaa tgcaataaat cttgttttcg gtacttgaga aaaaaaaaaa aaaaaaaaaa
     2101 a
//
