LOCUS       NM_020045                965 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus NFU1 iron-sulfur cluster scaffold (Nfu1), transcript
            variant 2, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_020045
VERSION     NM_020045.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   2  (bases 1 to 965)
  AUTHORS   Ganesh,S., Tsurutani,N., Suzuki,T., Ueda,K., Agarwala,K.L.,
            Osada,H., Delgado-Escueta,A.V. and Yamakawa,K.
  TITLE     The Lafora disease gene product laforin interacts with HIRIP5, a
            phylogenetically conserved protein containing a NifU-like domain
  JOURNAL   Hum Mol Genet 12 (18), 2359-2368 (2003)
   PUBMED   12915448
REFERENCE   3  (bases 1 to 965)
  AUTHORS   Lorain,S., Lecluse,Y., Scamps,C., Mattei,M.G. and Lipinski,M.
  TITLE     Identification of human and mouse HIRA-interacting protein-5
            (HIRIP5), two mammalian representatives in a family of
            phylogenetically conserved proteins with a role in the biogenesis
            of Fe/S proteins
  JOURNAL   Biochim Biophys Acta 1517 (3), 376-383 (2001)
   PUBMED   11342215
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK145558.1, AK003730.1 and CD775268.1.
            
            On Dec 25, 2009 this sequence version replaced NM_020045.2.
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the coding region, compared to variant 1, which results in a
            protein (isoform 2) that is one amino acid shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB195443.1, BC018355.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                AK145558.1         2-54
            54-937              AK003730.1         2-885
            938-965             CD775268.1         1-28                c
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 37.76 cM"
     gene            1..965
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /note="NFU1 iron-sulfur cluster scaffold"
                     /db_xref="GeneID:56748"
                     /db_xref="MGI:MGI:1913290"
     exon            1..124
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            125..225
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            226..361
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            362..428
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            429..549
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            550..610
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            611..785
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     exon            786..952
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      917..922
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /note="hexamer: AATAAA"
     polyA_site      952
                     /gene="Nfu1"
                     /gene_synonym="0610006G17Rik; CGI-33; Hirip5"
                     /note="major polyA site"
ORIGIN      
        1 gagtctgcgt aggacttgga gacaagaagg aggcgggtcc gcgcaagcgc actggcactg
       61 aagtgatggc ggcggccgag cgggcatggg gagcagcggt cggtgtagtc cggctgtgca
      121 ggcggttctg tcatgtagcg actccacaca cctttaagaa acaacctctg catcaatatg
      181 tacggagacc acttttcccg ctgcgcgcac ccttgtgtaa cacagtacga ttcatgttta
      241 ttcaaacaca agacacccca aatcccaaca gcttaaagtt tataccagga aagccggttc
      301 ttgagacgag gaccatggat ttccccaccc ctgctgcagc tttccgctcc cctctggcca
      361 ggcagttatt cagaattgaa ggtgtgaaaa gcgtcttctt cggaccagat ttcatcacag
      421 tcacaaagga gaatgaagag ttagactgga atttactgaa accagacatt tatgccacaa
      481 ttatggactt ctttgcatct ggcttacccc tagtgaccga ggagacgcct ccgcctccgg
      541 gagaagcagg ctctgaggaa gatgacgaag tcgtggcaat gattaaagaa ctgctagata
      601 ctagaataag gccaactgtg caggaggatg ggggcgacgt gatctacagg ggctttgaag
      661 atggcatcgt gcggctgaag ctccagggct cctgcaccag ctgccccagc tccatcatca
      721 ccctgaagag cgggattcag aacatgctgc agttttatat tccagaagtg gaaggtgtgg
      781 agcaggtgat ggatgatgac gaatcagatg aaaaagaagc aaattcatct taaataatct
      841 gcattttctt tggccacaac cattggacct atctttactg atcctgtaat tatagtctct
      901 gctatggaag tttattaata aaaggtttcc ttcctccaga atgatataaa taaaaaaaaa
      961 aaaaa
//
