LOCUS       NM_001405097            5187 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus nuclear factor related to kappa B binding protein
            (Nfrkb), transcript variant 3, mRNA.
ACCESSION   NM_001405097 XM_006510218
VERSION     NM_001405097.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5187)
  AUTHORS   Min,J.N., Tian,Y., Xiao,Y., Wu,L., Li,L. and Chang,S.
  TITLE     The mINO80 chromatin remodeling complex is required for efficient
            telomere replication and maintenance of genome stability
  JOURNAL   Cell Res 23 (12), 1396-1413 (2013)
   PUBMED   23979016
REFERENCE   2  (bases 1 to 5187)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 5187)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC167244.2.
            
            On Apr 20, 2022 this sequence version replaced XM_006510218.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.9054.1,
                                           SRR9219380.21804.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-69                AC167244.2         115481-115549
            70-242              AC167244.2         118156-118328
            243-444             AC167244.2         121242-121443
            445-572             AC167244.2         123982-124109
            573-747             AC167244.2         125602-125776
            748-885             AC167244.2         126279-126416
            886-959             AC167244.2         126999-127072
            960-1044            AC167244.2         127839-127923
            1045-1225           AC167244.2         128428-128608
            1226-1334           AC167244.2         129218-129326
            1335-1461           AC167244.2         129856-129982
            1462-1527           AC167244.2         130217-130282
            1528-1607           AC167244.2         131335-131414
            1608-1651           AC167244.2         131514-131557
            1652-1712           AC167244.2         132293-132353
            1713-1887           AC167244.2         132734-132908
            1888-1994           AC167244.2         134830-134936
            1995-2118           AC167244.2         138552-138675
            2119-2198           AC167244.2         139124-139203
            2199-2413           AC167244.2         139343-139557
            2414-2684           AC167244.2         139646-139916
            2685-2897           AC167244.2         140456-140668
            2898-3665           AC167244.2         143296-144063
            3666-3772           AC167244.2         148255-148361
            3773-3908           AC167244.2         149093-149228
            3909-5187           AC167244.2         149334-150612
FEATURES             Location/Qualifiers
     source          1..5187
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 16.86 cM"
     gene            1..5187
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /note="nuclear factor related to kappa B binding protein"
                     /db_xref="GeneID:235134"
                     /db_xref="MGI:MGI:2442410"
     exon            1..69
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            70..242
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..4034
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /note="isoform 3 is encoded by transcript variant 3;
                     DNA-binding protein R kappa-B"
                     /codon_start=1
                     /product="nuclear factor related to kappa-B-binding
                     protein isoform 3"
                     /protein_id="NP_001392026.1"
                     /db_xref="GeneID:235134"
                     /db_xref="MGI:MGI:2442410"
                     /translation="MDSLDHMLTDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLE
                     DPEIFFDVVSLSTWQEVLSDSQREHLQQFLPRFPADSVEQQRELILALFSGENFRFGN
                     PLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEM
                     ARRSGPALPFPHKHHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEATLDL
                     QEKFSFEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKLMLKKH
                     HEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKK
                     IKLIKSEAEDLAEPLSSTEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINEISSSFF
                     SLLLEILLLESQASLPMLEDRVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGES
                     RAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFHLWLETKDQAFCKENEDSSDA
                     MTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFD
                     KETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPD
                     VTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAK
                     ARKALQQKPKPPSKVKSSNKEGSTKGLSGPSEQSQMSLSDSSMPPTPVTPVTPTTPAL
                     PTPISPPPVSAVNRSGSSTVSEPAQSSSGVLLVSSPTMPQLGTMLSPASIQTPPSSQA
                     TARVVSHSSSAGLPQVRVVAQPSLPAVSQQSVGPAQPLPQMPAGPQIRVPVTATQTKV
                     VPQAVMATVPVKGQTAAASVQRPGPGQTGLTVTNLPAAVSPVSKTAMSSPGNSAPSAS
                     TTAVIQNVTGQNIIKQVSITGQLGVKPQTGSSIPLTATNFRIQGKDVLRLPPSSITTD
                     AKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHAAD
                     SPAKAPSASVPSSAPAGTTVVKVTPDLKPTETANSAFRLMPALGVSVADQKGKNTVAS
                     SEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSINAA
                     VSKTVAVASGATSTPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPM
                     KGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQ
                     GQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ"
     exon            243..444
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            445..572
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            573..747
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            748..885
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            886..959
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1044
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1225
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1334
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1461
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1527
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1607
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..1651
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1712
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1887
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1994
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2118
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..2198
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2413
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2414..2684
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2685..2897
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2898..3665
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3666..3772
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3773..3908
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3909..5187
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5169..5174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5187
                     /gene="Nfrkb"
                     /gene_synonym="A530090G11Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcgggagcga gcgcgtttcg gagcccacgg cccgacgaac cccgggtgag acccgcggac
       61 tctgctgagg gtgtattttt atgtagtcta cctgtggaga agaagcaatg gattccttgg
      121 accacatgct gacagatccc cttgaacttg gtccttgtgg agatggtcac agtacaggaa
      181 tcatggagga ctgccttctg ggtggtacca gggttagtct gcccgaagac cttctggagg
      241 atcccgagat attctttgat gtcgtcagcc tgtccacatg gcaggaagta ttaagtgact
      301 ctcagcgtga gcacctccag cagttcctgc ctcggtttcc tgcggacagt gtggagcagc
      361 agagggagct catccttgcc ctattcagtg gggagaactt ccgcttcgga aacccgctgc
      421 acatcgccca gaagctcttc cgagatggac actttaaccc tgaggtggtc aagtatcgtc
      481 agctctgctt caagtcacag tacaagcggt atctcaactc ccaacaacag tatttccacc
      541 ggctgctgaa acagattctt gcttccagga gtgatctctt ggagatggct cgtaggagtg
      601 gccctgctct tccctttcca cacaagcacc attcaccgtc ccgaagcccc gaggagcggg
      661 agtggcggac ccagcagcgt tacttgaaag tcttgaggga agtgaaggag gaatgtgggg
      721 acactgctct gtcctctgat gaggaggcca cgttggattt acaagaaaaa ttttcttttg
      781 aagatctcag ctcatggctt ccaagctctc cagcacgttc tcctagtcct gcggtgcccc
      841 tgagggtggt gcccacgctt tccaccacgg atatgaaaac tgcagataaa atagaactgg
      901 gggacagtga cctgaagtta atgttaaaga agcaccatga gaagcggaaa catcaaccag
      961 atcacccaga ccttttgaca ggggacctga ccctcagtga catcatgact cgagtaaatg
     1021 ccggcaggaa gggctcccta gcagccttgt atgatttggc tgttcttaaa aaaaaggtga
     1081 aggaaaagga ggagaagaaa aagaagaaaa taaagttgat taagtcggaa gcagaggatc
     1141 tggctgagcc cctaagcagt actgaagggg tcccaactct ctcacaggcc ccctctcccc
     1201 tggcaatatc gtctatcaag gaggaacccc tggaagacat caagccttgc cttggaatca
     1261 atgaaatatc ttccagtttt ttctctcttc tgttagagat cttgctgctg gaaagtcagg
     1321 ctagccttcc tatgctggag gatcgagttt tggactggca gtcttctcca gccagctccc
     1381 tcaacagctg gttctctgct gcccccaact gggctgagtt ggtgttgcct gctctgcagt
     1441 atcttgctgg agaaagccga gcggttcctt ctagtttctc tccatttgtt gaattcaaag
     1501 agaaaaccca gcagtggaaa ttgcttggtc aatctcaaga taatgaaaag gaattagctg
     1561 ctctcttcca cctgtggctg gaaaccaaag accaggcctt ctgtaaggaa aatgaagaca
     1621 gctcagatgc catgacacct gtccctcgag taagaactga ctatgtggtt cggcctagca
     1681 caggagagga gaaacgggtt tttcaagaac aggagcgtta caggtatagc caaccccata
     1741 aggcattcac ctttcgcatg catggctttg agtctgtggt ggggccagtg aagggcgtgt
     1801 ttgacaagga gacctccctc aacaaggctc gtgagcattc actgctgcgc tctgaccggc
     1861 ctgcctatgt caccattctg tctcttgttc gggatgctgc agctcggctg cctaatggag
     1921 aaggcactcg ggcagagatc tgtgaactgc tcaaggactc tcagtttctg gctccagatg
     1981 tcaccagcac tcaggtgaac acagtggtga gtggcgcact ggatcgattg cattatgaga
     2041 aagacccttg tgtgaaatat gacatcggtc ggaagctgtg gatctacctg catcgtgacc
     2101 ggagtgagga agagtttgaa cggattcatc aagctcaagc agcggcagct aaagccagaa
     2161 aagctcttca acaaaaaccc aagccgccat ccaaggtgaa gtccagtaat aaggagggct
     2221 ccacgaaggg ccttagcggt ccttccgagc agagccagat gagcctcagt gactctagca
     2281 tgccgcccac cccagttacg cctgtaacac ccaccacgcc agcattgccc acccccatct
     2341 ctcctccacc cgtgtcagcg gtgaacagaa gtggctctag cacggtctct gagccagccc
     2401 agtctagttc aggtgtgctt ctggtgtcct caccgacaat gccacagcta gggacgatgc
     2461 tttccccagc ttccatccag actccaccca gttctcaggc cactgctcgg gttgtcagcc
     2521 attccagctc agcaggacta ccccaggttc gggtggtagc ccagcccagc cttcctgctg
     2581 tttcccagca gtcagtaggg ccagcacagc cactacccca gatgccagca ggaccacaga
     2641 ttcgtgtgcc agtcactgct actcaaacca aagtagtacc ccaggcagtt atggcaacag
     2701 ttccagtcaa ggggcaaact gcagcagcct ctgtgcaacg gcctggacct gggcagacag
     2761 ggctcacagt gacgaatctt ccggctgcag tcagccccgt gagcaagaca gccatgagtt
     2821 ctcctgggaa ctctgctcca agtgcctcca ccacagccgt tattcagaac gtcacaggac
     2881 agaacatcat caagcaggtg tcgatcactg gacagcttgg tgtgaagccc cagacaggca
     2941 gcagcattcc actcacagcc acaaacttcc gtatccaggg taaggatgta ctgcgcctgc
     3001 cgccttcttc catcaccaca gatgccaagg gccagacggt tttgagaatc actccagaca
     3061 tgatggccac attggccaag tctcaggtta ccacagtcaa actgactcag gacctctttg
     3121 gagcaggaag tggcactgca ggcaaaggca tctctgctac cttgcatgtt acttccaacc
     3181 ctgtccacgc ggctgacagc cctgccaagg ccccttcagc cagtgtccct tcatcagctc
     3241 cagcaggtac tactgtggtc aaagtaactc ctgatctcaa gccgacagaa actgcaaatt
     3301 cagcttttcg cttgatgcca gctcttggtg taagtgtggc agatcagaag ggaaagaaca
     3361 cagtggcctc ttcagaagca aaacctgccg ccacaatccg catcgtgcag gggctgggag
     3421 tgatgccccc taaagcaggc cagaccatta ctgttgcagc acatgcaaag caaggagcct
     3481 ctgttgctgg agggtctgga actgtccatt cttcaacggt gtccttaccc agtataaatg
     3541 ccgctgtgtc aaagactgtg gctgtggcct ctggggcaac aagcaccccc atcagcatcg
     3601 ggactggagc ccccaccgtg cgacaggttc ctgttaacac tacagttgtg tccacatccc
     3661 agtctgggaa actgcctacc agaatcacag ttcctctttc tgtgattagc cagccaatga
     3721 agggcaagag cgtggtcaca gcccccatca tcaaaggcaa ccttggagcc aatctcagtg
     3781 ggctgggtcg caacatcatc ctcacgacca tgccagcagg taccaaactc attgctggca
     3841 ataagccagt gagtttcctc actgctcagc agttgcagca gcttcagcaa caaggtcagg
     3901 ctacacaggt gcgcatccag accgtcccgg catcccatct gcaacagggc acggcttctg
     3961 gctcctccaa agcagtgtcc actgttgttg tgaccacagc tccatctcct aaacaagcac
     4021 ctgagcagca gtgaccgagg agaggcggct tctctaagag accaggcccg gtggatctcg
     4081 gccgacagaa agggagcagc aggaggctgc atcgttcttc tgagctgtcc tgcttgaggc
     4141 agggtggtgg agagtgatgg caactgcggc ctaggttctg ctgccacgct ccagagtgaa
     4201 gctctgaaag gggtccctct ttagggctcc agggataatc tgtctagtcc aggaagagag
     4261 aacatcagag tcttgggagg tcacagtcac acaagccagg gttacctccc gagtgttgga
     4321 tgtccaggga gcaggcctgc cagttgctga gtgggccggc agggaataag cctcattcta
     4381 tgtgaggttt tactttttag tttctgatcc tcttggtgac ttgttgagat gtgagttttg
     4441 tgtccagaaa atttttgtgt aacttatttt tttaaagaac ctactatatg tcttttatca
     4501 aatagaaacc tgggctttag tgcccctaaa ctgatcactt accccttcaa ccagaatgag
     4561 aacatagcaa ggctcttagt aggttggtgg cttacttgat agtggagagg ttatatagta
     4621 agaaatgtag gccatgaggt agcatggacc cctcaagtgg gactagttca gcacagtgta
     4681 ctgaatatga gtgtctgatc ttggttgtcc ctgcgtcttc tcctgtgggg ttatcctcaa
     4741 caagcctgtt cacatggagg ttcagagctg ttggacaaga gagtagggaa agccggtggg
     4801 atgctgctct cagagcactt gcttacagcc cagacattgc acattctcct tgctgtacaa
     4861 cagccattgc aaaccagacc cttggagctg gccacctgac tggaacatag aagaaatggt
     4921 taggtagggg caggggtagg cactgcctgg cagtgccagc tagaggagaa gtgagtaagt
     4981 ttggtgtttt tattcctggc catttcacat ttcttagcca ccatcagcca cagacagagc
     5041 tcagagggta ctttacaaag tccaagtact ttatggactg cttgtagctt gctgtggtgc
     5101 aggggtgggt gggaaaacct ttctgcaggg atagggcttc cttgtctctt tgtgaaagta
     5161 tccaaattat taaaaatgta tctttaa
//
