LOCUS       NM_010905               9528 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus nuclear factor I/A (Nfia), transcript variant 2, mRNA.
ACCESSION   NM_010905 NM_177176
VERSION     NM_010905.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9528)
  AUTHORS   Clemot-Dupont,S., Lourenco Fernandes,J.A., Larrigan,S., Sun,X.,
            Medisetti,S., Stanley,R., El Hankouri,Z., Joshi,S.V.,
            Picketts,D.J., Shekhar,K. and Mattar,P.
  TITLE     The chromatin remodeler ADNP regulates neurodevelopmental disorder
            risk genes and neocortical neurogenesis
  JOURNAL   Proc Natl Acad Sci U S A 122 (3), e2405981122 (2025)
   PUBMED   39808658
REFERENCE   2  (bases 1 to 9528)
  AUTHORS   Bessa,P., Newman,A.G., Yan,K., Schaub,T., Dannenberg,R., Lajko,D.,
            Eilenberger,J., Brunet,T., Textoris-Taube,K., Kemmler,E., Deng,P.,
            Banerjee,P., Ravindran,E., Preissner,R., Rosario,M. and
            Tarabykin,V.
  TITLE     Semaphorin heterodimerization in cis regulates membrane targeting
            and neocortical wiring
  JOURNAL   Nat Commun 15 (1), 7059 (2024)
   PUBMED   39152101
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9528)
  AUTHORS   Campbell,C.E., Webber,K., Bard,J.E., Chaves,L.D., Osinski,J.M. and
            Gronostajski,R.M.
  TITLE     Nuclear Factor I A and Nuclear Factor I B Are Jointly Required for
            Mouse Postnatal Neural Stem Cell Self-Renewal
  JOURNAL   Stem Cells Dev 33 (7-8), 153-167 (2024)
   PUBMED   38366751
  REMARK    GeneRIF: Nuclear Factor I A and Nuclear Factor I B Are Jointly
            Required for Mouse Postnatal Neural Stem Cell Self-Renewal.
REFERENCE   4  (bases 1 to 9528)
  AUTHORS   Keeley,P.W., Trod,S., Gamboa,B.N., Coffey,P.J. and Reese,B.E.
  TITLE     Nfia Is Critical for AII Amacrine Cell Production: Selective
            Bipolar Cell Dependencies and Diminished ERG
  JOURNAL   J Neurosci 43 (49), 8367-8384 (2023)
   PUBMED   37775301
  REMARK    GeneRIF: Nfia Is Critical for AII Amacrine Cell Production:
            Selective Bipolar Cell Dependencies and Diminished ERG.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9528)
  AUTHORS   Ong,A.L.C., Kokaji,T., Kishi,A., Takihara,Y., Shinozuka,T.,
            Shimamoto,R., Isotani,A., Shirai,M. and Sasai,N.
  TITLE     Acquisition of neural fate by combination of BMP blockade and
            chromatin modification
  JOURNAL   iScience 26 (10), 107887 (2023)
   PUBMED   37771660
  REMARK    Erratum:[iScience. 2023 Oct 22;26(11):108257. doi:
            10.1016/j.isci.2023.108257. PMID: 37920664]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9528)
  AUTHORS   Fletcher,C.F., Jenkins,N.A., Copeland,N.G., Chaudhry,A.Z. and
            Gronostajski,R.M.
  TITLE     Exon structure of the nuclear factor I DNA-binding domain from C.
            elegans to mammals
  JOURNAL   Mamm Genome 10 (4), 390-396 (1999)
   PUBMED   10087299
REFERENCE   7  (bases 1 to 9528)
  AUTHORS   Chaudhry,A.Z., Lyons,G.E. and Gronostajski,R.M.
  TITLE     Expression patterns of the four nuclear factor I genes during mouse
            embryogenesis indicate a potential role in development
  JOURNAL   Dev Dyn 208 (3), 313-325 (1997)
   PUBMED   9056636
REFERENCE   8  (bases 1 to 9528)
  AUTHORS   Kulkarni,S. and Gronostajski,R.M.
  TITLE     Altered expression of the developmentally regulated NFI gene family
            during phorbol ester-induced differentiation of human leukemic
            cells
  JOURNAL   Cell Growth Differ 7 (4), 501-510 (1996)
   PUBMED   9052991
REFERENCE   9  (bases 1 to 9528)
  AUTHORS   Ang,S.L., Wierda,A., Wong,D., Stevens,K.A., Cascio,S., Rossant,J.
            and Zaret,K.S.
  TITLE     The formation and maintenance of the definitive endoderm lineage in
            the mouse: involvement of HNF3/forkhead proteins
  JOURNAL   Development 119 (4), 1301-1315 (1993)
   PUBMED   8306889
REFERENCE   10 (bases 1 to 9528)
  AUTHORS   Inoue,T., Tamura,T., Furuichi,T. and Mikoshiba,K.
  TITLE     Isolation of complementary DNAs encoding a cerebellum-enriched
            nuclear factor I family that activates transcription from the mouse
            myelin basic protein promoter
  JOURNAL   J Biol Chem 265 (31), 19065-19070 (1990)
   PUBMED   1699939
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL670195.10, AF326553.1, AL671238.13, AL670260.10 and AW122288.1.
            
            On Apr 2, 2008 this sequence version replaced NM_010905.2.
            
            Transcript Variant: This variant (2) has an alternate 5' exon, as
            compared to variant 1. The resulting isoform (2) has a different
            and shorter N-terminus, as compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK052204.1, AK054310.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-301               AL670195.10        93838-94138
            302-1910            AF326553.1         1-1609
            1911-2506           AL671238.13        215595-216190
            2507-9506           AL670260.10        2001-9000
            9507-9528           AW122288.1         1-22                c
FEATURES             Location/Qualifiers
     source          1..9528
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.52 cM"
     gene            1..9528
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="nuclear factor I/A"
                     /db_xref="GeneID:18027"
                     /db_xref="MGI:MGI:108056"
     exon            1..369
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     CDS             343..1872
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="isoform 2 is encoded by transcript variant 2;
                     nuclear factor 1 A-type; nuclear factor 1/A; TGGCA-binding
                     protein; CCAAT-box-binding transcription factor"
                     /codon_start=1
                     /product="nuclear factor 1 A-type isoform 2"
                     /protein_id="NP_035035.1"
                     /db_xref="CCDS:CCDS18373.1"
                     /db_xref="GeneID:18027"
                     /db_xref="MGI:MGI:108056"
                     /translation="MYSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKH
                     EKRMSKEEERAVKDELLSEKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPC
                     CVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPG
                     LCVQPHHIGVSVKELDLYLAYFVHAADSSQSESPSQPSEADIKDQPENGHLGFQDSFV
                     TSGVFSVTELVRVSQTPIAAGTGPNFSLSDLESSSYYSMSPGAMRRSLPSTSSTSSTK
                     RLKSVEDEMDSPGEEPFYTGQGRSPGSGSQSSGWHEVEPGLPSPSTLKKSEKSGFSSP
                     SPSQTSSLGTAFTQHHRPVITGPRASPHATPSTLHFPTSPIIQQPGPYFSHPAIRYHP
                     QETLKEFVQLVCPDAGQQAGQVGFLNPNGSSQGKVHNPFLPTPMLPPPPPPPMARPVP
                     LPMPDTKPPTTSTEGGAASPTSPTYSTPSTSPANRFVSVGPRDPSFVNIPQQTQSWYL
                     G"
     exon            370..901
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            902..967
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1042
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1160
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1288
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1417
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1596
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1762
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1854
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..9513
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4732..4737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="hexamer: AATAAA"
     polyA_site      4753
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="major polyA site"
     regulatory      9484..9489
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="hexamer: AATAAA"
     polyA_site      9508
                     /gene="Nfia"
                     /gene_synonym="1110047K16Rik; 9430022M17Rik; CTF; NF1-A;
                     NF1A"
                     /note="major polyA site"
ORIGIN      
        1 agaacgcggc gcaggcgggc gcgcgggcag ctcgcgggca cccggccggc cggcgcggga
       61 gcgggaaagg gtgcgctatg cctttaacgc ccgcgtacag tagacagtat agtggagtgt
      121 agggaaactc taggcggggt taaagttcag cgcgtggagc ggcaagagcg ctggctgctg
      181 cagttgagcc gagttggaaa tgtgaacgca agaagcaggc ttgatttttt attcctcccc
      241 ccctcctagc tctctcctcc tctctctccc tctcgcaccc acactcacgc acacctccag
      301 cccgcacaca gacgtgcacg caccccccgc cgcccggcag ttatgtattc tccgctctgt
      361 ctcacccagg atgagtttca tcctttcatt gaagcacttc tgccccatgt ccgcgccttc
      421 gcctacacat ggttcaacct gcaggcccga aagcggaaat acttcaaaaa acatgagaag
      481 cgcatgtcga aagaagagga gagggccgtg aaggatgaac tgctaagcga gaagcccgag
      541 gtcaagcaga agtgggcttc ccgacttctg gccaagttac ggaaagatat ccgacccgag
      601 taccgagagg attttgttct tacagttaca gggaaaaaac ctccatgctg tgttctttcc
      661 aaccctgatc agaaaggcaa gatgcggaga attgactgcc tccgccaggc agataaagta
      721 tggaggttgg acctcgtcat ggtgatcttg ttcaaaggta ttccgctgga aagtactgat
      781 ggcgagcgcc ttgtaaagag tccacagtgc tctaatccag ggctctgtgt ccagccccat
      841 cacatagggg tttctgtaaa ggaactcgat ttatatttgg catactttgt acatgcagca
      901 gattcaagtc aatctgaaag tcccagccag ccaagtgaag ctgacattaa ggaccagcca
      961 gaaaatggac atttgggctt ccaggacagc tttgtcacat caggtgtttt cagtgtgact
     1021 gagctagtaa gagtgtcaca aacaccaata gctgcaggaa ccggccccaa tttttctctc
     1081 tctgatttgg aaagttcttc atactacagc atgagtccag gagcaatgag gaggtctctg
     1141 cccagcacat cctctaccag ctctacaaag cgcctcaagt ctgtggagga tgaaatggac
     1201 agtcctggtg aagaaccatt ttacacaggc caagggcgct ccccagggag tggcagccag
     1261 tccagtggat ggcatgaagt agagccaggc ttgccatctc caagcacact gaagaagtct
     1321 gagaagtctg gtttcagcag cccctcccct tcgcagacct cctccctggg aacagcattc
     1381 acacagcatc accgacctgt cattacagga cccagagcaa gtccacatgc gacgccatcg
     1441 actctccact ttccaacgtc acccatcatc cagcagcctg ggccttactt ctcacaccca
     1501 gccatccgtt accaccctca ggagacgctg aaagagtttg tccaacttgt ctgtcctgat
     1561 gctggtcagc aagctggaca ggtggggttc ctcaatccca atggaagcag tcaaggcaag
     1621 gtgcacaacc cattcctccc caccccaatg ttgccgccgc cgccaccacc accgatggcc
     1681 aggcctgtgc ctctgcccat gccagacacc aagcctccaa ccacatcaac agaaggaggt
     1741 gcagcctccc ccacctcacc gacctactcg acacccagca cctcccccgc aaaccgattc
     1801 gtcagtgttg gaccacggga tccaagcttt gtaaatatcc ctcaacagac acagtcctgg
     1861 tacctgggat aaaagttgca gcatcccacc atcctccaga cagaccacct gaccccttct
     1921 caactctgta acatggacgc aacctcaacc cggcgcagtt acaacttcac tgtcagtgga
     1981 aggggagcga aaccaactcg aatcaactta tacatggaaa cagcaaacat cgtggtcaaa
     2041 cagcaaaggc cataactttt tgggattctt ttttttttct ttttttcttt ttttcttttt
     2101 ttttttcttt tttaatactt tagggactgt cgtaatttct catggtgctg gaaatggttg
     2161 ggctgtgtga catttgaagt gtttcagtgg tggcgtgagc agtaggtgaa gtggttggtg
     2221 aaggatgagc ctcgctcgtg aacttcctgt ggtaacactt gggagcctgg ccttttccca
     2281 gtatttcctg aatttgcccg tgcaggtgtg tgaccctccc tgagcatctg gagacacctg
     2341 gagcatgaaa ccttctgtaa tcgctgagat ctgtaactta caggacactc aaagggcaat
     2401 ggtttttttt gggggggggg ttgttttttt ggtttttttt tttctgtaac atattaggga
     2461 aaaaatgcag ttaagttgat ctttctttta atttggtttg gttcagcagt cagcagttac
     2521 atacataaca caacccgcaa ggacagtgaa tccgctcctg ttgcagagca atttccaaaa
     2581 agacggcaaa gactactact atcagtttgg ttgggttttt gtttttttgt tttttttttt
     2641 tttgtttttt tttgtttttt ttgttcttaa gttttgaaat gctgcactta catttaaaaa
     2701 aaaacatttt tcaacaattt caacaatgac acaaaaattc acatggaaat ggggaagatg
     2761 gtctgttttg acagaaactg acaggaatca aaacaatcga attttgaatt gagtgaagtg
     2821 caatttcatt ggatagctaa gtatctttgt aagatagaga ttgttgaaaa ttctattttt
     2881 gtttttcaag tcctcccacc ccaggactct aaattattgg ggtaaaaaac agccttgcaa
     2941 gaaaaagggg agctattttt gctttttatg ttttttattg ttaaacttgt atccctttaa
     3001 aaaaaaaccg aaggaaaatt taaaaaaaca aaaaaaatac aaaaaaaaaa tacaaatcta
     3061 atggtgcttt taccacaata tgttaactac attaaatgct aattaattat tttctgttat
     3121 caaagcacat aactcaaatg aaatcatggt atctgttaat tttataagct agaaatcact
     3181 ataatgaatt atgccaattc tgaaaaattt tacacatgta tggcaacacc tgatctatcg
     3241 gttatccaac gcttcattgt accagacatt gtccagaagt ttcaaagacc ctttgcaaac
     3301 cctgaactgg gctacgggaa aataacacga atactgataa ggacacaact atgtgtgccc
     3361 attcagatca aagtacttgt tagggaaaaa aaaaaagttc acaccctccc cgcccccccc
     3421 ccccagatgt cttgtatctt atgtttaagg gaaaaaaaag acaaaaaaaa aaagacaaaa
     3481 aaaatcaaaa aaggaaaaaa aagcagaaac aaataaacaa acaaacaaaa aaaatgcaag
     3541 tgatttttct accagacagc gaagcaccct tgcttcccat gcaatgtcac ggtttcctat
     3601 actatacata tatatgtgtt ctggtcggca aagcctgccg accagaggaa gtctctctgc
     3661 atgttctagt gttagtaact aatttttata tagctaatgt aggataaagt agagtgcatt
     3721 aagacaatat tgtaacccca ctctaggcac ttgcctttaa actgtctcag cccttcagaa
     3781 gggctcaact actgtcctat acaatcaagt gactgaaatt cctgggaaga cactttgctc
     3841 ctcacctaac cccaccccca tccctaaacg atgttgtttt gtttttattt ttttccttaa
     3901 tttgcacgaa aacagaaatt ccatatcaat gtgccttgcc ctggatagtg attatttgtg
     3961 gaattgttgc acatgctcct caattgaagg ggttttttcc ctactcaagc attcggagac
     4021 actttctgta aatgttaacc tttatgtcag ccatcgtcag tttcaacatc tagacctaaa
     4081 tagaaagtta gctgttccgc agacaggcgt agtcttgagt gtcctgtgtg gtcagtggca
     4141 gtgctattct gagctctgta gatgcttaca atgtcagtat ttgggatgtc gctgcatttt
     4201 ttttttcaat ttatttggag tctcccttta ttcctgcccc cgcccccaga tatatgaaaa
     4261 tatgcaatac ctgcttatat catgtagaaa agcttagcaa gtattaattt ttctttcttt
     4321 cttttttttt tttttttttt tttttttttt gtttgaccaa agtcagtgct gcacatgacg
     4381 cagtgggttt taggtgtctc tctttgtgtt ttctgtggtt tgtgatgcac gtgcgcagga
     4441 agggctcctc ttagagaagc agccaaactg tgaagcacta agctgaccct gcttcaagca
     4501 attttgtttt tacaactgtt cctttcacaa gcaagcctta aaaaaagaga aaaagaaaaa
     4561 aaaaagacaa cttcctttct cttcagaccc ccacacccac ttttcttagc agacggcagt
     4621 caatccacat tcaataaaaa gtacataatg cccattttta tatgcacgtt tttaaacttc
     4681 caagttctga aaattgttta ctggttatct ctatttaagg aaaaaaaata aaataaaaca
     4741 ttttggattt tcatatgtgt ctgataagtg gttgtatagt cgtttggcgc tgttgtatgg
     4801 tgtgattgtc agtgtatggt gtcacttcct atagccagca gcagactttg ccttccctat
     4861 agcacttagc tgagcattac tttatgatga catatgtgca ctaaaaaaaa aaaaaaaaaa
     4921 aaaaaaaaaa aaaaaaaaaa ggagaaagaa aaaaaaagaa agaaaaaata gcagctttca
     4981 gtgcttcaca gtgaagggaa aaaagcctag acaaacattt tgtcagaacc ttgcgaaatg
     5041 ccaaggtatt accagtaaat tggttgtata tacaataaaa ttgcaccctt tttttaaaca
     5101 aaacaaacta agcaatagtt tgggcagttc tagttgtttt tagtgagcat gttgtagtct
     5161 cgactgcaaa gagagagaat aaactgccca ctcagaagat atgtaatttg tatcgttgta
     5221 tagttttatt gattacactg atttattcta ccctatttta taatgcagga cttttgtaat
     5281 gttgtctaaa tgaggaaaca tttctgtcaa attagcctag tgaaatctct gattgttcat
     5341 tacaaaggca gcgttcacag cattgcttct tcttcttcct tctccacctc cttgtgggaa
     5401 cgggattaag tttaaaactt tcccgtttct tttttgttcg gttggtttgg gttttttttt
     5461 ttctttttct acttttaaag tatttaaatg caattatttt tctgccaatg gtatagccta
     5521 tgcctatgct tgagaagtgt aggtctactg aagaaccatt acaaatggac gtcagaggtg
     5581 tgctgtactt ttgaaggtat tttattgtat taggtttaat gaagctaaaa gtagggaact
     5641 ctcaacagat ttgcaggagg aaaaaaaatg tttttaaagg ctctcaacca ctgtggaggc
     5701 agcatagggt gacagcaacc aaggattaag tagtcagtac accaagttct ggtctgctca
     5761 tgcttcattg tccagaaagc agcaggaaat tgtagttccg ttgtcatcaa gcaggaagca
     5821 aatgcaacac cgaccaaggc agtttaggtc aagagctgag ccaaggtgct tgaggaaggc
     5881 tttgctacag gagtgtagag acagacagcc ccaagagctg tcagcattgg aagccagact
     5941 tgattctgag acatgttgaa ttgctttttc ctctcccatc aaatggcatt aacacaattg
     6001 gtaaagatgg tccctcaaat gactcccccc cccccatttt tgtctttggg aactgaagtc
     6061 agaggcacca agtctaactc tcagcatttt tccaataaat gttctccctt ggcccctctc
     6121 ctggccacca caaagctcct tttctaaact gtcctgggca gaagtcttct ctggtgccct
     6181 tctcccatcc tccagccctt cacttcccac tgaggttgtc tctttactgc ctggcatgac
     6241 atctaaaagc tcactgccta tgcagggctc actccccacc atccggatgg cctcccacag
     6301 gccctccagc ctcaatcctc cgtgcttcct tttttccttt cccaacagtc caagagcgca
     6361 ggatccaact ttctagtcac gctgttctgt attcagtcag cccacaagaa tatgcaaact
     6421 ccatctcaaa actactgtct ttcaccttcc caaatctcta tcctcgtgtg cttcaagctc
     6481 tataacaacc atatcatgag gtatttgcaa aggaaaacat tttctcccat gatttgtttt
     6541 ttgttgttat tgttgttggg ttggggattt tttttgtttg tttcattgtt ttggttttgg
     6601 ttttgatggg gactggtctt taagactgtc atttgatatt tttttacatc agagtttatc
     6661 ccacagtccc ccatctctcc ctcctccttc cctccctgtc tccttctctc tttctcactg
     6721 tctgtctctc tggttttctt ttgctgcttc ttcccttctg gtttctggta gcaggcctcc
     6781 attgaactgt tgtaaaatac aagaagtgtg gtcagtaagg agagttgggg tggtgccttc
     6841 cagcctgccc gccagtccat cctagacact cccagaggct gctagctccg cccctctggc
     6901 atggctttcc tttcccatcg ccttcggagg ccattttgtc ttgaagtcaa tgcatgctcg
     6961 tgctgttcga cagtaaccta ctctgccttc tccacctccg aggctgtgca ttcatccaat
     7021 tagtgtcatg aatgtttccc ctttattttt ccaataaaaa aaagcagtgg gatgaaaatt
     7081 gctttgatat atagcaggta tattgaagct attccatagc acttaactgt agtgaatact
     7141 gtgtcaccag ttctgaaatc aatttaatgt ttaatgcaaa tccattacat ggtgctatta
     7201 caggctgaca aaatgattca cacgaatgtg acaactcggg ctcagttcac tctgcttccc
     7261 aacagtgtaa atgcatagca gtgtttacct gcatgagaac tatgcactaa tctatctgaa
     7321 gaaaaaaaaa aactatatca actttggtat ctactttccg tttacttcaa tccttgcctt
     7381 tttggtcatt gttataatgc cagctttagg acagaaagaa ttataagaaa accagcataa
     7441 tacctgatat attaaaatgt agtgcctgtg aaacctgtat tatactgctc ttctgaagta
     7501 agacttttct acaccggtag ccttcgctgt ctgtcagtca ggacctctgg tataggtgat
     7561 gtaaaataac cgtacaatat tatgcatgct atcccataat gcttagtgac tgtatgatat
     7621 tactcagagt tctgttagac tttttttctg cctcggttct tatcggctag gtttgaggta
     7681 tttcactgag aacgtgaact cggtcttcct tccagctgtc gtcaggatct tggaggtgta
     7741 cacttactta aattcagtat tacttgtgtg tgttttcatt tttttgttgt tgttttttgt
     7801 ttttgttttg ttttgttttt tgttttgttt tgttttcttt tgtttctcct aagggacaag
     7861 catgggtgtt tgatttcaga aatcagtatc tggtgagatt tttgtctcaa aactaccatt
     7921 tgaatttcaa gaactctgct gcaaaaccac tctgagaatg tttccaagtg agagtcactt
     7981 tcttgaccct caagagaagc tagacgacac agaagaacct taatggacag tgtacccatg
     8041 cttgatctgt ctcacaccag acttccttgt agtaaaaaga aaaacaaaac aaaacaaaag
     8101 aactttaaga aatcacttag ctgtttagtt acatgcacag atgcaatatt ttcttcaaaa
     8161 atataactct gtacaaactt tgggcccgat tcataagaaa gaagtttgct attaacacgg
     8221 gattttaaaa aatatgctct ctctctctct gctctctctc tctctctaaa tttggatata
     8281 ttttcttccc aaattgaata tttcctttgt ttaactcccc ccccccccaa tagcacccat
     8341 ttgcctctca ttctcccaag ggttgcatta aggaagttgg agggatgcta tatggggact
     8401 ggatcccagt aaggctcaca aggctaaggg gaacttaagt atgggataca gcacatggat
     8461 gcacccctct gtgtgtcagg catcctccat gtggactcac tgtgctgttg ggactgaaac
     8521 actaactttg taaaatgtgt ctggaccaca agaggataca ggagaagtgc tacctctgat
     8581 ctaactagag caagctcatg gcagaaaata tcacaaactt taaaatgtga agattcctgt
     8641 ctctcccgtg gttttaaagg caagtggtgt ccaagaaaca gagcatcctt cctgccgttc
     8701 aacgctcagc ttttccgaaa acctaaagct tgtgttctct ttgctttgac tgcaaattgt
     8761 actgctcttg tttttttaat ttttttcttg gtcatggtct gtaaatttgc tttttttctt
     8821 tctttctttt ttaacctgtt attgtccact aaaggtctta gatgtctggc catgtgagaa
     8881 tgcagtaagg gggctgccag ctctcttctc cctcagacca ttgtctcccc gctgaactcg
     8941 gctgccttgc caccgaggtg ccagccaggc tagaggagtg ccagcaggtc ccagtaggtc
     9001 cttaggaagg ctgtcaaggc ccagtccatg gttccttctc tgcttctcct acataccttt
     9061 cccatcacac atgaaaaaag aaaaaaacaa atctgctcag agtgcctctg gtttcttttc
     9121 aaattgtggg gggaaggatt aaaaacttca aatgatggaa aaagagatct cttgtgaaac
     9181 gaaacgcccc gtgttaataa cttggtctga aattgttttt atgagccggg ccccctgtgc
     9241 ctctagcata tgtgtattga ctctcatagt tacccttttc gtttactgtg ttctgtgaaa
     9301 acttgtaatt ggttgagaat cactgtgggc gtccattctt atcaactaaa tctccacagg
     9361 gtttttgtgc tggtgtggat tagtttaact cttgtattca accgttagtg ctaccacctt
     9421 ctcacattac aatacaatta ctggaagcaa gtactgcatt tcctatgcaa caaaaaaagg
     9481 aaaaataaaa aaaaaattgc taatgctacg gaaaaaaaaa aaaaaaaa
//
